A meta-analysis of the C1420T polymorphism in cytosolic serine hydroxymethyltransferase (SHMT1) among Caucasian colorectal cancer populations

International Journal of Colorectal Disease

Volumn 28, Issue 7, 2013, Pages 925-932

  Pabalan, Noel ^a   Jarjanazi, Hamdi ^b   Ozcelik, Hilmi ^c  

^a ANGELES UNIVERSITY FOUNDATION   (Philippines)

^b ONTARIO MINISTRY OF THE ENVIRONMENT   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

C1420T; Colorectal cancer; Cytosolic serine hydroxymethyltransferase; Gene polymorphism

Indexed keywords

CYTOSINE; DNA; FOLIC ACID; THYMINE;

ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CASE CONTROL STUDY; CAUCASIAN; CODOMINANCE; COLORECTAL CANCER; DNA POLYMORPHISM; DOMINANT INHERITANCE; ETHNIC DIFFERENCE; EVIDENCE BASED MEDICINE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MEDLINE; PRIORITY JOURNAL; RECESSIVE INHERITANCE; RISK REDUCTION; SHMT1 GENE; SYSTEMATIC REVIEW;

EID: 84880712792     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1639-3     Document Type: Article

References (45)

1. Girgis S, Suh JR, Jolivet J, Stover PJ (1997) 5-Formyltetrahydrofolate regulates homocysteine remethylation in human neuroblastoma. J Biol Chem 272:4729-4734
2. Snell K, Natsumeda Y, Weber G (1987) The modulation of serine metabolism in hepatoma 3924a during different phases of cellular proliferation in culture. Biochem J 245:609-612
3. Snell K, Natsumeda Y, Eble JN, Glover JL, Weber G (1988) Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma. Br J Cancer 57:87-90
4. Herbig K, Chiang EP, Lee LR, Hills J, Shane B, Stover PJ (2002) Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J Biol Chem 277:38381-38389
5. Sanjoaquin MA, Allen N, Couto E, Roddam AW, Key TJ (2005) Folate intake and colorectal cancer risk: a meta-analytical approach. Int J Cancer 113:825-828
6. Guerreiro CS, Carmona B, Goncalves S, Carolino E, Fidalgo P, Brito M, Leitao CN, Cravo M (2008) Risk of colorectal cancer associated with the c677t polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients. Am J Clin Nutr 88:1413-1418
7. Su LJ, Arab L (2001) Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study. Ann Epidemiol 11:65-72
8. Luebeck EG, Moolgavkar SH, Liu AY, Boynton A, Ulrich CM (2008) Does folic acid supplementation prevent or promote colorectal cancer? Results from model-based predictions. Cancer Epidemiol Biomarkers Prev 17:1360-1367
9. Mason JB, Dickstein A, Jacques PF, Haggarty P, Selhub J, Dallal G, Rosenberg IH (2007) A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev 16:1325-1329
10. Giovannucci E (2002) Epidemiologic studies of folate and colorectal neoplasia: a review. J Nutr 132:2350S-2355S
11. Van Guelpen B, Hultdin J, Johansson I, Hallmans G, Stenling R, Riboli E, Winkvist A, Palmqvist R (2006) Low folate levels may protect against colorectal cancer. Gut 55:1461-1466
12. Skibola CF, Smith MT, Hubbard A, Shane B, Roberts AC, Law GR, Rollinson S, Roman E, Cartwright RA, Morgan GJ (2002) Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 99:3786-3791
13. Hishida A, Matsuo K, Hamajima N, Ito H, Ogura M, Kagami Y, Taji H, Morishima Y, Emi N, Tajima K (2003) Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma. Haematologica 88:159-166
14. Lomnytska M, Dubrovska A, Hellman U, Volodko N, Souchelnytskyi S (2006) Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients. Int J Cancer 118:412-421
15. Wang Y, Guo W, He Y, Chen Z, Wen D, Zhang X, Wang N, Li Y, Ge H, Zhang J (2007) Association of MTHFR c677t and SHMT(1) C1420t with susceptibility to ESCC and GCA in a high incident region of Northern China. Cancer Causes Control 18:143-152
16. Vijayakrishnan J, Houlston RS (2010) Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica 95:1405-1414
17. Zhang Z, Shi Q, Sturgis EM, Spitz MR, Wei Q (2005) Polymorphisms and haplotypes of serine hydroxymethyltransferase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Pharmacogenet Genomics 15:557-564
18. Wang L, Lu J, An J, Shi Q, Spitz MR, Wei Q (2007) Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis. Lung Cancer 57:143-151 (Amsterdam, Netherlands)
19. Chen J, Kyte C, Valcin M, Chan W, Wetmur JG, Selhub J, Hunter DJ, Ma J (2004) Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. Int J Cancer 110:617-620
