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Volumn 10, Issue , 2010, Pages

SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYSTEINE; GLYCINE HYDROXYMETHYLTRANSFERASE; HOMOCYSTEINE; SERINE HYDROXYMETHYLTRANSFERASE 1; THREONINE; TUMOR MARKER; UNCLASSIFIED DRUG; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); SHMT1 PROTEIN, HUMAN;

EID: 77957286796     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-525     Document Type: Article
Times cited : (38)

References (56)
  • 1
    • 0036324027 scopus 로고    scopus 로고
    • Epidemiologic studies of folate and colorectal neoplasia: a review
    • Giovannucci E. Epidemiologic studies of folate and colorectal neoplasia: a review. J Nutr 2002, 132:2350S-2355S.
    • (2002) J Nutr , vol.132
    • Giovannucci, E.1
  • 3
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review
    • 10.1093/aje/kwh066, 14977639
    • Sharp L, Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 2004, 159:423-443. 10.1093/aje/kwh066, 14977639.
    • (2004) Am J Epidemiol , vol.159 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 4
    • 11144236628 scopus 로고    scopus 로고
    • Colorectal cancer and the methylenetetrahydrofolate reductase 677C- > T and methionine synthase 2756A- > G polymorphisms: a study of 2,168 case-control pairs from the JANUS cohort
    • Ulvik A, Vollset SE, Hansen S, Gislefoss R, Jellum E, Ueland PM. Colorectal cancer and the methylenetetrahydrofolate reductase 677C- > T and methionine synthase 2756A- > G polymorphisms: a study of 2,168 case-control pairs from the JANUS cohort. Cancer Epidemiol Biomarkers Prev 2004, 13:2175-2180.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 2175-2180
    • Ulvik, A.1    Vollset, S.E.2    Hansen, S.3    Gislefoss, R.4    Jellum, E.5    Ueland, P.M.6
  • 5
    • 12344335470 scopus 로고    scopus 로고
    • Relationship between metabolic enzyme polymorphisms and colorectal cancer
    • Chen K, Jiang QT, He HQ. Relationship between metabolic enzyme polymorphisms and colorectal cancer. World J Gastroenterol 2005, 11:331-335.
    • (2005) World J Gastroenterol , vol.11 , pp. 331-335
    • Chen, K.1    Jiang, Q.T.2    He, H.Q.3
  • 6
    • 33846811416 scopus 로고    scopus 로고
    • MTHFR C677T and colorectal cancer risk: a meta-analysis of 25 populations
    • Hubner RA, Houlston RS. MTHFR C677T and colorectal cancer risk: a meta-analysis of 25 populations. Int J Cancer 2006, 120:1027-1035.
    • (2006) Int J Cancer , vol.120 , pp. 1027-1035
    • Hubner, R.A.1    Houlston, R.S.2
  • 7
    • 0037093272 scopus 로고    scopus 로고
    • Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia
    • 10.1182/blood.V99.10.3786, 11986237
    • Skibola CF, Smith MT, Hubbard A, Shane B, Roberts AC, Law GR, Rollinson S, Roman E, Cartwright RA, Morgan GJ. Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 2002, 99:3786-3791. 10.1182/blood.V99.10.3786, 11986237.
    • (2002) Blood , vol.99 , pp. 3786-3791
    • Skibola, C.F.1    Smith, M.T.2    Hubbard, A.3    Shane, B.4    Roberts, A.C.5    Law, G.R.6    Rollinson, S.7    Roman, E.8    Cartwright, R.A.9    Morgan, G.J.10
  • 8
    • 0037946769 scopus 로고    scopus 로고
    • Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma
    • Hishida A, Matsuo K, Hamajima N, Ito H, Ogura M, Kagami Y, Taji H, Morishima Y, Emi N, Tajima K. Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma. Haematologica 2003, 88:159-166.
