Naturally occurring low biological reactivity lipopolysaccharides as vaccine adjuvants

Expert Review of Vaccines

Volumn 12, Issue 7, 2013, Pages 707-709

  Darveau, Richard P ^a   Chilton, Paula M ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

adjuvant; natural lipid A; vaccine

Indexed keywords

INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; PHOSPHORYL LIPID A; TOLL LIKE RECEPTOR 4; WART VIRUS VACCINE;

ADAPTIVE IMMUNITY; ALZHEIMER DISEASE; ATHEROSCLEROSIS; B LYMPHOCYTE; CHIKUNGUNYA ALPHAVIRUS; DELAYED HYPERSENSITIVITY; DISEASE ASSOCIATION; DRUG SAFETY; EBOLA VIRUS; EDITORIAL; ENDOTHELIUM CELL; ESCHERICHIA COLI; GENE ACTIVATION; HEART DISEASE; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IN VIVO STUDY; INFLAMMATION; MICROARRAY ANALYSIS; MOLECULE; NONHUMAN; PAPILLOMAVIRUS INFECTION; PRIORITY JOURNAL; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; WILD TYPE;

ADJUVANTS, IMMUNOLOGIC; HUMANS; LIPOPOLYSACCHARIDES; SALMONELLA; TOLL-LIKE RECEPTOR 4; VACCINES;

EID: 84880863338     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.2013.811181     Document Type: Editorial

References (19)

1. Garçon N, Morel S, Didierlaurent A, Descamps D, Wettendorff M, Van Mechelen M. Development of an AS04-Adjuvanted HPV vaccine with the adjuvant system approach. BioDrugs 25(4), 217-226 (2011
2. Takada H, Kotani S. Structure-function relations of lipid A. In: Bacterial Endotoxic Lipopolysaccharides. Morrison DC, Ryan JL (Eds.). CRC Press, Inc., FL, USA 107-130 (1992
3. Needham BD, Carroll SM, Giles DK, Georgiou G, Whiteley M, Trent MS. Modulating the innate immune response by combinatorial engineering of endotoxin. Proc. Natl Acad. Sci. USA 110(4), 1464-1469 (2013
4. Hashimoto M, Asai Y, Tamai R, Jinno T, Umatani K, Ogawa T. Chemical structure and immunobiological activity of lipid A from Prevotella intermedia ATCC 25611 lipopolysaccharide. FEBS Lett. 543(1-3), 98-102 (2003
5. Coats SR, Berezow AB, To TT et al. The lipid A phosphate position determines differential host Toll-like receptor 4 responses to phylogenetically related symbiotic and pathogenic bacteria. Infect. Immun. 79(1), 203-210 (2011
6. Darveau RP, Cunningham MD, Bailey T et al. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. Infect. Immun. 63(4), 1311-1317 (1995
7. Mancuso G, Midiri A, Biondo C et al. Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infect. Immun. 73(9), 5620-5627 (2005
8. Mattsby-Baltzer I, Mielniczuk Z, Larsson L, Lindgren K, Goodwin S. Lipid A in Helicobacter pylori. Infect. Immun. 60(10), 4383-4387 (1992
9. Fujiwara T, Ogawa T, Sobue S, Hamada S. Chemical, immunobiological and antigenic characterizations of lipopolysaccharides from Bacteroides gingivalis strains. J. Gen. Microbiol. 136(2), 319-326 (1990
10. Chen C, Coats SR, Bumgarner RE, Darveau RP. Hierarchical gene expression profiles of HUVEC stimulated by different lipid A structures obtained from Porphyromonas gingivalis and Escherichia coli. Cell. Microbiol. 9(4), 1028-1038 (2007
11. Mata-Haro V, Cekic C, Martin M, Chilton PM, Casella CR, Mitchell TC The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 316(5831), 1628-1632 (2007
12. Cekic C, Casella CR, Sag D et al. MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4. J. Immunol. 186(7), 3858-3865 (2011
13. Embry CA, Franchi L, Nund;ez G, Mitchell TC. Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A. Sci. Signal. 4(171), ra28 (2011
14. Gordon HA, Pesti L. The gnotobiotic animal as a tool in the study of host microbial relationships. Bacteriol. Rev. 35(4), 390-429 (1971
15. Macpherson AJ, Harris NL. Interactions between commensal intestinal bacteria and the immune system. Nat. Rev. Immunol. 4(6), 478-485 (2004
16. Macpherson AJ, Hunziker L, McCoy K, Lamarre A. IgA responses in the intestinal mucosa against pathogenic and nonpathogenic microorganisms. Microbes Infect. 3(12), 1021-1035 (2001
17. Munford RS. Sensing gram-negative bacterial lipopolysaccharides: A human disease determinant? Infect. Immun. 76(2), 454-465 (2008
18. Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc. Natl Acad. Sci. USA 105(52), 20858-20863 (2008
19. Raetz M, Hwang SH, Wilhelm CL et al. Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells. Nat. Immunol. 14(2), 136-142 (2013