The role of oxidative and nitrosative bursts caused by azoles and amphotericin B against the fungal pathogen Cryptococcus gattii

Journal of Antimicrobial Chemotherapy

Volumn 68, Issue 8, 2013, Pages 1801-1811

  Ferreira, Gabriella Freitas ^a   Baltazar, Ludmila de Matos ^a   Alves Santos, Julliana Ribeiro ^a   Monteiro, Andrea Souza ^b   Fraga, Lucia Alves de Oliveira ^b   Resende Stoianoff, Maria Aparecida ^a   Santos, Daniel Assis ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSIDADE VALE DO RIO DOCE   (Brazil)

Author keywords

Antifungal drugs; Cryptococcosis; Peroxynitrite; Reactive oxygen species

Indexed keywords

AMITROLE; AMPHOTERICIN B; ANTIOXIDANT; DIETHYLDITHIOCARBAMIC ACID; ERGOSTEROL; FLUCONAZOLE; HYDROGEN PEROXIDE; ITRACONAZOLE; PEROXIDASE; PEROXYNITRITE; PYRROLE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANTIFUNGAL ACTIVITY; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS GATTII; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGAL CELL; FUNGUS GROWTH; IN VITRO STUDY; LIPID PEROXIDATION; MINIMUM INHIBITORY CONCENTRATION; NITROSATIVE STRESS; NONHUMAN; RESPIRATORY BURST;

ANTIFUNGAL DRUGS; CRYPTOCOCCOSIS; PEROXYNITRITE; REACTIVE OXYGEN SPECIES;

AMPHOTERICIN B; ANTIFUNGAL AGENTS; CRYPTOCOCCUS GATTII; ITRACONAZOLE; NITROSATION; PEROXYNITROUS ACID; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST;

EID: 84880748617     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt114     Document Type: Article

References (40)