    • (2003) Haematologica , vol.88 , pp. 159-166
    • Hishida, A.1    Matsuo, K.2    Hamajima, N.3    Ito, H.4    Ogura, M.5    Kagami, Y.6    Taji, H.7    Morishima, Y.8    Emi, N.9    Tajima, K.10
  • 9
    • 33947596071 scopus 로고    scopus 로고
    • Dietary intake of B-vitamins, polymorphisms in thymidylate synthase and serine hydroxymethyltransferase 1, and colorectal adenoma risk: a Dutch case-control study
    • 10.1016/j.canlet.2006.10.002, 17113224
    • van den Donk M, Visker MH, Harryvan JL, Kok FJ, Kampman E. Dietary intake of B-vitamins, polymorphisms in thymidylate synthase and serine hydroxymethyltransferase 1, and colorectal adenoma risk: a Dutch case-control study. Cancer Lett 2007, 250:146-153. 10.1016/j.canlet.2006.10.002, 17113224.
    • (2007) Cancer Lett , vol.250 , pp. 146-153
    • van den Donk, M.1    Visker, M.H.2    Harryvan, J.L.3    Kok, F.J.4    Kampman, E.5
  • 10
    • 2442681816 scopus 로고    scopus 로고
    • Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study
    • 10.1002/ijc.20148, 15122597
    • Chen J, Kyte C, Valcin M, Chan W, Wetmur JG, Selhub J, Hunter DJ, Ma J. Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. Int J Cancer 2004, 110:617-620. 10.1002/ijc.20148, 15122597.
    • (2004) Int J Cancer , vol.110 , pp. 617-620
    • Chen, J.1    Kyte, C.2    Valcin, M.3    Chan, W.4    Wetmur, J.G.5    Selhub, J.6    Hunter, D.J.7    Ma, J.8
  • 11
    • 55849091713 scopus 로고    scopus 로고
    • Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients
    • Guerreiro CS, Cravo M, Costa AR, Miranda A, Tavares L, Moura-Santos P, MarquesVidal P, Nobre Leitão C. Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients. Am J Clin Nutr 2008, 88:1413-1418.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1413-1418
    • Guerreiro, C.S.1    Cravo, M.2    Costa, A.R.3    Miranda, A.4    Tavares, L.5    Moura-Santos, P.6    MarquesVidal, P.7    Nobre Leitão, C.8
  • 12
    • 45749123112 scopus 로고    scopus 로고
    • Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk
    • 10.1159/000136651, 2758622, 19776626
    • Steck SE, Keku T, Butler LM, Galanko J, Massa B, Millikan RC, Sandler RS. Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk. J Nutrigenet Nutrigenomics 2008, 1:196-204. 10.1159/000136651, 2758622, 19776626.
    • (2008) J Nutrigenet Nutrigenomics , vol.1 , pp. 196-204
    • Steck, S.E.1    Keku, T.2    Butler, L.M.3    Galanko, J.4    Massa, B.5    Millikan, R.C.6    Sandler, R.S.7
  • 14
    • 52549107494 scopus 로고    scopus 로고
    • Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health Study
    • Howard RA, Freedman DM, Park Y, Hollenbeck A, Schatzkin A, Leitzmann MF. Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health Study. Cancer Causes Controls 2008, 19:939-953.
    • (2008) Cancer Causes Controls , vol.19 , pp. 939-953
    • Howard, R.A.1    Freedman, D.M.2    Park, Y.3    Hollenbeck, A.4    Schatzkin, A.5    Leitzmann, M.F.6
  • 17
    • 18544376080 scopus 로고    scopus 로고
    • The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study
    • 10.1158/1055-9965.EPI-04-0840, 15894672
    • Le Marchand L, Wilkens LR, Kolonel LN, Henderson BE. The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 2005, 14:1198-1203. 10.1158/1055-9965.EPI-04-0840, 15894672.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1198-1203
    • Le Marchand, L.1    Wilkens, L.R.2    Kolonel, L.N.3    Henderson, B.E.4
  • 18
    • 7744244730 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea
    • 10.1016/j.canlet.2004.08.014, 15533596
    • Kim DH, Ahn YO, Lee BH, Tsuji E, Kiyohara C, Kono S. Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea. Cancer Lett 2004, 216:199-205. 10.1016/j.canlet.2004.08.014, 15533596.
