-
1
-
-
47749148805
-
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
-
Cha S.K., Ortega B., Kurosu H., Rosenblatt K.P., Kuro-O M., Huang C.L., et al. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci U S A 2008, 105:9805-9810.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9805-9810
-
-
Cha, S.K.1
Ortega, B.2
Kurosu, H.3
Rosenblatt, K.P.4
Kuro-O, M.5
Huang, C.L.6
-
2
-
-
27144440831
-
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
-
Chang Q., Hoefs S., van der Kemp A.W., Topala C.N., Bindels R.J., Hoenderop J.G., et al. The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005, 310:490-493.
-
(2005)
Science
, vol.310
, pp. 490-493
-
-
Chang, Q.1
Hoefs, S.2
van der Kemp, A.W.3
Topala, C.N.4
Bindels, R.J.5
Hoenderop, J.G.6
-
3
-
-
38049144010
-
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
-
Chen C.D., Podvin S., Gillespie E., Leeman S.E., Abraham C.R. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proc Natl Acad Sci U S A 2007, 104:19796-19801.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19796-19801
-
-
Chen, C.D.1
Podvin, S.2
Gillespie, E.3
Leeman, S.E.4
Abraham, C.R.5
-
4
-
-
84859259028
-
Validation of an immunoassay for soluble klotho protein: decreased levels in diabetes and increased levels in chronic kidney disease
-
Devaraj S., Syed B., Chien A., Jialal I. Validation of an immunoassay for soluble klotho protein: decreased levels in diabetes and increased levels in chronic kidney disease. Am J Clin Pathol 2012, 137:479-485.
-
(2012)
Am J Clin Pathol
, vol.137
, pp. 479-485
-
-
Devaraj, S.1
Syed, B.2
Chien, A.3
Jialal, I.4
-
5
-
-
84880702827
-
The oslo health study: a dietary index estimating frequent intake of soft drinks and rare intake of fruit and vegetables is negatively associated with bone mineral density
-
Hostmark A.T., Sogaard A.J., Alvaer K., Meyer H.E. The oslo health study: a dietary index estimating frequent intake of soft drinks and rare intake of fruit and vegetables is negatively associated with bone mineral density. J Osteoporos 2011, 2011:102686.
-
(2011)
J Osteoporos
, vol.2011
, pp. 102686
-
-
Hostmark, A.T.1
Sogaard, A.J.2
Alvaer, K.3
Meyer, H.E.4
-
6
-
-
84859522038
-
-
Landes Bioscience and Springer Science+Business Media, M. Kuro-o (Ed.)
-
Hu M.C., Kuro-o M., Moe O.W. Endocrine FGFs and Klothos 2012, 126-157. Landes Bioscience and Springer Science+Business Media. M. Kuro-o (Ed.).
-
(2012)
Endocrine FGFs and Klothos
, pp. 126-157
-
-
Hu, M.C.1
Kuro-o, M.2
Moe, O.W.3
-
7
-
-
78651408919
-
Klotho deficiency causes vascular calcification in chronic kidney disease
-
Hu M.C., Shi M., Zhang J., Quiñones H., Griffith C., Kuro-O M., et al. Klotho deficiency causes vascular calcification in chronic kidney disease. J Am Soc Nephrol 2011, 22:124-136.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 124-136
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
Quiñones, H.4
Griffith, C.5
Kuro-O, M.6
-
8
-
-
22244464849
-
Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression
-
Imai M., Ishikawa K., Matsukawa N., Kida I., Ohta J., Ikushima M., et al. Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression. Endocrine 2004, 25:229-234.
-
(2004)
Endocrine
, vol.25
, pp. 229-234
-
-
Imai, M.1
Ishikawa, K.2
Matsukawa, N.3
Kida, I.4
Ohta, J.5
Ikushima, M.6
-
9
-
-
2342610541
-
Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane
-
Imura A., Iwano A., Tohyama O., Tsuji Y., Nozaki K., Hashimoto N., et al. Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane. FEBS Lett 2004, 565:143-147.
-
(2004)
FEBS Lett
, vol.565
, pp. 143-147
-
-
Imura, A.1
Iwano, A.2
Tohyama, O.3
Tsuji, Y.4
Nozaki, K.5
Hashimoto, N.6
-
10
-
-
84870583397
-
Effects of cinacalcet treatment on serum soluble Klotho levels in haemodialysis patients with secondary hyperparathyroidism
-
Komaba H., Koizumi M., Tanaka H., Takahashi H., Sawada K., Kakuta T., et al. Effects of cinacalcet treatment on serum soluble Klotho levels in haemodialysis patients with secondary hyperparathyroidism. Nephrol Dial Transplant 2012, 27:1967-1969.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 1967-1969
-
-
Komaba, H.1
Koizumi, M.2
Tanaka, H.3
Takahashi, H.4
Sawada, K.5
Kakuta, T.6
-
11
-
-
84859553676
-
Klotho and betaKlotho
-
Kuro O. Klotho and betaKlotho. Adv Exp Med Biol 2012, 728:25-40.
