-
1
-
-
0025292712
-
Identification of mutations in the COL4A5 collagen gene in Alport syndrome
-
2349482 10.1126/science.2349482 1:CAS:528:DyaK3cXkslags7c%3D
-
Barker DF, Hostikka SL, Zhou J, Chow LT, Oliphant AR, Gerken SC, Gregory MC, Skolnick MH, Atkin CL, Tryggvason K (1990) Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science 248:1224-1227
-
(1990)
Science
, vol.248
, pp. 1224-1227
-
-
Barker, D.F.1
Hostikka, S.L.2
Zhou, J.3
Chow, L.T.4
Oliphant, A.R.5
Gerken, S.C.6
Gregory, M.C.7
Skolnick, M.H.8
Atkin, C.L.9
Tryggvason, K.10
-
2
-
-
0028939722
-
Autosomal recessive Alport syndrome: Immunohistochemical study of type IV collagen chain distribution
-
10.1038/ki.1995.163
-
Gubler MC, Knebelmann B, Beziau A, Broyer M, Pirson Y, Haddoum F, Kleppel MM, Antignac C (1995) Autosomal recessive Alport syndrome: Immunohistochemical study of type IV collagen chain distribution. Kidney Int 47:38-44
-
(1995)
Kidney Int
, vol.47
, pp. 38-44
-
-
Gubler, M.C.1
Knebelmann, B.2
Beziau, A.3
Broyer, M.4
Pirson, Y.5
Haddoum, F.6
Kleppel, M.M.7
Antignac, C.8
-
3
-
-
71049132261
-
Antifibrotic effects of aldosterone receptor blocker (Spironolactone) in patients with chronic kidney disease
-
19925284 10.3109/08860220903150312 1:CAS:528:DC%2BD1MXhsVClu7vJ
-
Guney I, Selcuk YN, Altintepe L, Atalay H, Başarali KM, Büyükbaş S (2009) Antifibrotic effects of aldosterone receptor blocker (Spironolactone) in patients with chronic kidney disease. Ren Fail 31:779-784
-
(2009)
Ren Fail
, vol.31
, pp. 779-784
-
-
Guney, I.1
Selcuk, Y.N.2
Altintepe, L.3
Atalay, H.4
Başarali, K.M.5
Büyükbaş, S.6
-
4
-
-
33746762170
-
Aldosterone promotes fibronectin production through a Smad2-dependent TGF-β1 pathway in mesangial cells
-
16876110 10.1016/j.bbrc.2006.07.057 1:CAS:528:DC%2BD28Xot1ajt7o%3D
-
Lai L, Chen J, Hao CM, Lin S, Gu Y (2006) Aldosterone promotes fibronectin production through a Smad2-dependent TGF-β1 pathway in mesangial cells. Biochem Biophys Res Commun 348:70-75
-
(2006)
Biochem Biophys Res Commun
, vol.348
, pp. 70-75
-
-
Lai, L.1
Chen, J.2
Hao, C.M.3
Lin, S.4
Gu, Y.5
-
6
-
-
0141566829
-
X-linked Alport syndrome: Natural history and genotype-phenotype correlations in girls and women belonging to 195 families: A "European Community Alport Syndrome Concerted Action" study
-
14514738 10.1097/01.ASN.0000090034.71205.74
-
Jais JP, Knebelmann B, Giartis I, De Marchi M, Rizzoni G, Renieri A, Weber M, Gross O, Netzer KO, Flinter F, Pirson Y, Dahan K, Wieslander J, Persson U, Tryggvason K, Martin P, Hertz JM, Schröder C, Sanak M, Carvalho MF, Saus J, Antignac C, Smeets H, Gubler MC (2003) X-linked Alport syndrome: Natural history and genotype-phenotype correlations in girls and women belonging to 195 families: A "European Community Alport Syndrome Concerted Action" study. J Am Soc Nephrol 14:2603-2610
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2603-2610
-
-
Jais, J.P.1
Knebelmann, B.2
Giartis, I.3
De Marchi, M.4
Rizzoni, G.5
Renieri, A.6
Weber, M.7
Gross, O.8
Netzer, K.O.9
Flinter, F.10
Pirson, Y.11
Dahan, K.12
Wieslander, J.13
Persson, U.14
Tryggvason, K.15
Martin, P.16
Hertz, J.M.17
Schröder, C.18
Sanak, M.19
Carvalho, M.F.20
Saus, J.21
Antignac, C.22
Smeets, H.23
Gubler, M.C.24
more..
