Decreased EGR3 expression is related to poor prognosis in patients with gastric cancer

Journal of Molecular Histology

Volumn 44, Issue 4, 2013, Pages 463-468

  Liao, Fei ^a   Ji, Meng Yao ^a   Shen, Lei ^a   Qiu, Shi ^a   Guo, Xu Feng ^a   Dong, Wei Guo ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

EGR3; Gastric cancer; Malignant progression; Prognosis

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 3; MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH ADENOCARCINOMA; STOMACH CANCER; SURVIVAL TIME; TUMOR DIFFERENTIATION; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; EARLY GROWTH RESPONSE PROTEIN 3; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; STOMACH; STOMACH NEOPLASMS; YOUNG ADULT;

EID: 84880925226     PISSN: 15672379     EISSN: 15672387     Source Type: Journal    
DOI: 10.1007/s10735-013-9493-8     Document Type: Article

References (27)

1. Alberts SR, Cervantes A, van de Velde CJ (2003) Gastric cancer: epidemiology, pathology and treatment. Ann Oncol. 14(Suppl 2): ii31-ii36 (Pubitemid 36874136)
2. Bickmore WA et al (1992) Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript. Science 257(5067):235-237
3. Catania MV et al (1999) An enhanced expression of the immediate early gene, Egr-1, is associated with neuronal apoptosis in culture. Neuroscience 91(4):1529-1538 (Pubitemid 29234278)
4. Chang AT et al (2011) Adjuvant chemoradiation for resected gastric cancer: a 10-year experience. Gastric Cancer 14(1):63-71
5. Fan D et al (2005) Bird's-eye view on gastric cancer research of the past 25 years. J Gastroenterol Hepatol 20(3):360-365 (Pubitemid 40469334)
6. Gallitano-Mendel A et al (2007) The immediate early gene early growth response gene 3 mediates adaptation to stress and novelty. Neuroscience 148(3):633-643 (Pubitemid 47418369)
7. Huang RP et al (1994) Suppression of v-sis-dependent transformation by the transcription factor, Egr-1. Oncogene 9(5):1367-1377
8. Huang RP et al (1995) Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain. Cancer Res 55(21):5054-5062
9. Huang RP et al (1997) Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation. Int J Cancer 72(1):102-109
10. Jemal A et al (2011) Global cancer statistics. CA Cancer J Clin 61(2):69-90
11. Ji MY et al (2012) The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells. J Mol Histol 43(5):517-526
12. Johnson AH et al (2005) Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis. Am J Pathol 167(2):577-584 (Pubitemid 43026111)
13. Kang W et al (2011) Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. Clin Cancer Res 17(8):2130-2139
14. Lee SL et al (1996) Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273(5279):1219-1221 (Pubitemid 26293210)
15. Liang S et al (2011) MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer. PLoS ONE 6(4):e18409
16. Liu C et al (1998) Suppression of growth and transformation and induction of apoptosis by EGR-1. Cancer Gene Ther 5(1):3-28 (Pubitemid 128639987)
17. Lu J et al (2012) Analysis on the clinical and pathological features and prognosis of familial gastric cancer in South china population: a single-center study of 724 patients. J Oncol 2012:641218
18. Miettinen S, Ylikomi T (2009) Concomitant exposure of ovarian cancer cells to docetaxel, CPT-11 or SN-38 and adenovirus-mediated p53 gene therapy. Anticancer Drugs 20(7):589-600
19. Padua D et al (2008) TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133(1):66-77 (Pubitemid 351442989)
20. Patwardhan S et al (1991) EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors. Oncogene 6(6):917-928 (Pubitemid 121000103)
21. Sela U et al (2008) A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3. J Immunol 180(3):1584-1591
22. Suehiro J et al (2010) Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3. Blood 115(12):2520-2532
23. Tang S et al (2010) Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer. Cancer Biol Ther 9(2):88-95
24. Tourtellotte WG et al (2001) The transcription factor Egr3 modulates sensory axon-myotube interactions during muscle spindle morphogenesis. Dev Biol 232(2):388-399 (Pubitemid 32337102)
25. Wang H et al (2012) A feasibility study on gene therapy of pancreatic carcinoma with Ad-PUMA. Cancer Biol Ther 13(9):712-719
26. Yan SF et al (2000) Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress. Nat Med 6(12):1355-1361 (Pubitemid 32001019)
27. Zandarashvili L et al (2012) Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1. Proc Natl Acad Sci USA 109(26):E1724-E1732