Compound K increases type I procollagen level and decreases matrix metalloproteinase-1 activity and level in ultraviolet-A-irradiated fibroblasts

Journal of the Formosan Medical Association

Volumn 110, Issue 3, 2011, Pages 153-160

  He, Dawei ^a   Sun, Jianzhong ^a   Zhu, Xiaodong ^a   Nian, Shensheng ^a   Liu, Jun ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Compound K; Fibroblasts; Ginsenoside; Matrix metalloproteinase 1; Type I collagen; UVA irradiation

Indexed keywords

COLLAGEN TYPE 1; COMPOUND K; GINSENOSIDE; INTERSTITIAL COLLAGENASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; INCUBATION TIME; RADIATION DOSE; SHAM PROCEDURE; ULTRAVIOLET A RADIATION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 79955616811     PISSN: None     EISSN: 09296646     Source Type: Journal    
DOI: 10.1016/S0929-6646(11)60025-9     Document Type: Article

References (28)

1. Bruls WA, van Weelden H, van der Leun JC. Transmission of UV-radiation through human epidermal layers as a factor influencing the minimal erythema dose. Photochem Photobiol 1984;39:63-7.
2. Pearse AD, Gaskell SA, Marks R. Epidermal changes in human skin following irradiation with either UVB or UVA. J Invest Dermatol 1987;88:83-7.
3. Kochanek KS, Wlaschek M, Brenneisen P, et al. UVinduced reactive oxygen species in photocarcinogenesis and photoaging. Biol Chem 1997;378:1247-57.
4. Ma W, Wlaschek M, Tantcheva-Poor I, et al. Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue. Clin Exp Dermatol 2001;26:592-9.
5. Nagase H, Woessner JF. Matrix metalloproteinases. J Biol Chem 1999;274:21491-4.
6. Shapiro SD. Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Curr Opin Cell Biol 1998;10:602-8.
7. Fisher GJ, Kang S, Varani J, et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 2002;138: 1462-70.
8. Shin YW, Bae EA, Kim SS, et al. Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis. Int Immunopharmacol 2005;5:1183-91.
9. Kim JH, Cho SY, Lee JH, et al. Neuroprotective effects of ginsenoside Rg3 against homocysteine-induced excitotoxicity in rat hippocampus. Brain Res 2007;1136: 190-9.
10. Yoon M, Lee H, Jeong S, et al. Peroxisome proliferatoractivated receptor alpha is involved in the regulation of lipid metabolism by ginseng. Br J Pharmacol 2003;138: 1295-302.
11. Wakabayashi C, Hasegawa H, Murata J, et al. In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol Res 1998;9:411-7.
12. Bae EA, Han MJ, Choo MK, et al. Metabolism of 20(S)-and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities. Biol Pharm Bull 2002;25:58-63.
13. Bae EA, Choo MK, Park EK, et al. Metabolism of ginsenoside R(c) by human intestinal bacteria and its related antiallergic activity. Biol Pharm Bull 2002;25:743-7.
14. Hasegawa H, Sung JH, Hur JD. Ginseng intestinal bacterial metabolite IH901 as a new antimetastatic agent. Arch Pharm Res 1997;20:539-44.
15. Hastak K, Gupta S, Ahmad N, et al. Role of p53 and NFkappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene 2003;22:4851-9.
16. Eickelberg O, Kohler E, Reichenberger F, et al. Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-beta1 and TGF-beta3. Am J Physiol 1999; 276:814-24.
17. Park CH, Lee MJ, Ahn J, et al. Heat shock-induced matrix metalloproteinase (MMP)-1 and MMP-3 are mediated through ERK and JNK activation and via an autocrine interleukin-6 loop. J Invest Dermatol 2004;123:1012-9.
18. Wan Y, Belt A, Wang Z, et al. Trans-modulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes. Int J Mol Med 2001;7:329-34.
19. Scharffetter K, Wlaschek M, Hogg A. UVA irradiation induces collagenase in human dermal fibroblasts in vitro and in vivo. Arch Dermatol Res 1991;283:506-11.
20. Koivukangas V, Kalliloinen M, Autio-Harmainen H, et al. UV-irradiation induces the expression of gelatinases in human skin in vivo. Acta Derm Venerol 1994;74:279-82.
21. Petersen MJ, Hansen C, Craig S. Ultraviolet A irradiation stimulates collagenase production in cultured human fibroblasts. J Invest Dermatol 1992;99:440-4.
22. Fisher GJ, Datta SC, Talwar HS, et al. Molecular basis of suninduced premature skin ageing and retinoid antagonism. Nature 1996;379:335-9.
23. Fisher GJ, Wang ZQ, Datta SC, et al. Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 1997;337:1419-28.
24. Varani J, Warner RL, Gharaee-Kermani M. Vitamin A antagonizes decreased cell growth and elevated collagendegrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 2000;114:480-6.
25. Chung KY, Agarwal A, Uitto J, et al. An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta. J Biol Chem 1996;271:3272-8.
26. Lee JY, Shin JW, Chun KS, et al. Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin. Carcinogenesis 2005;26:359-67.
27. Jung SH, Woo MS, Kim SY, et al. Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells. Int J Cancer 2006;118:490-7.
28. Lee HU, Bae EA, Han MJ, et al. Hepatoprotective effect of ginsenoside Rb1 and compound K on tert-butyl hydroperoxide-induced liver injury. Liver Int 2005;25: 1069-73.