Licochalcone a enhances geldanamycin-induced apoptosis through reactive oxygen species-mediated caspase activation

Pharmacology

Volumn 92, Issue 1-2, 2013, Pages 49-59

  Kim, Yun Jeong ^a   Jung, Eun Byul ^a   Myung, Soon Chul ^b   Kim, Wonyong ^a   Lee, Chung Soo ^a  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

Apoptosis related proteins; Epithelial ovarian adenocarcinoma cell lines; Geldanamycin; Licochalcone A; Reactive oxygen species

Indexed keywords

CASPASE; CYTOCHROME C; GELDANAMYCIN; GLUTATHIONE; LICOCHALCONE A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; REACTIVE OXYGEN METABOLITE; ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOSPORIN A;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL LEVEL; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONTENT; PROTEIN DEPLETION; PROTEIN SECRETION; TUMOR CELL LINE; CARCINOMA CELL LINE; CELL DEATH; CELL VIABILITY; DEPLETION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MITOCHONDRIAL MEMBRANE; MTT ASSAY; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BENZOQUINONES; CASPASES; CELL LINE, TUMOR; CHALCONES; CYTOCHROMES C; DRUG SYNERGISM; GLUTATHIONE; HUMANS; LACTAMS, MACROCYCLIC; MEMBRANE POTENTIAL, MITOCHONDRIAL; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES;

EID: 84880974487     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000351846     Document Type: Article

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