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Volumn 9, Issue 7, 2013, Pages

Co-expression Profiling of Autism Genes in the Mouse Brain

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; DISEASES; GENE EXPRESSION; INTELLIGENT SYSTEMS; MAMMALS;

EID: 84880774806     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003128     Document Type: Article
Times cited : (48)

References (57)
  • 2
    • 79958255914 scopus 로고    scopus 로고
    • Epidemiology: How common is autism?
    • Lord C, (2011) Epidemiology: How common is autism? Nature 474: 166-168.
    • (2011) Nature , vol.474 , pp. 166-168
    • Lord, C.1
  • 6
    • 79959262465 scopus 로고    scopus 로고
    • Transcriptomic analysis of autistic brain reveals convergent molecular pathology
    • Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, et al. (2011) Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature 474: 380-384.
    • (2011) Nature , vol.474 , pp. 380-384
    • Voineagu, I.1    Wang, X.2    Johnston, P.3    Lowe, J.K.4    Tian, Y.5
  • 7
    • 11844251366 scopus 로고    scopus 로고
    • Localized enlargement of the frontal cortex in early autism
    • Carper RA, Courchesne E, (2005) Localized enlargement of the frontal cortex in early autism. Biological Psychiatry 57: 126-133.
    • (2005) Biological Psychiatry , vol.57 , pp. 126-133
    • Carper, R.A.1    Courchesne, E.2
  • 8
    • 20544457861 scopus 로고    scopus 로고
    • Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection
    • Courchesne E, Pierce K, (2005) Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. Current Opinion in Neurobiology 15: 225-230.
    • (2005) Current Opinion in Neurobiology , vol.15 , pp. 225-230
    • Courchesne, E.1    Pierce, K.2
  • 9
    • 80051998693 scopus 로고    scopus 로고
    • Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
    • Etherton M, Foldy C, Sharma M, Tabuchi K, Liu X, et al. (2011) Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proc Natl Acad Sci U S A 108: 13764-13769.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13764-13769
    • Etherton, M.1    Foldy, C.2    Sharma, M.3    Tabuchi, K.4    Liu, X.5
  • 10
    • 79960231902 scopus 로고    scopus 로고
    • SHANK3, the synapse, and autism
    • Herbert MR, (2011) SHANK3, the synapse, and autism. N Engl J Med 365: 173-175.
    • (2011) N Engl J Med , vol.365 , pp. 173-175
    • Herbert, M.R.1
  • 11
    • 79958035893 scopus 로고    scopus 로고
    • Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses
    • Gilman SR, Iossifov I, Levy D, Ronemus M, Wigler M, et al. (2011) Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 70: 898-907.
    • (2011) Neuron , vol.70 , pp. 898-907
    • Gilman, S.R.1    Iossifov, I.2    Levy, D.3    Ronemus, M.4    Wigler, M.5
  • 12
    • 34447527654 scopus 로고    scopus 로고
    • Neuroscience - Autism's cause may reside in abnormalities at the synapse
    • Garber K, (2007) Neuroscience- Autism's cause may reside in abnormalities at the synapse. Science 317: 190-191.
    • (2007) Science , vol.317 , pp. 190-191
    • Garber, K.1
  • 14
    • 33845889998 scopus 로고    scopus 로고
    • Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders
    • Durand CM, Betancur C, Boeckers TM, Bockmann J, Chaste P, et al. (2007) Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet 39: 25-27.
    • (2007) Nat Genet , vol.39 , pp. 25-27
    • Durand, C.M.1    Betancur, C.2    Boeckers, T.M.3    Bockmann, J.4    Chaste, P.5
  • 15
    • 33847327313 scopus 로고    scopus 로고
    • Mapping autism risk loci using genetic linkage and chromosomal rearrangements
    • Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, et al. (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet 39: 319-328.
    • (2007) Nat Genet , vol.39 , pp. 319-328
    • Szatmari, P.1    Paterson, A.D.2    Zwaigenbaum, L.3    Roberts, W.4    Brian, J.5
  • 16
    • 33751257500 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridisation identifies high frequency of cryptic chromosomal rearrangements in patients with syndromic autism spectrum disorders
    • Jacquemont ML, Sanlaville D, Redon R, Raoul O, Cormier-Daire V, et al. (2006) Array-based comparative genomic hybridisation identifies high frequency of cryptic chromosomal rearrangements in patients with syndromic autism spectrum disorders. J Med Genet 43: 843-849.
    • (2006) J Med Genet , vol.43 , pp. 843-849
    • Jacquemont, M.L.1    Sanlaville, D.2    Redon, R.3    Raoul, O.4    Cormier-Daire, V.5
  • 17
    • 54049144653 scopus 로고    scopus 로고
    • Copy-number variations associated with neuropsychiatric conditions
    • Cook EH Jr, Scherer SW, (2008) Copy-number variations associated with neuropsychiatric conditions. Nature 455: 919-923.
