Association of toll-like receptor 4 polymorphisms with diabetic foot ulcers and application of artificial neural network in DFU risk assessment in type 2 diabetes patients

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Singh, Kiran ^a   Singh, Kanhaiya ^a   Singh, Vivek Kumar ^b   Agrawal, Neeraj K ^c   Gupta, Sanjeev K ^c  

^a BANARAS HINDU UNIVERSITY   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 4; TLR4 PROTEIN, HUMAN;

ADULT; ARTICLE; ARTIFICIAL NEURAL NETWORK; CONTROLLED STUDY; DIABETIC FOOT; DIABETIC PATIENT; FEMALE; FOOT ULCER; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; COMPLICATION; GENETICS; PATHOLOGY; RISK ASSESSMENT;

DIABETES MELLITUS, TYPE 2; DIABETIC FOOT; FOOT ULCER; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HUMANS; NEURAL NETWORKS (COMPUTER); POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; TOLL-LIKE RECEPTOR 4;

EID: 84880889312     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/318686     Document Type: Article

References (39)

1. International Diabetes Federation, IDF Diabetes Atlas 2011 5th Brussels, Belgium International Diabetes Federation
2. Donohue S., Sutton-Woods P., Murray S., Lower limb amputation. Vascular Disease. Nursing and Management 2001 London, UK Whurr Publishers
3. Boulton A. J., Vileikyte L., Ragnarson-Tennvall G., Apelqvist J., The global burden of diabetic foot disease. The Lancet 2005 366 9498 1719 1724 2-s2.0-27744593541 10.1016/S0140-6736(05)67698-2 (Pubitemid 41587452)
4. Diegelmann R. F., Evans M. C., Wound healing: an overview of acute, fibrotic and delayed healing. Frontiers in Bioscience 2004 9 283 289 2-s2.0-2542478053 (Pubitemid 38925460)
5. Jeffcoate W. J., Price P., Harding K. G., Wound healing and treatments for people with diabetic foot ulcer. Diabetes/Metabolism Research and Reviews 2004 20 1 S78 S89 2-s2.0-2642543938 10.1002/dmrr.476 (Pubitemid 38714341)
6. Whitney J. D., Overview: acute and chronic wounds. Nursing Clinics of North America 2005 40 2 191 205 2-s2.0-19744374799 10.1016/j.cnur.2004.09.002 (Pubitemid 40744980)
7. Delbridge L., Ctercteko G., Fowler C., The aetiology of diabetic neuropathy ulceration of the foot. British Journal of Surgery 1985 72 1 1 6 2-s2.0-0021894295 (Pubitemid 15158847)
8. Barton G. M., A calculated response: control of inflammation by the innate immune system. Journal of Clinical Investigation 2008 118 413 420 (Pubitemid 351206528)
9. Joffre O., Nolte M. A., Sporri R., Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunological Reviews 2009 227 234 247
10. Chen L., Guo S., Ranzer M. J., DiPietro L. A., Toll-like receptor 4 has an essential role in early skin wound healing. Journal of Investigative Dermatology 2013 133 258 267
11. Ruzehaji N., Mills S. J., Melville E., Arkell R., Fitridge R., Cowin A. J., The influence of Flightless I on Toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing. BioMed Research International 2013 2013 9 389792 10.1155/2013/389792
12. Kanhaiya A. N. K., Gupta S. K., Singh K., Differential expression of toll like receptor 4 in type 2 diabetic patients with impaired wound healing. Journal of Diabetes and Metabolism 2013 4, article 260 10.4172/2155-6156.1000260
13. Arbour N. C., Lorenz E., Schutte B. C., Zabner J., Kline J. N., Jones M., Frees K., Watt J. L., Schwartz D. A., TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nature Genetics 2000 25 2 187 191 2-s2.0-0034084438 10.1038/76048 (Pubitemid 30394990)
14. Apetoh L., Ghiringhelli F., Tesniere A., Obeid M., Ortiz C., Criollo A., Mignot G., Maiuri M. C., Ullrich E., Saulnier P., Yang H., Amigorena S., Ryffel B., Barrat F. J., Saftig P., Levi F., Lidereau R., Nogues C., Mira J.-P., Chompret A., Joulin V., Clavel-Chapelon F., Bourhis J., André F., Delaloge S., Tursz T., Kroemer G., Zitvogel L., Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nature Medicine 2007 13 9 1050 1059 2-s2.0-34948820602 10.1038/nm1622 (Pubitemid 47517504)
15. Prohinar P., Rallabhandi P., Weiss J. P., Gioannini T. L., Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4. Journal of Immunology 2010 184 8 4362 4367 2-s2.0-77952774380 10.4049/jimmunol.0903142
16. Song J., Kim D. Y., Kim C. S., Kim H. J., Lee D. H., Lee H., Ko W., Lee G., The association between Toll-like receptor 4 (TLR4) polymorphisms and the risk of prostate cancer in Korean men. Cancer Genetics and Cytogenetics 2009 190 2 88 92 2-s2.0-64549116737 10.1016/j.cancergencyto.2008.12.011
17. Rumelhart D. E., Hinton G. E., Williams R. J., Rumelhart D. E., McClelland J. L., Learning internal representation by error propagation. Parallel Distributed Processing 1986 Cambridge, Mass, USA MIT Press 318 362
18. SPSS, IBM, IBM SPSS Statistics For Windows, Version 20. 0 2011 Armonk, NY, USA IBM