    • (2004) Cancer Lett , vol.216 , pp. 199-205
    • Kim, D.H.1    Ahn, Y.O.2    Lee, B.H.3    Tsuji, E.4    Kiyohara, C.5    Kono, S.6
  • 20
    • 0032005443 scopus 로고    scopus 로고
    • C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group
    • 10.1016/S0021-9150(97)00237-2, 9543106
    • Gudnason V, Stansbie D, Scott J, Bowron A, Nicaud V, Humphries S. C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group. Atherosclerosis 1998, 136:347-354. 10.1016/S0021-9150(97)00237-2, 9543106.
    • (1998) Atherosclerosis , vol.136 , pp. 347-354
    • Gudnason, V.1    Stansbie, D.2    Scott, J.3    Bowron, A.4    Nicaud, V.5    Humphries, S.6
  • 21
    • 0842281432 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate deficient population
    • 10.1016/j.cccn.2003.09.016, 14734201
    • Pereira AC, Schettert IT, Morandini AAF, Guerra-Shinohara EM, Krieger JE. Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate deficient population. Clin Chim Acta 2004, 340:99-105. 10.1016/j.cccn.2003.09.016, 14734201.
    • (2004) Clin Chim Acta , vol.340 , pp. 99-105
    • Pereira, A.C.1    Schettert, I.T.2    Morandini, A.A.F.3    Guerra-Shinohara, E.M.4    Krieger, J.E.5
  • 22
    • 0036305521 scopus 로고    scopus 로고
    • Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms
    • Bailey LB, Duhaney RL, Maneval DR, Kauwell GP, Quinlivan EP, Davis SR, Cuadras A, Hutson AD, Gregory JF. Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms. J Nutr 2002, 132:1872-1878.
    • (2002) J Nutr , vol.132 , pp. 1872-1878
    • Bailey, L.B.1    Duhaney, R.L.2    Maneval, D.R.3    Kauwell, G.P.4    Quinlivan, E.P.5    Davis, S.R.6    Cuadras, A.7    Hutson, A.D.8    Gregory, J.F.9
  • 23
    • 0036739683 scopus 로고    scopus 로고
    • Influence of age, sex and vitamin status on fasting and post-methionine load plasma homocysteine levels
    • Sassi S, Cosmi B, Palareti G, Legnani C, Grossi G, Musolesi S, Coccheri S. Influence of age, sex and vitamin status on fasting and post-methionine load plasma homocysteine levels. Haematologica 2002, 87:957-964.
    • (2002) Haematologica , vol.87 , pp. 957-964
    • Sassi, S.1    Cosmi, B.2    Palareti, G.3    Legnani, C.4    Grossi, G.5    Musolesi, S.6    Coccheri, S.7
  • 25
    • 0036841514 scopus 로고    scopus 로고
    • Relationship of renal function to homocystein and lipoprotein(a) levels: The frequency of the combination of both risk factors in chronic renal impairment
    • 10.1053/ajkd.2002.36321, 12407635
    • Parsons DS, Reaveley DA, Pavitt DV, Brown EA. Relationship of renal function to homocystein and lipoprotein(a) levels: The frequency of the combination of both risk factors in chronic renal impairment. Am J Kidney Dis 2002, 40:916-923. 10.1053/ajkd.2002.36321, 12407635.
