Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S

Neuroscience

Volumn 248, Issue , 2013, Pages 479-487

  Neve, K A ^a   Ford, C P ^a,c   Buck, D C ^a   Grandy, D K ^a   Neve, R L ^b   Phillips, T J ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

D2 receptor null mutant mouse; Dopamine D2 receptor; Methamphetamine; Potassium channel

Indexed keywords

AUTORECEPTOR; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; HERPESVIRUS VECTOR; METHAMPHETAMINE; PARVOVIRUS VECTOR; POSTSYNAPTIC RECEPTOR; QUINPIROLE; SULPIRIDE; DOPAMINE D2L RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL BEHAVIOR; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; FEMALE; FOREBRAIN; GENE DELETION; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOUSE; NERVE CELL; NERVE STIMULATION; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; RESPONSE TIME; SEX DIFFERENCE; SUBSTANTIA NIGRA; AGONISTS; ANIMAL; CYTOLOGY; DEFICIENCY; DOPAMINERGIC NERVE CELL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE TRANSFER; METABOLISM;

ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE AGONISTS; DOPAMINERGIC NEURONS; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; LOCOMOTION; MALE; METHAMPHETAMINE; MICE; MICE, KNOCKOUT; NEURONS; NUCLEUS ACCUMBENS; RECEPTORS, DOPAMINE D2;

EID: 84880936058     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.06.035     Document Type: Article

References (33)

1. Baik J.H., Picetti R., Saiardi A., Thiriet G., Dierich A., Depaulis A., Le Meur M., Borrelli E. Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors. Nature 1995, 377:424-428.
2. 3 dopamine receptors in vivo. J Neurosci 2007, 27:881-885.
3. Beckstead M.J., Phillips T.J. Mice selectively bred for high- or low-alcohol-induced locomotion exhibit differences in dopamine neuron function. J Pharmacol Exp Ther 2009, 329:342-349.
4. Beckstead M.J., Grandy D.K., Wickman K., Williams J.T. Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. Neuron 2004, 42:939-946.
5. Centonze D., Grande C., Usiello A., Gubellini P., Erbs E., Martin A.B., Pisani A., Tognazzi N., Bernardi G., Moratalla R., Borrelli E., Calabresi P. Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons. J Neurosci 2003, 23:6245.
6. Centonze D., Usiello A., Costa C., Picconi B., Erbs E., Bernardi G., Borrelli E., Calabresi P. Chronic haloperidol promotes corticostriatal long-term potentiation by targeting dopamine D2L receptors. J Neurosci 2004, 24:8214-8222.
7. 2 receptor: two molecular forms generated by alternative splicing. EMBO J 1989, 8:4025-4034.
8. Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci U S A 1988, 85:5274-5278.
9. Ford C.P., Mark G.P., Williams J.T. Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J Neurosci 2006, 26:2788-2797.
10. Ford C.P., Phillips P.E., Williams J.T. The time course of dopamine transmission in the ventral tegmental area. J Neurosci 2009, 29:13344-13352.
11. Fulton S., Thibault D., Mendez J.A., Lahaie N., Tirotta E., Borrelli E., Bouvier M., Tempel B.L., Trudeau L.E. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. J Biol Chem 2011, 286:9360-9372.
12. 2 dopamine receptor isoforms. Nature 1989, 342:923-926.
13. 2 dopamine receptor. Proc Natl Acad Sci U S A 1989, 86:9762-9766.
14. Gubner N.R., McKinnon C.S., Reed C., Phillips T.J. Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation. Drug Alcohol Depend 2013, 127:108-114.
15. Jang J.Y., Jang M., Kim S.H., Um K.B., Kang Y.K., Kim H.J., Chung S., Park M.K. Regulation of dopaminergic neuron firing by heterogeneous dopamine autoreceptors in the substantia nigra pars compacta. J Neurochem 2011, 116:966-974.
16. Jomphe C., Tiberi M., Trudeau L.E. Expression of D2 receptor isoforms in cultured neurons reveals equipotent autoreceptor function. Neuropharmacology 2006, 50:595-605.
17. Kamens H.M., Burkhart-Kasch S., McKinnon C.S., Li N., Reed C., Phillips T.J. Sensitivity to psychostimulants in mice bred for high and low stimulation to methamphetamine. Genes Brain Behav 2005, 4:110-125.
18. Kelly M.A., Rubinstein M., Asa S.L., Zhang G., Saez C., Bunzow J.R., Allen R.G., Hnasko R., Ben-Jonathan N., Grandy D.K., Low M.J. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron 1997, 19:103-113.
19. Kelly M.A., Rubinstein M., Phillips T.J., Lessov C.N., Burkhart-Kasch S., Zhang G., Bunzow J.R., Fang Y., Gerhardt G.A., Grandy D.K., Low M.J. Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations. J Neurosci 1998, 18:3470-3479.
20. Kelly M.A., Low M.J., Rubinstein M., Phillips T.J. Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes Brain Behav 2008, 7:568-577.
21. Khan Z.U., Mrzljak L., Gutierrez A., De la Calle A., Goldman-Rakic P.S. Prominence of the dopamine D2 short isoform in dopaminergic pathways. Proc Natl Acad Sci U S A 1998, 95:7731-7736.
22. Lindgren N., Usiello A., Goiny M., Haycock J., Erbs E., Greengard P., Hökfelt T., Borrelli E., Fisone G. Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites. Proc Natl Acad Sci U S A 2003, 100:4305-4309.
23. Marshall J.F., Ruskin D.N., Lahoste G.J. D1/D2 dopamine receptor interactions in basal ganglia. The dopamine receptors 1997, 193-219. Humana Press, Totawa, NJ. K.A. Neve, R.L. Neve (Eds.).
24. 2 receptor deficient mice. Neuroscience 1997, 79:323-327.
25. 2 dopamine receptors produced by alternative RNA splicing. Nature 1989, 342:926-929.
26. 2 dopamine receptor isoforms. FEBS Lett 1991, 278:239-243.
27. Neve K.A., Neve R.L., Fidel S., Janowsky A., Higgins G.A. Increased abundance of alternatively spliced forms of D-2 receptor mRNA after denervation. Proc Natl Acad Sci U S A 1991, 88:2802-2806.
28. Neve R.L., Howe J.R., Hong S., Kalb R.G. Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus. Neuroscience 1997, 79:435-447.
29. Neve K.A., Seamans J.K., Trantham-Davidson H. Dopamine receptor signaling. J Recept Signal Transduct Res 2004, 24:165-205.
30. Neve R.L., Neve K.A., Nestler E.J., Carlezon W.A. Use of herpes virus amplicon vectors to study brain disorders. BioTechniques 2005, 39:381-389.
31. Pogorelov V.M., Lanthorn T.H., Savelieva K.V. Use of a platform in an automated open-field to enhance assessment of anxiety-like behaviors in mice. J Neurosci Methods 2007, 162:222-228.
32. 2 receptors. Nature 2000, 408:199-203.
33. Wang Y., Xu R., Sasaoka T., Tonegawa S., Kung M.P., Sankoorikal E.B. Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions. J Neurosci 2000, 20:8305-8314.