-
7
-
-
69549089909
-
Treatment of Alport syndrome: Beyond animal models
-
19536083 10.1038/ki.2009.223 1:CAS:528:DC%2BD1MXhtVKgtLjN
-
Gross O, Kashtan CE (2009) Treatment of Alport syndrome: Beyond animal models. Kidney Int 76:599-603
-
(2009)
Kidney Int
, vol.76
, pp. 599-603
-
-
Gross, O.1
Kashtan, C.E.2
-
8
-
-
0347418134
-
Cyclosporine A slows the progressive renal disease of Alport syndrome (X-linked Hereditary Nephritis): Results from a canine model
-
12595505 10.1097/01.ASN.0000046964.15831.16 1:CAS:528: DC%2BD3sXht1Kjtr8%3D
-
Chen D, Jefferson B, Harvey SJ, Gartley CJ, Jacobs RM, Thorner PS (2003) Cyclosporine A slows the progressive renal disease of Alport syndrome (X-linked Hereditary Nephritis): Results from a canine model. J Am Soc Nephrol 14:690-698
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 690-698
-
-
Chen, D.1
Jefferson, B.2
Harvey, S.J.3
Gartley, C.J.4
Jacobs, R.M.5
Thorner, P.S.6
-
9
-
-
77954474511
-
Cyclosporine A treatment in patients with Alport syndrome: A single-center experience
-
20238228 10.1007/s00467-010-1484-3
-
Massella L, Onetti Muda A, Legato A, Di Zazzo G, Giannakakis K, Emma F (2010) Cyclosporine A treatment in patients with Alport syndrome: A single-center experience. Pediatr Nephrol 25:1269-1275
-
(2010)
Pediatr Nephrol
, vol.25
, pp. 1269-1275
-
-
Massella, L.1
Onetti Muda, A.2
Legato, A.3
Di Zazzo, G.4
Giannakakis, K.5
Emma, F.6
-
10
-
-
33846456191
-
Cyclosporine therapy in patients with Alport syndrome
-
17024394 10.1007/s00467-006-0227-y
-
Charbit M, Gubler MC, Dechaux M, Gagnadoux MF, Grünfeld JP, Niaudet P (2007) Cyclosporine therapy in patients with Alport syndrome. Pediatr Nephrol 22:57-63
-
(2007)
Pediatr Nephrol
, vol.22
, pp. 57-63
-
-
Charbit, M.1
Gubler, M.C.2
Dechaux, M.3
Gagnadoux, M.F.4
Grünfeld, J.P.5
Niaudet, P.6
-
11
-
-
1542330045
-
Enalapril in children with Alport syndrome
-
14745635 10.1007/s00467-003-1366-z
-
Proesmans W, Van Dyck M (2004) Enalapril in children with Alport syndrome. Pediatr Nephrol 19:271-275
-
(2004)
Pediatr Nephrol
, vol.19
, pp. 271-275
-
-
Proesmans, W.1
Van Dyck, M.2
-
12
-
-
79961074073
-
Efficacy and safety of losartan in children with Alport syndrome - results from a subgroup analysis of prospective, randomized, placebo- or amlodipine-controlled trial
-
21285125 10.1093/ndt/gfq797 1:CAS:528:DC%2BC3MXps1ykt70%3D
-
Webb NJ, Lam C, Shahinfar S (2011) Efficacy and safety of losartan in children with Alport syndrome - results from a subgroup analysis of prospective, randomized, placebo- or amlodipine-controlled trial. Nephrol Dial Transplant 26:2521-2526
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 2521-2526
-
-
Webb, N.J.1
Lam, C.2
Shahinfar, S.3
-
13
-
-
84857109752
-
Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy
-
