-
1
-
-
0034853485
-
The importance of β-cell failure in the development and progression of type 2 diabetes
-
Kahn, S.E. (2001) The importance of β-cell failure in the development and progression of type 2 diabetes. J. Clin. Endocrinol. Metab., 86 (9), 4047-4058.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, Issue.9
, pp. 4047-4058
-
-
Kahn, S.E.1
-
2
-
-
0023192941
-
Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells
-
Westermark, P., Wernstedt, C., Wilander, E., Hayden, D.W., O'Brien, T.D., and Johnson, K.H. (1987) Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc. Natl. Acad. Sci. USA, 84 (11), 3881-3885.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, Issue.11
, pp. 3881-3885
-
-
Westermark, P.1
Wernstedt, C.2
Wilander, E.3
Hayden, D.W.4
O'Brien, T.D.5
Johnson, K.H.6
-
3
-
-
0023579739
-
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
-
Cooper, G.J.S., Willis, A.C., Clark, A., Turner, R.C., Sim, R.B., and Reid, K.B.M. (1987) Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc. Natl.Acad. Sci. USA, 84 (23), 8628-8632.
-
(1987)
Proc. Natl.Acad. Sci. USA
, vol.84
, Issue.23
, pp. 8628-8632
-
-
Cooper, G.J.S.1
Willis, A.C.2
Clark, A.3
Turner, R.C.4
Sim, R.B.5
Reid, K.B.M.6
-
4
-
-
0024979572
-
Amylin hormone
-
Cooper, G.J.S., Willis, A.C., and Leighton, B. (1989) Amylin hormone. Nature, 340 (6231), 272.
-
(1989)
Nature
, vol.340
, Issue.6231
, pp. 272
-
-
Cooper, G.J.S.1
Willis, A.C.2
Leighton, B.3
-
5
-
-
1542375103
-
Islet amyloid: a complication of islet dysfunction or an aetiological factor in type 2 diabetes?
-
Clark, A. and Nilsson, M.R. (2004) Islet amyloid: a complication of islet dysfunction or an aetiological factor in type 2 diabetes? Diabetologia, 47 (2), 157-169.
-
(2004)
Diabetologia
, vol.47
, Issue.2
, pp. 157-169
-
-
Clark, A.1
Nilsson, M.R.2
-
6
-
-
0025302287
-
Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells
-
Kahn, S.E., D'Alessio, D.A., Schwartz, M.W., Fujimoto, W.Y., Ensinck, J.W., Taborsky, G.J. Jr., and Porte, D. Jr. (1990) Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes, 39 (5), 634-638.
-
(1990)
Diabetes
, vol.39
, Issue.5
, pp. 634-638
-
-
Kahn, S.E.1
D'Alessio, D.A.2
Schwartz, M.W.3
Fujimoto, W.Y.4
Ensinck, J.W.5
Taborsky Jr., G.J.6
Porte Jr., D.7
-
7
-
-
0032972592
-
Effects of sequential proline substitutions on amyloid formation by human amylin 20-29
-
Moriarty, D.F. and Raleigh, D.P. (1999) Effects of sequential proline substitutions on amyloid formation by human amylin 20-29. Biochemistry, 38 (6), 1811-1818.
-
(1999)
Biochemistry
, vol.38
, Issue.6
, pp. 1811-1818
-
-
Moriarty, D.F.1
Raleigh, D.P.2
-
8
-
-
0024230633
-
An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing
-
Sanke, T., Bell, G.I., Sample, C., Rubenstein, A.H., and Steiner, D.F. (1988) An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing. J. Biol. Chem., 263 (33), 17243-17246.
-
(1988)
J. Biol. Chem
, vol.263
, Issue.33
, pp. 17243-17246
-
-
Sanke, T.1
Bell, G.I.2
Sample, C.3
Rubenstein, A.H.4
Steiner, D.F.5
-
9
-
-
0028023652
-
Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets
-
Marcinkiewicz, M., Ramla, D., Seidah, N.G., and Chretien, M. (1994) Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets. Endocrinology, 135 (4), 1651-1660.
