-
1
-
-
0030774840
-
Anatomic heterogeneity of vascular aging: Role of nitric oxide and endothelin
-
9336378 10.1161/01.HYP.30.4.817 1:CAS:528:DyaK2sXntFSis74%3D
-
Barton M, Cosentino F, Brandes RP, Moreau P, Shaw S, Luscher TF (1997) Anatomic heterogeneity of vascular aging: role of nitric oxide and endothelin. Hypertension 30:817-824
-
(1997)
Hypertension
, vol.30
, pp. 817-824
-
-
Barton, M.1
Cosentino, F.2
Brandes, R.P.3
Moreau, P.4
Shaw, S.5
Luscher, T.F.6
-
2
-
-
9344256749
-
Mechanisms of aging-induced impairment of endothelium-dependent relaxation: Role of tetrahydrobiopterin
-
15319209 10.1152/ajpheart.00248.2004 1:CAS:528:DC%2BD2cXhtVOmurvL
-
Blackwell KA, Sorenson JP, Richardson DM, Smith LA, Suda O, Nath K, Katusic ZS (2004) Mechanisms of aging-induced impairment of endothelium- dependent relaxation: role of tetrahydrobiopterin. Am J Physiol Heart Circ Physiol 287:H2448-H2453
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Blackwell, K.A.1
Sorenson, J.P.2
Richardson, D.M.3
Smith, L.A.4
Suda, O.5
Nath, K.6
Katusic, Z.S.7
-
3
-
-
0023204180
-
Muscle respiratory capacity and VO2 max in identically trained young and old rats
-
3624129 1:STN:280:DyaL2szgslyjtw%3D%3D
-
Cartee GD, Farrar RP (1987) Muscle respiratory capacity and VO2 max in identically trained young and old rats. J Appl Physiol 63:257-261
-
(1987)
J Appl Physiol
, vol.63
, pp. 257-261
-
-
Cartee, G.D.1
Farrar, R.P.2
-
4
-
-
0028134614
-
Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction
-
7930277 10.1016/0735-1097(94)90141-4 1:STN:280:DyaK2M%2FhsFGjsg%3D%3D
-
Celermajer DS, Sorensen KE, Bull C, Robinson J, Deanfield JE (1994a) Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J Am Coll Cardiol 24:1468-1474
-
(1994)
J Am Coll Cardiol
, vol.24
, pp. 1468-1474
-
-
Celermajer, D.S.1
Sorensen, K.E.2
Bull, C.3
Robinson, J.4
Deanfield, J.E.5
-
5
-
-
0027990857
-
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women
-
8034885 10.1016/0735-1097(94)90305-0 1:STN:280:DyaK2czgvVCnsQ%3D%3D
-
Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J, Deanfield JE (1994b) Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol 24:471-476
-
(1994)
J Am Coll Cardiol
, vol.24
, pp. 471-476
-
-
Celermajer, D.S.1
Sorensen, K.E.2
Spiegelhalter, D.J.3
Georgakopoulos, D.4
Robinson, J.5
Deanfield, J.E.6
-
6
-
-
0037076784
-
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function
-
12065318 10.1161/01.RES.0000020401.61826.EA 1:CAS:528: DC%2BD38XkvV2gsLs%3D
-
Csiszar A, Ungvari Z, Edwards JG, Kaminski P, Wolin MS, Koller A, Kaley G (2002) Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res 90:1159-1166
-
(2002)
Circ Res
, vol.90
, pp. 1159-1166
-
-
Csiszar, A.1
Ungvari, Z.2
Edwards, J.G.3
Kaminski, P.4
Wolin, M.S.5
Koller, A.6
Kaley, G.7
-
7
-
-
39449118560
-
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles
-
18063659 10.1113/jphysiol.2007.147686 1:CAS:528:DC%2BD1cXivFaqu7Y%3D
-
Delp MD, Behnke BJ, Spier SA, Wu G, Muller-Delp JM (2008) Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles. J Physiol 586:1161-1168
