-
1
-
-
0034810211
-
Severely reduced production of klotho in human chronic renal failure kidney
-
Koh N, Fujimori T, Nishiguchi S et al. Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 2001; 280(4):1015-1020
-
(2001)
Biochem Biophys Res Commun
, vol.280
, Issue.4
, pp. 1015-1020
-
-
Koh, N.1
Fujimori, T.2
Nishiguchi, S.3
-
2
-
-
78651408919
-
Klotho deficiency causes vascular calcification in chronic kidney disease
-
Hu MC, Shi M, Zhang J et al. Klotho deficiency causes vascular calcification in chronic kidney disease. J Am Soc Nephrol 2011; 22(1):124-136
-
(2011)
J Am Soc Nephrol
, vol.22
, Issue.1
, pp. 124-136
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
3
-
-
0032575483
-
Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats
-
Aizawa H, Saito Y, Nakamura T et al. Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats. Biochem Biophys Res Commun 1998; 249(3):865-871
-
(1998)
Biochem Biophys Res Commun
, vol.249
, Issue.3
, pp. 865-871
-
-
Aizawa, H.1
Saito, Y.2
Nakamura, T.3
-
4
-
-
0032567647
-
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
-
Matsumura Y, Aizawa H, Shiraki-Iida T et al. Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein. Biochem Biophys Res Commun 1998; 242(3):626-630
-
(1998)
Biochem Biophys Res Commun
, vol.242
, Issue.3
, pp. 626-630
-
-
Matsumura, Y.1
Aizawa, H.2
Shiraki-Iida, T.3
-
5
-
-
0032489424
-
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
-
Shiraki-Iida T, Aizawa H, Matsumura Y et al. Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 1998; 424(1-2):6-10
-
(1998)
FEBS Lett
, vol.424
, Issue.1-2
, pp. 6-10
-
-
Shiraki-Iida, T.1
Aizawa, H.2
Matsumura, Y.3
-
6
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997; 390(6655):45-51
-
(1997)
Nature
, vol.390
, Issue.6655
, pp. 45-51
-
-
Kuro-O, M.1
Matsumura, Y.2
Aizawa, H.3
-
7
-
-
1642352496
-
Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides
-
Tohyama O, Imura A, Iwano A et al. Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides. J Biol Chem 2004; 279(11):9777-9784
-
(2004)
J Biol Chem
, vol.279
, Issue.11
, pp. 9777-9784
-
-
Tohyama, O.1
Imura, A.2
Iwano, A.3
-
8
-
-
38049144010
-
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
-
Chen CD, Podvin S, Gillespie E et al. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proc Natl Acad Sci USA 2007; 104(50):19796-19801
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.50
, pp. 19796-19801
-
-
Chen, C.D.1
Podvin, S.2
Gillespie, E.3
-
9
-
-
70349437179
-
Klotho is a substrate for alpha-, beta- and gamma-secretase
-
Bloch L, Sineshchekova O, Reichenbach D et al. Klotho is a substrate for alpha-, beta- and gamma-secretase. FEBS Lett 2009; 583(19):3221-3224
-
(2009)
FEBS Lett
, vol.583
, Issue.19
, pp. 3221-3224
-
-
Bloch, L.1
Sineshchekova, O.2
Reichenbach, D.3
-
10
-
-
77951871631
-
Regulation of ion channels by secreted Klotho: Mechanisms and implications
-
Huang CL. Regulation of ion channels by secreted Klotho: mechanisms and implications. Kidney Int 2010; 77(10):855-860
-
(2010)
Kidney Int
, vol.77
, Issue.10
, pp. 855-860
-
-
Huang, C.L.1
-
11
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu H, Fergusson MM, Castilho RM et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 2007; 317(5839):803-806
-
(2007)
Science
, vol.317
, Issue.5839
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
-
12
-
-
76249084836
-
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation
-
Goetz R, Nakada Y, Hu MC et al. Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation. Proc Natl Acad SciUSA2010; 107(1):407-412
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.1
, pp. 407-412
-
-
Goetz, R.1
Nakada, Y.2
Hu, M.C.3
-
13
-
-
78049511826
-
Circulating Levels of Soluble Klotho and FGF23 in X-Linked Hypophosphatemia: Circadian Variance, Effects of Treatment and Relationship to Parathyroid Status
-
Carpenter TO, Insogna KL, Zhang JH et al. Circulating Levels of Soluble Klotho and FGF23 in X-Linked Hypophosphatemia: Circadian Variance, Effects of Treatment and Relationship to Parathyroid Status. J Clin Endocrinol Metab 2010; 95(11):E352-E357
-
(2010)
J Clin Endocrinol Metab
, vol.95
, Issue.11
-
-
Carpenter, T.O.1
Insogna, K.L.2
Zhang, J.H.3
-
14
-
-
77956642900
-
Klotho: A novel phosphaturic substance acting as an autocrine enzyme in the renalproximal tubule
-
Hu MC, Shi M, Zhang J et al. Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renalproximal tubule. FASEB J 2010; 24(9):3438-3450
-
(2010)
FASEB J
, vol.24
, Issue.9
, pp. 3438-3450
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
15
-
-
67649834455
-
Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho
-
Cha SK, Hu MC, Kurosu H et al. Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho. Mol Pharmacol 2009; 76(1):38-46
-
(2009)
Mol Pharmacol
, vol.76
, Issue.1
, pp. 38-46
-
-
Cha, S.K.1
Hu, M.C.2
Kurosu, H.3
-
16
-
-
47749148805
-
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
-
Cha SK, Ortega B, Kurosu H et al. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad SciUSA2008; 105(28):9805-9810
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.28
, pp. 9805-9810
-
-
Cha, S.K.1
Ortega, B.2
Kurosu, H.3
-
17
-
-
0034685014
-
Establishment of the anti-Klotho monoclonal antibodies and detection ofKlotho protein in kidneys
-
Kato Y, Arakawa E, Kinoshita S et al. Establishment of the anti-Klotho monoclonal antibodies and detection ofKlotho protein in kidneys. Biochem Biophys Res Commun 2000; 267(2):597-602
-
(2000)
Biochem Biophys Res Commun
, vol.267
, Issue.2
, pp. 597-602
-
-
Kato, Y.1
Arakawa, E.2
Kinoshita, S.3
-
18
-
-
33847781131
-
Amelioration of progressive renal injury by genetic manipulation ofKlotho gene
-
Haruna Y, Kashihara N, Satoh M et al. Amelioration of progressive renal injury by genetic manipulation ofKlotho gene. Proc Natl Acad Sci USA 2007; 104(7):2331-2336
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.7
, pp. 2331-2336
-
-
Haruna, Y.1
Kashihara, N.2
Satoh, M.3
-
19
-
-
0034710838
-
In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome
-
Saito Y, Nakamura T, Ohyama Y et al. In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome. Biochem Biophys Res Commun 2000; 276(2):767-772
-
(2000)
Biochem Biophys Res Commun
, vol.276
, Issue.2
, pp. 767-772
-
-
Saito, Y.1
Nakamura, T.2
Ohyama, Y.3
-
20
-
-
24944481544
-
Suppression of aging in mice by the hormone Klotho
-
Kurosu H, Yamamoto M, Clark JD et al. Suppression of aging in mice by the hormone Klotho. Science 2005; 309(5742):1829-1833
-
(2005)
Science
, vol.309
, Issue.5742
, pp. 1829-1833
-
-
Kurosu, H.1
Yamamoto, M.2
Clark, J.D.3
-
21
-
-
0036235099
-
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage
-
Mitani H, Ishizaka N, Aizawa T et al. In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage. Hypertension 2002; 39(4):838-843
-
(2002)
Hypertension
, vol.39
, Issue.4
, pp. 838-843
-
-
Mitani, H.1
Ishizaka, N.2
Aizawa, T.3
-
22
-
-
23944483457
-
Oxidative stress decreases klotho expression in a mouse kidney cell line
-
Mitobe M, Yoshida T, Sugiura H et al. Oxidative stress decreases klotho expression in a mouse kidney cell line. Nephron Exp Nephrol 2005; 101(2):e67-e74
-
(2005)
Nephron Exp Nephrol
, vol.101
, Issue.2
-
-
Mitobe, M.1
Yoshida, T.2
Sugiura, H.3
-
23
-
-
27944477338
-
Klotho reduces apoptosis in experimental ischaemic acute renal failure
-
Sugiura H, Yoshida T, Tsuchiya K et al. Klotho reduces apoptosis in experimental ischaemic acute renal failure. Nephrol Dial Transplant 2005; 20(12):2636-2645
-
(2005)
Nephrol Dial Transplant
, vol.20
, Issue.12
, pp. 2636-2645
-
-
Sugiura, H.1
Yoshida, T.2
Tsuchiya, K.3
-
24
-
-
27144440831
-
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
-
Chang Q, Hoefs S, van der Kemp AW et al. The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005; 310(5747):490-493
-
(2005)
Science
, vol.310
, Issue.5747
, pp. 490-493
-
-
Chang, Q.1
Hoefs, S.2
Van Der Kemp, A.W.3
-
25
-
-
0036150953
-
Mediation of unusually high concentrations of 1,25-dihydroxy vitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene
-
Yoshida T, Fujimori T, Nabeshima Y. Mediation of unusually high concentrations of 1,25-dihydroxy vitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene. Endocrinology 2002; 143(2):683-689
-
(2002)
Endocrinology
, vol.143
, Issue.2
, pp. 683-689
-
-
Yoshida, T.1
Fujimori, T.2
Nabeshima, Y.3
-
26
-
-
0346849707
-
Klotho, a gene related to a syndrome resemblinghuman premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
-
Tsujikawa H, Kurotaki Y, Fujimori T et al. Klotho, a gene related to a syndrome resemblinghuman premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol 2003; 17(12):2393-2403
-
(2003)
Mol Endocrinol
, vol.17
, Issue.12
, pp. 2393-2403
-
-
Tsujikawa, H.1
Kurotaki, Y.2
Fujimori, T.3
-
27
-
-
77957260363
-
FGF23 and the parathyroid glands
-
Silver J, Naveh-Many T. FGF23 and the parathyroid glands. Pediatr Nephrol 2010; 25(11):2241-2245
-
(2010)
Pediatr Nephrol
, vol.25
, Issue.11
, pp. 2241-2245
-
-
Silver, J.1
Naveh-Many, T.2
-
28
-
-
36849017126
-
The parathyroid is a target organ for FGF23 in rats
-
Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; 117(12):4003-4008
-
(2007)
J Clin Invest
, vol.117
, Issue.12
, pp. 4003-4008
-
-
Ben-Dov, I.Z.1
Galitzer, H.2
Lavi-Moshayoff, V.3
-
29
-
-
73449102873
-
