Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys

Diabetology and Metabolic Syndrome

Volumn 5, Issue 1, 2013, Pages

  Wang, Xiaoli ^a,b   Hansen, Barbara C ^b,c   Shi, Da ^a   Fang, Yupeng ^a,b   Du, Fenglai ^a,b   Wang, Bingdi ^a,b   Chen, Yaxiong Michael ^a   Gregoire, Francine M ^a,b   Wang, Yi Xin Jim ^a,b  

^a Crown Bioscience Inc   (China)

^b A Crown Bioscience Company at David H Murdock Research Institute (DHMRI)   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

cell failure; C peptide; Deconvolution; Diabetes; GGI; Graded glucose infusion; Hepatic insulin extraction; Insulin resistance; Insulin secretion rate; Nonhuman primate

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INFUSION; GLUCOSE INTOLERANCE; HAPLORHINI; HYPERGLYCEMIA; INSULIN CLEARANCE; INSULIN RELEASE; INSULIN RESISTANCE; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; METABOLIC CLEARANCE RATES OF INSULIN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DENATURATION;

EID: 84880913473     PISSN: None     EISSN: 17585996     Source Type: Journal    
DOI: 10.1186/1758-5996-5-40     Document Type: Article

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