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Volumn 9, Issue 2, 2010, Pages 88-95

Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer

Author keywords

Carcinogenesis; Cell cycle; Colorectal cancer; CyclinD1; Gankyrin; Nude mouse experiment; catenin

Indexed keywords

BETA CATENIN; CYCLIN D1; GANKYRIN; MESSENGER RNA; ONCOPROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; HYBRID PROTEIN; PROTEASOME; PSMD10 PROTEIN, HUMAN; RNA; TUMOR PROTEIN;

EID: 85046915363     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.9.2.10283     Document Type: Article
Times cited : (56)

References (24)
  • 2
    • 27744507676 scopus 로고    scopus 로고
    • Increasing incidence of colorectal cancer in Asia: Implications for screening
    • Sung JJY, Lau JYW, Goh KL. Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol 2005; 6:871-6.
    • (2005) Lancet Oncol , vol.6 , pp. 871-876
    • Sung, J.J.Y.1    Lau, J.Y.W.2    Goh, K.L.3
  • 3
    • 67349145240 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells
    • Deng H, Ravikumar TS, Yang WL. Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells. Cancer Lett 2009; 281:220-31.
    • (2009) Cancer Lett , vol.281 , pp. 220-231
    • Deng, H.1    Ravikumar, T.S.2    Yang, W.L.3
  • 4
    • 63449141723 scopus 로고    scopus 로고
    • The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo
    • Zhang X, Ge Y, Tian R. The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo. Cell Mol Biol Lett 2009; 14:305-18.
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 305-318
    • Zhang, X.1    Ge, Y.2    Tian, R.3
  • 5
    • 60549099721 scopus 로고    scopus 로고
    • Loss of PHLPP expression in colon cancer: Role in proliferation and tumorigenesis
    • Liu J, Weiss HL, Rychahou P, Jackson LN, Evers BM, Gao T. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Oncogene 2009; 28:994-1004.
    • (2009) Oncogene , vol.28 , pp. 994-1004
    • Liu, J.1    Weiss, H.L.2    Rychahou, P.3    Jackson, L.N.4    Evers, B.M.5    Gao, T.6
  • 6
    • 0347093301 scopus 로고    scopus 로고
    • The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53
    • Krzywda S, Brzozowski AM, Higashitsuji H, Fujita J, Welchman R, Dawson S, et al. The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53. J Biol Chem 2004; 279:1541-5.
    • (2004) J Biol Chem , vol.279 , pp. 1541-1545
    • Krzywda, S.1    Brzozowski, A.M.2    Higashitsuji, H.3    Fujita, J.4    Welchman, R.5    Dawson, S.6
  • 7
    • 4644353678 scopus 로고    scopus 로고
    • Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure-function relationship
    • Yuan C, Li J, Mahajan A, Poi MJ, Byeon IJ, Tsai MD. Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure-function relationship. Biochemistry 2004; 43:12152-61.
    • (2004) Biochemistry , vol.43 , pp. 12152-12161
    • Yuan, C.1    Li, J.2    Mahajan, A.3    Poi, M.J.4    Byeon, I.J.5    Tsai, M.D.6
  • 8
    • 0032541323 scopus 로고    scopus 로고
    • cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome
    • Hori T, Kato S, Saeki M, DeMartino GN, Slaughter CA, Takeuchi J, et al. cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome. Gene 1998; 216:113-22.
    • (1998) Gene , vol.216 , pp. 113-122
    • Hori, T.1    Kato, S.2    Saeki, M.3    DeMartino, G.N.4    Slaughter, C.A.5    Takeuchi, J.6
  • 9
    • 1442275579 scopus 로고    scopus 로고
    • X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma
    • Manjasett YBA, Quedenau C, Sievert V, Bussow K, Niesen F, Delbruck H, et al. X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma. Proteins 2004; 55:214-7.
    • (2004) Proteins , vol.55 , pp. 214-217
    • Manjasett, Y.B.A.1    Quedenau, C.2    Sievert, V.3    Bussow, K.4    Niesen, F.5    Delbruck, H.6
  • 10
    • 10744232692 scopus 로고    scopus 로고
    • Crystallization of gankyrin, an oncoprotein that interacts with CDK4 and the S6b (rpt3) ATPase of the 19S regulator of the 26S proteasome