22166847 10.1038/ki.2011.407 1:CAS:528:DC%2BC38XisFWrs78%3D
-
Gross O, Licht C, Anders HJ (2012) Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy. Kidney Int 81:494-501
-
(2012)
Kidney Int
, vol.81
, pp. 494-501
-
-
Gross, O.1
Licht, C.2
Anders, H.J.3
-
14
-
-
0037431774
-
Combination treatment of angiotensin II receptor blocker and angiotensin-converting-enzyme inhibitor in non diabetic renal disease
-
12531578 10.1016/S0140-6736(03)12229-5 1:CAS:528:DC%2BD3sXisl2rtQ%3D%3D
-
Nakao N, Yoshimura A (2003) Combination treatment of angiotensin II receptor blocker and angiotensin-converting-enzyme inhibitor in non diabetic renal disease. Lancet 361:117-124
-
(2003)
Lancet
, vol.361
, pp. 117-124
-
-
Nakao, N.1
Yoshimura, A.2
-
15
-
-
40149090641
-
Effect of Renin-Angiotensin-Aldosterone system triple blockade on non-diabetic renal disease: Addition of aldosterone blocker, Spironolactone, to combination treatment with an angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker
-
18360019 10.1291/hypres.31.59 1:CAS:528:DC%2BD1cXltl2ntbo%3D
-
Furumatsu Y, Nagasawa Y, Tomida K, Mikami S, Kaneko T, Okada N, Tsubakihara Y, Imai E, Shoji T (2008) Effect of Renin-Angiotensin-Aldosterone system triple blockade on non-diabetic renal disease: Addition of aldosterone blocker, Spironolactone, to combination treatment with an angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker. Hypertens Res 31:59-67
-
(2008)
Hypertens Res
, vol.31
, pp. 59-67
-
-
Furumatsu, Y.1
Nagasawa, Y.2
Tomida, K.3
Mikami, S.4
Kaneko, T.5
Okada, N.6
Tsubakihara, Y.7
Imai, E.8
Shoji, T.9
-
16
-
-
77958533631
-
Addition of spironolactone to dual blockade of renina angiotensin system dramatically reduces severe proteinuria in renal transplant patients: An uncontrolled pilot study at 6 months
-
20970564 10.1016/j.transproceed.2010.08.024
-
González Monte E, Andrés A, Polanco N, Toribio ML, Santana R, Gutiérrez Martínez E, González J, Ramírez E, Hernández A, Morales E, Praga M, Morales JM (2010) Addition of spironolactone to dual blockade of renina angiotensin system dramatically reduces severe proteinuria in renal transplant patients: An uncontrolled pilot study at 6 months. Transplant Proc 42:2899-2901
-
(2010)
Transplant Proc
, vol.42
, pp. 2899-2901
-
-
González Monte, E.1
Andrés, A.2
Polanco, N.3
Toribio, M.L.4
Santana, R.5
Gutiérrez Martínez, E.6
González, J.7
Ramírez, E.8
Hernández, A.9
Morales, E.10
Praga, M.11
Morales, J.M.12
-
17
-
-
33750993170
-
The effect of aldosterone blockade in patients with Alport syndrome
-
17039334 10.1007/s00467-006-0270-8
-
Kaito H, Nozu K, Iijima K, Nakanishi K, Yoshiya K, Kanada K, Przybyslaw Krol R, Yoshikawa N, Matsuo M (2006) The effect of aldosterone blockade in patients with Alport syndrome. Pediatr Nephrol 21:1824-1829
-
(2006)
Pediatr Nephrol