-
(1994)
Endocrinology
, vol.135
, Issue.4
, pp. 1651-1660
-
-
Marcinkiewicz, M.1
Ramla, D.2
Seidah, N.G.3
Chretien, M.4
-
10
-
-
0346099381
-
Role of β-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide
-
Marzban, L., Trigo-Gonzalez, G., Zhu, X., Rhodes, C.J., Halban, P.A., Steiner, D.F., and Verchere, C.B. (2004) Role of β-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide. Diabetes, 53 (1), 141-148.
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 141-148
-
-
Marzban, L.1
Trigo-Gonzalez, G.2
Zhu, X.3
Rhodes, C.J.4
Halban, P.A.5
Steiner, D.F.6
Verchere, C.B.7
-
11
-
-
0032937607
-
Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice
-
Westermark, G.T., Westermark, P., Eizirik, D.L., Hellerstrom, C., Fox, N., Steiner, D.F., and Anderson, A. (1999) Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice. Metabolism, 48 (4), 448-454.
-
(1999)
Metabolism
, vol.48
, Issue.4
, pp. 448-454
-
-
Westermark, G.T.1
Westermark, P.2
Eizirik, D.L.3
Hellerstrom, C.4
Fox, N.5
Steiner, D.F.6
Anderson, A.7
-
12
-
-
0034573325
-
Pro islet amyloid polypeptide (proIAPP) immunoreactivity in the islets of Langerhans
-
Westermark, G.T., Steiner, D.F., Gebre-Medhin, S., Engstrom, U., and Westermark, P. (2000) Pro islet amyloid polypeptide (proIAPP) immunoreactivity in the islets of Langerhans. Ups. J. Med. Sci., 105 (2), 97-106.
-
(2000)
Ups. J. Med. Sci
, vol.105
, Issue.2
, pp. 97-106
-
-
Westermark, G.T.1
Steiner, D.F.2
Gebre-Medhin, S.3
Engstrom, U.4
Westermark, P.5
-
13
-
-
21344470854
-
Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation
-
Paulsson, J.F. and Westermark, G.T. (2005) Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes, 54 (7), 2117-2125.
-
(2005)
Diabetes
, vol.54
, Issue.7
, pp. 2117-2125
-
-
Paulsson, J.F.1
Westermark, G.T.2
-
14
-
-
33646509867
-
Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in β-cells of transgenic mice over expressing the gene for human IAPP and tansplanted human islets
-
Paulsson, J.F., Andersson, A., Westermark, P., and Westermark, G.T. (2006) Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in β-cells of transgenic mice over expressing the gene for human IAPP and tansplanted human islets. Diabetologia, 49 (6), 1237-1246.
-
(2006)
Diabetologia
, vol.49
, Issue.6
, pp. 1237-1246
-
-
Paulsson, J.F.1
Andersson, A.2
Westermark, P.3
Westermark, G.T.4
-
15
-
-
0035907265
-
Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implication for islet amyloid formation
-
Park, K. and Verchere, C.B. (2001) Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implication for islet amyloid formation. J. Biol. Chem., 276 (20), 16611-16616.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.20
, pp. 16611-16616
-
-
Park, K.1
Verchere, C.B.2
-
16
-
-
51849084313
-
Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state
-
Yonemoto, I.T., Kroon, G.J., Dyson, H.J., Balch, W.E., and Kelly, J.W. (2008) Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state. Biochemistry, 47 (37), 9900-9910.
-
(2008)
Biochemistry
, vol.47
, Issue.37
, pp. 9900-9910
-
-
Yonemoto, I.T.1
Kroon, G.J.2
Dyson, H.J.3
Balch, W.E.4
Kelly, J.W.5
-
17
-
-
0035999530
-
2A adrenoceptor and phospholipid changes in hyperlipidemic rats
-
2A adrenoceptor and phospholipid changes in hyperlipidemic rats. Lipids, 37 (5), 501-506.
-
(2002)
Lipids
, vol.37
, Issue.5
, pp. 501-506
-
-
Clement, L.1
Kim-Sohn, K.A.2
Magnan, C.3
Kassis, N.4
Adnot, P.5
Kergoat, M.6
Assimacopoulos-Jeannet, F.7
Pénicaud, L.8
Hsu, F.9
Turk, J.10
Ktorza, A.11
-
18
-
-
0025917012
-
Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion
-
Wolf, B.A., Pasquals, S.M., and Turk, J. (1991) Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion. Biochemistry, 30 (26), 6372-6379.
