High in vitro immune reactivity to Escherichia coli in neuromyelitis optica patients is correlated with both neurological disabilities and elevated plasma lipopolysaccharide levels

Human Immunology

Volumn 74, Issue 9, 2013, Pages 1080-1087

  Barros, Priscila O ^a   Linhares, Ulisses C ^a   Teixeira, Bruna ^a   Kasahara, Taissa M ^a   Ferreira, Thais B ^a   Alvarenga, Regina ^a   Hygino, Joana ^a   Silva Filho, Renato G ^a   Bittencourt, Vera Carolina B ^a   Andrade, Regis M ^b   Andrade, Arnaldo F ^a   Bento, Cleonice A M ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF THE STATE OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ADULT; ARTICLE; CANDIDA ALBICANS; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENVIRONMENTAL FACTOR; ESCHERICHIA COLI; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOREACTIVITY; IN VITRO STUDY; INFORMED CONSENT; LEUKOCYTE; MALE; MYELOOPTIC NEUROPATHY; NEUROLOGIC DISEASE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ADULT; ANTIGENS, BACTERIAL; CANDIDA ALBICANS; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; ESCHERICHIA COLI; FEMALE; HUMANS; IMMUNITY, CELLULAR; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; NEUROMYELITIS OPTICA; STAPHYLOCOCCUS AUREUS; TH17 CELLS; YOUNG ADULT;

EID: 84880937518     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2013.06.016     Document Type: Article

References (38)