    • (2002) Am J Kidney Dis , vol.40 , pp. 916-923
    • Parsons, D.S.1    Reaveley, D.A.2    Pavitt, D.V.3    Brown, E.A.4
  • 26
    • 11044223935 scopus 로고    scopus 로고
    • Homocysteine: exploring its potential as a pharmacodynamic biomarker of antifolate chemotherapy
    • 10.1517/14622416.5.8.1151, 15584881
    • Valik D, Radina M, Sterba J, Vojtesek B. Homocysteine: exploring its potential as a pharmacodynamic biomarker of antifolate chemotherapy. Pharmacogenomics 2004, 5:1151-1162. 10.1517/14622416.5.8.1151, 15584881.
    • (2004) Pharmacogenomics , vol.5 , pp. 1151-1162
    • Valik, D.1    Radina, M.2    Sterba, J.3    Vojtesek, B.4
  • 27
    • 0036294472 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker
    • 10.1016/S0009-8981(02)00174-2, 12104077
    • Wu LL, Wu JT. Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker. Clin Chim Acta 2002, 322:21-28. 10.1016/S0009-8981(02)00174-2, 12104077.
    • (2002) Clin Chim Acta , vol.322 , pp. 21-28
    • Wu, L.L.1    Wu, J.T.2
  • 28
    • 0038798681 scopus 로고    scopus 로고
    • Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis
    • 10.1038/sj.onc.1206440, 12789261
    • Oikawa S, Murakami K, Kawanishi S. Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis. Oncogene 2003, 22:3530-3538. 10.1038/sj.onc.1206440, 12789261.
    • (2003) Oncogene , vol.22 , pp. 3530-3538
    • Oikawa, S.1    Murakami, K.2    Kawanishi, S.3
  • 30
    • 37549071382 scopus 로고    scopus 로고
    • Simple formulas for gauging the potential impacts of population stratification bias
    • 10.1093/aje/kwm257, 17881384
    • Lee WC, Wang LY. Simple formulas for gauging the potential impacts of population stratification bias. Am J Epidemiol 2007, 167:86-89. 10.1093/aje/kwm257, 17881384.
    • (2007) Am J Epidemiol , vol.167 , pp. 86-89
    • Lee, W.C.1    Wang, L.Y.2
  • 31
    • 77958151930 scopus 로고    scopus 로고
    • Database of Single Nucleotide Polymorphisms (dbSNP). Bethesda (MD): National Center for Biotechnology Information, National Library of Medicine
    • Database of Single Nucleotide Polymorphisms (dbSNP). Bethesda (MD): National Center for Biotechnology Information, National Library of Medicine. dbSNP accession: {rs1979277 and rs1801133}, (dbSNP Build ID: 129) , http://www.ncbi.nlm.nih.gov/SNP/
    • dbSNP accession: {rs1979277 and rs1801133}, (dbSNP Build ID: 129)
  • 32
    • 0003700872 scopus 로고    scopus 로고
    • GLOBOCAN 2002: Cancer incidences, mortality and prevalence worldwide. IARC Cancer Base No. 5 version 2.0
    • Lyon, France: IARC Press
    • Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002: Cancer incidences, mortality and prevalence worldwide. IARC Cancer Base No. 5 version 2.0. 2004, Lyon, France: IARC Press.
    • (2004)
    • Ferlay, J.1    Bray, F.2    Pisani, P.3    Parkin, D.M.4
  • 33
    • 33846781171 scopus 로고    scopus 로고
    • Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China
    • 10.1007/s10552-006-0097-4, 17206530
    • Wang Y, Guo W, He Y, Chen Z, Wen D, Zhang X, Wang N, Li Y, Ge H, Zhang J. Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China. Cancer Causes Control 2007, 18:143-152. 10.1007/s10552-006-0097-4, 17206530.
    • (2007) Cancer Causes Control , vol.18 , pp. 143-152
    • Wang, Y.1    Guo, W.2    He, Y.3    Chen, Z.4    Wen, D.5    Zhang, X.6    Wang, N.7    Li, Y.8    Ge, H.9    Zhang, J.10
  • 35
    • 33845869785 scopus 로고    scopus 로고
    • Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis
    • 10.1007/s10038-006-0082-5, 17089070
    • Huang Y, Han S, Li Y, Mao Y, Xie Y. Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis. J Hum Genet 2007, 52:73-85. 10.1007/s10038-006-0082-5, 17089070.