-
(1991)
Biochemistry
, vol.30
, Issue.26
, pp. 6372-6379
-
-
Wolf, B.A.1
Pasquals, S.M.2
Turk, J.3
-
19
-
-
0023037212
-
Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids
-
Turk, J., Wolf, B.A., Lefkowith, J.B., Stump, W.T., and McDaniel, M.L. (1986) Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids. Biochim. Biophys. Acta, 879 (3), 399-409.
-
(1986)
Biochim. Biophys. Acta
, vol.879
, Issue.3
, pp. 399-409
-
-
Turk, J.1
Wolf, B.A.2
Lefkowith, J.B.3
Stump, W.T.4
McDaniel, M.L.5
-
20
-
-
33747119677
-
Conserved and cooperative assembly of membrane-bound alphahelical states of islet amyloid polypeptide
-
Knight, J.D., Hebda, J.A., and Miranker, A.D. (2006) Conserved and cooperative assembly of membrane-bound alphahelical states of islet amyloid polypeptide. Biochemistry, 45 (31), 9496-9508.
-
(2006)
Biochemistry
, vol.45
, Issue.31
, pp. 9496-9508
-
-
Knight, J.D.1
Hebda, J.A.2
Miranker, A.D.3
-
21
-
-
0033048453
-
The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles
-
Janson, J., Ashley, R.H., Harrison, D., McIntyre, S., and Butler, P.C. (1999) The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles. Diabetes, 48 (3), 491-498.
-
(1999)
Diabetes
, vol.48
, Issue.3
, pp. 491-498
-
-
Janson, J.1
Ashley, R.H.2
Harrison, D.3
McIntyre, S.4
Butler, P.C.5
-
22
-
-
4143094106
-
Phospholipid catalysis of diabetic amyloid assembly
-
Knight, J.D. and Miranker, A.D. (2004) Phospholipid catalysis of diabetic amyloid assembly. J. Mol. Biol., 341 (5), 1175-1187.
-
(2004)
J. Mol. Biol
, vol.341
, Issue.5
, pp. 1175-1187
-
-
Knight, J.D.1
Miranker, A.D.2
-
24
-
-
31344478495
-
Islet amyloid polypeptide inserts into phospholipid monolayers as monomer
-
Engel, M.F., Yigittop, H., Elgersma, R.C., Rijkers, D.T., Liskamp, R.M., de Kruijff, B., Höppener, J.W., and Antoinette Killian, J. (2006) Islet amyloid polypeptide inserts into phospholipid monolayers as monomer. J. Mol. Biol., 356 (3), 783-789.
-
(2006)
J. Mol. Biol
, vol.356
, Issue.3
, pp. 783-789
-
-
Engel, M.F.1
Yigittop, H.2
Elgersma, R.C.3
Rijkers, D.T.4
Liskamp, R.M.5
De Kruijff, B.6
Höppener, J.W.7
Antoinette Killian, J.8
-
25
-
-
43149118349
-
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
-
Maarten, F.M., Engel, L.K., Kleijer, C.C., Meeldijk, H.J.D., Jacobs, J., Verkleij, A.J., de Kruijff, B., Killian, J.A., and Höppener, J.W.M. (2008) Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane. Proc. Natl. Acad. Sci. USA, 105 (16), 6033-6038.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.16
, pp. 6033-6038
-
-
Maarten, F.M.1
Engel, L.K.2
Kleijer, C.C.3
Meeldijk, H.J.D.4
Jacobs, J.5
Verkleij, A.J.6
De Kruijff, B.7
Killian, J.A.8
Höppener, J.W.M.9
-
26
-
-
36049013172
-
Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy
-
Lopes, D.H., Meister, A., Gohlke, A., Hauser, A., Blume, A., and Winter, R. (2007) Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy. Biophys. J., 93 (9), 3132-3141.
