Decreased expression of insulin and increased expression of pancreatic transcription factor PDX-1 in islets in patients with liver cirrhosis: A comparative investigation using human autopsy specimens

Journal of Gastroenterology

Volumn 48, Issue 2, 2013, Pages 277-285

  Sakata, Masahiro ^a   Kawahara, Akihiko ^b   Kawaguchi, Takumi ^a   Akiba, Jun ^a,b   Taira, Tomoki ^b   Taniguchi, Eitaro ^a   Abe, Mitsuhiko ^a   Koga, Hironori ^a   Kage, Masayoshi ^b   Sata, Michio ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KURUME UNIVERSITY HOSPITAL   (Japan)

Author keywords

Diabetes; Insulin; Islet; Liver cirrhosis; Pancreatic duodenal homeobox 1

Indexed keywords

C PEPTIDE; CYCLINE; FATTY ACID; GLUCAGON; HEMOGLOBIN A1C; INSULIN; KI 67 ANTIGEN; SOMATOSTATIN; TRANSCRIPTION FACTOR PDX 1; HOMEODOMAIN PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

AGED; ARTICLE; AUTOPSY; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOCRINE CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; LIVER CIRRHOSIS; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; BIOPSY; HYPERTROPHY; METABOLISM; MIDDLE AGED; PANCREAS ISLET; PATHOLOGY;

AGED; BIOPSY; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCAGON; HOMEODOMAIN PROTEINS; HUMANS; HYPERTROPHY; INSULIN; ISLETS OF LANGERHANS; KI-67 ANTIGEN; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PROLIFERATING CELL NUCLEAR ANTIGEN; RETROSPECTIVE STUDIES; SOMATOSTATIN; TRANS-ACTIVATORS;

MLCS; MLOWN;

EID: 84880999262     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0633-9     Document Type: Article

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