1. Chayakulkeeree M, Perfect JR. Cryptococcosis. Infect Dis Clin North A 2006; 20: 507-44.
2. Giles SS, Dagenais TR, Botts MR et al. Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infect Immun 2009; 77: 3491-500.
3. Voelz K, May RC. Cryptococcal interactions with the host immune system. Eukaryot Cell 2010; 9: 835-46.
4. Byrnes EJ, Bildfell R, Frank SA et al. Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States. J Infect Dis 2009; 199: 1081-6.
5. Kronstad JW, Attarian R, Cadieux B et al. Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box. Nat Rev Microbiol 2011; 9: 193-203.
6. Trilles L, Fernández-Torres B, Lazéra MS et al. In vitro antifungal susceptibility of Cryptococcus gattii. J Clin Microbiol 2004; 42: 4815-7.
7. Chen SCA, Slavin MA, Heath CH et al. Clinical manifestations of Cryptococcus gattii infection: determinants of neurological sequelae and death. Clin Infect Dis 2012; 55: 789-98.
8. Soares BM, Santos DA, Kohler LM et al. Cerebral infection caused by Cryptococcus gattii: a case report and antifungal susceptibility testing. Rev Iberoam Micol 2008; 25: 242-5.
9. Shapiro RS, Robbins N, Cowen LE. Regulatory circuitry governing fungal: development, drug, resistance, and disease. Microbiol Mol Biol Rev 2011; 75: 213-67.
10. Matos CS, Andrade SC, Oliveira NS et al. Microbiological characteristics of clinical isolates of Cryptococcus spp. in Bahia, Brazil: molecular types and antifungal susceptibilities. Eur J Clin Microbiol Infect Dis 2012; 31: 1647-52.
11. Lamy-Freund MT, Ferreira VF, Schreier S et al. Mechanism of inactivation of the polyene antibiotic amphotericin B. Evidence for radical formation in the process of autooxidation. J Antibiot (Tokyo) 1985; 38: 753-7.
12. Sangalli-Leite F, Scorzoni L, Mesa-Arango AC et al. Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst. Microbes Infect 2011; 13: 457-67.
13. Kobayashi D, Kondo K, Uehara N et al. Endogenous reactive oxygen species is an important mediator of miconazole antifungal effect. Antimicrob Agents Chemother 2002; 46: 3113-7.
14. Vandenbosch D, Braeckmans K, Nelis HJ et al. Fungicidal activity of miconazole against Candida spp. biofilms. J Antimicrob Chemother 2010; 65: 694-700.
15. Brown SM, Campbell LT, Lodge JK. Cryptococcus neoformans, a fungus under stress. Curr Opin Microbiol 2007; 10: 320-5.
16. Clinical and Laboratory Standards Institute. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts: Approved Standard M27-A3. CLSI, Wayne, PA, USA, 2008.
17. Santos JRA, Gouveia LF, Taylor ELS et al. Dynamic interaction between fluconazole and amphotericin B against Cryptococcus gattii. Antimicrob Agents Chemother 2012; 56: 2553-8.
18. Santos JRA, Gouveia LF, Taylor ELS et al. Dynamic interaction between fluconazole and amphotericin B against Cryptococcus gattii. Antimicrob Agents Chemother
19. Hermes-Lima M, Storey KB. Antioxidant defenses and metabolic depression in a pulmonate land snail. Am J Physiol 1995; 268: 1386-93.
20. Soares BM, Alves OA, Ferreira MVL et al. Cryptococcus gattii: in vitro susceptibility to photodynamic inactivation. Photochem Photobiol 2011; 87: 357-64.
21. Khan A, Ahmad A, Akhtar F et al. Induction of oxidative stress as a possible mechanism of the antifungal action of three phenylpropanoids. FEMS Yeast Res 2011; 11: 114-22.
22. Ueda M, Kinoshita H, Yoshida T et al. Effect of catalase-specific inhibitor 3-amino-1,2,4-triazole on yeast peroxisomal catalase in vivo. FEMS Microbiol Lett 2003; 219: 93-8.
23. Hamilton AJ, Holdom MD. Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. neoformans and Cryptococcus neoformans var. gattii. Infect Immun 1997; 65: 488-94.
24. Jensen MP, Riley DP. Peroxynitrite decomposition activity of iron porphyrin complexes. Inorg Chem 2002; 41: 4788-97.
25. Lowry OH, Rosebrough NJ, Farr AL et al. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-75.
26. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47: 469-74.
27. Santos DA, Barros MES, Hamdan JS. Establishing a method of inoculum preparation for susceptibility testing of Trichophyton rubrum and Trichophyton mentagrophytes. J Clin Microbiol 2006; 44: 98-101.
28. Odds FC. Synergy, antagonism, and what the chequerboard puts between them. J Antimicrob Chemother 2003; 52: 1.
29. Jobbins SE, Hill CJ, D'Souza-Basseal JM et al. Immunoproteomic approach to elucidating the pathogenesis of cryptococcosis caused by Cryptococcus gattii. J Proteome Res 2010; 9: 3832-41.
30. Cauwenbergh G. Cryptococcal meningitis: the place of itraconazole. Mycoses 1993; 36: 221-8.
31. Espinel-Ingroff A, Aller AI, Canton E et al. Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for fluconazole, itraconazole, posaconazole and voriconazole. Antimicrob Agents Chemother 2012; 56: 5898-906.
32. Badiee P, Alborzi A. Susceptibility of clinical Candida species isolates to antifungal agents by E-test, southern Iran: a five year study. Iran J Microbiol 2011; 3: 183-8.
33. Cowen LE, Steinbach WJ. Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance. Eukaryot Cell 2008; 7: 747-64.
34. Gruszecki WI, Gagoś M, Hereć M et al. Organization of antibiotic amphotericin B in model lipid membranes. A mini review. Cell Mol Biol Lett 2003; 8: 161-70.
35. Sokol-Anderson M, Sligh JE Jr, Elberg S et al. Role of cell defense against oxidative damage in the resistance of Candida albicans to the killing effect of amphotericin B. Antimicrob Agents Chemother 1998; 32: 702-5.
36. Brown AJP, Haynes K, Quinn J. Nitrosative and oxidative stress responses in fungal pathogenicity. Curr Opin Microbiol 2009; 12: 384-91.
37. Missall T, Pusateri M, Lodge J. Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. Molec Microbiol 2004; 51: 1447-58.
38. Szabó C, Ischiropoulos H, Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 2007; 6: 662-80.
39. Virág L, Szabó E, Gergely P et al. Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. Toxicol Lett Apr 2003; 11: 113-24.
40. Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271: C1424-37.