-
(2007)
Biophys. J
, vol.93
, Issue.9
, pp. 3132-3141
-
-
Lopes, D.H.1
Meister, A.2
Gohlke, A.3
Hauser, A.4
Blume, A.5
Winter, R.6
-
27
-
-
34447621390
-
The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin
-
Grudzielanek, S., Smirnovas, V., and Winter, R. (2007) The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin. Chem. Phys. Lipids, 149 (1-2), 28-39.
-
(2007)
Chem. Phys. Lipids
, vol.149
, Issue.1-2
, pp. 28-39
-
-
Grudzielanek, S.1
Smirnovas, V.2
Winter, R.3
-
28
-
-
34547152267
-
Membrane interaction of islet amyloid polypeptide
-
Jayasinghe, S.A. and Langen, R. (2007) Membrane interaction of islet amyloid polypeptide. Biochim. Biophys. Acta, 1768, 2002-2009.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 2002-2009
-
-
Jayasinghe, S.A.1
Langen, R.2
-
29
-
-
47749117154
-
Structure of alphahelical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding
-
Apostolidou, M., Jayasinghe, S.A., and Langen, R. (2008) Structure of alphahelical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding. J. Biol. Chem., 283 (25), 17205-17210.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.25
, pp. 17205-17210
-
-
Apostolidou, M.1
Jayasinghe, S.A.2
Langen, R.3
-
30
-
-
0037167613
-
Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes
-
Anguiano, M., Nowak, R.J., and Lansbury, P.T. Jr. (2002) Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes. Biochemistry, 41 (38), 11338-11343.
-
(2002)
Biochemistry
, vol.41
, Issue.38
, pp. 11338-11343
-
-
Anguiano, M.1
Nowak, R.J.2
Lansbury Jr., P.T.3
-
31
-
-
0030044018
-
Pore formation by the cytotoxic islet amyloid peptide amylin
-
Mirzabekov, T.A., Lin, M.-C., and Kagan, B.L. (1996) Pore formation by the cytotoxic islet amyloid peptide amylin. J. Biol. Chem., 271 (4), 1988-1992.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.4
, pp. 1988-1992
-
-
Mirzabekov, T.A.1
Lin, M.-C.2
Kagan, B.L.3
-
32
-
-
48449102580
-
The effect of membranes on the in vitro fibrillation of an amyloidogenic lightchain variable-domain SMA
-
Meng, X., Fink, A.L., and Uversky, V.N. (2008) The effect of membranes on the in vitro fibrillation of an amyloidogenic lightchain variable-domain SMA. J. Mol. Biol., 381 (4), 989-999.
-
(2008)
J. Mol. Biol
, vol.381
, Issue.4
, pp. 989-999
-
-
Meng, X.1
Fink, A.L.2
Uversky, V.N.3
-
33
-
-
0141653970
-
The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies
-
Porat, Y., Kolusheva, S., Jelinek, R., and Gazit, E. (2003) The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies. Biochemistry, 42 (37), 10971-10977.
-
(2003)
Biochemistry
, vol.42
, Issue.37
, pp. 10971-10977
-
-
Porat, Y.1
Kolusheva, S.2
Jelinek, R.3
Gazit, E.4
-
34
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
-
Kayed, R., Sokolov, Y., Edmonds, B., McIntire, T.M., Milton, S.C., Hall, J.E., and Glabe, C.G. (2004) Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. J. Biol. Chem., 279 (45), 46363-46366.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.45
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
McIntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
35
-
-
4444292588
-
Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide
-
Green, J.D., Kreplak, L., Goldsbury, C., Li Blatter, X., Stolz, M., Cooper, G.S., Seelig, A., Kistler, J., and Aebi, U. (2004) Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide. J. Mol. Biol., 342 (3), 877-887.
