Neurobiology of addiction versus drug use driven by lack of choice

Current Opinion in Neurobiology

Volumn 23, Issue 4, 2013, Pages 581-587

  Ahmed, Serge H ^a,b   Lenoir, Magalie ^a,b   Guillem, Karine ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSTITUT DES MALADIES NEURODÉGÉNÉRATIVES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIORAL SCIENCE; COCAINE DEPENDENCE; COPING BEHAVIOR; DECISION MAKING; DISPLACEMENT BEHAVIOR; DRUG CHOICE; DRUG DEPENDENCE; DRUG PREFERENCE; DRUG SELF ADMINISTRATION; DRUG USE; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; NEUROBIOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 84881113353     PISSN: 09594388     EISSN: 18736882     Source Type: Journal    
DOI: 10.1016/j.conb.2013.01.028     Document Type: Review

References (87)

1. Ahmed S.H. Validation crisis in animal models of drug addiction: beyond non-disordered drug use toward drug addiction. Neurosci Biobehav Rev 2010, 35:172-184.
2. Koob G.F. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 1992, 13:177-184.
3. Roberts D.C., Corcoran M.E., Fibiger H.C. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacol Biochem Behav 1977, 6:615-620.
4. Roberts D.C., Koob G.F., Klonoff P., Fibiger H.C. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol Biochem Behav 1980, 12:781-787.
5. Thomsen M., Han D.D., Gu H.H., Caine S.B. Lack of cocaine self-administration in mice expressing a cocaine-insensitive dopamine transporter. J Pharmacol Exp Ther 2009, 331:204-211.
6. Mirenowicz J., Schultz W. Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli. Nature 1996, 379:449-451.
7. Pan W.X., Schmidt R., Wickens J.R., Hyland B.I. Dopamine cells respond to predicted events during classical conditioning: evidence for eligibility traces in the reward-learning network. J Neurosci 2005, 25:6235-6242.
8. Day J.J., Roitman M.F., Wightman R.M., Carelli R.M. Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens. Nat Neurosci 2007, 10:1020-1028.
9. Roitman M.F., Stuber G.D., Phillips P.E., Wightman R.M., Carelli R.M. Dopamine operates as a subsecond modulator of food seeking. J Neurosci 2004, 24:1265-1271.
10. Berridge K.C. The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology (Berl) 2007, 191:391-431.
11. Salamone J.D., Correa M. The mysterious motivational functions of mesolimbic dopamine. Neuron 2012, 76:470-485.
12. Le Moal M., Simon H. Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 1991, 71:155-234.
13. Schultz W., Dayan P., Montague P.R. A neural substrate of prediction and reward. Science 1997, 275:1593-1599.
14. Montague P.R., Dayan P., Sejnowski T.J. A framework for mesencephalic dopamine systems based on predictive Hebbian learning. J Neurosci 1996, 16:1936-1947.
15. Cardinal R.N., Everitt B.J. Neural and psychological mechanisms underlying appetitive learning: links to drug addiction. Curr Opin Neurobiol 2004, 14:156-162.
16. Cacciapaglia F., Wightman R.M., Carelli R.M. Rapid dopamine signaling differentially modulates distinct microcircuits within the nucleus accumbens during sucrose-directed behavior. J Neurosci 2011, 31:13860-13869.
17. Reynolds J.N., Hyland B.I., Wickens J.R. A cellular mechanism of reward-related learning. Nature 2001, 413:67-70.
18. Montague P.R., Hyman S.E., Cohen J.D. Computational roles for dopamine in behavioural control. Nature 2004, 431:760-767.
19. Volkow N.D., Wise R.A. How can drug addiction help us understand obesity?. Nat Neurosci 2005, 8:555-560.
20. Di Chiara G. Drug addiction as dopamine-dependent associative learning disorder. Eur J Pharmacol 1999, 375:13-30.
21. Hyman S.E. Addiction: a disease of learning and memory. Am J Psychiatry 2005, 162:1414-1422.
22. Kalivas P.W., O'Brien C. Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacology 2008, 33:166-180.
23. Robbins T.W., Everitt B.J. Drug addiction: bad habits add up. Nature 1999, 398:567-570.
24. Koob G.F., Volkow N.D. Neurocircuitry of addiction. Neuropsychopharmacology 2010, 35:217-238.
25. Maia T.V., Frank M.J. From reinforcement learning models to psychiatric and neurological disorders. Nat Neurosci 2011, 14:154-162.
26. Schultz W. Potential vulnerabilities of neuronal reward, risk, and decision mechanisms to addictive drugs. Neuron 2011, 69:603-617.
27. Robinson T.E., Berridge K.C. Review. The incentive sensitization theory of addiction: some current issues. Philos Trans R Soc Lond B Biol Sci 2008, 363:3137-3146.
28. Carroll M.E., Lac S.T. Acquisition of i.v. amphetamine and cocaine self-administration in rats as a function of dose. Psychopharmacology (Berl) 1997, 129:206-214.