The frequency ofKlotho KL-VS polymorphism in a large Italian population from young subjects to centenarians suggests the presence of specific time windows for its effect
-
Invidia L, Salvioli S, Altilia S et al. The frequency ofKlotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect. Biogerontology2010; 11(1):67-73
-
(2010)
Biogerontology
, vol.11
, Issue.1
, pp. 67-73
-
-
Invidia, L.1
Salvioli, S.2
Altilia, S.3
-
30
-
-
34248587172
-
Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population
-
Zhang F, Zhai G, Kato BS et al. Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population. Osteoarthritis Cartilage 2007
-
(2007)
Osteoarthritis Cartilage
-
-
Zhang, F.1
Zhai, G.2
Kato, B.S.3
-
31
-
-
33748454417
-
The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease
-
Rhee EJ, Oh KW, Lee WY et al. The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease. Metabolism 2006; 55(10):1344-1351
-
(2006)
Metabolism
, vol.55
, Issue.10
, pp. 1344-1351
-
-
Rhee, E.J.1
Oh, K.W.2
Lee, W.Y.3
-
32
-
-
33748997951
-
Relationship between polymorphisms G395A in promoter and C1818T in exon 4 of the KLOTHO gene with glucose metabolism and cardiovascular risk factors in Korean women
-
Rhee EJ, Oh KW, Yun EJ et al. Relationship between polymorphisms G395A in promoter and C1818T in exon 4 of the KLOTHO gene with glucose metabolism and cardiovascular risk factors in Korean women. J Endocrinol Invest 2006; 29(7):613-618
-
(2006)
J Endocrinol Invest
, vol.29
, Issue.7
, pp. 613-618
-
-
Rhee, E.J.1
Oh, K.W.2
Yun, E.J.3
-
33
-
-
33646271370
-
Sickle cell leg ulcers: Associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway
-
Nolan VG, Adewoye A, Baldwin C et al. Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol 2006; 133(5):570-578
-
(2006)
Br J Haematol
, vol.133
, Issue.5
, pp. 570-578
-
-
Nolan, V.G.1
Adewoye, A.2
Baldwin, C.3
-
34
-
-
0038744264
-
KLOTHO allele status and the risk of early-onset occult coronary artery disease
-
Arking DE, Becker DM, Yanek LR et al. KLOTHO allele status and the risk of early-onset occult coronary artery disease. Am J Hum Genet 2003; 72(5):1154-1161
-
(2003)
Am J Hum Genet
, vol.72
, Issue.5
, pp. 1154-1161
-
-
Arking, D.E.1
Becker, D.M.2
Yanek, L.R.3
-
35
-
-
18244372958
-
Association of human aging with a functional variant of klotho
-
Arking DE, Krebsova A, Macek M Sr et al. Association of human aging with a functional variant of klotho. Proc Natl Acad Sci USA 2002; 99(2):856-861
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.2
, pp. 856-861
-
-
Arking, D.E.1
Krebsova, A.2
Macek Sr., M.3
-
36
-
-
0036785320
-
Klotho gene polymorphisms associated with bone density of aged postmenopausal women
-
Kawano K, Ogata N, Chiano M et al. Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res 2002; 17(10):1744-1751
-
(2002)
J Bone Miner Res
, vol.17
, Issue.10
, pp. 1744-1751
-
-
Kawano, K.1
Ogata, N.2
Chiano, M.3
-
37
-
-
72949100508
-
Decreased expression of klotho gene in uremic atherosclerosis in apolipoprotein E-deficient mice
-
Yu J, Deng M, Zhao J et al. Decreased expression of klotho gene in uremic atherosclerosis in apolipoprotein E-deficient mice. Biochem Biophys Res Commun 2010; 391(1):261-266
-
(2010)
Biochem Biophys Res Commun
, vol.391
, Issue.1
, pp. 261-266
-
-
Yu, J.1
Deng, M.2
Zhao, J.3
-
38
-
-
73949135120
-
Klotho variants and chronic hemodialysis mortality
-
Friedman DJ, Afkarian M, Tamez H et al. Klotho variants and chronic hemodialysis mortality. J Bone Miner Res 2009; 24(11):1847-1855
-
(2009)
J Bone Miner Res
, vol.24
, Issue.11
, pp. 1847-1855
-
-
Friedman, D.J.1
Afkarian, M.2
Tamez, H.3
-
39
-
-
0142134263
-
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation ofklotho, an anti-aging gene, in rat
-
Saito K, IshizakaN, Mitani H et al. Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation ofklotho, an anti-aging gene, in rat. FEBS Lett 2003; 551(1-3):58-62
-
(2003)
FEBS Lett
, vol.551
, Issue.1-3
, pp. 58-62
-
-
Saito, K.1
Ishizakan Mitani, H.2
-
40
-
-
77955362051
-
Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats
-
Cheng MF, Chen LJ, Cheng JT. Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats. J Biomed Biotechnol 2010; 2010:513853
-
(2010)
J Biomed Biotechnol
, vol.2010
, pp. 513853
-
-
Cheng, M.F.1
Chen, L.J.2
Cheng, J.T.3
-
41
-
-
77954959800
-
Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression ofKLOTHO an antiaging gene
-
Han DH, Piao SG, Song JH et al. Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression ofKLOTHO, an antiaging gene. Transplantation 2010; 90(2):135-141
-
(2010)
Transplantation
, vol.90
, Issue.2
, pp. 135-141
-
-
Han, D.H.1
Piao, S.G.2
Song, J.H.3
-
42
-
-
79952167540
-
Angiotensin II blockade upregulates the expression ofKlotho the anti-ageing gene in an experimental model of chronic cyclosporine nephropathy
-
Yoon HE, Ghee JY, Piao S et al. Angiotensin II blockade upregulates the expression ofKlotho the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy. Nephrol Dial Transplant 2011; 26(3):800-813
-
(2011)
Nephrol Dial Transplant
, vol.26
, Issue.3
, pp. 800-813
-
-
Yoon, H.E.1
Ghee, J.Y.2
Piao, S.3
-
43
-
-
77955272026
-
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects
-
Yamazaki Y, Imura A, Urakawa I et al. Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun 2010; 398(3):513-518
-
(2010)
Biochem Biophys Res Commun
, vol.398
, Issue.3
, pp. 513-518
-
-
Yamazaki, Y.1
Imura, A.2
Urakawa, I.3
-
44
-
-
80052320047
-
Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production
-
Epub ahead of press
-
Zuo Z, Lei H, Wang X et al. Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production. Age (Dordr) 2010; Epub ahead of press
-
(2010)
Age (Dordr)
-
-
Zuo, Z.1
Lei, H.2
Wang, X.3
-
45
-
-
34848871595
-
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis
-
Ichikawa S, Imel EA, Kreiter ML et al. A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. J Clin Invest 2007; 117(9):2684-2691
-
(2007)
J Clin Invest
, vol.117
, Issue.9
, pp. 2684-2691
-
-
Ichikawa, S.1
Imel, E.A.2
Kreiter, M.L.3
-
47
-
-
42149130855
-
A translocation causing increased alpha-klotho level results inhypophosphatemic rickets and hyperparathyroidism
-
Brownstein CA, Adler F, Nelson-Williams C et al. A translocation causing increased alpha-klotho level results inhypophosphatemic rickets and hyperparathyroidism. Proc Natl Acad Sci USA 2008; 105(9):3455-3460
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.9
, pp. 3455-3460
-
-
Brownstein, C.A.1
Adler, F.2
Nelson-Williams, C.3
-
48
-
-
2342599742
-
Sinoatrial node dysfunction and early unexpected death of mice with a defect ofklotho gene expression
-
Takeshita K, Fujimori T, Kurotaki Y et al. Sinoatrial node dysfunction and early unexpected death of mice with a defect ofklotho gene expression. Circulation 2004; 109(14):1776-1782
-
(2004)
Circulation
, vol.109
, Issue.14
, pp. 1776-1782
-
-
Takeshita, K.1
Fujimori, T.2
Kurotaki, Y.3
-
49
-
-
2342610541
-
Secreted Klotho protein in sera and CSF: Implication for posttranslational cleavage in release ofKlotho protein from cell membrane
-
Imura A, Iwano A, Tohyama O et al. Secreted Klotho protein in sera and CSF: implication for posttranslational cleavage in release ofKlotho protein from cell membrane. FEBS Lett 2004; 565(1-3):143-147
-
(2004)
FEBS Lett
, vol.565
, Issue.1-3
, pp. 143-147
-
-
Imura, A.1
Iwano, A.2
Tohyama, O.3
-
50
-
-
78649642147
-
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective
-
Hu MC, Shi M, Zhang J et al. Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int 2010; 78 (12):1240-1251
-
(2010)
Kidney Int
, vol.78
, Issue.12
, pp. 1240-1251
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
51
-
-
47349116919
-
Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney
-
Schramme A, Abdel-Bakky MS, Gutwein P et al. Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney. Kidney Int 2008; 74(3):328-338
-
(2008)
Kidney Int
, vol.74
, Issue.3
, pp. 328-338
-
-
Schramme, A.1
Abdel-Bakky, M.S.2
Gutwein, P.3
-
52
-
-
40149102029
-
Klotho as a regulator of oxidative stress and senescence
-
Kuro-o M. Klotho as a regulator of oxidative stress and senescence. Biol Chem 2008; 389(3):233-241
-
(2008)
Biol Chem
, vol.389
, Issue.3
, pp. 233-241
-
-
Kuro-O, M.1
-
53
-
-
0026762646
-
Dietary Na age and baroreflex control of heart rate and renal sympathetic nerve activity in rats
-
Huang BS, Leenen FH. Dietary Na, age and baroreflex control of heart rate and renal sympathetic nerve activity in rats. Am J Physiol 1992; 262(5 Pt 2):H1441-H1448
-
(1992)
Am J Physiol
, vol.262
, Issue.5 PART 2
-
-
Huang, B.S.1
Leenen, F.H.2
-
54
-
-
78649862227
-
Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells
-
Yamazaki M, Ozono K, Okada T et al. Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells. J Cell Biochem 2010; 111(5):1210-1221
-
(2010)
J Cell Biochem
, vol.111
, Issue.5
, pp. 1210-1221
-
-
Yamazaki, M.1
Ozono, K.2
Okada, T.3
-
57
-
-
0029793975
-
Ontogeny of the extracellular calcium-sensing receptor in rat kidney
-
Chattopadhyay N, Baum M, Bai M et al. Ontogeny of the extracellular calcium-sensing receptor in rat kidney. Am J Physiol 1996; 271(3 Pt 2):F736-F743
-
(1996)
Am J Physiol
, vol.271
, Issue.3 PART 2
-
-
Chattopadhyay, N.1
Baum, M.2
Bai, M.3
-
58
-
-
64549093430
-
Regulation of phosphate transport in proximal tubules
-
Biber J, Hernando N, Forster I et al. Regulation of phosphate transport in proximal tubules. Pflugers Arch 2009; 458(1):39-52
