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Volumn 33, Issue 14, 2013, Pages 2732-2747

Impaired resection of meiotic double-strand breaks channels repair to nonhomologous end joining in caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; GERM CELL; HOMOLOGOUS RECOMBINATION; IMMUNOHISTOCHEMISTRY; MEIOTIC PROPHASE I; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROPHASE; WESTERN BLOTTING;

EID: 84880694110     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00055-13     Document Type: Article
Times cited : (52)

References (62)
  • 1
    • 0030893115 scopus 로고    scopus 로고
    • Meiosis-specific DNA doublestrand breaks are catalyzed by Spo11, a member of a widely conserved protein family
    • Cell
    • Keeney S, Giroux CN, Kleckner N. 1997. Meiosis-specific DNA doublestrand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell 88:375-384.
    • (1997) , vol.88 , pp. 375-384
    • Keeney, S.1    Giroux, C.N.2    Kleckner, N.3
  • 2
    • 23944459784 scopus 로고    scopus 로고
    • Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
    • Nature
    • Neale MJ, Pan J, Keeney S. 2005. Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature 436:1053-1057.
    • (2005) , vol.436 , pp. 1053-1057
    • Neale, M.J.1    Pan, J.2    Keeney, S.3
  • 3
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Nature
    • Mimitou EP, Symington LS. 2008. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455:770-774.
    • (2008) , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 4
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • Cell
    • Zhu Z, Chung WH, Shim EY, Lee SE, Ira G. 2008. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134:981-994.
    • (2008) , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5
  • 5
    • 0032527973 scopus 로고    scopus 로고
    • Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
    • Gasior SL, Wong AK, Kora Y, Shinohara A, Bishop DK. 1998. Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev. 12:2208-2221.
    • (1998) Genes Dev. , vol.12 , pp. 2208-2221
    • Gasior, S.L.1    Wong, A.K.2    Kora, Y.3    Shinohara, A.4    Bishop, D.K.5
  • 6
    • 0026751113 scopus 로고
    • Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
    • Cell
    • Shinohara A, Ogawa H, Ogawa T. 1992. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69:457-470.
    • (1992) , vol.69 , pp. 457-470
    • Shinohara, A.1    Ogawa, H.2    Ogawa, T.3
  • 7
    • 0027978039 scopus 로고
    • Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein
    • Science
    • Sung P. 1994. Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science 265:1241-1243.
    • (1994) , vol.265 , pp. 1241-1243
    • Sung, P.1
  • 8
    • 0028972024 scopus 로고
    • Identification of double Holliday junctions as intermediates in meiotic recombination
    • Cell
    • Schwacha A, Kleckner N. 1995. Identification of double Holliday junctions as intermediates in meiotic recombination. Cell 83:783-791.
    • (1995) , vol.83 , pp. 783-791
    • Schwacha, A.1    Kleckner, N.2
  • 9
    • 0028914077 scopus 로고
    • Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae
    • Genetics
    • Johzuka K, Ogawa H. 1995. Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics 139:1521-1532.
    • (1995) , vol.139 , pp. 1521-1532
    • Johzuka, K.1    Ogawa, H.2
  • 10
    • 0031983191 scopus 로고    scopus 로고
    • A novel mre11 mutation impairs processing of double-strand breaks ofDNAduring both mitosis and meiosis
    • Tsubouchi H, Ogawa H. 1998. A novel mre11 mutation impairs processing of double-strand breaks ofDNAduring both mitosis and meiosis. Mol. Cell. Biol. 18:260-268.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 260-268
    • Tsubouchi, H.1    Ogawa, H.2
  • 11
    • 3142704347 scopus 로고    scopus 로고
    • Conserved and nonconserved proteins for meioticDNAbreakage and repair in yeasts
    • Genetics
    • Young JA, Hyppa RW, Smith GR. 2004. Conserved and nonconserved proteins for meioticDNAbreakage and repair in yeasts. Genetics 167:593-605.
    • (2004) , vol.167 , pp. 593-605
    • Young, J.A.1    Hyppa, R.W.2    Smith, G.R.3
  • 12
    • 58149308077 scopus 로고    scopus 로고
    • Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRNdependent meiotic functions
    • Hartsuiker E, Mizuno K, Molnar M, Kohli J, Ohta K, Carr AM. 2009. Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRNdependent meiotic functions. Mol. Cell. Biol. 29:1671-1681.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1671-1681
    • Hartsuiker, E.1    Mizuno, K.2    Molnar, M.3    Kohli, J.4    Ohta, K.5    Carr, A.M.6
  • 13
    • 4043131735 scopus 로고    scopus 로고
    • Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis
    • Puizina J, Siroky J, Mokros P, Schweizer D, Riha K. 2004. Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis. Plant Cell 16:1968-1978.
    • (2004) Plant Cell , vol.16 , pp. 1968-1978
    • Puizina, J.1    Siroky, J.2    Mokros, P.3    Schweizer, D.4    Riha, K.5
  • 14
    • 0032476658 scopus 로고    scopus 로고
    • Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
    • Furuse M, Nagase Y, Tsubouchi H, Murakami-Murofushi K, Shibata T, Ohta K. 1998. Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J. 17:6412-6425.