-
(2008)
J Physiol
, vol.586
, pp. 1161-1168
-
-
Delp, M.D.1
Behnke, B.J.2
Spier, S.A.3
Wu, G.4
Muller-Delp, J.M.5
-
8
-
-
0036660626
-
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans
-
12096067 10.1113/jphysiol.2002.019166 1:CAS:528:DC%2BD38XmtVals7s%3D
-
DeSouza CA, Clevenger CM, Greiner JJ, Smith DT, Hoetzer GL, Shapiro LF, Stauffer BL (2002) Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans. J Physiol 542:255-262
-
(2002)
J Physiol
, vol.542
, pp. 255-262
-
-
Desouza, C.A.1
Clevenger, C.M.2
Greiner, J.J.3
Smith, D.T.4
Hoetzer, G.L.5
Shapiro, L.F.6
Stauffer, B.L.7
-
9
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
10376603 10.1038/21224 1:CAS:528:DyaK1MXjvFegu7s%3D
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601-605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
10
-
-
67650073156
-
Vascular endothelial dysfunction with aging: Endothelin-1 and endothelial nitric oxide synthase
-
19465546 10.1152/ajpheart.00689.2008 1:CAS:528:DC%2BD1MXovVKitb4%3D
-
Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K, Seals DR (2009) Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol 297:H425-H432
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Donato, A.J.1
Gano, L.B.2
Eskurza, I.3
Silver, A.E.4
Gates, P.E.5
Jablonski, K.6
Seals, D.R.7
-
11
-
-
0016820759
-
Aerobic power of females, ages 10 to 68
-
1141670 10.1093/geronj/30.4.385 1:STN:280:DyaE2M7ptVeltA%3D%3D
-
Drinkwater BL, Horvath SM, Wells CL (1975) Aerobic power of females, ages 10 to 68. J Gerontol 30:385-394
-
(1975)
J Gerontol
, vol.30
, pp. 385-394
-
-
Drinkwater, B.L.1
Horvath, S.M.2
Wells, C.L.3
-
12
-
-
67650354412
-
Voluntary wheel running restores endothelial function in conduit arteries of old mice: Direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase
-
19417091 10.1113/jphysiol.2009.169771 1:CAS:528:DC%2BD1MXoslequr4%3D
-
Durrant JR, Seals DR, Connell ML, Russell MJ, Lawson BR, Folian BJ, Donato AJ, Lesniewski LA (2009) Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase. J Physiol 587:3271-3285
-
(2009)
J Physiol
, vol.587
, pp. 3271-3285
-
-
Durrant, J.R.1
Seals, D.R.2
Connell, M.L.3
Russell, M.J.4
Lawson, B.R.5
Folian, B.J.6
Donato, A.J.7
Lesniewski, L.A.8
-
13
-
-
0346367324
-
Phosphorylation and activation of the endothelial nitric oxide synthase by fluid shear stress
-
10691783 10.1046/j.1365-201x.2000.00627.x 1:CAS:528:DC%2BD3cXhvVeltr0%3D
-
Fisslthaler B, Dimmeler S, Hermann C, Busse R, Fleming I (2000) Phosphorylation and activation of the endothelial nitric oxide synthase by fluid shear stress. Acta Physiol Scand 168:81-88
-
(2000)
Acta Physiol Scand
, vol.168
, pp. 81-88
-
-
Fisslthaler, B.1
Dimmeler, S.2
Hermann, C.3
Busse, R.4
Fleming, I.5
-
14
-
-
0022640297
-
Superoxide anion is involved in the breakdown of endothelium-derived relaxing factor
-
3007998 10.1038/320454a0 1:CAS:528:DyaL28XitVWisLc%3D
-
Gryglewski RJ, Palmer RM, Moncada S (1986) Superoxide anion is involved in the breakdown of endothelium-derived relaxing factor. Nature 320:454-456
-
(1986)