1. Wingerchuk D., Lennon V., Lucchinetti C., Pittock S., Weinchenker B. The spectrum of neuromyelitis optica. Lancet Neurol 2007, 6:805-815.
2. Kira J., Yamasaki K., Horiuchi I., Ohyagi Y., Taniwaki T., Kawano Y. Changes in the clinical phenotypes of multiple sclerosis during the past 50 years in Japan. J Neurol Sci 1999, 166:53-57.
3. Cabrera-Gomez J.A., Kurtzke J.F., Gonzalez-Queved A., Lara-Rodriguez R. An epidemiological study of neuromyelitis optica in Cuba. J Neurol 2009, 256:35-44.
4. Papais-Alvarenga R.M., Miranda-Santos C.M., Puccioni-Sohler M., de Almeida A.M., Oliveira S., Basílio de Oliveira C.A., et al. Optic neuromyelitis syndrome in Brazilian patients. J Neurol Neurosurg Psychiatry 2002, 73:429-435.
5. Argyriou A.A., Makris N. Neuromyelitis optica: a distinct demyelinating disease of the central nervous system. Acta Neurol Scand 2008, 118:209-217.
6. Lucchinetti C.F., Mandler R.N., McGavern D., Bruck W., Gleich G., Ransohoff R.M., et al. A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain 2002, 125:1450-1461.
7. Kira J.I. Neuromyelitis optica and opticospinal multiple sclerosis: mechanisms and pathogenesis. Pathophysiology 2011, 18:69-79.
8. Lennon V.A., Kryzer T.J., Pittock S.J., Verkman A.S., Hinson S.R. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005, 202:473-477.
9. Takahashi T., Fujihara K., Nakashima I., Misu T., Miyazawa I., Nakamura M., et al. Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. Brain 2007, 130(5):1235-1243.
10. Varrin-Doyer M., Spencer C.M., Schulze-Topphoff U., Nelson P.A., Stroud R.M., Cree B.A.C., et al. Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Ann Neurol 2012, 72:53-64.
11. Bennett J.L., Lam C., Kalluri S.R., et al. Intrathecal pathogenic antiaquaporin-4 antibodies in early neuromyelitis optica. Ann Neurol 2009, 66:617-629.
12. Bradl M., Misu T., Takahashi T., et al. Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo. Ann Neurol 2009, 66:630-643.
13. Vaknin-Dembinsky A., Brill L., Kassis I., Petrou P., Ovadia H., Ben-Hur T., et al. T-cell reactivity against AQP4 in neuromyelitis optica. Neurology 2012, 79(9):945-946.
14. Ishizu T., Osoegawa M., Mei F.-J., Kikuchi H., Tanaka M., Takakura Y., et al. Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. Brain 2005, 128:988-1002.
15. + T cells is directly associated with neurological disability in neuromyelitis optica patients. J Clin Immunol 2012, 33:179-189.
16. Uzawa A., Mori M., Arai K., Sato Y., Hayakawa S., Masuda S., et al. Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6. Multiple Sclerosis 2010, 16:1443-1452.
17. Caldas C.A.M., Carvalh J.F. The role of environmental factors in the pathogenesis of non-organ-specific autoimmune diseases. Best Pract Res Clin Rheumatol 2012, 26:5-11.
18. Persson G.R. Rheumatoid arthritis and periodontitis- inflammatory and infectious connections. Review of the literature. J Oral Microbiol 2012, 4:11829.
19. Wingerchuk D.M., Lennon V.A., Pittock S.J., Lucchinetti C.F., Weinshenker B.G. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006, 66:1485-1489.
20. Brenchley J.M., Price D.A., Schacker T.W., Asher T.E., Silvestri G., Rao S., et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006, 12:1365-1371.
21. Jin B., Sun T., Yu X.-H., Yang Y.-X., Yeo A.E.T. The effects of TLR activation on T-cell development and differentiation. Clin Dev Immunol 2012, 836485:32.
22. Wang H.H., Dai Y.Q., Qiu W., Lu Z.Q., Peng F.H., Wang Y.G., et al. Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse. J Clin Neurosci 2011, 18:1313-1317.
23. Evans H.G., Suddason T., Jackson I., Taams L.S., Lord G.M. Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes. Proc Natl Acad Sci USA 2007, 104:17034-17039.
24. Mills K.H.G. TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol 2011, 11:807-825.
25. Lindstrom M., Heikinheimo A., Lahti P., Korkeala H. Novel insights into the epidemiology of Clostridium perfringens type A food poisoning. Food Microbiol 2011, 28:192-198.
26. Syrbe U., Scheer R., Wu P., Sieper J. Differential synovial Th1 cell reactivity towards Escherichia coli antigens in patients with ankylosing spondylitis and rheumatoid arthritis. Arch Dis Child 2012, 71:1573-1576.
27. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
28. Schrijver I.A., van Meurs M., Melief M.J., Wim Ang C., Buljevac D., Ravid R., et al. Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis. Brain 2011, 124:1544-1554.
29. Bsibsi M., Ravid R., Gveric D., Noort J.M. Broad expression of Toll-like receptors in the human central nervous system. J Neuropathol Exp Neurol 2002, 61:1013-1021.
30. Hansen B.S., Hussain R.Z., Lovett-Racke A.E., Thomas J.A., Racke M.K. Multiple Toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity. J Neuroimmunol 2006, 172:94-103.
31. Komai-Koma M., Jones L., Ogg G.S., Xu D., Liew F.Y. TLR2 is expressed activated T cells as a costimulatory receptor. Proc Natl Acad Sci USA 2004, 101:3029-3034.
32. Schnare M., Barton G.M., Holt A.C., Takeda K., Akira S., Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001, 2:947-950.
33. Mansson A., Adner M., Cardell L.O. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res 2006, 7:36-45.
34. Loser K., Beisser S. Regulatory T cells: banned cells for decades. J Invest Dermatol 2012, 132:864-871.
35. Pasare C., Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003, 299:1033-1036.
36. Kabelitz D. Expression and function of Toll-like receptors in T lymphocytes. Curr Opin Immunol 2007, 19:39-45.
37. Peng G., Guo Z., Kiniwa Y., Guo Z., Kiniwa Y., Voo K.S., et al. Immunology: Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 2005, 309:1380-1384.
38. Gareau M.G., Silva M.A., Perdue M.H. Pathophysiological mechanisms of stress-induced intestinal damage. Curr Mol Med 2008, 8:274-281.