20. Curtin K, Ulrich CM, Samowitz WS, Wolff RK, Duggan DJ, Makar KW, Caan BJ, Slattery ML (2011) Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet 2:1-8
21. Hazra A, Wu K, Kraft P, Fuchs CS, Giovannucci EL, Hunter DJ (2007) Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the nurses' health study. Carcinogenesis 28:1510-1519
22. Komlosi V, Hitre E, Pap E, Adleff V, Reti A, Szekely E, Biro A, Rudnai P, Schoket B, Muller J, Toth B, Otto S, Kasler M, Kralovanszky J, Budai B (2010) SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer. BMC cancer 10:525
23. Koushik A, Kraft P, Fuchs CS, Hankinson SE, Willett WC, Giovannucci EL, Hunter DJ (2006) Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer. Cancer Epidemiol Biomarkers Prev 15:2408-2417
24. Steck SE, Keku T, Butler LM, Galanko J, Massa B, Millikan RC, Sandler RS (2008) Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk. J Nutrigenetics Nutrigenomics 1:196-204
25. van den Donk M, Visker MH, Harryvan JL, Kok FJ, Kampman E (2007) Dietary intake of B-vitamins, polymorphisms in thymidylate synthase and serine hydroxymethyltransferase 1, and colorectal adenoma risk: a Dutch case-control study. Cancer Lett 250:146-153
26. Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719-748
27. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177-188
28. Lau J, Ioannidis JP, Schmid CH (1997) Quantitative synthesis in systematic reviews. Ann Intern Med 127:820-826
29. Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539-1558
30. Galbraith RF (1988) A note on graphical presentation of estimated odds ratios from several clinical trials. Stat Med 7:889-894
31. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557-560 (Clinical research ed)
32. Zafarmand MH, van der Schouw YT, Grobbee DE, de Leeuw PW, Bots ML (2008) The M235t polymorphism in the AGT gene and CHD risk: evidence of a Hardy-Weinberg equilibrium violation and publication bias in a meta-analysis. PLoS One 3:e2533
33. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634 (Clinical research ed)
34. Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088-1101
35. Moore LE, Malats N, Rothman N, Real FX, Kogevinas M, Karami S, Garcia-Closas R, Silverman D, Chanock S, Welch R, Tardon A, Serra C, Carrato A, Dosemeci M, Garcia-Closas M (2007) Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer. Int J Cancer 120:2452-2458
36. Kelemen LE, Sellers TA, Schildkraut JM, Cunningham JM, Vierkant RA, Pankratz VS, Fredericksen ZS, Gadre MK, Rider DN, Liebow M, Goode EL (2008) Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. Cancer Res 68:2498-2506
37. Weiner AS, Beresina OV, Voronina EN, Voropaeva EN, Boyarskih UA, Pospelova TI, Filipenko ML (2011) Polymorphisms in folate-metabolizing genes and risk of non-Hodgkin's lymphoma. Leuk Res 35:508-515
38. Liu AY, Scherer D, Poole E, Potter JD, Curtin K, Makar K, Slattery ML, Caan BJ, Ulrich CM (2012) Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk. Mol Nutr Food Res doi: 10.1002/mnfr. 201200180
39. Collin SM, Metcalfe C, Zuccolo L, Lewis SJ, Chen L, Cox A, Davis M, Lane JA, Donovan J, Smith GD, Neal DE, Hamdy FC, Gudmundsson J, Sulem P, Rafnar T, Benediktsdottir KR, Eeles RA, Guy M, Kote-Jarai Z, Morrison J, Al Olama AA, Stefansson K, Easton DF, Martin RM (2009) Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev 18:2528-2539
40. Weiner AS, Beresina OV, Voronina EN, Voropaeva EN, Boyarskih UA, Pospelova TI, Filipenko ML (2011) Polymorphisms in folate-metabolizing genes and risk of non-Hodgkin's lymphoma. Leukemia Res 35:508-515
41. van den Donk M, Buijsse B, van den Berg SW, Ocke MC, Harryvan JL, Nagengast FM, Kok FJ, Kampman E (2005) Dietary intake of folate and riboflavin, MTHFR C677t genotype, and colorectal adenoma risk: a Dutch case-control study. Cancer Epidemiol Biomarkers Prev 14:1562-1566
42. Le Leu RK, Young GP, McIntosh GH (2000) Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis 21:2261-2265
43. Wagner C (1995) Biochemical role of folate in cellular metabolism. In: Bailey L (ed) Folate in health and disease. Marcel Dekker, New York, pp 23-42
44. Kelemen LE (2006) The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander? Int J Cancer 119:243-250
45. Cheng CW, Yu JC, Huang CS, Shieh JC, Fu YP, Wang HW, Wu PE, Shen CY (2008) Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan. Breast Cancer Res Treat 111:145-155