    • (2008) Nature , vol.455 , pp. 919-923
    • Cook Jr., E.H.1    Scherer, S.W.2
  • 18
    • 79958032110 scopus 로고    scopus 로고
    • Rare de novo and transmitted copy-number variation in autistic spectrum disorders
    • Levy D, Ronemus M, Yamrom B, Lee YH, Leotta A, et al. (2011) Rare de novo and transmitted copy-number variation in autistic spectrum disorders. Neuron 70: 886-897.
    • (2011) Neuron , vol.70 , pp. 886-897
    • Levy, D.1    Ronemus, M.2    Yamrom, B.3    Lee, Y.H.4    Leotta, A.5
  • 19
    • 77957735529 scopus 로고    scopus 로고
    • A genome-wide scan for common alleles affecting risk for autism
    • Anney R, Klei L, Pinto D, Regan R, Conroy J, et al. (2010) A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet 19: 4072-4082.
    • (2010) Hum Mol Genet , vol.19 , pp. 4072-4082
    • Anney, R.1    Klei, L.2    Pinto, D.3    Regan, R.4    Conroy, J.5
  • 20
    • 79952254931 scopus 로고    scopus 로고
    • A population genetic approach to mapping neurological disorder genes using deep resequencing
    • Myers RA, Casals F, Gauthier J, Hamdan FF, Keebler J, et al. (2011) A population genetic approach to mapping neurological disorder genes using deep resequencing. PLoS Genet 7: e1001318.
    • (2011) PLoS Genet , vol.7
    • Myers, R.A.1    Casals, F.2    Gauthier, J.3    Hamdan, F.F.4    Keebler, J.5
  • 21
    • 84860297457 scopus 로고    scopus 로고
    • De novo gene disruptions in children on the autistic spectrum
    • Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, et al. (2012) De novo gene disruptions in children on the autistic spectrum. Neuron 74: 285-299.
    • (2012) Neuron , vol.74 , pp. 285-299
    • Iossifov, I.1    Ronemus, M.2    Levy, D.3    Wang, Z.4    Hakker, I.5
  • 22
    • 84860712363 scopus 로고    scopus 로고
    • Patterns and rates of exonic de novo mutations in autism spectrum disorders
    • Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, et al. (2012) Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature 485: 242-245.
    • (2012) Nature , vol.485 , pp. 242-245
    • Neale, B.M.1    Kou, Y.2    Liu, L.3    Ma'ayan, A.4    Samocha, K.E.5
  • 23
    • 84860741138 scopus 로고    scopus 로고
    • Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
    • O'Roak BJ, Vives L, Girirajan S, Karakoc E, Krumm N, et al. (2012) Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature 485: 246-250.
    • (2012) Nature , vol.485 , pp. 246-250
    • O'Roak, B.J.1    Vives, L.2    Girirajan, S.3    Karakoc, E.4    Krumm, N.5
  • 24
    • 84860780495 scopus 로고    scopus 로고
    • De novo mutations revealed by whole-exome sequencing are strongly associated with autism
    • Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, et al. (2012) De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature 485: 237-241.
    • (2012) Nature , vol.485 , pp. 237-241
    • Sanders, S.J.1    Murtha, M.T.2    Gupta, A.R.3    Murdoch, J.D.4    Raubeson, M.J.5
  • 27
    • 84860574059 scopus 로고    scopus 로고
    • Optimizing the phenotyping of rodent ASD models: Enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features
    • Buxbaum JD, Betancur C, Bozdagi O, Dorr NP, Elder GA, et al. (2012) Optimizing the phenotyping of rodent ASD models: Enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features. Mol Autism 3: 1.
    • (2012) Mol Autism , vol.3 , pp. 1
    • Buxbaum, J.D.1    Betancur, C.2    Bozdagi, O.3    Dorr, N.P.4    Elder, G.A.5
  • 28
    • 37249006214 scopus 로고    scopus 로고
    • Advances in behavioral genetics: mouse models of autism
    • Moy SS, Nadler JJ, (2008) Advances in behavioral genetics: mouse models of autism. Mol Psychiatry 13: 4-26.
    • (2008) Mol Psychiatry , vol.13 , pp. 4-26
    • Moy, S.S.1    Nadler, J.J.2
  • 31
    • 80053218338 scopus 로고    scopus 로고
    • Multi-scale correlation structure of gene expression in the brain
    • Hawrylycz M, Ng L, Page D, Morris J, Lau C, et al. (2011) Multi-scale correlation structure of gene expression in the brain. Neural Netw 24: 933-942.