-
(2009)
Pflugers Arch
, vol.458
, Issue.1
, pp. 39-52
-
-
Biber, J.1
Hernando, N.2
Forster, I.3
-
59
-
-
65949111729
-
PiT-2 coming out of the pits
-
Moe OW. PiT-2 coming out of the pits. Am J Physiol Renal Physiol 2009;296(4):F689-F690
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, Issue.4
-
-
Moe, O.W.1
-
60
-
-
0035166386
-
25-hydroxyvitamin D 1alpha-hydroxylase: Structure of the mouse gene, chromosomal assignment, and developmental expression
-
Panda DK, Al Kawas S, Seldin MF et al. 25-hydroxyvitamin D 1alpha-hydroxylase: structure of the mouse gene, chromosomal assignment, and developmental expression. J Bone Miner Res 2001; 16(1):46-56
-
(2001)
J Bone Miner Res
, vol.16
, Issue.1
, pp. 46-56
-
-
Panda, D.K.1
Al Kawas, S.2
Seldin, M.F.3
-
61
-
-
0041976008
-
Adaptive responses of 25-hydroxyvitamin D3 1-alpha hydroxylase expression to dietary phosphate restriction in young and adult rats
-
Lai WP, Chau TS, Cheung PY et al. Adaptive responses of 25-hydroxyvitamin D3 1-alpha hydroxylase expression to dietary phosphate restriction in young and adult rats. Biochim Biophys Acta 2003; 1639(1):34-42
-
(2003)
Biochim Biophys Acta
, vol.1639
, Issue.1
, pp. 34-42
-
-
Lai, W.P.1
Chau, T.S.2
Cheung, P.Y.3
-
62
-
-
76149101238
-
Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active
-
Shimada T, Urakawa I, Isakova T et al. Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active. J Clin Endocrinol Metab 2010; 95(2):578-585
-
(2010)
J Clin Endocrinol Metab
, vol.95
, Issue.2
, pp. 578-585
-
-
Shimada, T.1
Urakawa, I.2
Isakova, T.3
-
63
-
-
26044452080
-
With or without the kidney: The role of FGF23 in CKD
-
Fukagawa M, Kazama JJ. With or without the kidney: the role of FGF23 in CKD. Nephrol Dial Transplant 2005; 20(7):1295-1298
-
(2005)
Nephrol Dial Transplant
, vol.20
, Issue.7
, pp. 1295-1298
-
-
Fukagawa, M.1
Kazama, J.J.2
-
64
-
-
0141525564
-
Serum FGF23 levels innormal and disordered phosphorus homeostasis
-
Weber TJ, Liu S,Indridason OS etal. SerumFGF23 levels innormal and disordered phosphorus homeostasis. J Bone Miner Res 2003; 18(7):1227-1234
-
(2003)
J Bone Miner Res
, vol.18
, Issue.7
, pp. 1227-1234
-
-
Weber, T.J.1
Liu, S.2
Indridason, O.S.3
-
65
-
-
59649091992
-
In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation ofsystemic phosphate homeostasis
-
Nakatani T, Sarraj B, Ohnishi M et al. In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation ofsystemic phosphate homeostasis. FASEB J2009; 23(2):433-441
-
(2009)
FASEB J
, vol.23
, Issue.2
, pp. 433-441
-
-
Nakatani, T.1
Sarraj, B.2
Ohnishi, M.3
-
66
-
-
33646466978
-
Vascular calcification in chronic kidney disease
-
Jono S, Shioi A, Ikari Y et al. Vascular calcification in chronic kidney disease. J Bone Miner Metab 2006; 24(2):176-181
-
(2006)
J Bone Miner Metab
, vol.24
, Issue.2
, pp. 176-181
-
-
Jono, S.1
Shioi, A.2
Ikari, Y.3
-
67
-
-
0041318888
-
Cardiovascular calcifications in uremic patients: Clinical impact on cardiovascular function
-
London GM. Cardiovascular calcifications in uremic patients: clinical impact on cardiovascular function. J Am Soc Nephrol 2003; 14(9 Suppl 4):S305-S309
-
(2003)
J Am Soc Nephrol
, vol.14
, Issue.9 SUPPL. 4
-
-
London, G.M.1
-
68
-
-
77953724330
-
The aging kidney: Physiological changes
-
Weinstein JR, Anderson S. The aging kidney: physiological changes. Adv Chronic Kidney Dis 2010; 17(4):302-307
-
(2010)
Adv Chronic Kidney Dis
, vol.17
, Issue.4
, pp. 302-307
-
-
Weinstein, J.R.1
Anderson, S.2
-
70
-
-
70249108185
-
Anatomic and physiologic changes of the aging kidney
-
Lerma EV. Anatomic and physiologic changes of the aging kidney. Clin Geriatr Med 2009; 25(3):325-329
-
(2009)
Clin Geriatr Med
, vol.25
, Issue.3
, pp. 325-329
-
-
Lerma, E.V.1
-
71
-
-
35348923554
-
Increased susceptibility of aging kidney to ischemic injury: Identification of candidate genes changed during aging, but corrected by caloric restriction
-
Chen G, Bridenbaugh EA, Akintola AD et al. Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol 2007; 293(4):F1272-F1281
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, Issue.4
-
-
Chen, G.1
Bridenbaugh, E.A.2
Akintola, A.D.3
-
72
-
-
33847412765
-
Acute renal failure in the elderly: Particular characteristics
-
Musso CG, Liakopoulos V, Ioannidis I et al. Acute renal failure in the elderly: particular characteristics. Int Urol Nephrol 2006; 38(3-4):787-793
-
(2006)
Int Urol Nephrol
, vol.38
, Issue.3-4
, pp. 787-793
-
-
Musso, C.G.1
Liakopoulos, V.2
Ioannidis, I.3
-
73
-
-
42249093154
-
Kidney disease in the elderly: Update on recent literature
-
Campbell KH, O'Hare AM. Kidney disease in the elderly: update on recent literature. Curr Opin Nephrol Hypertens 2008; 17(3):298-303
-
(2008)
Curr Opin Nephrol Hypertens
, vol.17
, Issue.3
, pp. 298-303
-
-
Campbell, K.H.1
O'Hare, A.M.2
-
74
-
-
0033863235
-
Massive reduction of urea transporters in remnant kidney and brain of uremic rats
-
Hu MC, Bankir L, Michelet S et al. Massive reduction of urea transporters in remnant kidney and brain of uremic rats. Kidney Int 2000; 58(3):1202-1210
-
(2000)
Kidney Int
, vol.58
, Issue.3
, pp. 1202-1210
-
-
Hu, M.C.1
Bankir, L.2
Michelet, S.3
-
75
-
-
33847275569
-
Prevention of aortic calcification by etidronate in the renal failure rat model
-
Tamura K, Suzuki Y, Matsushita M et al. Prevention of aortic calcification by etidronate in the renal failure rat model. Eur J Pharmacol 2007; 558(1-3):159-166
-
(2007)
Eur J Pharmacol
, vol.558
, Issue.1-3
, pp. 159-166
-
-
Tamura, K.1
Suzuki, Y.2
Matsushita, M.3
-
77
-
-
33845238078
-
Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: Possible contribution of fat-derived factors
-
Nagase M, Yoshida S, Shibata S et al. Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors. J Am Soc Nephrol 2006;17(12):3438-3446
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.12
, pp. 3438-3446
-
-
Nagase, M.1
Yoshida, S.2
Shibata, S.3
-
79
-
-
0026722931
-
Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain
-
Kawano K, Hirashima T, Mori S et al. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes 1992; 41(11):1422-1428
-
(1992)
Diabetes
, vol.41
, Issue.11
, pp. 1422-1428
-
-
Kawano, K.1
Hirashima, T.2
Mori, S.3
-
80
-
-
0035207072
-
Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors
-
Yamagishi T, Saito Y, Nakamura T et al. Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors. Hypertens Res 2001; 24(6):705-709
-
(2001)
Hypertens Res
, vol.24
, Issue.6
, pp. 705-709
-
-
Yamagishi, T.1
Saito, Y.2
Nakamura, T.3
-
81
-
-
0032578906
-
Molecular cloning of rat klotho cDNA: Markedly decreased expression ofklothoby acute inflammatory stress
-
Ohyama Y, Kurabayashi M, Masuda H et al. Molecular cloning of rat klotho cDNA: markedly decreased expression ofklothoby acute inflammatory stress. Biochem Biophys Res Commun 1998;251(3):920-925
-
(1998)
Biochem Biophys Res Commun
, vol.251
, Issue.3
, pp. 920-925
-
-
Ohyama, Y.1
Kurabayashi, M.2
Masuda, H.3
-
82
-
-
77949837759
-
Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis
-
Thurston RD, Larmonier CB, Majewski PM et al. Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis. Gastroenterology 2010; 138(4):1384-1394
-
(2010)
Gastroenterology
, vol.138
, Issue.4
, pp. 1384-1394
-
-
Thurston, R.D.1
Larmonier, C.B.2
Majewski, P.M.3
-
83
-
-
26644469263
-
Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: Meta-analysis and meta-regression of randomised trial data
-
Webster AC, Woodroffe RC, Taylor RS et al. Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. BMJ 2005; 331(7520):810
-
(2005)
BMJ
, vol.331
, Issue.7520
, pp. 810
-
-
Webster, A.C.1
Woodroffe, R.C.2
Taylor, R.S.3
-
84
-
-
0032945772
-
Tacrolimus versus cyclosporin A: A comparative study onrat renal allograft survival
-
Jiang H, Sakuma S, Fujii Y et al. Tacrolimus versus cyclosporin A: a comparative study onrat renal allograft survival. Transpl Int 1999; 12(2):92-99
-
(1999)
Transpl Int
, vol.12
, Issue.2
, pp. 92-99
-
-
Jiang, H.1
Sakuma, S.2
Fujii, Y.3
-
85
-
-
42449092523
-
Tacrolimus: A new therapy for steroid-resistant nephrotic syndrome in children
-
Gulati S, Prasad N, Sharma RK et al. Tacrolimus: a new therapy for steroid-resistant nephrotic syndrome in children. Nephrol Dial Transplant 2008; 23(3):910-913
-
(2008)
Nephrol Dial Transplant
, vol.23
, Issue.3
, pp. 910-913
-
-
Gulati, S.1
Prasad, N.2
Sharma, R.K.3
-
86
-
-
2142715860
-
Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome
-
Tang S, Tang AW, Tam MK et al. Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. Am J Kidney Dis 2003; 42(5):E13-E15
-
(2003)
Am J Kidney Dis
, vol.42
, Issue.5
-
-
Tang, S.1
Tang, A.W.2
Tam, M.K.3
-
87
-
-
10744222215
-
Renal function after liver transplantation: Calcineurin inhibitor nephrotoxicity
-
Ziolkowski J, Paczek L, Senatorski G et al. Renal function after liver transplantation: calcineurin inhibitor nephrotoxicity. Transplant Proc 2003; 35(6):2307-2309
-
(2003)
Transplant Proc
, vol.35
, Issue.6
, pp. 2307-2309
-
-
Ziolkowski, J.1
Paczek, L.2
Senatorski, G.3
-
89
-
-
0038298957
-
Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation
-
Formica RN Jr, Lorber KM, Friedman AL et al. Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation. Transplant Proc 2003; 35(3 Suppl):95S-98S
-
(2003)
Transplant Proc
, vol.35
, Issue.3 SUPPL.