Nature
, vol.320
, pp. 454-456
-
-
Gryglewski, R.J.1
Palmer, R.M.2
Moncada, S.3
-
15
-
-
0028350791
-
Normal cardiopulmonary responses during incremental exercise in 20- to 70-year-old men
-
8007799 1:STN:280:DyaK2c3ns1ygtw%3D%3D
-
Inbar O, Oren A, Scheinowitz M, Rotstein A, Dlin R, Casaburi R (1994) Normal cardiopulmonary responses during incremental exercise in 20- to 70-year-old men. Med Sci Sports Exerc 26:538-546
-
(1994)
Med Sci Sports Exerc
, vol.26
, pp. 538-546
-
-
Inbar, O.1
Oren, A.2
Scheinowitz, M.3
Rotstein, A.4
Dlin, R.5
Casaburi, R.6
-
16
-
-
0023641106
-
Age-related change in skeletal muscle blood flow in the rat
-
3680885 10.1093/geronj/42.6.660 1:STN:280:DyaL1c%2FmtVaqtA%3D%3D
-
Irion GL, Vasthare US, Tuma RF (1987) Age-related change in skeletal muscle blood flow in the rat. J Gerontol 42:660-665
-
(1987)
J Gerontol
, vol.42
, pp. 660-665
-
-
Irion, G.L.1
Vasthare, U.S.2
Tuma, R.F.3
-
17
-
-
0032841717
-
Hindlimb unweighting decreases ecNOS gene expression and endothelium-dependent dilation in rat soleus feed arteries
-
10517781 1:STN:280:DyaK1MvkslOntw%3D%3D
-
Jasperse JL, Woodman CR, Price EM, Hasser EM, Laughlin MH (1999) Hindlimb unweighting decreases ecNOS gene expression and endothelium-dependent dilation in rat soleus feed arteries. J Appl Physiol 87:1476-1482
-
(1999)
J Appl Physiol
, vol.87
, pp. 1476-1482
-
-
Jasperse, J.L.1
Woodman, C.R.2
Price, E.M.3
Hasser, E.M.4
Laughlin, M.H.5
-
18
-
-
0026316875
-
Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels
-
1750529 1:STN:280:DyaK38%2Fosl2hsQ%3D%3D
-
Kuo L, Chilian WM, Davis MJ (1991) Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels. Am J Physiol 261:H1706-H1715
-
(1991)
Am J Physiol
, vol.261
-
-
Kuo, L.1
Chilian, W.M.2
Davis, M.J.3
-
19
-
-
0002715772
-
Cardiovascular system
-
Masoro EJ (ed) Oxford Univ. Press, New York
-
Lakatta EG (1995) Cardiovascular system. In: Masoro EJ (ed) Handbook of physiology: aging. Oxford Univ. Press, New York, pp 413-474
-
(1995)
Handbook of Physiology: Aging
, pp. 413-474
-
-
Lakatta, E.G.1
-
20
-
-
57349145279
-
Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles
-
18835919 10.1152/ajpheart.00541.2008 1:CAS:528:DC%2BD1cXhsFSntb3K
-
LeBlanc AJ, Shipley RD, Kang LS, Muller-Delp JM (2008) Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles. Am J Physiol Heart Circ Physiol 295:H2280-H2288
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Leblanc, A.J.1
Shipley, R.D.2
Kang, L.S.3
Muller-Delp, J.M.4
-
22
-
-
0347993717
-
Altered regional blood flow responses to submaximal exercise in older rats
-
12959955 10.1152/japplphysiol.00729.2003
-
Musch TI, Eklund KE, Hageman KS, Poole DC (2004) Altered regional blood flow responses to submaximal exercise in older rats. J Appl Physiol 96:81-88
-
(2004)
J Appl Physiol
, vol.96
, pp. 81-88
-
-
Musch, T.I.1
Eklund, K.E.2
Hageman, K.S.3
Poole, D.C.4
-
23
-
-
0142211405
-
Impaired leg vasodilation during dynamic exercise in healthy older women
-
12882993
-