29. Ahmed S.H. Escalation of drug use. Animal Models of Drug Addiction, Neuromethods 2011, vol 53:267-292. Humana Press.
30. Ahmed S.H., Koob G.F. Transition from moderate to excessive drug intake: change in hedonic set point. Science 1998, 282:298-300.
31. Anthony J.C. Epidemiology of drug dependence. Neuropsychopharmacology: the Fifth Generation of Progress 2002, 1557-1573. Williams and Wilkins, Lippincott. K.L. Davis, D. Charney, J.T. Coyle, C. Nemeroff (Eds.).
32. Degenhardt L., Bohnert K.M., Anthony J.C. Assessment of cocaine and other drug dependence in the general population: 'gated' versus 'ungated' approaches. Drug Alcohol Depend 2008, 93:227-232.
33. Anthony J.C., Warner L.A., Kessler R.C. Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: basic findings from the National Comorbidity Survey. Exp Clin Psychopharmacol 1994, 2:224-268.
34. O'Brien M.S., Anthony J.C. Risk of becoming cocaine dependent: epidemiological estimates for the United States, 2000-2001. Neuropsychopharmacology 2005, 30:1006-1018.
35. Ahmed S.H. Imbalance between drug and non-drug reward availability: a major risk factor for addiction. Eur J Pharmacol 2005, 526:9-20.
36. Ahmed S.H. The science of making drug-addicted animals. Neuroscience 2012, 211:107-125.
37. Seddon T. A History of Drugs: Drugs and Freedom in the Liberal Age 2010, Routledge, New York.
38. Searle J.R. Freedom and Neurobiology 2007, Columbia University Press, New York.
39. Mele A.R. Autonomous Agents 1995, Oxford University Press, New York.
40. Kane R. The Significance of Free Will 1998, Oxford University Press, New York.
41. Dennett D.C. Freedom Evolves 2003, Penguin Books, New York.
42. Martin C.S., Chung T., Langenbucher J.W. How should we revise diagnostic criteria for substance use disorders in the DSM-V?. J Abnorm Psychol 2008, 117:561-575.
43. Redish A.D., Jensen S., Johnson A. A unified framework for addiction: vulnerabilities in the decision process. Behav Brain Sci 2008, 31:415-437. discussion 437-487.
44. Volkow N.D., Baler R.D., Goldstein R.Z. Addiction: pulling at the neural threads of social behaviors. Neuron 2011, 69:599-602.
45. Stein D.J., Phillips K.A., Bolton D., Fulford K.W., Sadler J.Z., Kendler K.S. What is a mental/psychiatric disorder? From DSM-IV to DSM-V. Psychol Med 2010, 40:1759-1765.
46. Alexander B.K. The Globalisation of Addiction: a Study in Poverty of the Spirit 2008, Oxford University Press, New York.
47. Alexander B.K., Beyerstein B.L., Hadaway P.F., Coambs R.B. Effect of early and later colony housing on oral ingestion of morphine in rats. Pharmacol Biochem Behav 1981, 15:571-576.
48. Solinas M., Thiriet N., Chauvet C., Jaber M. Prevention and treatment of drug addiction by environmental enrichment. Prog Neurobiol 2010, 92:572-592.
49. Stairs D.J., Bardo M.T. Neurobehavioral effects of environmental enrichment and drug abuse vulnerability. Pharmacol Biochem Behav 2009, 92:377-382.
50. Carroll M.E., Lac S.T. Autoshaping i.v. cocaine self-administration in rats: effects of nondrug alternative reinforcers on acquisition. Psychopharmacology (Berl) 1993, 110:5-12.
51. Carroll M.E., Lac S.T., Nygaard S.L. A concurrently available nondrug reinforcer prevents the acquisition or decreases the maintenance of cocaine-reinforced behavior. Psychopharmacology (Berl) 1989, 97:23-29.
52. Aigner T.G., Balster R.L. Choice behavior in rhesus monkeys: cocaine versus food. Science 1978, 201:534-535.
53. Spragg S.D.S. Morphine addiction in chimpanzees. Comp Psychol Monogr 1940, 15:1-132.
54. Nader M.A., Woolverton W.L. Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure. Psychopharmacology (Berl) 1991, 105:169-174.
55. Negus S.S. Rapid assessment of choice between cocaine and food in rhesus monkeys: effects of environmental manipulations and treatment with d-amphetamine and flupenthixol. Neuropsychopharmacology 2003, 28:919-931.
56. Paronis C.A., Gasior M., Bergman J. Effects of cocaine under concurrent fixed ratio schedules of food and IV drug availability: a novel choice procedure in monkeys. Psychopharmacology (Berl) 2002, 163:283-291.
57. Augier E., Vouillac C., Ahmed S.H. Diazepam promotes choice of abstinence in cocaine self-administering rats. Addict Biol 2012, 17:378-391.
58. Cantin L., Lenoir M., Augier E., Vanhille N., Dubreucq S., Serre F., Vouillac C., Ahmed S.H. Cocaine is low on the value ladder of rats: possible evidence for resilience to addiction. PLoS ONE 2010, 5:e11592.