    • Krzywda S, Brzozowski AM, Al-Safty R, Welchman R, Mee M, Dawson S, et al. Crystallization of gankyrin, an oncoprotein that interacts with CDK4 and the S6b (rpt3) ATPase of the 19S regulator of the 26S proteasome. Acta Crystallogr D Biol Crystallogr 2003; 59:1294-5.
    • (2003) Acta Crystallogr D Biol Crystallogr , vol.59 , pp. 1294-1295
    • Krzywda, S.1    Brzozowski, A.M.2    Al-Safty, R.3    Welchman, R.4    Mee, M.5    Dawson, S.6
  • 11
    • 22244486994 scopus 로고    scopus 로고
    • The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53
    • Higashitsuji H, Itoh K, Sakurai T, Nagao T, Sumitomo Y, Masuda T, et al. The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53. Cancer Cell 2005; 8:75-87.
    • (2005) Cancer Cell , vol.8 , pp. 75-87
    • Higashitsuji, H.1    Itoh, K.2    Sakurai, T.3    Nagao, T.4    Sumitomo, Y.5    Masuda, T.6
  • 12
    • 31544457877 scopus 로고    scopus 로고
    • p53 ubiquitination: Mdm2 and beyond
    • Brooks CL, Gu W. p53 ubiquitination: Mdm2 and beyond. Mol Cell 2006; 21:307-15.
    • (2006) Mol Cell , vol.21 , pp. 307-315
    • Brooks, C.L.1    Gu, W.2
  • 13
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 15
    • 36849040707 scopus 로고    scopus 로고
    • Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance
    • Ortiz CM, Ito T, Tanaka E, Tsunoda S, Nagayama S, Sakai Y, et al. Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance. Int J Cancer 2008; 122:325-32.
    • (2008) Int J Cancer , vol.122 , pp. 325-332
    • Ortiz, C.M.1    Ito, T.2    Tanaka, E.3    Tsunoda, S.4    Nagayama, S.5    Sakai, Y.6
  • 16
    • 0036678085 scopus 로고    scopus 로고
    • Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance
    • Fu XY, Wang HY, Tan L, Liu SQ, Cao HF, Wu MC. Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance. World J Gastroenterol 2002; 8:638-43.
    • (2002) World J Gastroenterol , vol.8 , pp. 638-643
    • Fu, X.Y.1    Wang, H.Y.2    Tan, L.3    Liu, S.Q.4    Cao, H.F.5    Wu, M.C.6
  • 17
    • 60849097292 scopus 로고    scopus 로고
    • Overexpression of a New Gene p28GANK Confers Multidrug Resistance of Gastric Cancer Cells
    • Li X, Zhang Y, Xiong C, Jin H, Jin B, Fan D. Overexpression of a New Gene p28GANK Confers Multidrug Resistance of Gastric Cancer Cells. Cancer Invest 2009; 27:129-39.
    • (2009) Cancer Invest , vol.27 , pp. 129-139
    • Li, X.1    Zhang, Y.2    Xiong, C.3    Jin, H.4    Jin, B.5    Fan, D.6
  • 18
    • 39549122562 scopus 로고    scopus 로고
    • Association of Gankyrin Protein Expression with Early Clinical Stages and Insulin-Like Growth Factor-Binding Protein 5 Expression in Human Hepatocellular Carcinoma
    • Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Fujita J, et al. Association of Gankyrin Protein Expression with Early Clinical Stages and Insulin-Like Growth Factor-Binding Protein 5 Expression in Human Hepatocellular Carcinoma. Hepatology 2008; 47:493-502.
    • (2008) Hepatology , vol.47 , pp. 493-502
    • Umemura, A.1    Itoh, Y.2    Itoh, K.3    Yamaguchi, K.4    Nakajima, T.5    Fujita, J.6
  • 19
    • 24644446398 scopus 로고    scopus 로고
    • Ribo-gnome: The big world of small RNAs
    • Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science 2005; 309:1519-24.
    • (2005) Science , vol.309 , pp. 1519-1524
    • Zamore, P.D.1    Haley, B.2
  • 20
  • 23
    • 75749134401 scopus 로고    scopus 로고
    • URG11 Promotes Gastric Cancer Growth and Invasion by Activation of β-Catenin Signaling Pathway
    • Du R, Xia L, Sun S, Lian Z, Liu J, Fan D, et al. URG11 Promotes Gastric Cancer Growth and Invasion by Activation of β-Catenin Signaling Pathway. J Cell Mol Med 2009.
    • (2009) J Cell Mol Med
    • Du, R.1    Xia, L.2    Sun, S.3    Lian, Z.4    Liu, J.5    Fan, D.6
  • 24
    • 60249085609 scopus 로고    scopus 로고
    • CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma
    • He L, Wang H, Jin H, Guo C, Liu J, Fan D, et al. CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. Cancer lett 2009; 276:88-94.
    • (2009) Cancer lett , vol.276 , pp. 88-94
    • He, L.1    Wang, H.2    Jin, H.3    Guo, C.4    Liu, J.5    Fan, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.