-
(2004)
J. Mol. Biol
, vol.342
, Issue.3
, pp. 877-887
-
-
Green, J.D.1
Kreplak, L.2
Goldsbury, C.3
Li Blatter, X.4
Stolz, M.5
Cooper, G.S.6
Seelig, A.7
Kistler, J.8
Aebi, U.9
-
36
-
-
23044449398
-
Amyloid ion channels: a common structural link for protein-misfolding disease
-
Quist, A., Doudevski, I., Lin, H., Azimova, R., Ng, D., Frangione, B., Kagan, B., Ghiso, J., and Lal, R. (2005) Amyloid ion channels: a common structural link for protein-misfolding disease. Proc. Natl. Acad. Sci. USA, 102 (30), 10427-10432.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.30
, pp. 10427-10432
-
-
Quist, A.1
Doudevski, I.2
Lin, H.3
Azimova, R.4
Ng, D.5
Frangione, B.6
Kagan, B.7
Ghiso, J.8
Lal, R.9
-
37
-
-
70149116768
-
Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy
-
Soong, R., Brender, J.R., Macdonald, P.M., and Ramamoorthy, A. (2009) Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy. J. Am. Chem. Soc., 131 (20), 7079-7085.
-
(2009)
J. Am. Chem. Soc
, vol.131
, Issue.20
, pp. 7079-7085
-
-
Soong, R.1
Brender, J.R.2
Macdonald, P.M.3
Ramamoorthy, A.4
-
38
-
-
67349227494
-
Amyloidogenic propensities and conformational properties of ProIAPPand IAPP in the presence of lipid bilayer membranes
-
Jha, S., Sellin, D., Seidel, R., and Winter, R. (2009) Amyloidogenic propensities and conformational properties of ProIAPPand IAPP in the presence of lipid bilayer membranes. J. Mol. Biol., 389 (5), 907-920.
-
(2009)
J. Mol. Biol
, vol.389
, Issue.5
, pp. 907-920
-
-
Jha, S.1
Sellin, D.2
Seidel, R.3
Winter, R.4
-
39
-
-
70349560017
-
NMR spectroscopic investigation of early events in IAPP amyloid fibril formation
-
Mishra, R., Geyer, M., and Winter, R. (2009) NMR spectroscopic investigation of early events in IAPP amyloid fibril formation. ChemBioChem, 10 (11), 1769-1772.
-
(2009)
ChemBioChem
, vol.10
, Issue.11
, pp. 1769-1772
-
-
Mishra, R.1
Geyer, M.2
Winter, R.3
-
41
-
-
67650477387
-
Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study
-
Evers, F., Jeworrek, C., Tiemeyer, S., Weise, K., Sellin, D., Paulus, M., Struth, B., Tolan, M., and Winter, R. (2009) Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study. J. Am. Chem. Soc., 131 (27), 9516-9521.
-
(2009)
J. Am. Chem. Soc
, vol.131
, Issue.27
, pp. 9516-9521
-
-
Evers, F.1
Jeworrek, C.2
Tiemeyer, S.3
Weise, K.4
Sellin, D.5
Paulus, M.6
Struth, B.7
Tolan, M.8
Winter, R.9
-
42
-
-
38049125907
-
Environmental factors differently affect human and rat IAPP: conformational preferences and membrane interactions of IAPP17-29 peptide derivatives
-
Pappalardo, G., Milardi, D., Magri, A., Attanasio, F., Impellizzeri, G., La Rosa, C., Grasso, D., and Rizzarelli, E. (2007) Environmental factors differently affect human and rat IAPP: conformational preferences and membrane interactions of IAPP17-29 peptide derivatives. Chemistry, 13 (36), 10204-10215.
-
(2007)
Chemistry
, vol.13
, Issue.36
, pp. 10204-10215
-
-
Pappalardo, G.1
Milardi, D.2
Magri, A.3
Attanasio, F.4
Impellizzeri, G.5
La Rosa, C.6
Grasso, D.7
Rizzarelli, E.8
-
43
-
-
0038375258
-
Structure and positioning comparison of two variants of penetratin in two different membrane mimicking systems by NMR
-
Lindberg, M., Biverståhl, H., Gräslund, A., and Mäler, L. (2003) Structure and positioning comparison of two variants of penetratin in two different membrane mimicking systems by NMR. Eur. J. Biochem., 270 (14), 3055-3063.
-
(2003)
Eur. J. Biochem
, vol.270
, Issue.14
, pp. 3055-3063
-
-
Lindberg, M.1
Biverståhl, H.2
Gräslund, A.3
Mäler, L.4
-
44
-
-
0038374923
-
Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study
-
Mascioni, A., Porcelli, F., Ilangovan, U., Ramamoorthy, A., and Veglia, G. (2003) Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study. Biopolymers, 69 (1), 29-41.