59. Lenoir M., Serre F., Cantin L., Ahmed S.H. Intense sweetness surpasses cocaine reward. PLoS ONE 2007, 2:e698.
60. Lenoir M, Cantin L, Vanhille N, Serre F, Ahmed SH: Extended heroin access increases heroin choices over a potent nondrug alternative. Neuropsychopharmacology, in press.
61. Kerstetter K.A., Ballis M.A., Duffin-Lutgen S., Carr A.E., Behrens A.M., Kippin T.E. Sex differences in selecting between food and cocaine reinforcement are mediated by estrogen. Neuropsychopharmacology 2012, 37:2605-2614.
62. Le Sage M.G. Toward a nonhuman model of contingency management: effects of reinforcing abstinence from nicotine self-administration in rats with an alternative nondrug reinforcer. Psychopharmacology (Berl) 2009, 203:13-22.
63. Domingos A.I., Vaynshteyn J., Voss H.U., Ren X., Gradinaru V., Zang F., Deisseroth K., de Araujo I.E., Friedman J. Leptin regulates the reward value of nutrient. Nat Neurosci 2011, 14:1562-1568.
64. Adamantidis A.R., Tsai H.C., Boutrel B., Zhang F., Stuber G.D., Budygin E.A., Tourino C., Bonci A., Deisseroth K., de Lecea L. Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J Neurosci 2011, 31:10829-10835.
65. Kim K.M., Baratta M.V., Yang A., Lee D., Boyden E.S., Fiorillo C.D. Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PLoS ONE 2012, 7:e33612.
66. Tsai H.C., Zhang F., Adamantidis A., Stuber G.D., Bonci A., de Lecea L., Deisseroth K. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science 2009, 324:1080-1084.
67. Berridge K.C., Ho C.Y., Richard J.M., DiFeliceantonio A.G. The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. Brain Res 2010, 1350:43-64.
68. DiLeone R.J., Taylor J.R., Picciotto M.R. The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction. Nat Neurosci 2012, 15:1330-1335.
69. Kenny P.J. Reward mechanisms in obesity: new insights and future directions. Neuron 2011, 69:664-679.
70. Cameron C.M., Carelli R.M. Cocaine abstinence alters nucleus accumbens firing dynamics during goal-directed behaviors for cocaine and sucrose. Eur J Neurosci 2012, 35:940-951.
71. Opris I., Hampson R.E., Deadwyler S.A. The encoding of cocaine vs. natural rewards in the striatum of nonhuman primates: categories with different activations. Neuroscience 2009, 163:40-54.
72. Bowman E.M., Aigner T.G., Richmond B.J. Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J Neurophysiol 1996, 75:1061-1073.
73. Robinson D.L., Carelli R.M. Distinct subsets of nucleus accumbens neurons encode operant responding for ethanol versus water. Eur J Neurosci 2008, 28:1887-1894.
74. Miller W.R., Forcehimes A.A., Zweben A. Treating Addiction 2011, The Guilford Press, New York.
75. Higgins S.T., Budney A.J., Bickel W.K., Foerg F.E., Donham R., Badger G.J. Incentives improve outcome in outpatient behavioral treatment of cocaine dependence. Arch Gen Psychiatry 1994, 51:568-576.
76. Dutra L., Stathopoulou G., Basden S.L., Leyro T.M., Powers M.B., Otto M.W. A meta-analytic review of psychosocial interventions for substance use disorders. Am J Psychiatry 2008, 165:179-187.
77. Heyman G.M. Addiction: a Disorder of Choice 2009, Harvard University Press, Cambridge.
78. Potenza M.N., Sofuoglu M., Carroll K.M., Rounsaville B.J. Neuroscience of behavioral and pharmacological treatments for addictions. Neuron 2011, 69:695-712.
79. Volkow N.D., Wang G.J., Baler R.D. Reward, dopamine and the control of food intake: implications for obesity. Trends Cogn Sci 2011, 15:37-46.
80. Avena N.M., Rada P., Hoebel B.G. Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev 2008, 32:20-39.
81. Gearhardt A.N., Grilo C.M., Dileone R.J., Brownell K.D., Potenza M.N. Can food be addictive? Public health and policy implications. Addiction 2011, 106:1208-1212.
82. Ziauddeen H., Farooqi I.S., Fletcher P.C. Obesity and the brain: how convincing is the addiction model?. Nat Rev Neurosci 2012, 13:279-286.
83. Salamone JD, Correa M: Dopamine and food addiction: lexicon badly needed. Biol Psychiatry 2012, in press.
84. Berthoud H.R. Metabolic and hedonic drives in the neural control of appetite: who is the boss?. Curr Opin Neurobiol 2013, 21:888-896.
85. Treit D., Berridge K.C. A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm. Pharmacol Biochem Behav 1990, 37:451-456.
86. Levy D.J., Glimcher P.W. The root of all value: a neural common currency for choice. Curr Opin Neurobiol 2012, 22:1027-1038.
87. Rangel A., Camerer C., Montague P.R. A framework for studying the neurobiology of value-based decision making. Nat Rev Neurosci 2008, 9:545-556.