    • (2011) Neural Netw , vol.24 , pp. 933-942
    • Hawrylycz, M.1    Ng, L.2    Page, D.3    Morris, J.4    Lau, C.5
  • 32
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, et al. (2007) Genome-wide atlas of gene expression in the adult mouse brain. Nature 445: 168-176.
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1    Hawrylycz, M.J.2    Ao, N.3    Ayres, M.4    Bensinger, A.5
  • 33
    • 60749125717 scopus 로고    scopus 로고
    • An anatomic gene expression atlas of the adult mouse brain
    • Ng L, Bernard A, Lau C, Overly CC, Dong HW, et al. (2009) An anatomic gene expression atlas of the adult mouse brain. Nat Neurosci 12: 356-362.
    • (2009) Nat Neurosci , vol.12 , pp. 356-362
    • Ng, L.1    Bernard, A.2    Lau, C.3    Overly, C.C.4    Dong, H.W.5
  • 34
    • 84880830525 scopus 로고    scopus 로고
    • AutDB MindSpec
    • AutDB MindSpec.
  • 35
    • 74149083446 scopus 로고    scopus 로고
    • Clustering of spatial gene expression patterns in the mouse brain and comparison with classical neuroanatomy
    • Bohland JW, Bokil H, Pathak SD, Lee CK, Ng L, et al. (2010) Clustering of spatial gene expression patterns in the mouse brain and comparison with classical neuroanatomy. Methods 50: 105-112.
    • (2010) Methods , vol.50 , pp. 105-112
    • Bohland, J.W.1    Bokil, H.2    Pathak, S.D.3    Lee, C.K.4    Ng, L.5
  • 36
    • 84880778399 scopus 로고    scopus 로고
    • Brain Gene Expression Analysis: a MATLAB toolbox for the analysis of brain-wide gene-expression data
    • arXiv:1211.6177 [q-bio.NC]
    • Grange P, Bohland JW, Hawrylycz M, Mitra PP, (2012) arXiv:1211.6177 [q-bio.NC]. Brain Gene Expression Analysis: a MATLAB toolbox for the analysis of brain-wide gene-expression data. Cornell University Library.
    • (2012) Cornell University Library
    • Grange, P.1    Bohland, J.W.2    Hawrylycz, M.3    Mitra, P.P.4
  • 37
    • 84880765742 scopus 로고    scopus 로고
    • Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas
    • P.G.M H
    • P G, M H, Mitra P, (2013) Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas. Quantitative Biology 1: 91-100.
    • (2013) Quantitative Biology , vol.1 , pp. 91-100
    • Mitra, P.1
  • 38
    • 0003124595 scopus 로고
    • A method of matrix analysis of group structure
    • Luce RD, Perry AD, (1949) A method of matrix analysis of group structure. Psychometrika 14: 95-116.
    • (1949) Psychometrika , vol.14 , pp. 95-116
    • Luce, R.D.1    Perry, A.D.2
  • 39
    • 11244306358 scopus 로고    scopus 로고
    • Discovering statistically significant biclusters in gene expression data
    • Tanay A, Sharan R, Shamir R, (2002) Discovering statistically significant biclusters in gene expression data. Bioinformatics 18 Suppl 1: S136-144.
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL.
    • Tanay, A.1    Sharan, R.2    Shamir, R.3
  • 40
    • 84868533629 scopus 로고    scopus 로고
    • Computational neuroanatomy and gene expression: Optimal sets of marker genes for brain regions
    • Princeton
    • Grange P, Mitra PP (2012) Computational neuroanatomy and gene expression: Optimal sets of marker genes for brain regions. IEEE Conference on Information Sciences and Systems. Princeton.
    • (2012) IEEE Conference on Information Sciences and Systems
    • Grange, P.1    Mitra, P.P.2
  • 42
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5
  • 43
    • 79551520605 scopus 로고    scopus 로고
    • A quantitative comparison of cell-type-specific microarray gene expression profiling methods in the mouse brain
    • Okaty BW, Sugino K, Nelson SB, (2011) A quantitative comparison of cell-type-specific microarray gene expression profiling methods in the mouse brain. PLoS One 6: e16493.
    • (2011) PLoS One , vol.6
    • Okaty, B.W.1    Sugino, K.2    Nelson, S.B.3
  • 44
    • 83055182209 scopus 로고    scopus 로고
    • A Brain Region-Specific Predictive Gene Map for Autism Derived by Profiling a Reference Gene Set
    • Kumar A, Swanwick CC, Johnson N, Menashe I, Basu SN, et al. (2011) A Brain Region-Specific Predictive Gene Map for Autism Derived by Profiling a Reference Gene Set. PLoS One 6: e28431.
