Silencing of desmoplakin decreases connexin43/Nav1.5 expression and sodium current in HL-1 cardiomyocytes

Molecular Medicine Reports

Volumn 8, Issue 3, 2013, Pages 780-786

  Zhang, Qianhuan ^a   Deng, Chunyu ^a   Rao, Fang ^a   Modi, Rohan M ^b   Zhu, Jiening ^a   Liu, Xiaoying ^a   Mai, Liping ^a   Tan, Honghong ^a   Yu, Xiyong ^a   Lin, Qiuxiong ^a   Xiao, Dingzhang ^a   Kuang, Sujuan ^a   Wu, Shulin ^a  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Arrhythmogenic right ventricular cardiomyopathy; Connexin43; Desmoplakin; Small interfering RNA; Sodium current

Indexed keywords

CONNEXIN 43; DESMOPLAKIN; FLUORESCENT DYE; SMALL INTERFERING RNA; SODIUM CHANNEL NAV1.5;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL JUNCTION; CELL LINE; CONTROLLED STUDY; FLOW CYTOMETRY; GENE MUTATION; GENE SILENCING; HEART CONDUCTION; HEART MUSCLE CELL; IMMUNOFLUORESCENCE; MOUSE; MUSCLE CONTRACTION; NONHUMAN; PATCH CLAMP; PROCEDURES; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA INTERFERENCE; SCRAPE LOADING DYE TRANSFER; SODIUM CURRENT; WESTERN BLOTTING;

ANIMALS; CELL LINE; CONNEXIN 43; DESMOPLAKINS; GAP JUNCTIONS; MEMBRANE POTENTIALS; MICE; MICROSCOPY, CONFOCAL; MYOCYTES, CARDIAC; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PATCH-CLAMP TECHNIQUES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SODIUM;

EID: 84881137449     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1594     Document Type: Article

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