-
-
Formica Jr., R.N.1
Lorber, K.M.2
Friedman, A.L.3
-
90
-
-
20544433192
-
Serum phosphate levels and mortality risk among people with chronic kidney disease
-
Kestenbaum B, Sampson JN, Rudser KD et al. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 2005; 16(2):520-528
-
(2005)
J Am Soc Nephrol
, vol.16
, Issue.2
, pp. 520-528
-
-
Kestenbaum, B.1
Sampson, J.N.2
Rudser, K.D.3
-
91
-
-
0036408913
-
Hyperphosphataemia as a cardiovascular risk factor - How to manage the problem
-
Cannata-Andia JB, Rodriguez-Garcia M. Hyperphosphataemia as a cardiovascular risk factor - how to manage the problem. Nephrol Dial Transplant 2002; 17 Suppl 11:16-19
-
(2002)
Nephrol Dial Transplant
, Issue.17 SUPPL. 11
, pp. 16-19
-
-
Cannata-Andia, J.B.1
Rodriguez-Garcia, M.2
-
92
-
-
59949084660
-
Phosphorus binders and survival on hemodialysis
-
Isakova T, Gutierrez OM, Chang Y et al. Phosphorus binders and survival on hemodialysis. J Am Soc Nephrol 2009; 20(2):388-396
-
(2009)
J Am Soc Nephrol
, vol.20
, Issue.2
, pp. 388-396
-
-
Isakova, T.1
Gutierrez, O.M.2
Chang, Y.3
-
93
-
-
77952544259
-
A potential link between phosphate and aging-lessons from Klotho-deficient mice
-
Kuro-o M. A potential link between phosphate and aging-lessons from Klotho-deficient mice. Mech Ageing Dev 2010; 131(4):270-275
-
(2010)
Mech Ageing Dev
, vol.131
, Issue.4
, pp. 270-275
-
-
Kuro-O, M.1
-
94
-
-
0035208924
-
The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc
-
Morishita K, Shirai A, Kubota M et al. The progression of aging in klotho mutant mice can be modified bydietaryphosphorusandzinc. JNutr2001; 131(12):3182-3188
-
(2001)
J Nutr
, vol.131
, Issue.12
, pp. 3182-3188
-
-
Morishita, K.1
Shirai, A.2
Kubota, M.3
-
95
-
-
0034889433
-
Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications
-
Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001; 22(4):477-501
-
(2001)
Endocr Rev
, vol.22
, Issue.4
, pp. 477-501
-
-
Lips, P.1
-
96
-
-
77957305882
-
Fibroblast growth factor 23 and disordered vitamin D metabolism in chronic kidney disease: Updating the trade-off hypothesis
-
Gutierrez OM. Fibroblast growth factor 23 and disordered vitamin D metabolism in chronic kidney disease: updating the trade-off hypothesis. Clin J Am Soc Nephrol 2010; 5(9):1710-1716
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, Issue.9
, pp. 1710-1716
-
-
Gutierrez, O.M.1
-
97
-
-
33646367420
-
Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
-
Liu S, Tang W, Zhou J et al. Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 2006; 17(5):1305-1315
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.5
, pp. 1305-1315
-
-
Liu, S.1
Tang, W.2
Zhou, J.3
-
98
-
-
77955352430
-
Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress
-
Palm F, Nangaku M, Fasching A et al. Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress. Am J Physiol Renal Physiol 2010; 299(2):F380-F386
-
(2010)
Am J Physiol Renal Physiol
, vol.299
, Issue.2
-
-
Palm, F.1
Nangaku, M.2
Fasching, A.3
-
99
-
-
77952957963
-
Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats3
-
Polichnowski AJ, Jin C, Yang C et al. Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats. Hypertension 2010; 55(6):1425-1430
-
(2010)
Hypertension
, vol.55
, Issue.6
, pp. 1425-1430
-
-
Polichnowski, A.J.1
Jin, C.2
Yang, C.3
-
100
-
-
79251528072
-
Indoxyl Sulfate-Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress
-
Yu M, Kim YJ, Kang DH. Indoxyl Sulfate-Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress. Clin J Am Soc Nephrol 2011: 6(1):30-39
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, Issue.1
, pp. 30-39
-
-
Yu, M.1
Kim, Y.J.2
Kang, D.H.3
-
101
-
-
73349083067
-
Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients
-
Barreto FC, Barreto DV, Liabeuf S et al. Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients. Clin J Am Soc Nephrol 2009; 4(10):1551-1558
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, Issue.10
, pp. 1551-1558
-
-
Barreto, F.C.1
Barreto, D.V.2
Liabeuf, S.3
-
102
-
-
84859780184
-
Indoxyl Sulfate Reduces Klotho Expression and Promotes Senescence in the Kidney ofHypertensive Rats (Abstract)
-
Niwa T, Adijiang A, Higuchi Y et al. Indoxyl Sulfate Reduces Klotho Expression and Promotes Senescence in the Kidney ofHypertensive Rats (Abstract). J Am Soc Nephrol 2010; 21:746A
-
(2010)
J Am Soc Nephrol
, vol.21
-
-
Niwa, T.1
Adijiang, A.2
Higuchi, Y.3
-
103
-
-
34548614821
-
Cyclosporine A induces senescence in renal tubular epithelial cells
-
Jennings P, Koppelstaetter C, Aydin S et al. Cyclosporine A induces senescence in renal tubular epithelial cells. Am J Physiol Renal Physiol 2007; 293(3):F831-F838
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, Issue.3
-
-
Jennings, P.1
Koppelstaetter, C.2
Aydin, S.3
-
104
-
-
34548796464
-
P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury
-
Kailong L, Du X, Yani H et al. P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury. Biocell 2007; 31(2):213-223
-
(2007)
Biocell
, vol.31
, Issue.2
, pp. 213-223
-
-
Kailong, L.1
Du, X.2
Yani, H.3
-
105
-
-
38149103006
-
High NaCl promotes cellular senescence
-
DmitrievaNI, Burg MB. High NaCl promotes cellular senescence. Cell Cycle 2007; 6(24):3108-3113
-
(2007)
Cell Cycle
, vol.6
, Issue.24
, pp. 3108-3113
-
-
Dmitrieva, N.I.1
Burg, M.B.2
-
106
-
-
77956534990
-
Cell senescence in the aging kidney
-
Yang H, Fogo AB. Cell senescence in the aging kidney. J Am Soc Nephrol 2010; 21(9):1436-1439
-
(2010)
J Am Soc Nephrol
, vol.21
, Issue.9
, pp. 1436-1439
-
-
Yang, H.1
Fogo, A.B.2
-
107
-
-
70350438009
-
Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition
-
Nakano-Kurimoto R, Ikeda K, Uraoka M et al. Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition. Am J Physiol Heart Circ Physiol 2009; 297(5):H1673-H1684
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.5
-
-
Nakano-Kurimoto, R.1
Ikeda, K.2
Uraoka, M.3
-
108
-
-
72049124334
-
The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury
-
Yang HC, Deleuze S, Zuo Y et al. The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury. J Am Soc Nephrol 2009; 20(11):2380-2388
-
(2009)
J Am Soc Nephrol
, vol.20
, Issue.11
, pp. 2380-2388
-
-
Yang, H.C.1
Deleuze, S.2
Zuo, Y.3
-
109
-
-
78349295987
-
Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate
-
Shimizu H, Bolati D, Adijiang A et al. Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. Am J Physiol Cell Physiol 2010; 299(5):C1110-C1117
-
(2010)
Am J Physiol Cell Physiol
, vol.299
, Issue.5
-
-
Shimizu, H.1
Bolati, D.2
Adijiang, A.3
-
110
-
-
33749342012
-
Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway
-
De Oliveira RM. Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway. FEBS Lett 2006; 580(24):5753-5758
-
(2006)
FEBS Lett
, vol.580
, Issue.24
, pp. 5753-5758
-
-
De Oliveira, R.M.1
-
111
-
-
28844474827
-
Anti-apoptotic and anti-senescence effects ofKlotho on vascular endothelial cells
-
Ikushima M, Rakugi H, Ishikawa K et al. Anti-apoptotic and anti-senescence effects ofKlotho on vascular endothelial cells. Biochem Biophys Res Commun 2006; 339(3):827-832
-
(2006)
Biochem Biophys Res Commun
, vol.339
, Issue.3
, pp. 827-832
-
-
Ikushima, M.1
Rakugi, H.2
Ishikawa, K.3
-
112
-
-
76349099550
-
Does therapeutic angiogenesis overcome CKD?
-
Taniyama Y, Morishita R. Does therapeutic angiogenesis overcome CKD? Hypertens Res2010;33(2):114-115
-
(2010)
Hypertens Res
, vol.33
, Issue.2
, pp. 114-115
-
-
Taniyama, Y.1
Morishita, R.2
-
113
-
-
58849142993
-
Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism
-
Mu W, Long DA, Ouyang X et al. Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism. Am J Physiol Renal Physiol 2009;296(1):F145-F152
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, Issue.1
-
-
Mu, W.1
Long, D.A.2
Ouyang, X.3
-
114
-
-
34147137277
-
End-stage renal disease causes an imbalance between endothelial and smooth muscle progenitor cells
-
Westerweel PE, Hoefer IE, Blankestijn PJ et al. End-stage renal disease causes an imbalance between endothelial and smooth muscle progenitor cells. Am J Physiol Renal Physiol 2007; 292(4):F1132-F1140
-
(2007)
Am J Physiol Renal Physiol
, vol.292
, Issue.4
-
-
Westerweel, P.E.1
Hoefer, I.E.2
Blankestijn, P.J.3
-
115
-
-
33845673344
-
Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia
-
Chade AR, Zhu X, Mushin OP et al. Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia. FASEB J 2006; 20(10):1706-1708
-
(2006)
FASEB J
, vol.20
, Issue.10
, pp. 1706-1708
-
-
Chade, A.R.1
Zhu, X.2
Mushin, O.P.3
-
116
-
-
33645469671
-
Angiogenesis and endothelial cell repair in renal disease and allograft rejection
-
Reinders ME, Rabelink TJ, Briscoe DM. Angiogenesis and endothelial cell repair in renal disease and allograft rejection. J Am Soc Nephrol 2006; 17(4):932-942
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.4
, pp. 932-942
-
-
Reinders, M.E.1
Rabelink, T.J.2
Briscoe, D.M.3
-
117
-
-
0035986324
-
Production of nitric oxide, but not prostacyclin, is reduced in klotho mice
-
Nakamura T, Saito Y, Ohyama Y et al. Production of nitric oxide, but not prostacyclin, is reduced in klotho mice. Jpn J Pharmacol 2002; 89(2):149-156
-
(2002)
Jpn J Pharmacol
, vol.89
, Issue.2
, pp. 149-156
-
-
Nakamura, T.1
Saito, Y.2
Ohyama, Y.3
-
118
-
-
4944242707
-
Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse
-
Shimada T, Takeshita Y, Murohara T et al. Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse. Circulation 2004; 110(9):1148-1155
-
(2004)
Circulation
, vol.110
, Issue.9
, pp. 1148-1155
-
-
Shimada, T.1
Takeshita, Y.2
Murohara, T.3
-
119
-
-
0036295211
-
Regulation of angiogenesis by the aging suppressor gene klotho
-