-
(2012)
Adv Exp Med Biol
, vol.728
, pp. 25-40
-
-
Kuro, O.1
-
12
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu H., Fergusson M.M., Castilho R.M., Liu J., Cao L., Chen J., et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 2007, 317:803-806.
-
(2007)
Science
, vol.317
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
Liu, J.4
Cao, L.5
Chen, J.6
-
13
-
-
0032567647
-
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
-
Matsumura Y., Aizawa H., Shiraki-Iida T., Nagai R., Kuro-O M., Nabeshima Y.I., et al. Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein. Biochem Biophys Res Commun 1998, 242:626-630.
-
(1998)
Biochem Biophys Res Commun
, vol.242
, pp. 626-630
-
-
Matsumura, Y.1
Aizawa, H.2
Shiraki-Iida, T.3
Nagai, R.4
Kuro-O, M.5
Nabeshima, Y.I.6
-
14
-
-
0032578906
-
Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress
-
Ohyama Y., Kurabayashi M., Masuda H., Nakamura T., Aihara Y., Kaname T., et al. Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress. Biochem Biophys Res Commun 1998, 251:920-925.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 920-925
-
-
Ohyama, Y.1
Kurabayashi, M.2
Masuda, H.3
Nakamura, T.4
Aihara, Y.5
Kaname, T.6
-
15
-
-
0032489424
-
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
-
Shiraki-Iida T., Aizawa H., Matsumura Y., Sekine S., Iida A., Anazawa H., et al. Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 1998, 424:6-10.
-
(1998)
FEBS Lett
, vol.424
, pp. 6-10
-
-
Shiraki-Iida, T.1
Aizawa, H.2
Matsumura, Y.3
Sekine, S.4
Iida, A.5
Anazawa, H.6
-
16
-
-
80755188093
-
Circulating levels of soluble alpha-Klotho in patients with chronic kidney disease
-
Sugiura H., Tsuchiya K., Nitta K. Circulating levels of soluble alpha-Klotho in patients with chronic kidney disease. Clin Exp Nephrol 2011, 15:795-796.
-
(2011)
Clin Exp Nephrol
, vol.15
, pp. 795-796
-
-
Sugiura, H.1
Tsuchiya, K.2
Nitta, K.3
-
17
-
-
0033812019
-
Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging
-
Utsugi T., Ohno T., Ohyama Y., Uchiyama T., Saito Y., Matsumara H., et al. Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging. Metabolism 2000, 49:1118-1123.
-
(2000)
Metabolism
, vol.49
, pp. 1118-1123
-
-
Utsugi, T.1
Ohno, T.2
Ohyama, Y.3
Uchiyama, T.4
Saito, Y.5
Matsumara, H.6
-
18
-
-
77955272026
-
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects
-
Yamazaki Y., Imura A., Urakawa I., Shimada T., Murakami J., Aano Y., et al. Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun 2010, 398:513-518.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 513-518
-
-
Yamazaki, Y.1
Imura, A.2
Urakawa, I.3
Shimada, T.4
Murakami, J.5
Aano, Y.6
-
19
-
-
18744371012
-
Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia
-
Yamazaki Y., Okazaki R., Shibata M., Hasegawa Y., Satoh K., Tajima T., et al. Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia. J Clin Endocrinol Metab 2002, 87:4957-4960.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4957-4960
-
-
Yamazaki, Y.1
Okazaki, R.2
Shibata, M.3
Hasegawa, Y.4
Satoh, K.5
Tajima, T.6
-
20
-
-
0037423695
-
Upregulation of cAMP is a new functional signal pathway of Klotho in endothelial cells
-
Yang J., Matsukawa N., Rakugi H., Imai M., Kida I., Nagai M., et al. Upregulation of cAMP is a new functional signal pathway of Klotho in endothelial cells. Biochem Biophys Res Commun 2003, 301:424-429.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 424-429
-
-
Yang, J.1
Matsukawa, N.2
Rakugi, H.3
Imai, M.4
Kida, I.5
Nagai, M.6
-
21
-
-
84861517705
-
Serum soluble alpha-klotho in hemodialysis patients
-
Yokoyama K., Imura A., Ohkido I., Maruyama Y., Yamazaki Y., Hasegawa H., et al. Serum soluble alpha-klotho in hemodialysis patients. Clin Nephrol 2012, 77:347-351.
-
(2012)
Clin Nephrol
, vol.77
, pp. 347-351
-
-
Yokoyama, K.1
Imura, A.2
Ohkido, I.3
Maruyama, Y.4
Yamazaki, Y.5
Hasegawa, H.6
|