Chronic airway-induced allergy in mice modifies gene expression in the brain toward insulin resistance and inflammatory responses

Journal of Neuroinflammation

Volumn 10, Issue , 2013, Pages

  Sarlus, Heela ^a   Wang, Xiuzhe ^a   Cedazo Minguez, Angel ^a   Schultzberg, Marianne ^a   Oprica, Mircea ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Allergy; Insulin signaling; Insulin degrading enzyme; Neurodegeneration; Neuroinflammation

Indexed keywords

ALLERGEN; INSULIN RECEPTOR; INSULINASE; JANUS KINASE; LIPOPOLYSACCHARIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OVALBUMIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 23; UNCLASSIFIED DRUG;

AIRWAY; ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISCRIMINANT ANALYSIS; DOWN REGULATION; FRONTAL CORTEX; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HIPPOCAMPUS; INFLAMMATION; INSULIN RESISTANCE; LATENT STRUCTURE ANALYSIS; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; ORTHOGONAL ROTATION; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

EID: 84880859265     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-10-99     Document Type: Article

References (39)

1. Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008, 9:46-56. 10.1038/nrn2297, 2919277, 18073775.
2. Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 1988, 12:123-137. 10.1016/S0149-7634(88)80004-6, 3050629.
3. Appenzeller S, Bonilha L, Rio PA, Min Li L, Costallat LT, Cendes F. Longitudinal analysis of gray and white matter loss in patients with systemic lupus erythematosus. Neuroimage 2007, 34:694-701. 10.1016/j.neuroimage.2006.09.029, 17112740.
4. Wartolowska K, Hough MG, Jenkinson M, Andersson J, Wordsworth BP, Tracey I. Structural changes of the brain in rheumatoid arthritis. Arthritis Rheum 2012, 64:371-379. 10.1002/art.33326, 21905009.
5. Ferrari CC, Tarelli R. Parkinson's disease and systemic inflammation. Parkinsons Dis 2011, 2011:436813. 3049348, 21403862.
6. Perry VH. Stress primes microglia to the presence of systemic inflammation: implications for environmental influences on the brain. Brain Behav Immun 2007, 21:45-46. 10.1016/j.bbi.2006.08.004, 17011745.
7. Masoli M, Fabian D, Holt S, Beasley R, Global Initiative for Asthma (GINA) Program The global burden of asthma: executive summary of the GINA Dissemination Committee Report. Allergy 2004, 59:469-478. 10.1111/j.1398-9995.2004.00526.x, 15080825, Global Initiative for Asthma (GINA) Program.
8. Murphy DM, O'Byrne PM. Recent advances in the pathophysiology of asthma. Chest 2010, 137:1417-1426. 10.1378/chest.09-1895, 20525652.
9. Rosenkranz MA, Busse WW, Johnstone T, Swenson CA, Crisafi GM, Jackson MM, Bosch JA, Sheridan JF, Davidson RJ. Neural circuitry underlying the interaction between emotion and asthma symptom exacerbation. Proc Natl Acad Sci U S A 2005, 102:13319-13324. 10.1073/pnas.0504365102, 1197272, 16141324.
10. Rosenkranz MA, Busse WW, Sheridan JF, Crisafi GM, Davidson RJ. Are there neurophenotypes for asthma? Functional brain imaging of the interaction between emotion and inflammation in asthma. PLoS One 2012, 7:e40921. 10.1371/journal.pone.0040921, 3411610, 22870208.
11. Basso AS, Costa-Pinto FA, Britto LR, de Sá-Rocha LC, Palermo-Neto J. Neural pathways involved in food allergy signaling in the mouse brain: role of capsaicin-sensitive afferents. Brain Res 2004, 1009:181-188. 10.1016/j.brainres.2004.02.062, 15120595.
12. Campbell A, Oldham M, Becaria A, Bondy SC, Meacher D, Sioutas C, Misra C, Mendez LB, Kleinman M. Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain. Neurotoxicology 2005, 26:133-140. 10.1016/j.neuro.2004.08.003, 15527881.
13. Sarlus H, Höglund CO, Karshikoff B, Wang X, Lekander M, Schultzberg M, Oprica M. Allergy influences the inflammatory status of the brain and enhances τ-phosphorylation. J Cell Mol Med 2012, 16:2401-2412. 10.1111/j.1582-4934.2012.01556.x, 22356650.
14. Eriksson UK, Gatz M, Dickman PW, Fratiglioni L, Pedersen NL. Asthma, eczema, rhinitis and the risk for dementia. Dement Geriatr Cogn Disord 2008, 25:148-156. 10.1159/000112729, 18097143.
15. Cordero F, Botta M, Calogero RA. Microarray data analysis and mining approaches. Brief Funct Genomic Proteomic 2007, 6:265-281.
16. Westman E, Muehlboeck JS, Simmons A. Combining MRI and CSF measures for classification of Alzheimer's disease and prediction of mild cognitive impairment conversion. Neuroimage 2012, 62:229-238. 10.1016/j.neuroimage.2012.04.056, 22580170.