-
(2003)
Biopolymers
, vol.69
, Issue.1
, pp. 29-41
-
-
Mascioni, A.1
Porcelli, F.2
Ilangovan, U.3
Ramamoorthy, A.4
Veglia, G.5
-
45
-
-
0028672795
-
Methods to study membrane protein structure in solution
-
Henry, G.D. and Sykes, B.D. (1994) Methods to study membrane protein structure in solution. Methods Enzymol., 239, 515-535.
-
(1994)
Methods Enzymol
, vol.239
, pp. 515-535
-
-
Henry, G.D.1
Sykes, B.D.2
-
46
-
-
0014940381
-
The gross conformation of protein-sodium dodecyl sulfate complexes
-
Reynolds, J.A. and Tanford, C. (1970) The gross conformation of protein-sodium dodecyl sulfate complexes. J. Biol. Chem., 245 (19), 5161-5165.
-
(1970)
J. Biol. Chem
, vol.245
, Issue.19
, pp. 5161-5165
-
-
Reynolds, J.A.1
Tanford, C.2
-
47
-
-
0017109004
-
Conformational properties of the complexes formed by proteins and sodium dodecyl sulfate
-
Mattice, W.L., Riser, J.M., and Clark, D.S. (1976) Conformational properties of the complexes formed by proteins and sodium dodecyl sulfate. Biochemistry, 15 (19), 4264-4272.
-
(1976)
Biochemistry
, vol.15
, Issue.19
, pp. 4264-4272
-
-
Mattice, W.L.1
Riser, J.M.2
Clark, D.S.3
-
48
-
-
33751115774
-
Fibrillogenic and non-fibrillogenic ensembles of SDSbound human alpha-synuclein
-
Ahmad, M.F., Ramakrishna, T., Raman, B., and Rao, Ch.M. (2006) Fibrillogenic and non-fibrillogenic ensembles of SDSbound human alpha-synuclein. J. Mol. Biol., 364 (5), 1061-1072.
-
(2006)
J. Mol. Biol
, vol.364
, Issue.5
, pp. 1061-1072
-
-
Ahmad, M.F.1
Ramakrishna, T.2
Raman, B.3
Rao, C.M.4
-
49
-
-
35648986681
-
Amyloid-β(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate
-
Rangachari, V., Moore, B.D., Reed, D.K., Sonoda, L.K., Bridges, A.W., Conboy, E., Hartigan, D., and Rosenberry, T.L. (2007) Amyloid-β(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate. Biochemistry, 46 (43), 12451-12462.
-
(2007)
Biochemistry
, vol.46
, Issue.43
, pp. 12451-12462
-
-
Rangachari, V.1
Moore, B.D.2
Reed, D.K.3
Sonoda, L.K.4
Bridges, A.W.5
Conboy, E.6
Hartigan, D.7
Rosenberry, T.L.8
-
50
-
-
4644335370
-
2-microglobulinrelated amyloid fibrils at a neutral pH
-
2-microglobulinrelated amyloid fibrils at a neutral pH. Biochemistry, 43 (34), 11075-11082.
-
(2004)
Biochemistry
, vol.43
, Issue.34
, pp. 11075-11082
-
-
Yamamoto, S.1
Hasegawa, K.2
Yamaguchi, I.3
Tsutsumi, S.4
Kardos, J.5
Goto, Y.6
Gejyo, F.7
Naiki, H.8
-
51
-
-
66449087200
-
Dynamic α-helix structure of micelle-bound human amylin
-
Patil, S.M., Xu, S., Sheftic, S.R., and Alexandrescu, A.T. (2009) Dynamic α-helix structure of micelle-bound human amylin. J. Biol. Chem., 284 (18), 11982-11991.