Fukino K, Suzuki T, Saito Y et al. Regulation of angiogenesis by the aging suppressor gene klotho. Biochem Biophys Res Commun 2002; 293(1):332-337
-
(2002)
Biochem Biophys Res Commun
, vol.293
, Issue.1
, pp. 332-337
-
-
Fukino, K.1
Suzuki, T.2
Saito, Y.3
-
120
-
-
70149098681
-
Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation
-
Maekawa Y, Ishikawa K, Yasuda O et al. Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation. Endocrine 2009;35(3):341-346
-
(2009)
Endocrine
, vol.35
, Issue.3
, pp. 341-346
-
-
Maekawa, Y.1
Ishikawa, K.2
Yasuda, O.3
-
121
-
-
77955602944
-
Resolved: EMT produces fibroblasts in the kidney
-
Zeisberg M, Duffield JS. Resolved: EMT produces fibroblasts in the kidney. J Am Soc Nephrol 2010; 21(8):1247-1253
-
(2010)
J Am Soc Nephrol
, vol.21
, Issue.8
, pp. 1247-1253
-
-
Zeisberg, M.1
Duffield, J.S.2
-
122
-
-
77949351029
-
New insights into epithelial-mesenchymal transition in kidney fibrosis
-
Liu Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 2010; 21(2):212-222
-
(2010)
J Am Soc Nephrol
, vol.21
, Issue.2
, pp. 212-222
-
-
Liu, Y.1
-
123
-
-
77949391412
-
Parathyroid hormone-related protein promotes epithelial-mesenchymal transition
-
Ardura JA, Rayego-Mateos S, Ramila D et al. Parathyroid hormone-related protein promotes epithelial-mesenchymal transition. J Am Soc Nephrol 2010; 21(2):237-248
-
(2010)
J Am Soc Nephrol
, vol.21
, Issue.2
, pp. 237-248
-
-
Ardura, J.A.1
Rayego-Mateos, S.2
Ramila, D.3
-
124
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112(12):1776-1784
-
(2003)
J Clin Invest
, vol.112
, Issue.12
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
125
-
-
0038717407
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 2003; 9(7):964-968
-
(2003)
Nat Med
, vol.9
, Issue.7
, pp. 964-968
-
-
Zeisberg, M.1
Hanai, J.2
Sugimoto, H.3
-
126
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
Iwano M, Plieth D, DanoffTM et al. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002; 110(3):341-350
-
(2002)
J Clin Invest
, vol.110
, Issue.3
, pp. 341-350
-
-
Iwano, M.1
Plieth, D.2
Danoff, T.M.3
-
127
-
-
77957321319
-
EMT and TGF-beta in renal fibrosis
-
Iwano M. EMT and TGF-beta in renal fibrosis. Front Biosci (Schol Ed) 2010; 2:229-238
-
(2010)
Front Biosci (Schol Ed)
, vol.2
, pp. 229-238
-
-
Iwano, M.1
-
128
-
-
70350545853
-
TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy
-
Hills CE, Squires PE. TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy. AmJNephrol 2010; 31(1):68-74
-
(2010)
Am J Nephrol
, vol.31
, Issue.1
, pp. 68-74
-
-
Hills, C.E.1
Squires, P.E.2
-
129
-
-
0346727324
-
Targeted disruption ofTGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S et al. Targeted disruption ofTGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 2003; 112(10):1486-1494
-
(2003)
J Clin Invest
, vol.112
, Issue.10
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
-
130
-
-
84859738406
-
TGF-p Was Upregulated in Renal Fibrosis Model ofKlotho Defect Mouse and Affected Renal Klotho Expression Level (Abstract)
-
Sugiura H, Yoshida T, Kohei J et al. TGF-p Was Upregulated in Renal Fibrosis Model ofKlotho Defect Mouse and Affected Renal Klotho Expression Level (Abstract). J Am Soc Nephrol 2010; 21:376A
-
(2010)
J Am Soc Nephrol
, vol.21
-
-
Sugiura, H.1
Yoshida, T.2
Kohei, J.3
-
131
-
-
84859781073
-
Secreted Klotho Protein Counteracts Renal Fibrosis through Inhibiting TGF-b1 Signaling (Abstract)
-
Doi S, Yorioka N, Kuroo M. Secreted Klotho Protein Counteracts Renal Fibrosis through Inhibiting TGF-b1 Signaling (Abstract). J Am Soc Nephrol 2010; 21:270A
-
(2010)
J Am Soc Nephrol
, vol.21
-
-
Doi, S.1
Yorioka, N.2
Kuroo, M.3
-
132
-
-
0030882822
-
The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/ procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis
-
Yamamoto K, Loskutoff DJ. The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/ procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis. Am J Pathol 1997; 151(3):725-734
-
(1997)
Am J Pathol
, vol.151
, Issue.3
, pp. 725-734
-
-
Yamamoto, K.1
Loskutoff, D.J.2
-
133
-
-
0031815362
-
Renal expression of fibrinolytic genes and tissue factor in a murine model of renal disease as a function of age
-
Yamamoto K, Loskutoff DJ, Saito H. Renal expression of fibrinolytic genes and tissue factor in a murine model of renal disease as a function of age. Semin Thromb Hemost 1998; 24(3):261-268
-
(1998)
Semin Thromb Hemost
, vol.24
, Issue.3
, pp. 261-268
-
-
Yamamoto, K.1
Loskutoff, D.J.2
Saito, H.3
-
134
-
-
33750716519
-
Plasminogen activator inhibitor-1 in chronic kidney disease: Evidence and mechanisms of action
-
Eddy AA, Fogo AB. Plasminogen activator inhibitor-1 in chronic kidney disease: evidence and mechanisms of action. J Am Soc Nephrol 2006; 17(11):2999-3012
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.11
, pp. 2999-3012
-
-
Eddy, A.A.1
Fogo, A.B.2
-
135
-
-
12244263052
-
Increased expression ofplasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging Klotho mouse
-
TakeshitaK, Yamamoto K, ItoM etal. Increased expression ofplasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, Klotho mouse. Semin Thromb Hemost 2002; 28(6):545-554
-
(2002)
Semin Thromb Hemost
, vol.28
, Issue.6
, pp. 545-554
-
-
Takeshita, K.1
Yamamoto, K.2
Ito, M.3
-
136
-
-
39049096394
-
Mechanisms of vascular calcification in chronic kidney disease
-
Moe SM, Chen NX. Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol 2008; 19(2):213-216
-
(2008)
J Am Soc Nephrol
, vol.19
, Issue.2
, pp. 213-216
-
-
Moe, S.M.1
Chen, N.X.2
-
137
-
-
33845274560
-
Vascular calcifications: Pathogenesis, management, and impact on clinical outcomes
-
Cannata-Andia JB, Rodriguez-Garcia M, Carrillo-Lopez N et al. Vascular calcifications: pathogenesis, management, and impact on clinical outcomes. J Am Soc Nephrol 2006; 17(12 Suppl 3):S267-S273
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.12 SUPPL. 3
-
-
Cannata-Andia, J.B.1
Rodriguez-Garcia, M.2
Carrillo-Lopez, N.3
-
138
-
-
67649678424
-
Vascular calcification: The killer of patients with chronic kidney disease
-
Mizobuchi M, Towler D, Slatopolsky E. Vascular calcification: the killer of patients with chronic kidney disease. J Am Soc Nephrol 2009; 20(7):1453-1464
-
(2009)
J Am Soc Nephrol
, vol.20
, Issue.7
, pp. 1453-1464
-
-
Mizobuchi, M.1
Towler, D.2
Slatopolsky, E.3
-
139
-
-
33646157733
-
Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
-
Li X, Yang HY, Giachelli CM. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 2006; 98(7):905-912
-
(2006)
Circ Res
, vol.98
, Issue.7
, pp. 905-912
-
-
Li, X.1
Yang, H.Y.2
Giachelli, C.M.3
-
140
-
-
84859753990
-
Development ofKlotho-FGFR1/3 Dependent Resistance to FGF-23 in Human Aortic Smooth Muscle Cells Exposed to Calcifying Stress
-
Lim K,LuT-S, Zehnder D et al. Development ofKlotho-FGFR1/3 Dependent Resistance to FGF-23 in Human Aortic Smooth Muscle Cells Exposed to Calcifying Stress. J Am Soc Nephrol 2010; 21:140A
-
(2010)
J Am Soc Nephrol
, vol.21
-
-
Lim, K.1
Lu, T.-S.2
Zehnder, D.3
-
141
-
-
0024417103
-
Contributive factors to cardiovascular hypertrophy in renal failure
-
London GM, Marchais SJ, Guerin AP et al. Contributive factors to cardiovascular hypertrophy in renal failure. Am J Hypertens 1989; 2(11 Pt 2):261S-263S
-
(1989)
Am J Hypertens
, vol.2
, Issue.11 PART 2
-
-
London, G.M.1
Marchais, S.J.2
Guerin, A.P.3
-
142
-
-
33646799099
-
Cardiovascular disease in the dialysis population: Prognostic significance of arterial disorders
-
Guerin AP, Pannier B, Marchais SJ et al. Cardiovascular disease in the dialysis population: prognostic significance of arterial disorders. Curr Opin Nephrol Hypertens 2006; 15(2):105-110
-
(2006)
Curr Opin Nephrol Hypertens
, vol.15
, Issue.2
, pp. 105-110
-
-
Guerin, A.P.1
Pannier, B.2
Marchais, S.J.3
-
143
-
-
78651097847
-
Epidemiology and pathophysiology of left ventricular abnormalities in chronic kidney disease: Areview
-
Cerasola G, Nardi E, Palermo A et al. Epidemiology and pathophysiology of left ventricular abnormalities in chronic kidney disease: areview. JNephrol 2011; 24(1):1-10
-
(2011)
J Nephrol
, vol.24
, Issue.1
, pp. 1-10
-
-
Cerasola, G.1
Nardi, E.2
Palermo, A.3
-
144
-
-
77649199024
-
A comprehensive study of cardiovascular risk factors cardiac function and vascular disease in children with chronic renal failure
-
Rinat C, Becker-Cohen R, Nir A et al. A comprehensive study of cardiovascular risk factors, cardiac function and vascular disease in children with chronic renal failure. Nephrol Dial Transplant 2010; 25(3):785-793
-
(2010)
Nephrol Dial Transplant
, vol.25
, Issue.3
, pp. 785-793
-
-
Rinat, C.1
Becker-Cohen, R.2
Nir, A.3
-
145
-
-
67651048925
-
Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: A randomized controlled trial
-
Edwards NC, Steeds RP, Stewart PM et al. Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. J Am Coll Cardiol 2009; 54(6):505-512
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.6
, pp. 505-512
-
-
Edwards, N.C.1
Steeds, R.P.2
Stewart, P.M.3
-
146
-
-
0030982693
-
Angiotensin II receptor antagonists. Potential in elderly patients with cardiovascular disease
-
Burrell LM, Johnston CI. Angiotensin II receptor antagonists. Potential in elderly patients with cardiovascular disease. DrugsAging 1997; 10(6):421-434
-
(1997)
Drugs Aging
, vol.10
, Issue.6
, pp. 421-434
-
-
Burrell, L.M.1
Johnston, C.I.2
-
147
-
-
24944566874
-
The role of vitamin D in left ventricular hypertrophy and cardiac function
-
Achinger SG, Ayus JC. The role of vitamin D in left ventricular hypertrophy and cardiac function. Kidney Int 2005; 95 Suppl:S37-S42
-
(2005)
Kidney Int
, vol.95
, Issue.SUPPL.
