Clonal Expansion Analysis of Transposon Insertions by High-Throughput Sequencing Identifies Candidate Cancer Genes in a PiggyBac Mutagenesis Screen

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Friedel, Roland H ^a   Friedel, Caroline C ^b   Bonfert, Thomas ^b   Shi, Ruijin ^a   Rad, Roland ^c   Soriano, Philippe ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CANCER SCREENING; CLINICAL PROTOCOL; CLONAL VARIATION; CONTROLLED STUDY; DIACYLGLYCEROLKINASE DELTA GENE; GENE; GENE CONTROL; GENE FUNCTION; GENE IDENTIFICATION; GENE INSERTION; HIGH THROUGHPUT SEQUENCING; MALIGNANT NEOPLASTIC DISEASE; MASTERMIND LIKE 1 GENE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; ONCOGENE; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SOLID TUMOR; SOMATIC MUTATION; TRANSPOSON;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CLONAL EVOLUTION; DNA MUTATIONAL ANALYSIS; DNA TRANSPOSABLE ELEMENTS; GENETIC ASSOCIATION STUDIES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MICE; MICE, TRANSGENIC; MUTAGENESIS, INSERTIONAL; NEOPLASMS;

EID: 84881112695     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072338     Document Type: Article

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