Gelsolin expression increases β1-integrin affinity and L1210 cell adhesion

Cytoskeleton

Volumn 70, Issue 7, 2013, Pages 385-393

  Langereis, Jeroen D ^a,c   Koenderman, Leo ^a   Huttenlocher, Anna ^b   Ulfman, Laurien H ^a,d  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d FRIESLANDCAMPINA   (Netherlands)

Author keywords

Attachment; Cell membrane; Cytoskeleton; Gelsolin; Migration

Indexed keywords

BETA1 INTEGRIN; COLLAGEN; GELSOLIN; JASPAMIDE; LATRUNCULIN B;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEPOLARIZATION; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ATTACHMENT; CELL MEMBRANE; CYTOSKELETON; GELSOLIN; MIGRATION;

ACTINS; ANIMALS; ANTIGENS, CD29; CELL ADHESION; CELL MEMBRANE; GELSOLIN; GENE KNOCKDOWN TECHNIQUES; HUMANS; LEUKEMIA L1210; MICE; SIGNAL TRANSDUCTION;

EID: 84880699172     PISSN: 19493584     EISSN: 19493592     Source Type: Journal    
DOI: 10.1002/cm.21112     Document Type: Article

References (35)

1. Arora PD, Glogauer M, Kapus A, Kwiatkowski DJ, McCulloch CA. 2004. Gelsolin mediates collagen phagocytosis through a rac-dependent step. Mol Biol Cell 15(2):588-599.
2. Arora PD, Chan MW, Anderson RA, Janmey PA, McCulloch CA. 2005. Separate functions of gelsolin mediate sequential steps of collagen phagocytosis. Mol Biol Cell 16(11):5175-5190.
3. Bennett JS, Zigmond S, Vilaire G, Cunningham ME, Bednar B. 1999. The platelet cytoskeleton regulates the affinity of the integrin alpha(IIb)beta(3) for fibrinogen. J Biol Chem 274(36):25301-25307.
4. Brandsma D, Ulfman L, Reijneveld JC, Bracke M, Taphoorn MJ, Zwaginga JJ, Gebbink MF, de Boer H, Koenderman L, Voest EE. 2006. Constitutive integrin activation on tumor cells contributes to progression of leptomeningeal metastases. Neuro Oncol 8(2):127-136.
5. Burtnick LD, Koepf EK, Grimes J, Jones EY, Stuart DI, McLaughlin PJ, Robinson RC. 1997. The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation. Cell 90(4):661-670.
6. Carman CV, Springer TA. 2003. Integrin avidity regulation: are changes in affinity and conformation underemphasized? Curr Opin Cell Biol 15(5):547-556.
7. Chellaiah M, Kizer N, Silva M, Alvarez U, Kwiatkowski D, Hruska KA. 2000. Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength. J Cell Biol 148(4):665-678.
8. Constantin G, Majeed M, Giagulli C, Piccio L, Kim JY, Butcher EC, Laudanna C. 2000. Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. Immunity 13(6):759-769.
9. Critchley DR. 2004. Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion. Biochem Soc Trans 32(Pt 5):831-836.
10. Cunningham CC, Stossel TP, Kwiatkowski DJ. 1991. Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin. Science 251(4998):1233-1236.
11. Driessens MH, Van Rijthoven EA, Kemperman H, Roos E. 1995. Adhesion of lymphoma cells to fibronectin: differential use of alpha 4 beta 1 and alpha 5 beta 1 integrins and stimulation by the 9EG7 mAb against the murine beta 1 integrin subunit. Cell Adhes Commun 3(4):327-336.
12. Harburger DS, Bouaouina M, Calderwood DA. 2009. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem 284(17):11485-11497.
13. Hartwig JH. 1992. Mechanisms of actin rearrangements mediating platelet activation. J Cell Biol 118(6):1421-1442.
14. Howard T, Chaponnier C, Yin H, Stossel T. 1990. Gelsolin-actin interaction and actin polymerization in human neutrophils. J Cell Biol 110(6):1983-1991.
15. Hyduk SJ, Rullo J, Cano AP, Xiao H, Chen M, Moser M, Cybulsky MI. 2011. Talin-1 and kindlin-3 regulate alpha4beta1 integrin-mediated adhesion stabilization, but not G protein-coupled receptor-induced affinity upregulation. J Immunol 187(8):4360-4368.
16. Hynes RO. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69(1):11-25.
17. Jones SL, Wang J, Turck CW, Brown EJ. 1998. A role for the actin-bundling protein L-plastin in the regulation of leukocyte integrin function. Proc Natl Acad Sci USA 95(16):9331-9336.
18. Kinashi T. 2005. Intracellular signalling controlling integrin activation in lymphocytes. Nat Rev Immunol 5(7):546-559.
19. Kinashi T. 2007. Integrin regulation of lymphocyte trafficking: lessons from structural and signaling studies. Adv Immunol 93:185-227.
20. Kwiatkowski DJ, Mehl R, Izumo S, Nadal-Ginard B, Yin HL. 1988a. Muscle is the major source of plasma gelsolin. J Biol Chem 263(17):8239-8243.
21. Kwiatkowski DJ, Mehl R, Yin HL. 1988b. Genomic organization and biosynthesis of secreted and cytoplasmic forms of gelsolin. J Cell Biol 106(2):375-384.
22. Langereis JD, Prinsen BH, de Sain-van der Velden MG, Coppens CJ, Koenderman L, Ulfman LH. 2009. A 2D-DIGE approach to identify proteins involved in inside-out control of integrins. J Proteome Res 8(8):3824-3833.
23. Laudanna C, Kim JY, Constantin G, Butcher E. 2002. Rapid leukocyte integrin activation by chemokines. Immunol Rev 186:37-46.
24. Lenter M, Uhlig H, Hamann A, Jeno P, Imhof B, Vestweber D. 1993. A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1. Proc Natl Acad Sci USA 90(19):9051-9055.
25. Ley K, Laudanna C, Cybulsky MI, Nourshargh S. 2007. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 7(9):678-689.
26. Liu S, Thomas SM, Woodside DG, Rose DM, Kiosses WB, Pfaff M, Ginsberg MH. 1999. Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses. Nature 402(6762):676-681.
27. Moser M, Nieswandt B, Ussar S, Pozgajova M, Fassler R. 2008. Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med 14(3):325-330.
28. Oudijk EJ, Nijhuis EH, Zwank MD, van de Graaf EA, Mager HJ, Coffer PJ, Lammers JW, Koenderman L. 2005. Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils. Thorax 60(7):538-544.
29. Stewart MP, McDowall A, Hogg N. 1998. LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain. J Cell Biol 140(3):699-707.
30. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. 2003. Talin binding to integrin beta tails: a final common step in integrin activation. Science 302(5642):103-106.
31. Tellam R, Frieden C. 1982. Cytochalasin D and platelet gelsolin accelerate actin polymer formation. A model for regulation of the extent of actin polymer formation in vivo. Biochemistry 21(13):3207-3014.
32. Yin HL, Stossel TP. 1979. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 281(5732):583-586.
33. Yin HL, Albrecht JH, Fattoum A. 1981. Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues. J Cell Biol 91(3 Pt 1):901-906.
34. Zaidel-Bar R, Itzkovitz S, Ma'ayan A, Iyengar R, Geiger B. 2007. Functional atlas of the integrin adhesome. Nat Cell Biol 9(8):858-867.
35. Ziegler WH, Gingras AR, Critchley DR, Emsley J. 2008. Integrin connections to the cytoskeleton through talin and vinculin. Biochem Soc Trans 36(Pt 2):235-239.