-
-
Achinger, S.G.1
Ayus, J.C.2
-
148
-
-
70450230670
-
Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
-
Mirza MA, Larsson A, Melhus H et al. Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population. Atherosclerosis 2009; 207(2):546-551
-
(2009)
Atherosclerosis
, vol.207
, Issue.2
, pp. 546-551
-
-
Mirza, M.A.1
Larsson, A.2
Melhus, H.3
-
149
-
-
74449094013
-
Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease
-
Galitzer H, Ben-Dov IZ, Silver J et al. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int 2010; 77(3):211-218
-
(2010)
Kidney Int
, vol.77
, Issue.3
, pp. 211-218
-
-
Galitzer, H.1
Ben-Dov, I.Z.2
Silver, J.3
-
150
-
-
34247201550
-
Vitamin D deficiency and secondary hyperparathyroidism among patients with chronic kidney disease
-
Khan S, Vitamin D deficiency and secondary hyperparathyroidism among patients with chronic kidney disease. Am J Med Sci 2007; 333(4):201-207
-
(2007)
Am J Med Sci
, vol.333
, Issue.4
, pp. 201-207
-
-
Khan, S.1
-
151
-
-
78049481921
-
Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients
-
Krajisnik T, Olauson H, Mirza MA et al. Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients. Kidney Int 2010; 78(10):1024-1032
-
(2010)
Kidney Int
, vol.78
, Issue.10
, pp. 1024-1032
-
-
Krajisnik, T.1
Olauson, H.2
Mirza, M.A.3
-
153
-
-
78349310932
-
Increased parathyroid expression of klotho in uremic rats
-
Hofman-Bang J, Martuseviciene G, Santini MA et al. Increased parathyroid expression of klotho in uremic rats. Kidney Int2010; 78(11):1119-1127
-
(2010)
Kidney Int
, vol.78
, Issue.11
, pp. 1119-1127
-
-
Hofman-Bang, J.1
Martuseviciene, G.2
Santini, M.A.3
-
154
-
-
77951259224
-
Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): Implications for disorders of phosphate metabolism
-
Gattineni J, Baum M. Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism. Pediatr Nephrol 2010; 25(4):591-601
-
(2010)
Pediatr Nephrol
, vol.25
, Issue.4
, pp. 591-601
-
-
Gattineni, J.1
Baum, M.2
-
155
-
-
54149083620
-
Bone mineral metabolism and its relationship to kidney disease in a residential care home population: A cross-sectional study
-
Carter JL, O'Riordan SE, Eaglestone GL et al. Bone mineral metabolism and its relationship to kidney disease in a residential care home population: a cross-sectional study. Nephrol Dial Transplant 2008; 23(11):3554-3565
-
(2008)
Nephrol Dial Transplant
, vol.23
, Issue.11
, pp. 3554-3565
-
-
Carter, J.L.1
O'Riordan, S.E.2
Eaglestone, G.L.3
-
156
-
-
77749334660
-
Early control of PTH and FGF23 in normophosphatemic CKD patients: A new target in CKD-MBD therapy?
-
Oliveira RB, Cancela AL, Graciolli FG et al. Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy? Clin J Am Soc Nephrol 2010; 5(2):286-291
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, Issue.2
, pp. 286-291
-
-
Oliveira, R.B.1
Cancela, A.L.2
Graciolli, F.G.3
-
157
-
-
33750993057
-
FGF23: Its role in renal bone disease
-
FukagawaM, Kazama JJ. FGF23: its role in renal bone disease. Pediatr Nephrol 2006; 21(12):1802-1806
-
(2006)
Pediatr Nephrol
, vol.21
, Issue.12
, pp. 1802-1806
-
-
Fukagawa, M.1
Kazama, J.J.2
-
158
-
-
61749096686
-
Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in nondiabetic predialysis CKD patients
-
Tomida K, Hamano T, Mikami S et al. Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in nondiabetic predialysis CKD patients. Bone 2009; 44(4):678-683
-
(2009)
Bone
, vol.44
, Issue.4
, pp. 678-683
-
-
Tomida, K.1
Hamano, T.2
Mikami, S.3
-
159
-
-
33846527154
-
Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: The Rancho Bernardo study
-
Jassal SK, von Muhlen D, Barrett-Connor E. Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: the Rancho Bernardo study. J Bone Miner Res 2007; 22(2):203-210
-
(2007)
J Bone Miner Res
, vol.22
, Issue.2
, pp. 203-210
-
-
Jassal, S.K.1
Von Muhlen, D.2
Barrett-Connor, E.3
-
160
-
-
0032746021
-
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia
-
Kawaguchi H, Manabe N, Miyaura C et al. Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia. J Clin Invest 1999; 104(3):229-237
-
(1999)
J Clin Invest
, vol.104
, Issue.3
, pp. 229-237
-
-
Kawaguchi, H.1
Manabe, N.2
Miyaura, C.3
-
161
-
-
0034091390
-
Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse
-
Kawaguchi H, Manabe N, Chikuda H et al. Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse. Cell Mol Life Sci 2000; 57(5):731-737
-
(2000)
Cell Mol Life Sci
, vol.57
, Issue.5
, pp. 731-737
-
-
Kawaguchi, H.1
Manabe, N.2
Chikuda, H.3
-
162
-
-
0034220058
-
Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene
-
Shiraki-Iida T, Iida A, Nabeshima Y et al. Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene. J Gene Med 2000; 2(4):233-242
-
(2000)
J Gene Med
, vol.2
, Issue.4
, pp. 233-242
-
-
Shiraki-Iida, T.1
Iida, A.2
Nabeshima, Y.3
-
163
-
-
33846867744
-
Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice
-
Segawa H, Yamanaka S, Ohno Y et al. Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice. Am J Physiol Renal Physiol 2007; 292(2):F769-F779
-
(2007)
Am J Physiol Renal Physiol
, vol.292
, Issue.2
-
-
Segawa, H.1
Yamanaka, S.2
Ohno, Y.3
-
164
-
-
0028181761
-
Cloning of a Na/Pi cotransporter from opossum kidney cells
-
Sorribas V, Markovich D, Hayes G et al. Cloning of a Na/Pi cotransporter from opossum kidney cells. J Biol Chem 1994; 269(9):6615-6621
-
(1994)
J Biol Chem
, vol.269
, Issue.9
, pp. 6615-6621
-
-
Sorribas, V.1
Markovich, D.2
Hayes, G.3
-
165
-
-
61549138434
-
Hyperphosphatemia and hyperparathyroidism in incident chronic kidney disease patients
-
Ramos AM, Albalate M, Vazquez S et al. Hyperphosphatemia and hyperparathyroidism in incident chronic kidney disease patients. Kidney Int 2008; 111(Suppl):S88-S93
-
(2008)
Kidney Int
, vol.111
, Issue.SUPPL.
-
-
Ramos, A.M.1
Albalate, M.2
Vazquez, S.3
-
166
-
-
0036374148
-
Role of dietary phosphorus in the progression ofrenal failure
-
Koizumi T, Murakami K, Nakayama H et al. Role of dietary phosphorus in the progression ofrenal failure. Biochem Biophys Res Commun 2002; 295(4):917-921
-
(2002)
Biochem Biophys Res Commun
, vol.295
, Issue.4
, pp. 917-921
-
-
Koizumi, T.1
Murakami, K.2
Nakayama, H.3
-
167
-
-
70449650496
-
Phosphate removal with several thrice-weekly dialysis methods in overweight hemodialysis patients
-
Tonelli M, Wang W, Hemmelgarn B et al. Phosphate removal with several thrice-weekly dialysis methods in overweight hemodialysis patients. Am J Kidney Dis 2009; 54(6):1108-1115
-
(2009)
Am J Kidney Dis
, vol.54
, Issue.6
, pp. 1108-1115
-
-
Tonelli, M.1
Wang, W.2
Hemmelgarn, B.3
-
168
-
-
33845252957
-
Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo
-
Marshall CB, Pippin JW, Krofft RD et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int 2006; 70(11):1962-1973
-
(2006)
Kidney Int
, vol.70
, Issue.11
, pp. 1962-1973
-
-
Marshall, C.B.1
Pippin, J.W.2
Krofft, R.D.3
-
169
-
-
0028520766
-
Reactive oxygen species and progressive glomerular disease
-
Diamond JR. Reactive oxygen species and progressive glomerular disease. J Lab Clin Med 1994; 124(4):468-469
-
(1994)
J Lab Clin Med
, vol.124
, Issue.4
, pp. 468-469
-
-
Diamond, J.R.1
-
170
-
-
33947659941
-
Differential expressions of antioxidant status in aging rats: The role of transcriptional factor Nrf2 and MAPK signaling pathway
-
Shih PH, Yen GC. Differential expressions of antioxidant status in aging rats: the role of transcriptional factor Nrf2 and MAPK signaling pathway. Biogerontology 2007; 8(2):71-80
-
(2007)
Biogerontology
, vol.8
, Issue.2
, pp. 71-80
-
-
Shih, P.H.1
Yen, G.C.2
-
171
-
-
23044504845
-
Genetic influences on oxidative stress and their association with normal cognitive ageing
-
Kachiwala SJ, Harris SE, Wright AF et al. Genetic influences on oxidative stress and their association with normal cognitive ageing. Neurosci Lett 2005; 386(2):116-120
-
(2005)
Neurosci Lett
, vol.386
, Issue.2
, pp. 116-120
-
-
Kachiwala, S.J.1
Harris, S.E.2
Wright, A.F.3
-
172
-
-
27844561111
-
Regulation of oxidative stress by the anti-aging hormone klotho
-
Yamamoto M, Clark JD, Pastor JV et al. Regulation of oxidative stress by the anti-aging hormone klotho. J Biol Chem 2005; 280(45):38029-38034
-
(2005)
J Biol Chem
, vol.280
, Issue.45
, pp. 38029-38034
-
-
Yamamoto, M.1
Clark, J.D.2
Pastor, J.V.3
-
173
-
-
0035874179
-
A new murine oxidative stress model associated with senescence
-
Feng R, He W, Ochi H. A new murine oxidative stress model associated with senescence. Mech Ageing Dev 2001; 122(6):547-559
-
(2001)
Mech Ageing Dev
, vol.122
, Issue.6
, pp. 547-559
-
-
Feng, R.1
He, W.2
Ochi, H.3
-
174
-
-
58049202919
-
Effects of donor age and cell senescence on kidney allograft survival
-
Melk A, Schmidt BM, Braun H et al. Effects of donor age and cell senescence on kidney allograft survival. Am J Transplant 2009; 9(1):114-123