    • (2007) J Hum Genet , vol.52 , pp. 73-85
    • Huang, Y.1    Han, S.2    Li, Y.3    Mao, Y.4    Xie, Y.5
  • 37
    • 66149137224 scopus 로고    scopus 로고
    • The MTHFR C677T and ΔDNMT3B C-149T polymorphism confer different risks for right- and left-sided colorectal cancer
    • 10.1002/ijc.24324, 19326430
    • Iacopetta B, Heyworth J, Girschik J, Grieu F, Clayforth C, Fritschi L. The MTHFR C677T and ΔDNMT3B C-149T polymorphism confer different risks for right- and left-sided colorectal cancer. Int J Cancer 2009, 125:84-90. 10.1002/ijc.24324, 19326430.
    • (2009) Int J Cancer , vol.125 , pp. 84-90
    • Iacopetta, B.1    Heyworth, J.2    Girschik, J.3    Grieu, F.4    Clayforth, C.5    Fritschi, L.6
  • 38
    • 34547733969 scopus 로고    scopus 로고
    • Age sex and the risk of grade-specific second primary colorectal cancer: Evidence for the protective effect of female hormone
    • 10.1016/j.ejca.2007.05.015, 17604155
    • Liang W. Age sex and the risk of grade-specific second primary colorectal cancer: Evidence for the protective effect of female hormone. Eur J Cancer 2007, 43:1856-1861. 10.1016/j.ejca.2007.05.015, 17604155.
    • (2007) Eur J Cancer , vol.43 , pp. 1856-1861
    • Liang, W.1
  • 40
    • 39649101283 scopus 로고    scopus 로고
    • Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditery nonpoliposis colorectal cancer
    • Talseth BA, Ashton KA, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott RJ. Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditery nonpoliposis colorectal cancer. Int J Cancer 2007, 122:1273-1277.
    • (2007) Int J Cancer , vol.122 , pp. 1273-1277
    • Talseth, B.A.1    Ashton, K.A.2    Meldrum, C.3    Suchy, J.4    Kurzawski, G.5    Lubinski, J.6    Scott, R.J.7
  • 43
    • 0345169186 scopus 로고    scopus 로고
    • The role of genetic factors in the development of hyperhomocysteinemia
    • 10.1515/CCLM.2003.219, 14656021
    • Geisel J, Hübner U, Bodis M, Schorr H, Knapp JP, Obeid R, Herrmann W. The role of genetic factors in the development of hyperhomocysteinemia. Clin Chem Lab Med 2003, 41:1427-1434. 10.1515/CCLM.2003.219, 14656021.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1427-1434
    • Geisel, J.1    Hübner, U.2    Bodis, M.3    Schorr, H.4    Knapp, J.P.5    Obeid, R.6    Herrmann, W.7
  • 44
    • 73249116256 scopus 로고    scopus 로고
    • The effect of MTHFR c.677C > T on plasma homocysteine levels depends on health, age and smoking
    • Semmler A, Moskau S, Stoffel-Wagner B, Weller M, Linnebank M. The effect of MTHFR c.677C > T on plasma homocysteine levels depends on health, age and smoking. Clin Invest Med 2009, 32:E310-E314.
    • (2009) Clin Invest Med , vol.32
    • Semmler, A.1    Moskau, S.2    Stoffel-Wagner, B.3    Weller, M.4    Linnebank, M.5
  • 45
    • 33846539796 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia and immune activation in patients with cancer
    • 10.1515/CCLM.2007.012, 17243914
    • Schroecksnadel K, Frick B, Fiegl M, Winkler C, Denz HA, Fuchs D. Hyperhomocysteinaemia and immune activation in patients with cancer. Clin Chem Lab Med 2007, 45:47-53. 10.1515/CCLM.2007.012, 17243914.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 47-53
    • Schroecksnadel, K.1    Frick, B.2    Fiegl, M.3    Winkler, C.4    Denz, H.A.5    Fuchs, D.6
  • 48
    • 0026096815 scopus 로고
    • Plasma homocysteine in children with acute lymphoblastic leukemia: changes during a chemotherapeutic regimen including methotrexate
    • Refsum H, Wesenberg F, Ueland PM. Plasma homocysteine in children with acute lymphoblastic leukemia: changes during a chemotherapeutic regimen including methotrexate. Cancer Res 1991, 51:828-835.
