Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells

Cell Death and Disease

Volumn 4, Issue 7, 2013, Pages

  Yang, X ^a   Liu, S ^a   Yan, Q ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Epithelial mesenchymal transition; Fucosyltransferase IV; NF B; PI3K Akt

Indexed keywords

FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE IV; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE CONTROL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FUCOSYLTRANSFERASES; HUMANS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84881061331     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.241     Document Type: Article

References (57)

1. Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 2009; 119: 1417-1419.
2. Zeisberg M, Neilson EG. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 2009; 119: 1429-1437.
3. Moreno-Bueno G, Portillo F, Cano A. Transcriptional regulation of cell polarity in EMT and cancer. Oncogene 2008; 27: 6958-6969.
4. Jing Y, Han Z, Zhang S, Liu Y, Wei L. Epithelial-mesenchymal transition in tumor microenvironment. Cell Biosci 2011; 1: 29.
5. Huber MA, Azoitei N, Baumann B, Grunert S, Sommer A, Pehamberger H et al. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 2004; 114: 569-581.
6. Iwatsuki M, Mimori K, Yokobori T, Ishi H, Beppu T, Nakamori S et al. Epithelial-mesenchymal transition in cancer development and its clinical significance. Cancer Sci 2011; 101: 293-299.
7. Peinado H, Portillo F, Cano A. Transcriptional regulation of cadherins during development and carcinogenesis. Int J Dev Biol 2004; 48: 365-375.
8. Min C, Eddy SF, Sherr DH, Sonenshein GE. NF-kappaB and epithelial to mesenchymal transition of cancer. J Cell Biochem 2008; 104: 733-744.
9. Julien S, Puig I, Caretti E, Bonaventure J, Nelles L, van Roy F et al. Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition. Oncogene 2007; 26: 7445-7456.
10. Martin TA, Goyal A, Watkins G, Jiang WG. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann Surg Oncol 2005; 12: 488-496.
11. Parker BS, Argani P, Cook BP, Liangfeng H, Chartrand SD, Zhang M et al. Alterations in vascular gene expression in invasive breast carcinoma. Cancer Res 2004; 64: 7857-7866.
12. De Craene B, van Roy F, Berx G. Unraveling signalling cascades for the Snail family of transcription factors. Cell Signal 2005; 17: 535-547.
13. Hakomori S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci USA 2002; 99: 10231-10233.
14. Cao Y, Merling A, Karsten U, Schwartz-Albiez R. The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34\+ hematopoietic progenitors but absent on mature lymphocytes. Glycobiology 2001; 11: 677-683.
15. Wang H, Wang QY, Zhang Y, Shen ZH, Chen HL. Alpha1,3 Fucosyltransferase- VII modifies the susceptibility of apoptosis induced by ultraviolet and retinoic acid in human hepatocarcinoma cells. Glycoconj J 2007; 24: 207-220.
16. Ciolczyk-Wierzbicka D, Bodzioch M, Gil D, Zmudzinska D, Dembinska-Kiec A, Laidler P. Expression of fucosyltransferases contributes to melanoma invasive phenotype. Med Chem 2007; 3: 418-424.
17. Weston BW, Nair RP, Larsen RD, Lowe JB. Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities. J Biol Chem 1992; 267: 4152-4160.
18. Weston BW, Smith PL, Kelly RJ, Lowe JB. Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. J Biol Chem 1992; 267: 24575-24584.
19. Sasaki K, Kurata K, Funayama K, Nagata M, Watanabe E, Ohta S et al. Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. J Biol Chem 1994; 269: 14730-14737.
20. Kudo T, Ikehara Y, Togayachi A, Kaneko M, Hiraga T, Sasaki K et al. Expression cloning and characterization of a novel murine alpha1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. J Biol Chem 1998; 273: 26729-26738.
21. Escrevente C, Machado E, Brito C, Reis CA, Stoeck A, Runz S et al. Different expression levels of alpha3/4 fucosyltransferases and Lewis determinants in ovarian carcinoma tissues and cell lines. Int J Oncol 2006; 29: 557-566.
22. Taniguchi A, Suga R, Matsumoto K. Expression and transcriptional regulation of the human alpha1, 3-fucosyltransferase 4 (FUT4) gene in myeloid and colon adenocarcinoma cell lines. Biochem Biophys Res Commun 2000; 273: 370-376.
23. Wang H, Ge CH, Kong Y, Xin Y, Zhu ZM. Ovary Hormonal Control of Le(y) Oligosaccharide Expression during Peri-implantation of Mouse Endometrium. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2001; 33: 542-546.
24. Yang X, Zhang Z, Jia S, Liu Y, Wang X, Yan Q. Overexpression of fucosyltransferase IV in A431 cell line increases cell proliferation. Int J Biochem Cell Biol 2007; 39: 1722-1730.
25. Yang XS, Liu SA, Liu JW, Yan Q. Fucosyltransferase IV enhances expression of MMP-12 stimulated by EGF via the ERK1/2, p38 and NF-kappaB pathways in A431Cells. Asian Pac J Cancer Prev 2012; 13: 1657-1662.
26. Guo BH, Feng Y, Zhang R, Xu LH, Li MZ, Kung HF et al. Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer. Mol Cancer 2011; 10: 10.
