The GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Goebel, Silvia ^a   Li, Zhongmin ^a   Vogelmann, Jasmin ^a   Holthoff, Hans Peter ^a   Degen, Heidrun ^a   Hermann, Dirk M ^b   Gawaz, Meinrad ^c   Ungerer, Martin ^a   Münch, Götz ^a  

^a ADVANCECOR GMBH   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; FC RECEPTOR; GLYCOPROTEIN VI; HYBRID PROTEIN; PLACEBO; RECOMBINANT PROTEIN; REVACEPT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAROTID ARTERY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; FLUORESCENCE MICROSCOPY; MIDDLE CEREBRAL ARTERY OCCLUSION; MORPHOLOGY; MOUSE; NONHUMAN; SURVIVAL; THROMBOCYTE ADHESION; TREATMENT OUTCOME;

ANIMALS; BINDING, COMPETITIVE; BLOOD PLATELETS; CELL COMMUNICATION; CEREBRAL INFARCTION; COLLAGEN; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION; MICE; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RECOVERY OF FUNCTION; REPERFUSION INJURY; STROKE; THROMBOSIS; TREATMENT OUTCOME; VENOUS THROMBOSIS; VON WILLEBRAND FACTOR;

EID: 84880753729     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066960     Document Type: Article

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