    • (2011) PLoS One , vol.6
    • Kumar, A.1    Swanwick, C.C.2    Johnson, N.3    Menashe, I.4    Basu, S.N.5
  • 46
    • 77957956298 scopus 로고    scopus 로고
    • Abnormal cell patterning at the cortical gray-white matter boundary in autism spectrum disorders
    • Avino TA, Hutsler JJ, (2010) Abnormal cell patterning at the cortical gray-white matter boundary in autism spectrum disorders. Brain Res 1360: 138-146.
    • (2010) Brain Res , vol.1360 , pp. 138-146
    • Avino, T.A.1    Hutsler, J.J.2
  • 47
    • 84860367629 scopus 로고    scopus 로고
    • Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism
    • Kumar M, Kim S, Pickup S, Chen R, Fairless AH, et al. (2012) Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism. Brain Res 1455: 56-67.
    • (2012) Brain Res , vol.1455 , pp. 56-67
    • Kumar, M.1    Kim, S.2    Pickup, S.3    Chen, R.4    Fairless, A.H.5
  • 48
    • 79952668314 scopus 로고    scopus 로고
    • Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders
    • Rubenstein JL, (2011) Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders. J Child Psychol Psychiatry 52: 339-355.
    • (2011) J Child Psychol Psychiatry , vol.52 , pp. 339-355
    • Rubenstein, J.L.1
  • 49
    • 83055181202 scopus 로고    scopus 로고
    • Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study
    • Stoodley CJ, Valera EM, Schmahmann JD, (2012) Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study. Neuroimage 59: 1560-1570.
    • (2012) Neuroimage , vol.59 , pp. 1560-1570
    • Stoodley, C.J.1    Valera, E.M.2    Schmahmann, J.D.3
  • 50
    • 84859293639 scopus 로고    scopus 로고
    • Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex
    • Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, et al. (2012) Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell 149: 899-911.
    • (2012) Cell , vol.149 , pp. 899-911
    • Kwan, K.Y.1    Lam, M.M.2    Johnson, M.B.3    Dube, U.4    Shim, S.5
  • 51
    • 84860225460 scopus 로고    scopus 로고
    • Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism
    • Wegiel J, Schanen NC, Cook EH, Sigman M, Brown WT, et al. (2012) Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism. J Neuropathol Exp Neurol 71: 382-397.
    • (2012) J Neuropathol Exp Neurol , vol.71 , pp. 382-397
    • Wegiel, J.1    Schanen, N.C.2    Cook, E.H.3    Sigman, M.4    Brown, W.T.5
  • 53
    • 84871442139 scopus 로고    scopus 로고
    • Autism risk gene MET variation and cortical thickness in typically developing children and adolescents
    • Hedrick A, Lee Y, Wallace GL, Greenstein D, Clasen L, et al. (2012) Autism risk gene MET variation and cortical thickness in typically developing children and adolescents. Autism Res 5: 434-439.
    • (2012) Autism Res , vol.5 , pp. 434-439
    • Hedrick, A.1    Lee, Y.2    Wallace, G.L.3    Greenstein, D.4    Clasen, L.5
  • 54
    • 84859241496 scopus 로고    scopus 로고
    • Networks of neuronal genes affected by common and rare variants in autism spectrum disorders
    • Ben-David E, Shifman S, (2012) Networks of neuronal genes affected by common and rare variants in autism spectrum disorders. PLoS Genet 8: e1002556.
    • (2012) PLoS Genet , vol.8
    • Ben-David, E.1    Shifman, S.2
  • 55
    • 84867158871 scopus 로고    scopus 로고
    • Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins
    • Bayes A, Collins MO, Croning MD, van de Lagemaat LN, Choudhary JS, et al. (2012) Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. PLoS One 7: e46683.
    • (2012) PLoS One , vol.7
    • Bayes, A.1    Collins, M.O.2    Croning, M.D.3    van de Lagemaat, L.N.4    Choudhary, J.S.5
  • 56
    • 55449103144 scopus 로고    scopus 로고
    • Application of a translational profiling approach for the comparative analysis of CNS cell types
    • Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, et al. (2008) Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell 135: 749-762.
    • (2008) Cell , vol.135 , pp. 749-762
    • Doyle, J.P.1    Dougherty, J.D.2    Heiman, M.3    Schmidt, E.F.4    Stevens, T.R.5
  • 57
    • 84880815747 scopus 로고    scopus 로고
    • Allen Institute for Brain Science, Allen Mouse Brain Atlas [Internet]. Available from
    • Allen Institute for Brain Science, Allen Mouse Brain Atlas [Internet]. Available from: http://mouse.brain-map.org/.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.