, vol.21
, pp. 1824-1829
-
-
Kaito, H.1
Nozu, K.2
Iijima, K.3
Nakanishi, K.4
Yoshiya, K.5
Kanada, K.6
Przybyslaw Krol, R.7
Yoshikawa, N.8
Matsuo, M.9
-
18
-
-
84870405692
-
Clinical practice recommendations for the treatment of Alport syndrome: A statement of the Alport Syndrome Research Collaborative
-
22461141 10.1007/s00467-012-2138-4
-
Kashtan CE, Ding J, Gregory M, Gross O, Heidet L, Knebelmann B, Rheault M, Licht C (2013) Clinical practice recommendations for the treatment of Alport syndrome: A statement of the Alport Syndrome Research Collaborative. Pediatr Nephrol 28:5-11
-
(2013)
Pediatr Nephrol
, vol.28
, pp. 5-11
-
-
Kashtan, C.E.1
Ding, J.2
Gregory, M.3
Gross, O.4
Heidet, L.5
Knebelmann, B.6
Rheault, M.7
Licht, C.8
-
19
-
-
0023179130
-
The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents
-
3588043 1:STN:280:DyaL2s3jtVGrsg%3D%3D
-
Schwartz GJ, Brion LP, Spitzer A (1987) The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am 34:571-590
-
(1987)
Pediatr Clin North Am
, vol.34
, pp. 571-590
-
-
Schwartz, G.J.1
Brion, L.P.2
Spitzer, A.3
-
20
-
-
33845302661
-
Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease
-
17035949 1:CAS:528:DC%2BD28Xht1Kju7bL
-
Bianchi S, Bigazzi R, Campese VM (2006) Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. Kidney Int 70:2116-2123
-
(2006)
Kidney Int
, vol.70
, pp. 2116-2123
-
-
Bianchi, S.1
Bigazzi, R.2
Campese, V.M.3
-
21
-
-
0037670191
-
Effect of losartan and amlodipine on proteinuria and transforming growth factor-β1 in patients with IgA nephropathy
-
12748343 10.1093/ndt/gfg090 1:CAS:528:DC%2BD3sXjvFCmtLs%3D
-
Park HC, Xu ZG, Choi S, Goo YS, Kang SW, Choi KH, Ha SK, Lee HY, Han DS (2003) Effect of losartan and amlodipine on proteinuria and transforming growth factor-β1 in patients with IgA nephropathy. Nephrol Dial Transplant 18:1115-1121
-
(2003)
Nephrol Dial Transplant
, vol.18
, pp. 1115-1121
-
-
Park, H.C.1
Xu, Z.G.2
Choi, S.3
Goo, Y.S.4
Kang, S.W.5
Choi, K.H.6
Ha, S.K.7
Lee, H.Y.8
Han, D.S.9
-
22
-
-
0029550256
-
Aldosterone escape during ACE inhibitor therapy in chronic heart failure
-
8682054 10.1093/eurheartj/16.suppl-N.103 1:CAS:528:DyaK28XitlGlsrY%3D
-
Struthers AD (1995) Aldosterone escape during ACE inhibitor therapy in chronic heart failure. Eur Heart J 16:103-106
-
(1995)
Eur Heart J
, vol.16
, pp. 103-106
-
-
Struthers, A.D.1
-
23
-
-
31544466805
-
Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effects of aldosterone blockade
-
16397374 10.1254/jphs.FMJ05003X3 1:CAS:528:DC%2BD28Xht1SrtL4%3D
-
Nishiyama A, Abe Y (2006) Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effects of aldosterone blockade. J Pharmacol Sci 100:9-16
-
(2006)
J Pharmacol Sci
, vol.100
, pp. 9-16
-
-
Nishiyama, A.1
Abe, Y.2
-
24
-
-
33745059679
-
