Engineering the meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by site saturation mutagenesis for d-phenylalanine synthesis

Applied and Environmental Microbiology

Volumn 79, Issue 16, 2013, Pages 5078-5081

  Gao, Xiuzhen ^a,b   Huang, Fang ^b   Feng, Jinhui ^a   Chen, Xi ^a   Zhang, Hailing ^a   Wang, Zhixiang ^b   Wu, Qiaqing ^a   Zhu, Dunming ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

D-PHENYLALANINE; FOUR AMINO ACIDS; SATURATION MUTAGENESIS; SINGLE MUTANT; SPECIFIC ACTIVITY; SUBSTRATE BINDING; SYMBIOBACTERIUM THERMOPHILUM; WILD-TYPE ENZYMES;

AMINO ACIDS;

MUTAGENESIS;

AMINO ACID; DIAMINOPIMELATE DEHYDROGENASE; OXIDOREDUCTASE; PHENYLALANINE;

AMINO ACID; ENZYME ACTIVITY; MICROBIAL ACTIVITY; MICROBIAL COMMUNITY; MUTAGENICITY; SATURATION; SUBSTRATE;

ARTICLE; BACTERIUM; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; SITE DIRECTED MUTAGENESIS;

AMINO ACID OXIDOREDUCTASES; AMINO ACIDS; BACTERIA; BINDING SITES; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; SUBSTRATE SPECIFICITY;

EID: 84880973674     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01049-13     Document Type: Article

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