17. Martens H, Høy M, Westad F, Folkenberg DMM. Analysis of designed experiments by stabilised PLS regression and jack-knifing. Chemometr Intell Lab Syst 2001, 58:151-170.
18. Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 2005, 33:W741-W748. 10.1093/nar/gki475, 1160236, 15980575.
19. Wyss-Coray T, Rogers J. Inflammation in Alzheimer disease: a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med 2012, 2:a006346. 10.1101/cshperspect.a006346, 3253025, 22315714.
20. Clark L, Wei M, Cattoretti G, Mendelsohn C, Tycko B. The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface. BMC Genet 2002, 3:11. 117226, 12102730.
21. Kim J, La S, Kim BS, Kwon BS, Kwon B. Newly identified members of the TNF receptor superfamily (mTNFRH1 and mTNFRH2) inhibit T-cell proliferation. Exp Mol Med 2003, 35:154-159. 10.1038/emm.2003.21, 12858013.
22. Wei L, Simen A, Mane S, Kaffman A. Early life stress inhibits expression of a novel innate immune pathway in the developing hippocampus. Neuropsychopharmacology 2012, 37:567-580. 10.1038/npp.2011.239, 3242319, 21993208.
23. Miyake K. Roles for accessory molecules in microbial recognition by Toll-like receptors. J Endotoxin Res 2006, 12:195-204. 10.1179/096805106X118807, 16953972.
24. Park SG, Choi JW, Kim H, Roh GS, Bok J, Go MJ, Kwack K, Oh B, Kim Y. Genome-wide profiling of antigen-induced time course expression using murine models for acute and chronic asthma. Int Arch Allergy Immunol 2008, 146:44-56. 10.1159/000112502, 18087161.
25. Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD, Dinner AR, Tang WJ. Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. EMBO J 2010, 29:3952-3966. 10.1038/emboj.2010.256, 3020635, 20959807.
26. Hickman SE, Allison EK, El Khoury J. Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice. J Neurosci 2008, 28:8354-8360. 10.1523/JNEUROSCI.0616-08.2008, 2597474, 18701698.
27. Bernstein HG, Ansorge S, Riederer P, Reiser M, Frölich L, Bogerts B. Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques. Neurosci Lett 1999, 263:161-164. 10.1016/S0304-3940(99)00135-4, 10213160.
28. Mulder SD, Veerhuis R, Blankenstein MA, Nielsen HM. The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes. Exp Neurol 2012, 233:373-379. 10.1016/j.expneurol.2011.11.001, 22101005.
29. Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. Neurons regulate extracellular levels of amyloid β-protein via proteolysis by insulin-degrading enzyme. J Neurosci 2000, 20:1657-1665.
30. Bernstein HG, Lendeckel U, Bukowska A, Ansorge S, Ernst T, Stauch R, Trübner K, Steiner J, Dobrowolny H, Bogerts B. Regional and cellular distribution patterns of insulin-degrading enzyme in the adult human brain and pituitary. J Chem Neuroanat 2008, 35:216-224. 10.1016/j.jchemneu.2007.12.001, 18226493.
31. Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC. Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest 2008, 118:2132-2147. 2350427, 18451994.
32. Farooqui AA, Farooqui T, Panza F, Frisardi V. Metabolic syndrome as a risk factor for neurological disorders. Cell Mol Life Sci 2012, 69:741-762. 10.1007/s00018-011-0840-1, 21997383.
33. Brüning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Müller-Wieland D, Kahn CR. Role of brain insulin receptor in control of body weight and reproduction. Science 2000, 289:2122-2125. 10.1126/science.289.5487.2122, 11000114.
34. Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM. Tumor necrosis factor α inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 1994, 91:4854-4858. 10.1073/pnas.91.11.4854, 43887, 8197147.
35. Wieser V, Moschen AR, Tilg H. Inflammation, cytokines and insulin resistance: a clinical perspective. Arch Immunol Ther Exp (Warsz) 2013, 61:119-125.
36. Park CR, Seeley RJ, Craft S, Woods SC. Intracerebroventricular insulin enhances memory in a passive-avoidance task. Physiol Behav 2000, 68:509-514. 10.1016/S0031-9384(99)00220-6, 10713291.
37. Mueller NT, Koh WP, Odegaard AO, Gross MD, Yuan JM, Pereira MA. Asthma and the risk of type 2 diabetes in the Singapore Chinese Health Study. Diabetes Res Clin Pract 2013, 99:192-199. 10.1016/j.diabres.2012.11.019, 23260853.
38. Park J, Kim TB, Joo H, Lee JS, Lee SD, Oh YM. Diseases concomitant with asthma in middle-aged and elderly subjects in Korea: a population-based study. Allergy Asthma Immunol Res 2013, 5:16-25. 10.4168/aair.2013.5.1.16, 3529224, 23277874.
39. Gygi SP, Rochon Y, Franza BR, Aebersold R. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 1999, 19:1720-1730. 83965, 10022859.