    • (1998) EMBO J. , vol.17 , pp. 6412-6425
    • Furuse, M.1    Nagase, Y.2    Tsubouchi, H.3    Murakami-Murofushi, K.4    Shibata, T.5    Ohta, K.6
  • 15
    • 0032567108 scopus 로고    scopus 로고
    • Complex formation and functional versatility of Mre11 of budding yeast in recombination
    • Cell
    • Usui T, Ohta T, Oshiumi H, Tomizawa J, Ogawa H, Ogawa T. 1998.Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell 95:705-716.
    • (1998) , vol.95 , pp. 705-716
    • Usui, T.1    Ohta, T.2    Oshiumi, H.3    Tomizawa, J.4    Ogawa, H.5    Ogawa, T.6
  • 16
    • 0032931844 scopus 로고    scopus 로고
    • The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
    • Moreau S, Ferguson JR, Symington LS. 1999. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19:556-566.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 556-566
    • Moreau, S.1    Ferguson, J.R.2    Symington, L.S.3
  • 17
    • 73649143128 scopus 로고    scopus 로고
    • Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single class of oligonucleotides in fission yeast
    • doi:10.1371/journal.pgen.1000722.
    • Rothenberg M, Kohli J, Ludin K. 2009. Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single class of oligonucleotides in fission yeast. PLoS Genet. 5:e1000722. doi:10.1371/journal.pgen.1000722.
    • (2009) PLoS Genet. , vol.5
    • Rothenberg, M.1    Kohli, J.2    Ludin, K.3
  • 18
    • 71949092988 scopus 로고    scopus 로고
    • Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes
    • Milman N, Higuchi E, Smith GR. 2009. Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes. Mol. Cell. Biol. 29:5998-6005.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5998-6005
    • Milman, N.1    Higuchi, E.2    Smith, G.R.3
  • 19
    • 80855144827 scopus 로고    scopus 로고
    • Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
    • Garcia V, Phelps SE, Gray S, Neale MJ. 2011. Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1. Nature 479:241-244.
    • (2011) Nature , vol.479 , pp. 241-244
    • Garcia, V.1    Phelps, S.E.2    Gray, S.3    Neale, M.J.4
  • 20
    • 0033594904 scopus 로고    scopus 로고
    • Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
    • Luo G, Yao MS, Bender CF, Mills M, Bladl AR, Bradley A, Petrini JH. 1999. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc. Natl. Acad. Sci. U. S. A. 96:7376-7381.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 7376-7381
    • Luo, G.1    Yao, M.S.2    Bender, C.F.3    Mills, M.4    Bladl, A.R.5    Bradley, A.6    Petrini, J.H.7
  • 21
    • 0035936554 scopus 로고    scopus 로고
    • Targeted isruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice
    • Zhu J, Petersen S, Tessarollo L, Nussenzweig A. 2001. Targeted isruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice. Curr. Biol. 11:105-109.
    • (2001) Curr. Biol. , vol.11 , pp. 105-109
    • Zhu, J.1    Petersen, S.2    Tessarollo, L.3    Nussenzweig, A.4
  • 23
    • 2342531078 scopus 로고    scopus 로고
    • Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae
    • Gorski MM, Romeijn RJ, Eeken JC, de Jong AW, van Veen BL, Szuhai K, Mullenders LH, Ferro W, Pastink A. 2004. Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae. DNA Repair 3:603-615.
    • (2004) DNA Repair , vol.3 , pp. 603-615
    • Gorski, M.M.1    Romeijn, R.J.2    Eeken, J.C.3    de Jong, A.W.4    van Veen, B.L.5    Szuhai, K.6    Mullenders, L.H.7    Ferro, W.8    Pastink, A.9
  • 24
    • 52949109260 scopus 로고    scopus 로고
    • Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
    • Cell
    • Buis J, Wu Y, Deng Y, Leddon J, Westfield G, EckersdorffM, Sekiguchi JM, Chang S, Ferguson DO. 2008. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 135:85-96.
    • (2008) , vol.135 , pp. 85-96
    • Buis, J.1    Wu, Y.2    Deng, Y.3    Leddon, J.4    Westfield, G.5    Eckersdorff, M.6    Sekiguchi, J.M.7    Chang, S.8    Ferguson, D.O.9
  • 25
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • Lieber MR. 2010. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 79:181-211.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 26
    • 0037543988 scopus 로고    scopus 로고
    • Non-homologous end joining as an important mutagenic process in cell cycle-arrested cells
    • Heidenreich E, Novotny R, Kneidinger B, Holzmann V, Wintersberger U. 2003. Non-homologous end joining as an important mutagenic process in cell cycle-arrested cells. EMBO J. 22:2274-2283.
