Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma

Blood

Volumn 121, Issue 23, 2013, Pages 4718-4728

  Qu, Changju ^a   Liu, Yadong ^a   Kunkalla, Kranthi ^a   Singh, Rajesh R ^a   Blonska, Marzenna ^a   Lin, Xin ^a,b   Agarwal, Nitin Kumar ^a   Vega, Francisco ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARMA1 PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; PROTEIN BCL 10; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; BCL10 PROTEIN, HUMAN; CARD11 PROTEIN, HUMAN; CASPASE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CYTOKINE; G PROTEIN COUPLED RECEPTOR; GUANYLATE CYCLASE; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; LUCIFERASE; MALT1 PROTEIN, HUMAN; MESSENGER RNA; PROTEIN KINASE C; PROTEIN KINASE C BETA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; SMO PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; BONE MARROW STROMA CELL; CONTROLLED STUDY; DIFFUSE LARGE B CELL LYMPHOMA; DIFFUSE LARGE B-CELL LYMPHOMA CELL LINE; EMBRYO; GENE ACTIVATION; HEK293T CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SIGNAL TRANSDUCTION; ADULT; APOPTOSIS; CELL PROLIFERATION; DRUG ANTAGONISM; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENETICS; IMMUNOPRECIPITATION; LARGE CELL LYMPHOMA; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; APOPTOSIS; BLOTTING, WESTERN; CARD SIGNALING ADAPTOR PROTEINS; CASPASES; CELL PROLIFERATION; CYTOKINES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUANYLATE CYCLASE; HEDGEHOG PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; I-KAPPA B KINASE; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; LUCIFERASES; LYMPHOMA, LARGE B-CELL, DIFFUSE; NEOPLASM PROTEINS; NF-KAPPA B; PROTEIN KINASE C; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS; TNF RECEPTOR-ASSOCIATED FACTOR 6; TUMOR CELLS, CULTURED;

MLCS; MLOWN;

EID: 84881082520     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-470153     Document Type: Article

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