Proctor DN, Koch DW, Newcomer SC, Le KU, Leuenberger UA (2003) Impaired leg vasodilation during dynamic exercise in healthy older women. J Appl Physiol 95:1963-1970
-
(2003)
J Appl Physiol
, vol.95
, pp. 1963-1970
-
-
Proctor, D.N.1
Koch, D.W.2
Newcomer, S.C.3
Le, K.U.4
Leuenberger, U.A.5
-
24
-
-
33748288089
-
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: Evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A
-
16930126 10.1111/j.1474-9726.2006.00232.x 1:CAS:528:DC%2BD28XhtFSisb3P
-
Smith AR, Visioli F, Frei B, Hagen TM (2006a) Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A. Aging Cell 5:391-400
-
(2006)
Aging Cell
, vol.5
, pp. 391-400
-
-
Smith, A.R.1
Visioli, F.2
Frei, B.3
Hagen, T.M.4
-
25
-
-
33748917958
-
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age
-
16982030 10.1016/j.abb.2006.02.017 1:CAS:528:DC%2BD28XhtVagurfP
-
Smith AR, Visioli F, Hagen TM (2006b) Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age. Arch Biochem Biophys 454:100-105
-
(2006)
Arch Biochem Biophys
, vol.454
, pp. 100-105
-
-
Smith, A.R.1
Visioli, F.2
Hagen, T.M.3
-
26
-
-
33845400838
-
Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness
-
17106067 10.1152/japplphysiol.00138.2006 1:CAS:528:DC%2BD28Xhtlent7fM
-
Soucy KG, Ryoo S, Benjo A, Lim HK, Gupta G, Sohi JS, Elser J, Aon MA, Nyhan D, Shoukas AA, Berkowitz DE (2006) Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness. J Appl Physiol 101:1751-1759
-
(2006)
J Appl Physiol
, vol.101
, pp. 1751-1759
-
-
Soucy, K.G.1
Ryoo, S.2
Benjo, A.3
Lim, H.K.4
Gupta, G.5
Sohi, J.S.6
Elser, J.7
Aon, M.A.8
Nyhan, D.9
Shoukas, A.A.10
Berkowitz, D.E.11
-
27
-
-
0028907886
-
Aging and endothelial function in normotensive subjects and patients with essential hypertension
-
7895356 10.1161/01.CIR.91.7.1981 1:STN:280:DyaK2M3gt1yiuw%3D%3D
-
Taddei S, Virdis A, Mattei P, Ghiadoni L, Gennari A, Fasolo CB, Sudano I, Salvetti A (1995) Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 91:1981-1987
-
(1995)
Circulation
, vol.91
, pp. 1981-1987
-
-
Taddei, S.1
Virdis, A.2
Mattei, P.3
Ghiadoni, L.4
Gennari, A.5
Fasolo, C.B.6
Sudano, I.7
Salvetti, A.8
-
28
-
-
66749113553
-
Exercise training reverses age-related decrements in endothelium- dependent dilation in skeletal muscle feed arteries
-
19299569 10.1152/japplphysiol.91232.2008 1:CAS:528:DC%2BD1MXnvVWmurY%3D
-
Trott DW, Gunduz F, Laughlin MH, Woodman CR (2009) Exercise training reverses age-related decrements in endothelium-dependent dilation in skeletal muscle feed arteries. J Appl Physiol 106:1925-1934
-
(2009)
J Appl Physiol
, vol.106
, pp. 1925-1934
-
-
Trott, D.W.1
Gunduz, F.2
Laughlin, M.H.3
Woodman, C.R.4
-
29
-
-
79956117923
-
NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries
-
21233343 10.1152/japplphysiol.01037.2010 1:CAS:528:DC%2BC3MXnsF2gsrw%3D
-
Trott DW, Seawright JW, Luttrell MJ, Woodman CR (2011) NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries. J Appl Physiol 110:1171-1180
-
(2011)
J Appl Physiol
, vol.110
, pp. 1171-1180
-
-
Trott, D.W.1
Seawright, J.W.2
Luttrell, M.J.3
Woodman, C.R.4
-
30
-
-
0034684652
-