-
(2009)
Am J Transplant
, vol.9
, Issue.1
, pp. 114-123
-
-
Melk, A.1
Schmidt, B.M.2
Braun, H.3
-
175
-
-
77955489258
-
Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition
-
Yang F, Huang XR, Chung AC et al. Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition. J Pathol 2010; 221(4):390-401
-
(2010)
J Pathol
, vol.221
, Issue.4
, pp. 390-401
-
-
Yang, F.1
Huang, X.R.2
Chung, A.C.3
-
176
-
-
33745821648
-
Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth
-
Liang XB, Ma LJ, Naito T et al. Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. J Am Soc Nephrol 2006; 17(7):1886-1895
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.7
, pp. 1886-1895
-
-
Liang, X.B.1
Ma, L.J.2
Naito, T.3
-
177
-
-
0142089093
-
Angiotensin II mediates LDL-induced superoxide generation in mesangial cells
-
Park SY, Song CY, Kim BC et al. Angiotensin II mediates LDL-induced superoxide generation in mesangial cells. Am J Physiol Renal Physiol 2003; 285(5):F909-F915
-
(2003)
Am J Physiol Renal Physiol
, vol.285
, Issue.5
-
-
Park, S.Y.1
Song, C.Y.2
Kim, B.C.3
-
178
-
-
0033711173
-
Angiotensin II infused intrarenally causes preglomerular vascular changes and hypertension
-
Stevenson KM, Edgley AJ, Bergstrom G et al. Angiotensin II infused intrarenally causes preglomerular vascular changes and hypertension. Hypertension 2000; 36(5):839-844
-
(2000)
Hypertension
, vol.36
, Issue.5
, pp. 839-844
-
-
Stevenson, K.M.1
Edgley, A.J.2
Bergstrom, G.3
-
179
-
-
0034072219
-
Angiotensin II blockade and low-protein diet produce additive therapeutic effects in experimental glomerulonephritis
-
Peters H, Border WA, Noble NA. Angiotensin II blockade and low-protein diet produce additive therapeutic effects in experimental glomerulonephritis. Kidney Int 2000; 57(4):1493-1501
-
(2000)
Kidney Int
, vol.57
, Issue.4
, pp. 1493-1501
-
-
Peters, H.1
Border, W.A.2
Noble, N.A.3
-
180
-
-
77953670159
-
Role of Fosinopril and Valsartan on Klotho Gene Expression Induced by Angiotensin II in Rat Renal Tubular Epithelial Cells
-
Zhou Q, Lin S, Tang R et al. Role of Fosinopril and Valsartan on Klotho Gene Expression Induced by Angiotensin II in Rat Renal Tubular Epithelial Cells. Kidney Blood Press Res 2010; 33(3):186-192
-
(2010)
Kidney Blood Press Res
, vol.33
, Issue.3
, pp. 186-192
-
-
Zhou, Q.1
Lin, S.2
Tang, R.3
-
181
-
-
5444269240
-
HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells
-
Narumiya H, Sasaki S, Kuwahara N et al. HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells. Cardiovasc Res 2004; 64(2):331-336
-
(2004)
Cardiovasc Res
, vol.64
, Issue.2
, pp. 331-336
-
-
Narumiya, H.1
Sasaki, S.2
Kuwahara, N.3
-
182
-
-
73349109833
-
Urinary biomarkers for the detection of renal injury
-
Rosner MH. Urinary biomarkers for the detection of renal injury. Adv Clin Chem 2009; 49:73-97
-
(2009)
Adv Clin Chem
, vol.49
, pp. 73-97
-
-
Rosner, M.H.1
-
183
-
-
49549122251
-
Biomarker candidates for cardiovascular disease andbone metabolism disorders in chronic kidney disease: A systems biology perspective
-
PercoP,WilflingsederJ,BernthalerAetal. Biomarker candidates for cardiovascular disease andbone metabolism disorders in chronic kidney disease: a systems biology perspective. J Cell Mol Med 2008; 12(4):1177-1187
-
(2008)
J Cell Mol Med
, vol.12
, Issue.4
, pp. 1177-1187
-
-
Perco, P.1
Wilflingseder, J.2
Bernthaler, A.3
-
184
-
-
67650745578
-
Review article: Biomarkers of clinical outcomes in advanced chronic kidney disease
-
Kovesdy CP, Kalantar-Zadeh K. Review article: Biomarkers of clinical outcomes in advanced chronic kidney disease. Nephrology (Carlton) 2009; 14(4):408-415
-
(2009)
Nephrology (Carlton)
, vol.14
, Issue.4
, pp. 408-415
-
-
Kovesdy, C.P.1
Kalantar-Zadeh, K.2
-
185
-
-
78049437396
-
The use of targeted biomarkers for chronic kidney disease
-
Devarajan P. The use of targeted biomarkers for chronic kidney disease. Adv Chronic Kidney Dis 2010; 17(6):469-479
-
(2010)
Adv Chronic Kidney Dis
, vol.17
, Issue.6
, pp. 469-479
-
-
Devarajan, P.1
-
186
-
-
77952600328
-
Proteinuria versus albuminuria in chronic kidney disease
-
Guh JY. Proteinuria versus albuminuria in chronic kidney disease. Nephrology (Carlton) 2010; 15(Suppl 2):53-56
-
(2010)
Nephrology (Carlton)
, vol.15
, Issue.SUPPL. 2
, pp. 53-56
-
-
Guh, J.Y.1
-
187
-
-
0001615007
-
Reference values for cystatin C serum concentrations in children
-
Bokenkamp A, Domanetzki M, Zinck R et al. Reference values for cystatin C serum concentrations in children. PediatrNephrol 1998; 12(2):125-129
-
(1998)
PediatrNephrol
, vol.12
, Issue.2
, pp. 125-129
-
-
Bokenkamp, A.1
Domanetzki, M.2
Zinck, R.3
-
188
-
-
0034813323
-
Determination of serum cystatin C: Biological variation and reference values
-
Galteau MM, Guyon M, Gueguen R et al. Determination of serum cystatin C: biological variation and reference values. Clin Chem Lab Med 2001; 39(9):850-857
-
(2001)
Clin Chem Lab Med
, vol.39
, Issue.9
, pp. 850-857
-
-
Galteau, M.M.1
Guyon, M.2
Gueguen, R.3
-
189
-
-
33645452545
-
Cystatin C and mortality risk in the elderly: The health, aging, and body composition study
-
Shlipak MG, Wassel Fyr CL, Chertow GM et al. Cystatin C and mortality risk in the elderly: the health, aging, and body composition study. J Am Soc Nephrol 2006; 17(1):254-261
-
(2006)
J Am Soc Nephrol
, vol.17
, Issue.1
, pp. 254-261
-
-
Shlipak, M.G.1
Wassel Fyr, C.L.2
Chertow, G.M.3
-
190
-
-
36849052536
-
Cystatin C and risk of heart failure in the Physicians' Health Study (PHS)
-
Djousse L, Kurth T, Gaziano JM. Cystatin C and risk of heart failure in the Physicians' Health Study (PHS). Am Heart J 2008; 155(1):82-86
-
(2008)
Am Heart J
, vol.155
, Issue.1
, pp. 82-86
-
-
Djousse, L.1
Kurth, T.2
Gaziano, J.M.3
-
191
-
-
68949211783
-
Changes in adiponectin and the risk of sudden death, stroke, myocardial infarction, and mortality in hemodialysis patients
-
Drechsler C, Krane V, Winkler K et al. Changes in adiponectin and the risk of sudden death, stroke, myocardial infarction, and mortality in hemodialysis patients. Kidney Int 2009; 76(5):567-575
-
(2009)
Kidney Int
, vol.76
, Issue.5
, pp. 567-575
-
-
Drechsler, C.1
Krane, V.2
Winkler, K.3
-
192
-
-
47949121132
-
Serum adiponectin and progression of diabetic nephropathy in patients with type 1 diabetes
-
Saraheimo M, Forsblom C, Thorn L et al. Serum adiponectin and progression of diabetic nephropathy in patients with type 1 diabetes. Diabetes Care 2008; 31(6):1165-1169
-
(2008)
Diabetes Care
, vol.31
, Issue.6
, pp. 1165-1169
-
-
Saraheimo, M.1
Forsblom, C.2
Thorn, L.3
-
193
-
-
0021731736
-
Urinary excretion of glycosaminoglycans and brush border and lysosomal enzymes as markers of glomerular and tubular involvement in kidney diseases
-
Baggio B, Gambaro G, Briani G et al. Urinary excretion of glycosaminoglycans and brush border and lysosomal enzymes as markers of glomerular and tubular involvement in kidney diseases. Contrib Nephrol 1984; 42:107-110
-
(1984)
Contrib Nephrol
, vol.42
, pp. 107-110
-
-
Baggio, B.1
Gambaro, G.2
Briani, G.3
-
194
-
-
33846007117
-
Gamma-Glutamyltransferase as a predictor of chronic kidney disease in nonhypertensive and nondiabetic Korean men
-
Ryu S, Chang Y, Kim DI et al. gamma-Glutamyltransferase as a predictor of chronic kidney disease in nonhypertensive and nondiabetic Korean men. Clin Chem 2007; 53(1):71-77
-
(2007)
Clin Chem
, vol.53
, Issue.1
, pp. 71-77
-
-
Ryu, S.1
Chang, Y.2
Kim, D.I.3
-
195
-
-
66449100864
-
Urinary endothelin-1 in chronic kidney disease and as a marker of disease activity in lupus nephritis
-
Dhaun N, Lilitkarntakul P, Macintyre IM et al. Urinary endothelin-1 in chronic kidney disease and as a marker of disease activity in lupus nephritis. Am J Physiol Renal Physiol 2009; 296(6):F1477-F1483
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, Issue.6
-
-
Dhaun, N.1
Lilitkarntakul, P.2
MacIntyre, I.M.3
-
196
-
-
58449124960
-
Endothelin-1 and F2-isoprostane relate to and predict renal dysfunction in hypertensive patients
-
Cottone S, Mule G, Guarneri M et al. Endothelin-1 and F2-isoprostane relate to and predict renal dysfunction in hypertensive patients. Nephrol Dial Transplant 2009; 24(2):497-503
-
(2009)
Nephrol Dial Transplant
, vol.24
, Issue.2
, pp. 497-503
-
-
Cottone, S.1
Mule, G.2
Guarneri, M.3
-
197
-
-
77953358915
-
Hyperuricemia as an independent risk factor of chronic kidney disease in middle-aged and elderly population
-
Chang HY, Tung CW, Lee PH et al. Hyperuricemia as an independent risk factor of chronic kidney disease in middle-aged and elderly population. Am J Med Sci 2010; 339(6):509-515
-
(2010)
Am J Med Sci
, vol.339
, Issue.6
, pp. 509-515
-
-
Chang, H.Y.1
Tung, C.W.2
Lee, P.H.3
-
198
-
-
73349138594
-
Uric acid: A novel mediator and marker of risk in chronic kidney disease?
