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Volumn 69, Issue 36, 2013, Pages 7559-7567
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Synthesis of piperlogs and analysis of their effects on cells
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Author keywords
Michael acceptors; Piperlongumine; Reactive oxygen species; Toxicity
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Indexed keywords
1 (3 PHENYLPROPIOLOYL) 5,6 DIHYDROPYRIDIN 2(1H)ONE;
1 (6 (3 (2,6 DIMETHOXY 4 (3 OXO 3 (2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)PROP 1 EN 1 YL)PHENOXY)PROPOXY) 5,7 DIMETHOXY 3,4 DIHYDRONAPHTHALENE 2 CARBONYL)5,6 DIHYDROPYRIDIN 2(1H) ONE;
1 ACRYLOYL 5,6 DIHYDROPYRIDIN 2(1H) ONE;
1 METHACRYLOYL 5,6 DIHYDROPYRIDIN 2(1H) ONE;
1,1' (3,3' (((((OXYBIS(ETHANE 2,1 DIYL))BIS(OXY))BIS(ETHANE 2,1 DIYL))BIS(OXY))BIS(3,5 DIMETHOXY 4,1 PHENYLENE))BIS(ACRYLOYL))BIS(5,6 DIHYDROPYRIDIN 2(1H) ONE);
1,1' (3,3' ((((ETHANE 1,2 DIYLBIS(OXY))BIS(ETHANE 2,1 DIYL))BIS(OXY))BIS(3,5 DIMETHOXY 4,1 PHENYLENE))BIS(A CRYLOYL))BIS(5,6 DIHYDROPYRIDIN 2(1H)ONE);
1,1' (3,3' (((OXYBIS(ETHANE 2,1 DIYL))BIS(OXY))BIS(3,5 DIMETHOXY 4,1 PHENYLENE))BIS(ACRYLOYL))BIS(5,6 DIHYDROPYRIDIN 2(1H)ONE);
1,1' (3,3' ((3,6,9,12 TETRAOXATETRADECANE 1,14 DIYLBIS(OXY))BIS(3,5 DIMETHOXY 4,1 PHENYLENE)BIS(ACRYLOYL))BIS(5,6 DIHYDROPYRIDIN 2(1H) ONE);
1,1' (3,3' ((PROPANE 1,3 DIYLBIS(OXY))BIS(3,5 DIMETHOXY 4,1 PHENYLENE))BIS(ACRYLOYL))BIS(5,6 DIHYDROPYRIDIN 2(1H) ONE);
1,1' (3,3' (1,4 PHENYLENE)BIS(ACRYLOYL)) BIS(5,6 DIHYDROPYRIDIN 2(1H) ONE);
1,1' (6,6' (PROPANE 1,3 DIYLBIS(OXY))BIS(5,7 DIMETHOXY 3,4 DIHYDRONAPHTHALENE 2,2' CARBONYL))BIS(5,6 DIHYDROPYRIDIN 2(1H)ONE);
1,12 BIS(2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)DODECANE 1,12 DIONE;
1,4 BIS(2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)BUTANE 1,4 DIONE;
1,4 BIS(2 OXO 5,6 DIHYDROPYRIDIN 1(2H)-YL)BUT 2 ENE 1,4 DIONE;
2,6 DIMETHOXY 4 (3 OXO 3 (2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)PROP 1 EN 1 YL)PHENYLETHYLFUMARATE;
3 (2 CYANO 3 (DIMETHYLAMINO)ACRYLAMIDO)PROPYL 3 (3,4,5 TRIMETHOXYPHENYL)ACRYLATE;
BIS(2,6 DIMETHOXY 4 (3 OXO 3 (2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)PROP 1 EN 1 YL)PHENYL)FUMARATE;
BIS(2,6 DIMETHOXY 4 (3 OXO 3 (2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)PROP 1 EN 1 YL)PROP 1 EN 1 YL)PHENYL) SUCCINATE;
BIS(2,6 DIMETHOXY 4-(3 OXO 3 (2 OXO 5,6 DIHYDROPYRIDIN 1(2H) YL)PROP 1 EN 1 YL)PHENYL)DODECANEDIOATE;
ETHYL 4 OXO 4 (2 OXO 5,6 DIHYDROPYRIDIN 1 (2H) YL)BUT 2 ENOATE;
N (3 (3,4,5 TRIMETHOXYPHENYL)ACRYLOYL) BUT 2 ENAMIDE;
N METHACRYLOYLBUT 2 ENAMIDE;
N,N' (BUTANE 1,4 DIYL)BIS(BUT 2 ENAMIDE);
N,N' (BUTANE 1,4 DIYL)DIACRYLAMIDE;
N,N' (ETHANE 1,2 DIYL)BIS(3 (3,4,5 TRIMETHOXYPHENYL)ACRYLAMIDE);
N,N' (ETHANE 1,2 DIYL)BIS(N METHYL 3 (3,4,5 TRIMETHOXYPHENYL)ACRYLAMIDE);
N,N' (PROPANE 1,3 DIYL)BIS(3 (3,4,5TRIMETHOXYPHENYL)ACRYLAMIDE);
NATURAL PRODUCT;
PIPERLONGUMINE;
UNCLASSIFIED DRUG;
ACYLATION;
ARTICLE;
CELL VIABILITY;
CELLULAR DISTRIBUTION;
CONTROLLED STUDY;
DRUG EFFECT;
DRUG SYNTHESIS;
ELECTROPHILICITY;
FEMALE;
HUMAN;
HUMAN CELL;
KNOEVENAGEL CONDENSATION;
MOLECULAR WEIGHT;
OXIDATIVE STRESS;
PERMEABILITY;
PRIORITY JOURNAL;
RING CLOSING METATHESIS;
SOLUBILITY;
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EID: 84880924042
PISSN: 00404020
EISSN: 14645416
Source Type: Journal
DOI: 10.1016/j.tet.2013.05.080 Document Type: Article |
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Times cited : (22)
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References (23)
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