-
(2009)
J. Biol. Chem
, vol.284
, Issue.18
, pp. 11982-11991
-
-
Patil, S.M.1
Xu, S.2
Sheftic, S.R.3
Alexandrescu, A.T.4
-
52
-
-
0028920098
-
Prolines and amyloidogenicity in fragments of the Alzheimer's peptide β/A4
-
Wood, S.J., Wetzel, R., Martin, J.D., and Hurle, M.R. (1995) Prolines and amyloidogenicity in fragments of the Alzheimer's peptide β/A4. Biochemistry, 34 (3), 724-730.
-
(1995)
Biochemistry
, vol.34
, Issue.3
, pp. 724-730
-
-
Wood, S.J.1
Wetzel, R.2
Martin, J.D.3
Hurle, M.R.4
-
53
-
-
0025366838
-
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation
-
Westermark, P., Engstrom, U., Johnson, K.H., Westermark, G.T., and Betsholtz, C. (1990) Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proc. Natl. Acad. Sci. USA, 87 (13), 5036-5040.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, Issue.13
, pp. 5036-5040
-
-
Westermark, P.1
Engstrom, U.2
Johnson, K.H.3
Westermark, G.T.4
Betsholtz, C.5
-
54
-
-
77954758860
-
SDS-induced fibrillation of α-synuclein: an alternative fibrillation pathway
-
Giehm, L., Oliveira, C.L.P., Christiansen, G., Pedersen, J.S., and Otzen, D.E. (2010) SDS-induced fibrillation of α-synuclein: an alternative fibrillation pathway. J. Mol. Biol., 401, 115-133.
-
(2010)
J. Mol. Biol
, vol.401
, pp. 115-133
-
-
Giehm, L.1
Oliveira, C.L.P.2
Christiansen, G.3
Pedersen, J.S.4
Otzen, D.E.5
-
55
-
-
67349252135
-
Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol
-
Radovan, D., Opitz, N., and Winter, R. (2009) Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol. FEBS Lett., 583 (9), 1439-1445.
-
(2009)
FEBS Lett
, vol.583
, Issue.9
, pp. 1439-1445
-
-
Radovan, D.1
Opitz, N.2
Winter, R.3
-
56
-
-
77953442000
-
Interaction of hIAPP with model raft membranes and pancreatic β-cells: cytotoxicity of hIAPP oligomers
-
Weise, K., Radovan, D., Gohlke, A., Opitz, N., and Winter, R. (2010) Interaction of hIAPP with model raft membranes and pancreatic β-cells: cytotoxicity of hIAPP oligomers. ChemBioChem, 11 (9), 1280-1290.
-
(2010)
ChemBioChem
, vol.11
, Issue.9
, pp. 1280-1290
-
-
Weise, K.1
Radovan, D.2
Gohlke, A.3
Opitz, N.4
Winter, R.5
-
57
-
-
59349111854
-
Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus
-
Cho, W.-J., Jena, B.P., and Jeremic, A.M. (2008) Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus. Methods Cell. Biol., 90, 67-286.
-
(2008)
Methods Cell. Biol
, vol.90
, pp. 67-286
-
-
Cho, W.-J.1
Jena, B.P.2
Jeremic, A.M.3
-
58
-
-
0035854701
-
Visualizing detergent resistant domains in model membranes with atomic force microscopy
-
Rinia, H.A., Snel, M.M.E., van der Eerden, J.P.J.M., and de Kruijff, B. (2001) Visualizing detergent resistant domains in model membranes with atomic force microscopy. FEBS Lett., 501 (1), 92-96.
-
(2001)
FEBS Lett
, vol.501
, Issue.1
, pp. 92-96
-
-
Rinia, H.A.1
Snel, M.M.E.2
Van Der Eerden, J.P.J.M.3
De Kruijff, B.4
-
59
-
-
0033534397
-
Watching amyloid fibrils grow by time-lapse atomic force microscopy
-
Goldsbury, C., Kistler, J., Aebi, U., Arvinte, T., and Cooper, G.J.S. (1999) Watching amyloid fibrils grow by time-lapse atomic force microscopy. J. Mol. Biol., 285 (1), 33-39.