19. Bergmann C., Bachmann H. S., Bankfalvi A., Lotfi R., Pütter C., Wild C. A., Schuler P. J., Greve J., Hoffmann T. K., Lang S., Scherag A., Lehnerdt G. F., Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas. Journal of Translational Medicine 2011 9 1 139 147 2-s2.0-80051796334 10.1186/1479-5876-9-139
20. Arora P., Garcia-Bailo B., Dastani Z., Brenner D., Villegas A., Malik S., Spector T. D., Richards B., El-Sohemy A., Karmali M., Badawi A., Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes. BMC Medical Genetics 2011 12, article 95 2-s2.0-79960565557 10.1186/1471-2350-12-95
21. Amoli M. M., Hasani-Ranjbar S., Roohipour N., Sayahpour F. A., Amiri P., Zahedi P., Mehrab-Mohseni M., Heshmat R., Larijani B., Tavakkoly-Bazzaz J., VEGF gene polymorphism association with diabetic foot ulcer. Diabetes Research and Clinical Practice 2011 93 2 215 219 2-s2.0-80051571344 10.1016/j.diabres.2011. 04.016
22. Mogensen T. H., Pathogen recognition and inflammatory signaling in innate immune defenses. Clinical Microbiology Reviews 2009 22 2 240 273 2-s2.0-66449088641 10.1128/CMR.00046-08
23. Armant M. A., Fenton M. J., Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biology 2002 3 8, article 3011 2-s2.0-0036056315
24. Akira S., Uematsu S., Takeuchi O., Pathogen recognition and innate immunity. Cell 2006 124 4 783 801 2-s2.0-32944464648 10.1016/j.cell.2006.02.015 (Pubitemid 43261452)
25. Krieg A. M., Vollmer J., Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity. Immunological Reviews 2007 220 1 251 269 2-s2.0-35748964708 10.1111/j.1600-065X.2007.00572.x (Pubitemid 350045572)
26. Wang R.-F., Miyahara Y., Wang H. Y., Toll-like receptors and immune regulation: implications for cancer therapy. Oncogene 2008 27 2 181 189 2-s2.0-37849014248 10.1038/sj.onc.1210906
27. Biondi-Zoccai G. G. L., Abbate A., Liuzzo G., Biasucci L. M., Atherothrombosis, inflammation, and diabetes. Journal of the American College of Cardiology 2003 41 7 1071 1077 2-s2.0-0037414074 10.1016/S0735-1097(03)00088-3 (Pubitemid 36384890)
28. Gallucci S., Matzinger P., Danger signals: SOS to the immune system. Current Opinion in Immunology 2001 13 1 114 119 2-s2.0-0035139983 10.1016/S0952-7915(00)00191-6 (Pubitemid 32096970)
29. Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S., Cutting edge: toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product. Journal of Immunology 1999 162 7 3749 3752 2-s2.0-0033120081 (Pubitemid 29314747)
30. Gao B., Tsan M.-F., Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factorαrelease by murine macrophages. Journal of Biological Chemistry 2003 278 1 174 179 2-s2.0-0037414787 10.1074/jbc.M208742200 (Pubitemid 36043559)
31. Dasu M. R., Devaraj S., Park S., Jialal I., Increased Toll-Like Receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care 2010 33 4 861 868 2-s2.0-77953060025 10.2337/dc09-1799
32. Nogueira-Machado J. A., Volpe C. M. D. O., Veloso C. A., Chaves M. M., HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation. Expert Opinion on Therapeutic Targets 2011 15 8 1023 1035 2-s2.0-79960238978 10.1517/14728222.2011.575360
33. Brand S., Staudinger T., Schnitzler F., Pfennig S., Hofbauer K., Dambacher J., Seiderer J., Tillack C., Konrad A., Crispin A., Göke B., Lohse P., Ochsenkühn T., The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease. Inflammatory Bowel Diseases 2005 11 7 645 652 2-s2.0-22044432709 10.1097/01.MIB.0000168372.94907.d2 (Pubitemid 40965520)
34. Hold G. L., Rabkin C. S., Chow W.-H., Smith M. G., Gammon M. D., Risch H. A., Vaughan T. L., McColl K. E. L., Lissowska J., Zatonski W., Schoenberg J. B., Blot W. J., Mowat N. A. G., Fraumeni J. F. Jr., El-Omar E. M., A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 2007 132 3 905 912 2-s2.0-33947304959 10.1053/j.gastro.2006.12.026 (Pubitemid 46440859)
35. Achyut B. R., Ghoshal U. C., Moorchung N., Mittal B., Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions. Human Immunology 2007 68 11 901 907 2-s2.0-36849069469 10.1016/j.humimm.2007.10.006 (Pubitemid 350235728)
36. Henckaerts L., Nielsen K. R., Steffensen R., Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Critical Care Medicine 2009 37 192 201 2-s2.0-67650459943
37. Budulac S. E., Boezen H. M., Hiemstra P. S., Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease. PLoS ONE 2012 7 8 e43124
38. Miedema K. G. E., Te Poele E. M., Tissing W. J. E., Postma D. S., Koppelman G. H., De Pagter A. P., Kamps W. A., Alizadeh B. Z., Boezen H. M., De Bont E. S. J. M., Association of polymorphisms in the TLR4 gene with the risk of developing neutropenia in children with leukemia. Leukemia 2011 25 6 995 1000 2-s2.0-79958154342 10.1038/leu.2011.27
39. Rudofsky G. Jr., Reismann P., Witte S., Humpert P. M., Isermann B., Chavakis T., Tafel J., Nosikov V. V., Hamann A., Nawroth P., Bierhaus A., Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes. Diabetes Care 2004 27 1 179 183 2-s2.0-10744224562 10.2337/diacare.27.1.179 (Pubitemid 38196729)