27. Lee YJ, Han HJ. Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3{beta}, Snail1, and {beta}-catenin in renal proximal tubule cells. Am J Physiol Renal Physiol 2009; 298: F1263-F1275.
28. Xiangming X, Yun Q, Guoliang Z, Jianjiang L, Lisong T. Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway. Braz J Med Biol Res 2011; 44: 634-641.
29. Xu Y, Lee SH, Kim HS, Kim NH, Piao S, Park SH et al. Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail. Oncogene 2010; 29: 3124-3133.
30. Li YC, Gao WJ. GSK-3beta activity and hyperdopamine-dependent behaviors. Neurosci Biobehav Rev 2011; 35: 645-654.
31. Mishra R. Glycogen synthase kinase 3 beta: can it be a target for oral cancer. Mol Cancer 2010; 9: 144.
32. Shih JY, Yang PC. The EMT regulator slug and lung carcinogenesis. Carcinogenesis 2011; 32: 1299-1304.
33. Bachelder RE, Yoon SO, Franci C, de Herreros AG, Mercurio AM. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelialmesenchymal transition. J Cell Biol 2005; 168: 29-33.
34. He S, Zhu W, Zhou Y, Huang Y, Ou Y, Li Y et al. Transcriptional and post-transcriptional down-regulation of cyclin D1 contributes to C6 glioma cell differentiation induced by forskolin. J Cell Biochem 2011; 112: 2241-2249.
35. Krzeslak A, Jozwiak P, Lipinska A. Down-regulation of beta-N-acetyl-D-glucosaminidase increases Akt1 activity in thyroid anaplastic cancer cells. Oncol Rep 2011; 26: 743-749.
36. Parrales A, Lopez E, Lopez-Colome AM. Thrombin activation of PI3K/PDK1/Akt signaling promotes cyclin D1 upregulation and RPE cell proliferation. Biochim Biophys Acta 2011; 1813: 1758-1766.
37. Shimura T, Kakuda S, Ochiai Y, Kuwahara Y, Takai Y, Fukumoto M. Targeting the AKT/GSK3beta/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy. Int J Radiat Oncol Biol Phys 2011; 80: 540-548.
38. Liang J, Slingerland JM. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2003; 2: 339-345.
39. Takahashi-Yanaga F, Sasaguri T. GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy. Cell Signal 2008; 20: 581-589.
40. Li QQ, Chen ZQ, Cao XX, Xu JD, Xu JW, Chen YY et al. Involvement of NF-kappaB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial-mesenchymal transition of breast cancer cells. Cell Death Differ 2011; 18: 16-25.
41. Sethi S, Sarkar FH, Ahmed Q, Bandyopadhyay S, Nahleh ZA, Semaan A et al. Molecular markers of epithelial-to-mesenchymal transition are associated with tumor aggressiveness in breast carcinoma. Transl Oncol 2011; 4: 222-226.
42. Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275-292.
43. Li M, Song L, Qin X. Glycan changes: cancer metastasis and anti-cancer vaccines. J Biosci 2010; 35: 665-673.
44. Rambaruth ND, Dwek MV. Cell surface glycan-lectin interactions in tumor metastasis. Acta Histochem 2011; 113: 591-600.
45. Yang XS, Liu S, Liu YJ, Liu JW, Liu TJ, Wang XQ et al. Overexpression of fucosyltransferase IV promotes A431 cell proliferation through activating MAPK and PI3K/Akt signaling pathways. J Cell Physiol 2010; 225: 612-619.
46. Yang X, Liu Y, Liu J, Wang X, Yan Q. Cyclophosphamide-induced apoptosis in A431 cells is inhibited by fucosyltransferase IV. J Cell Biochem 2011; 112: 1376-1383.
47. Hong KO, Kim JH, Hong JS, Yoon HJ, Lee JI, Hong SP et al. Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells. J Exp Clin Cancer Res 2009; 28: 28.
48. Sineva GS, Pospelov VA. Inhibition of GSK3beta enhances both adhesive and signalling activities of beta-catenin in mouse embryonic stem cells. Biol Cell 2010; 102: 549-560.
49. De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 2013; 13: 97-110.
50. Moreno-Bueno G, Cubillo E, Sarrio D, Peinado H, Rodriguez-Pinilla SM, Villa S et al. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res 2006; 66: 9543-9556.
51. Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 2003; 116(Pt 3): 499-511.
52. Soini Y, Tuhkanen H, Sironen R, Virtanen I, Kataja V, Auvinen P et al. Transcription factors zeb1, twist and snai1 in breast carcinoma. BMC Cancer 2011; 11: 73.
53. Elloul S, Elstrand MB, Nesland JM, Trope CG, Kvalheim G, Goldberg I et al. Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 2005; 103: 1631-1643.
54. Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero CP, Sterner CJ et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 2005; 8: 197-209.
55. Djamali A, Vidyasagar A, Yagci G, Huang LJ, Reese S. Mycophenolic acid may delay allograft fibrosis by inhibiting transforming growth factor-beta1-induced activation of Nox-2 through the nuclear factor-kappaB pathway. Transplantation 2010; 90: 387-393.
56. Maier HJ, Schmidt-Strassburger U, Huber MA, Wiedemann EM, Beug H, Wirth T. NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett 2010; 295: 214-228.
57. Orlowski RZ, Baldwin AS Jr. NF-kappaB as a therapeutic target in cancer. Trends Mol Med 2002; 8: 385-389.