-
Feig DI. Uric acid: a novel mediator and marker of risk in chronic kidney disease? Curr Opin Nephrol Hypertens 2009; 18(6):526-530
-
(2009)
Curr Opin Nephrol Hypertens
, vol.18
, Issue.6
, pp. 526-530
-
-
Feig, D.I.1
-
199
-
-
64749086523
-
Uric acid and long-term outcomes in CKD
-
Madero M, Sarnak MJ, Wang X et al. Uric acid and long-term outcomes in CKD. Am J Kidney Dis 2009; 53(5):796-803
-
(2009)
Am J Kidney Dis
, vol.53
, Issue.5
, pp. 796-803
-
-
Madero, M.1
Sarnak, M.J.2
Wang, X.3
-
200
-
-
77956884451
-
FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease
-
Yilmaz MI, Sonmez A, Saglam M et al. FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease. Kidney Int 2010; 78(7):679-685
-
(2010)
Kidney Int
, vol.78
, Issue.7
, pp. 679-685
-
-
Yilmaz, M.I.1
Sonmez, A.2
Saglam, M.3
-
202
-
-
0034864995
-
Gene therapy approach in renal disease in the 21st century
-
Imai E. Gene therapy approach in renal disease in the 21st century. Nephrol Dial Transplant2001; 16 Suppl 5:26-34
-
(2001)
Nephrol Dial Transplant
, vol.16
, Issue.SUPPL. 5
, pp. 26-34
-
-
Imai, E.1
-
203
-
-
70349659193
-
Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage
-
Wang Y, Sun Z. Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage. Hypertension 2009; 54(4):810-817
-
(2009)
Hypertension
, vol.54
, Issue.4
, pp. 810-817
-
-
Wang, Y.1
Sun, Z.2
-
204
-
-
33846416897
-
Drug insight: Vitamin D analogs in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease
-
Brown AJ, Slatopolsky E. Drug insight: vitamin D analogs in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Nat Clin Pract Endocrinol Metab 2007; 3(2):134-144
-
(2007)
Nat Clin Pract Endocrinol Metab
, vol.3
, Issue.2
, pp. 134-144
-
-
Brown, A.J.1
Slatopolsky, E.2
-
205
-
-
39749097199
-
Role of vitamin D deficiency in chronic kidney disease
-
Gal-Moscovici A, Sprague SM. Role of vitamin D deficiency in chronic kidney disease. J Bone Miner Res 2007; 22(Suppl 2):V91-V94
-
(2007)
J Bone Miner Res
, vol.22
, Issue.SUPPL. 2
-
-
Gal-Moscovici, A.1
Sprague, S.M.2
-
206
-
-
77954315973
-
Use of vitamin D in chronic kidney disease patients
-
Gal-Moscovici A, Sprague SM. Use of vitamin D in chronic kidney disease patients. Kidney Int 2010; 78(2):146-151
-
(2010)
Kidney Int
, vol.78
, Issue.2
, pp. 146-151
-
-
Gal-Moscovici, A.1
Sprague, S.M.2
-
207
-
-
23844449784
-
Vitamin D treatment in chronic kidney disease
-
Andress DL. Vitamin D treatment in chronic kidney disease. Semin Dial 2005; 18(4):315-321
-
(2005)
Semin Dial
, vol.18
, Issue.4
, pp. 315-321
-
-
Andress, D.L.1
-
208
-
-
52649083791
-
Epoetin alfa and darbepoetin alfa: Effects on ventricular hypertrophy in patients with chronic kidney disease
-
Chen HH, Tarng DC, Lee KF et al. Epoetin alfa and darbepoetin alfa: effects on ventricular hypertrophy in patients with chronic kidney disease. J Nephrol 2008; 21(4):543-549
-
(2008)
J Nephrol
, vol.21
, Issue.4
, pp. 543-549
-
-
Chen, H.H.1
Tarng, D.C.2
Lee, K.F.3
-
209
-
-
0022857775
-
Erythropoiesis in the anaemia of chronic renal failure: The response to CAPD
-
Coles GA, Cavill I. Erythropoiesis in the anaemia of chronic renal failure: the response to CAPD. Nephrol DialTransplant 1986; 1(3):170-174
-
(1986)
Nephrol DialTransplant
, vol.1
, Issue.3
, pp. 170-174
-
-
Coles, G.A.1
Cavill, I.2
-
210
-
-
70350356856
-
Erythropoiesis-stimulating agents in anemia: Use and misuse
-
Dharmarajan TS, Widjaja D. Erythropoiesis-stimulating agents in anemia: use and misuse. J Am Med Dir Assoc 2009; 10(9):607-616
-
(2009)
J Am Med Dir Assoc
, vol.10
, Issue.9
, pp. 607-616
-
-
Dharmarajan, T.S.1
Widjaja, D.2
-
211
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 2006; 281(10):6120-6123
-
(2006)
J Biol Chem
, vol.281
, Issue.10
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
-
212
-
-
0021930431
-
Captopril slows the progression of chronic renal disease in partially nephrectomized rats
-
Hall RL, Wilke WL, Fettman MJ. Captopril slows the progression of chronic renal disease in partially nephrectomized rats. Toxicol Appl Pharmacol 1985; 80(3):517-526
-
(1985)
Toxicol Appl Pharmacol
, vol.80
, Issue.3
, pp. 517-526
-
-
Hall, R.L.1
Wilke, W.L.2
Fettman, M.J.3
-
213
-
-
0025215318
-
Angiotensin II augments medullary hypoxia and predisposes to acute renal failure
-
Brezis M, Greenfeld Z, Shina A et al. Angiotensin II augments medullary hypoxia and predisposes to acute renal failure. Eur J Clin Invest 1990; 20(2):199-207
-
(1990)
Eur J Clin Invest
, vol.20
, Issue.2
, pp. 199-207
-
-
Brezis, M.1
Greenfeld, Z.2
Shina, A.3
-
214
-
-
0026161378
-
The renin-angiotensin system: Renal actions and blood pressure regulation
-
Hall JE. The renin-angiotensin system: renal actions and blood pressure regulation. Compr Ther 1991; 17(5):8-17
-
(1991)
Compr Ther
, vol.17
, Issue.5
, pp. 8-17
-
-
Hall, J.E.1
-
215
-
-
0031973279
-
The renoprotective effect of angiotensin-converting enzyme inhibitors in experimental chronic renal failure is not dependent on enhanced kinin activity
-
Nabokov A, Amann K, Gassmann P et al. The renoprotective effect of angiotensin-converting enzyme inhibitors in experimental chronic renal failure is not dependent on enhanced kinin activity. Nephrol Dial Transplant 1998; 13(1):173-176
-
(1998)
Nephrol Dial Transplant
, vol.13
, Issue.1
, pp. 173-176
-
-
Nabokov, A.1
Amann, K.2
Gassmann, P.3
-
216
-
-
0036899292
-
Angiotensin II and oxidative stress in Dahl Salt-sensitive rat with heart failure
-
Tojo A, Onozato ML, Kobayashi N et al. Angiotensin II and oxidative stress in Dahl Salt-sensitive rat with heart failure. Hypertension 2002; 40(6):834-839
-
(2002)
Hypertension
, vol.40
, Issue.6
, pp. 834-839
-
-
Tojo, A.1
Onozato, M.L.2
Kobayashi, N.3
-
217
-
-
0036899332
-
Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage
-
Muller DN, Mullally A, Dechend R et al. Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage. Hypertension 2002; 40(6):840-846
-
(2002)
Hypertension
, vol.40
, Issue.6
, pp. 840-846
-
-
Muller, D.N.1
Mullally, A.2
Dechend, R.3
-
218
-
-
0037377192
-
Proinflammatory effects of oxidative stress in chronic kidney disease: Role of additional angiotensin II blockade
-
Agarwal R. Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade. Am J Physiol Renal Physiol 2003; 284(4):F863-F869
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, Issue.4
-
-
Agarwal, R.1
-
219
-
-
33748316445
-
The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease
-
Remuzzi G, Perico N, Macia M et al. The role of renin-angiotensin- aldosterone system in the progression of chronic kidney disease. Kidney Int 2005; 99(Suppl):S57-S65
-
(2005)
Kidney Int
, vol.99
, Issue.SUPPL.
-
-
Remuzzi, G.1
Perico, N.2
MacIa, M.3
-
220
-
-
26944503427
-
Renal protection in hypertensive patients: Selection of antihypertensive therapy
-
Wenzel RR. Renal protection in hypertensive patients: selection of antihypertensive therapy. Drugs 2005; 65 Suppl 2:29-39
-
(2005)
Drugs
, vol.65
, Issue.SUPPL. 2
, pp. 29-39
-
-
Wenzel, R.R.1
-
221
-
-
33750605324
-
The effect of angiotensin II receptor blockade on an end-stage renal failure model of type 2 diabetes
-
Mizuno M, Sada T, Kato M et al. The effect of angiotensin II receptor blockade on an end-stage renal failure model of type 2 diabetes. J Cardiovasc Pharmacol 2006; 48(4):135-142
-
(2006)
J Cardiovasc Pharmacol
, vol.48
, Issue.4
, pp. 135-142
-
-
Mizuno, M.1
Sada, T.2
Kato, M.3
-
222
-
-
33845348921
-
Antihypertensive and renal protective effects of renin-angiotens in system blockade in uremic rats treated with erythropoietin
-
Lebel M, Rodrigue ME, Agharazii M et al. Antihypertensive and renal protective effects of renin-angiotens in system blockade in uremic rats treated with erythropoietin. Am J Hypertens 2006; 19(12):1286-1292
-
(2006)
Am J Hypertens
, vol.19
, Issue.12
, pp. 1286-1292
-
-
Lebel, M.1
Rodrigue, M.E.2
Agharazii, M.3
-
223
-
-
30644459712
-
The klotho gene: A gene predominantly expressed in the kidney is a fundamental regulator of aging and calcium/phosphorus metabolism
-
Negri AL. The klotho gene: a gene predominantly expressed in the kidney is a fundamental regulator of aging and calcium/phosphorus metabolism. J Nephrol 2005; 18(6):654-658
-
(2005)
J Nephrol
, vol.18
, Issue.6
, pp. 654-658
-
-
Negri, A.L.1
-
224
-
-
37049021538
-
HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis
-
Kuwahara N, Sasaki S, Kobara M et al. HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis. Int J Cardiol 2008; 123(2):84-90
-
(2008)
Int J Cardiol
, vol.123
, Issue.2
, pp. 84-90
-
-
Kuwahara, N.1
Sasaki, S.2
Kobara, M.3
-
225
-
-
77956251466
-
Pharmacogenomic, physiological, and biochemical investigations on safety and efficacy biomarkers associated with the peroxisome proliferator-activated receptor-gamma activator rosiglitazone in rodents: A translational medicine investigation
-
Wang X, LiuX, Zhan Y et al. Pharmacogenomic, physiological, and biochemical investigations on safety and efficacy biomarkers associated with the peroxisome proliferator-activated receptor-gamma activator rosiglitazone in rodents: a translational medicine investigation. J Pharmacol Exp Ther 2010; 334(3):820-829
-
(2010)
J Pharmacol Exp Ther
, vol.334
, Issue.3
, pp. 820-829
-
-
Wang, X.1
Liux Zhan, Y.2
-
226
-
-
50849091263
-
Klotho is a target gene ofPPAR-gamma
-
Zhang H, Li Y,FanY et al. Klotho is a target gene ofPPAR-gamma. Kidney Int 2008; 74(6):732-739
-
(2008)
Kidney Int
, vol.74
, Issue.6
, pp. 732-739
-
-
Zhang, H.1
Li, Y.2
Fan, Y.3
-
227
-
-
50849105720
-
PPAR-gamma and aging: One link through klotho?
-
Zhang R, Zheng F. PPAR-gamma and aging: one link through klotho? Kidney Int 2008; 74(6):702-704
-
(2008)
Kidney Int
, vol.74
, Issue.6
, pp. 702-704
-
-
Zhang, R.1
Zheng, F.2
-
228
-
-
70350633113
-
Potential utility of PPARalpha activation in the prevention of ischemic and drug-induced acute renal damage
-
Lopez-Hernandez FJ, Lopez-Novoa JM. Potential utility of PPARalpha activation in the prevention of ischemic and drug-induced acute renal damage. Kidney Int 2009; 76(10):1022-1024
-
(2009)
Kidney Int
, vol.76
, Issue.10
, pp. 1022-1024
-
-
Lopez-Hernandez, F.J.1
Lopez-Novoa, J.M.2
-
229
-
-
70350700478
-
Transgenic expression of proximal tubule peroxisome proliferator- activated receptor-alpha in mice confers protection during acute kidney injury
-
Li S, Nagothu KK, Desai V et al. Transgenic expression of proximal tubule peroxisome proliferator-activated receptor-alpha in mice confers protection during acute kidney injury. Kidney Int 2009; 76(10):1049-1062
-
(2009)
Kidney Int
, vol.76
, Issue.10
, pp. 1049-1062
-
-
Li, S.1
Nagothu, K.K.2
Desai, V.3
-
230
-
-
35248845665
-
Anti-oxidative effect of Klotho on endothelial cells through cAMP activation
-
Rakugi H, Matsukawa N, Ishikawa K et al. Anti-oxidative effect of Klotho on endothelial cells through cAMP activation. Endocrine 2007; 31(1):82-87
-
(2007)
Endocrine
, vol.31
, Issue.1
, pp. 82-87
-
-
Rakugi, H.1
Matsukawa, N.2
Ishikawa, K.3
-
232
-
-
72949102617
-
Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70
-
Sugiura H, Yoshida T, Mitobe M et al. Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70. Nephrol Dial Transplant 2010; 25(1):60-68
-
(2010)
Nephrol Dial Transplant
, vol.25
, Issue.1
, pp. 60-68
-
-
Sugiura, H.1
Yoshida, T.2
Mitobe, M.3
|