-
(1999)
J. Mol. Biol
, vol.285
, Issue.1
, pp. 33-39
-
-
Goldsbury, C.1
Kistler, J.2
Aebi, U.3
Arvinte, T.4
Cooper, G.J.S.5
-
60
-
-
1842425710
-
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation
-
Green, J.D., Goldsbury, C., Kistler, J., Cooper, G.J.S., and Aebi, U. (2004) Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J. Biol. Chem., 279 (13), 12206-12212.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.13
, pp. 12206-12212
-
-
Green, J.D.1
Goldsbury, C.2
Kistler, J.3
Cooper, G.J.S.4
Aebi, U.5
-
61
-
-
61549102154
-
Interaction of IAPP and insulin with model interfaces studied using neutron reflectometry
-
Jeworrek, C., Hollmann, O., Steiz, R., Winter, R., and Czeslik, C. (2009) Interaction of IAPP and insulin with model interfaces studied using neutron reflectometry. Biophys. J., 96 (3), 1115-1123.
-
(2009)
Biophys. J
, vol.96
, Issue.3
, pp. 1115-1123
-
-
Jeworrek, C.1
Hollmann, O.2
Steiz, R.3
Winter, R.4
Czeslik, C.5
-
62
-
-
45749108964
-
Effect of pressure on islet amyloid polypeptide aggregation: revealing the polymorphic nature of the fibrillation process
-
Radovan, D., Smirnovas, V., and Winter, R. (2008) Effect of pressure on islet amyloid polypeptide aggregation: revealing the polymorphic nature of the fibrillation process. Biochemistry, 47 (24), 6352-6360.
-
(2008)
Biochemistry
, vol.47
, Issue.24
, pp. 6352-6360
-
-
Radovan, D.1
Smirnovas, V.2
Winter, R.3
-
63
-
-
20944450871
-
Raft lipids as common components of human extracellular amyloid fibrils
-
Gellermann, G.P., Appel, T.R., Tannert, A., Radestock, A., Hortschansky, P., Schroeckh, V., Leisner, C., Lütkepohl, T., Shtrabsurg, S., Röcken, C., Pras, M., Linke, R.P., Diekmann, S., and Fändrich, M. (2005) Raft lipids as common components of human extracellular amyloid fibrils. Proc. Natl. Acad. Sci. USA, 102 (18), 6297-6302.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.18
, pp. 6297-6302
-
-
Gellermann, G.P.1
Appel, T.R.2
Tannert, A.3
Radestock, A.4
Hortschansky, P.5
Schroeckh, V.6
Leisner, C.7
Lütkepohl, T.8
Shtrabsurg, S.9
Röcken, C.10
Pras, M.11
Linke, R.P.12
Diekmann, S.13
Fändrich, M.14
-
64
-
-
0842291578
-
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
-
Merglen, A., Theander, S., Rubi, B., Chaffard, G., Wollheim, C.B., and Maechler, P. (2004) Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology, 145 (2), 667-678.
-
(2004)
Endocrinology
, vol.145
, Issue.2
, pp. 667-678
-
-
Merglen, A.1
Theander, S.2
Rubi, B.3
Chaffard, G.4
Wollheim, C.B.5
Maechler, P.6
-
65
-
-
67349142581
-
Membrane permeabilization by islet amyloid polypeptide
-
Engel, M.F.M. (2009) Membrane permeabilization by islet amyloid polypeptide. Chem. Phys. Lipids, 160 (1), 1-10.
-
(2009)
Chem. Phys. Lipids
, vol.160
, Issue.1
, pp. 1-10
-
-
Engel, M.F.M.1
-
66
-
-
76149102617
-
Evidence for proteotoxicity in b cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway
-
Gurlo, T., Ryazantsev, S., Huang, C.J., Yeh, M.W., Reber, H.A., Hines, O.J., O'Brien, T.D., Glabe, C.G., and Butler, P.C. (2010) Evidence for proteotoxicity in b cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway. Am. J. Pathol., 176 (2), 861-869.
-
(2010)
Am. J. Pathol
, vol.176
, Issue.2
, pp. 861-869
-
-
Gurlo, T.1
Ryazantsev, S.2
Huang, C.J.3
Yeh, M.W.4
Reber, H.A.5
Hines, O.J.6
O'Brien, T.D.7
Glabe, C.G.8
Butler, P.C.9
|