Enhanced peroxynitrite formation is associated with vascular aging
-
11120770 10.1084/jem.192.12.1731
-
van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, Luscher TF (2000) Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 192:1731-1744
-
(2000)
J Exp Med
, vol.192
, pp. 1731-1744
-
-
Van Der Loo, B.1
Labugger, R.2
Skepper, J.N.3
Bachschmid, M.4
Kilo, J.5
Powell, J.M.6
Palacios-Callender, M.7
Erusalimsky, J.D.8
Quaschning, T.9
Malinski, T.10
Gygi, D.11
Ullrich, V.12
Luscher, T.F.13
-
31
-
-
0027469897
-
Feed artery role in blood flow control to rat hindlimb skeletal muscles
-
8246199 1:STN:280:DyaK2c%2Fms1Sktw%3D%3D
-
Williams DA, Segal SS (1993) Feed artery role in blood flow control to rat hindlimb skeletal muscles. J Physiol 463:631-646
-
(1993)
J Physiol
, vol.463
, pp. 631-646
-
-
Williams, D.A.1
Segal, S.S.2
-
32
-
-
0036873390
-
Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries
-
12381754
-
Woodman CR, Price EM, Laughlin MH (2002) Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries. J Appl Physiol 93:1685-1690
-
(2002)
J Appl Physiol
, vol.93
, pp. 1685-1690
-
-
Woodman, C.R.1
Price, E.M.2
Laughlin, M.H.3
-
33
-
-
0142242298
-
Selected Contribution: Aging impairs nitric oxide and prostacyclin mediation of endothelium-dependent dilation in soleus feed arteries
-
12897037 1:CAS:528:DC%2BD3sXptlWrtbY%3D
-
Woodman CR, Price EM, Laughlin MH (2003) Selected Contribution: aging impairs nitric oxide and prostacyclin mediation of endothelium-dependent dilation in soleus feed arteries. J Appl Physiol 95:2164-2170
-
(2003)
J Appl Physiol
, vol.95
, pp. 2164-2170
-
-
Woodman, C.R.1
Price, E.M.2
Laughlin, M.H.3
-
34
-
-
14144250561
-
Shear stress induces eNOS mRNA expression and improves endothelium-dependent dilation in senescent soleus muscle feed arteries
-
15531569 10.1152/japplphysiol.00408.2004 1:CAS:528:DC%2BD2MXisVCjs7o%3D
-
Woodman CR, Price EM, Laughlin MH (2005) Shear stress induces eNOS mRNA expression and improves endothelium-dependent dilation in senescent soleus muscle feed arteries. J Appl Physiol 98:940-946
-
(2005)
J Appl Physiol
, vol.98
, pp. 940-946
-
-
Woodman, C.R.1
Price, E.M.2
Laughlin, M.H.3
-
35
-
-
35348993126
-
Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries
-
17626832 10.1152/japplphysiol.00416.2007 1:CAS:528:DC%2BD2sXht1yhsbfE
-
Woodman CR, Trott DW, Laughlin MH (2007) Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries. J Appl Physiol 103:1172-1179
-
(2007)
J Appl Physiol
, vol.103
, pp. 1172-1179
-
-
Woodman, C.R.1
Trott, D.W.2
Laughlin, M.H.3
-
36
-
-
68149166789
-
Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: Role of vascular signalling kinases
-
19505983 10.1113/jphysiol.2009.172916 1:CAS:528:DC%2BD1MXhtVWns7nI
-
Zhang QJ, McMillin SL, Tanner JM, Palionyte M, Abel ED, Symons JD (2009) Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: role of vascular signalling kinases. J Physiol 587:3911-3920
-
(2009)
J Physiol
, vol.587
, pp. 3911-3920
-
-
Zhang, Q.J.1
McMillin, S.L.2
Tanner, J.M.3
Palionyte, M.4
Abel, E.D.5
Symons, J.D.6
|