Optimizing the phenotyping of rodent ASD models: Enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

Molecular Autism

Volumn 3, Issue 1, 2012, Pages

  Buxbaum, Joseph D ^a   Betancur, Catalina ^b,c,d   Bozdagi, Ozlem ^a   Dorr, Nate P ^a   Elder, Gregory A ^a,e   Hof, Patrick R ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b INSERM   (France)

^c Team Compensation in Neurodegenerative and Aging   (France)

^d SORBONNE UNIVERSITÉ   (France)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

autism; autism spectrum disorders; forward genetics; genetically modified mice; mouse behavior; reverse genetics; Systems biology

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTISM; BEHAVIOR CHANGE; BRAIN; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MODEL; ELECTROPHYSIOLOGY; EXCITATION; GENE; GENE DISRUPTION; GENE MUTATION; HUMAN; INHIBITION (PSYCHOLOGY); LEARNING; MEMORY; MORPHOLOGY; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SEIZURE; SENSORY DYSFUNCTION; SOCIAL BEHAVIOR;

MAMMALIA; MUS; RODENTIA;

EID: 84860574059     PISSN: None     EISSN: 20402392     Source Type: Journal    
DOI: 10.1186/2040-2392-3-1     Document Type: Review

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