Accurate measurement and clinical significance of urinary transforming growth factor-beta1
-
16679757 10.1159/000093178 1:CAS:528:DC%2BD28XltFWltbk%3D
-
Tsakas S, Goumenos DS (2006) Accurate measurement and clinical significance of urinary transforming growth factor-beta1. Am J Nephrol 26:186-193
-
(2006)
Am J Nephrol
, vol.26
, pp. 186-193
-
-
Tsakas, S.1
Goumenos, D.S.2
-
25
-
-
0037670191
-
Effect of losartan and amlodipine on proteinuria and transforming growth factor-β1 in patients with IgA nephropathy
-
10.1093/ndt/gfg090
-
Cheon Park H, Gao Xu Z, Choi S, Young SG, Wook Kang S, Hun Choi K, Kyu Ha S, Lee Y, Suk Han D (2003) Effect of losartan and amlodipine on proteinuria and transforming growth factor-β1 in patients with IgA nephropathy. Nephrol Dial Transplant 18:1115-1121
-
(2003)
Nephrol Dial Transplant
, vol.18
, pp. 1115-1121
-
-
Cheon Park, H.1
Gao Xu, Z.2
Choi, S.3
Young, S.G.4
Wook Kang, S.5
Hun Choi, K.6
Kyu Ha, S.7
Lee, Y.8
Suk Han, D.9
-
27
-
-
0033623532
-
Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy
-
11073824 10.1016/S0002-9440(10)64802-X 1:CAS:528:DC%2BD3cXosFyhs7g%3D
-
Cosgrove D, Rodgers K, Meehan D, Miller C, Bovard K, Gilroy A, Gardner H, Kotelianski V, Gotwals P, Amatucci A, Kalluri R (2000) Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am J Pathol 157:1649-1659
-
(2000)
Am J Pathol
, vol.157
, pp. 1649-1659
-
-
Cosgrove, D.1
Rodgers, K.2
Meehan, D.3
Miller, C.4
Bovard, K.5
Gilroy, A.6
Gardner, H.7
Kotelianski, V.8
Gotwals, P.9
Amatucci, A.10
Kalluri, R.11
-
28
-
-
3342886011
-
Angiotensin converting enzyme inhibitor therapy in children with Alport syndrome: Effect on urinary albumin, TGF-β, and nitrite excretion
-
11869456 10.1186/1471-2369-3-2
-
Adler L, Mathew R, Futterweit S, Frank R, Gauthier BG, Kashtan CE, Trachtman H (2002) Angiotensin converting enzyme inhibitor therapy in children with Alport syndrome: Effect on urinary albumin, TGF-β, and nitrite excretion. BMC Nephrol 3:2-7
-
(2002)
BMC Nephrol
, vol.3
, pp. 2-7
-
-
Adler, L.1
Mathew, R.2
Futterweit, S.3
Frank, R.4
Gauthier, B.G.5
Kashtan, C.E.6
Trachtman, H.7
-
29
-
-
34548029979
-
New insights into the pathophysiology of cyclosporine nephrotoxicity: A role of aldosterone
-
17429034 10.1152/ajprenal.00072.2007 1:CAS:528:DC%2BD2sXovVygsb0%3D
-
Bobadilla NA, Gamba G (2007) New insights into the pathophysiology of cyclosporine nephrotoxicity: A role of aldosterone. Am J Physiol Renal Physiol 293:F2-F9
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Bobadilla, N.A.1
Gamba, G.2
-
30
-
-
84863983649
-
Glomerular pathology in Alport syndrome: A molecular prospective
-
21455721 10.1007/s00467-011-1868-z
-
Cosgrove D (2012) Glomerular pathology in Alport syndrome: A molecular prospective. Pediatr Nephrol 27:885-890
-
(2012)
Pediatr Nephrol
, vol.27
, pp. 885-890
-
-
Cosgrove, D.1
|