    • (1991) Cancer Res , vol.51 , pp. 828-835
    • Refsum, H.1    Wesenberg, F.2    Ueland, P.M.3
  • 49
    • 34247149967 scopus 로고    scopus 로고
    • Usefulness of homocysteine as a cancer marker: total thiol compounds and folate levels in untreated lung cancer patients
    • Ozkan Y, Yardim-Akaydin S, Firat H, Calişkan-Can E, Ardiç S, Simşek B. Usefulness of homocysteine as a cancer marker: total thiol compounds and folate levels in untreated lung cancer patients. Anticancer Res 2007, 27:1185-1189.
    • (2007) Anticancer Res , vol.27 , pp. 1185-1189
    • Ozkan, Y.1    Yardim-Akaydin, S.2    Firat, H.3    Calişkan-Can, E.4    Ardiç, S.5    Simşek, B.6
  • 50
    • 33750614452 scopus 로고    scopus 로고
    • Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma
    • Battistelli S, Vittoria A, Stefanoni M, Bing C, Roviello F. Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma. World J Gastroenterol 2006, 12:6128-6132.
    • (2006) World J Gastroenterol , vol.12 , pp. 6128-6132
    • Battistelli, S.1    Vittoria, A.2    Stefanoni, M.3    Bing, C.4    Roviello, F.5
  • 52
    • 77958153156 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C > T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls
    • Zacho J, Yazdanyar S, Bojesen SE, Tybjærg-Hansen A, Nordestgaard BG. Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C > T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls. Int J Cancer 2010,
    • (2010) Int J Cancer
    • Zacho, J.1    Yazdanyar, S.2    Bojesen, S.E.3    Tybjærg-Hansen, A.4    Nordestgaard, B.G.5
  • 54
    • 24644489576 scopus 로고    scopus 로고
    • Diagnostic value of family histories of thrombosis to identify children with thrombophilia
    • 10.1080/08880010591002224, 16169812
    • Ruud E, Holmstrøm H, Brosstad F, Wesenberg F. Diagnostic value of family histories of thrombosis to identify children with thrombophilia. Pediatr Hematol Oncol 2005, 22:453-462. 10.1080/08880010591002224, 16169812.
    • (2005) Pediatr Hematol Oncol , vol.22 , pp. 453-462
    • Ruud, E.1    Holmstrøm, H.2    Brosstad, F.3    Wesenberg, F.4
  • 55
    • 75149138791 scopus 로고    scopus 로고
    • Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin
    • Melichar B, Kalábová H, Krcmová L, Kasparová M, Malírová E, Melicharová K, Pecka M, Hyspler R, Solichová D. Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin. Anticancer Res 2009, 29:4813-4820.
    • (2009) Anticancer Res , vol.29 , pp. 4813-4820
    • Melichar, B.1    Kalábová, H.2    Krcmová, L.3    Kasparová, M.4    Malírová, E.5    Melicharová, K.6    Pecka, M.7    Hyspler, R.8    Solichová, D.9
  • 56
    • 67649225407 scopus 로고    scopus 로고
    • SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis
    • 10.1371/journal.pone.0005839, 2688753, 19513116
    • Anderson DD, Stover PJ. SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. PLoS ONE 2009, 4:e5839. 10.1371/journal.pone.0005839, 2688753, 19513116.
    • (2009) PLoS ONE , vol.4
    • Anderson, D.D.1    Stover, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.