    • (2003) EMBO J. , vol.22 , pp. 2274-2283
    • Heidenreich, E.1    Novotny, R.2    Kneidinger, B.3    Holzmann, V.4    Wintersberger, U.5
  • 27
    • 0035872477 scopus 로고    scopus 로고
    • Radiation-induced genomic rearrangements formed by nonhomologous end-joining ofDNAdouble-strand breaks
    • Rothkamm K, Kuhne M, Jeggo PA, Lobrich M. 2001. Radiation-induced genomic rearrangements formed by nonhomologous end-joining ofDNAdouble-strand breaks. Cancer Res. 61:3886-3893.
    • (2001) Cancer Res. , vol.61 , pp. 3886-3893
    • Rothkamm, K.1    Kuhne, M.2    Jeggo, P.A.3    Lobrich, M.4
  • 28
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore JK, Haber JE. 1996. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 29
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • Symington LS, Gautier J. 2011. Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 45:247-271.
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 30
    • 0028246091 scopus 로고
    • Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae
    • Schiestl RH, Zhu J, Petes TD. 1994. Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:4493-4500.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4493-4500
    • Schiestl, R.H.1    Zhu, J.2    Petes, T.D.3
  • 31
    • 0035862948 scopus 로고    scopus 로고
    • Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe
    • Manolis KG, Nimmo ER, Hartsuiker E, Carr AM, Jeggo PA, Allshire RC. 2001. Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe. EMBO J. 20:210-221.
    • (2001) EMBO J. , vol.20 , pp. 210-221
    • Manolis, K.G.1    Nimmo, E.R.2    Hartsuiker, E.3    Carr, A.M.4    Jeggo, P.A.5    Allshire, R.C.6
  • 32
    • 28544436537 scopus 로고    scopus 로고
    • Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
    • Di Virgilio M, Gautier J. 2005. Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11. J. Cell Biol. 171:765-771.
    • (2005) J. Cell Biol. , vol.171 , pp. 765-771
    • Di Virgilio, M.1    Gautier, J.2
  • 33
    • 33746420647 scopus 로고    scopus 로고
    • Developmental modulation of nonhomologous end joining in Caenorhabditis elegans
    • Clejan I, Boerckel J, Ahmed S. 2006. Developmental modulation of nonhomologous end joining in Caenorhabditis elegans. Genetics 173:1301-1317.
    • (2006) Genetics , vol.173 , pp. 1301-1317
    • Clejan, I.1    Boerckel, J.2    Ahmed, S.3
  • 34
    • 16244407723 scopus 로고    scopus 로고
    • RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair
    • Martin JS, Winkelmann N, Petalcorin MI, McIlwraith MJ, Boulton SJ. 2005. RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Mol. Cell. Biol. 25:3127-3139.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3127-3139
    • Martin, J.S.1    Winkelmann, N.2    Petalcorin, M.I.3    McIlwraith, M.J.4    Boulton, S.J.5
  • 35
    • 34548423675 scopus 로고    scopus 로고
    • Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis
    • Smolikov S, Eizinger A, Hurlburt A, Rogers E, Villeneuve AM, Colaiacovo MP. 2007. Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis. Genetics 176:2027-2033.
    • (2007) Genetics , vol.176 , pp. 2027-2033
    • Smolikov, S.1    Eizinger, A.2    Hurlburt, A.3    Rogers, E.4    Villeneuve, A.M.5    Colaiacovo, M.P.6
  • 36
    • 0035282154 scopus 로고    scopus 로고
    • C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint
    • Chin GM, Villeneuve AM. 2001. C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint. Genes Dev. 15:522-534.
    • (2001) Genes Dev. , vol.15 , pp. 522-534
    • Chin, G.M.1    Villeneuve, A.M.2
  • 37
    • 37349101951 scopus 로고    scopus 로고
    • C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression
    • doi:10.1371/journal.pgen.0030191.
    • Hayashi M, Chin GM, Villeneuve AM. 2007. C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression. PLoS Genet. 3:e191. doi:10.1371/journal.pgen.0030191.
    • (2007) PLoS Genet. , vol.3
    • Hayashi, M.1    Chin, G.M.2    Villeneuve, A.M.3
  • 38
    • 0032493878 scopus 로고    scopus 로고
    • Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis
    • Cell
    • Dernburg AF, McDonald K, Moulder G, Barstead R, Dresser M, Villeneuve AM. 1998. Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis. Cell 94:387-398.
    • (1998) , vol.94 , pp. 387-398
    • Dernburg, A.F.1    McDonald, K.2    Moulder, G.3    Barstead, R.4    Dresser, M.5    Villeneuve, A.M.6
  • 39
    • 0036185784 scopus 로고    scopus 로고
    • Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development
    • Rinaldo C, Bazzicalupo P, Ederle S, Hilliard M, La Volpe A. 2002. Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development. Genetics 160:471-479.
    • (2002) Genetics , vol.160 , pp. 471-479
    • Rinaldo, C.1    Bazzicalupo, P.2    Ederle, S.3    Hilliard, M.4    La Volpe, A.5
  • 40
    • 37149043618 scopus 로고    scopus 로고
    • A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination
    • Penkner A, Portik-Dobos Z, Tang L, Schnabel R, Novatchkova M, Jantsch V, Loidl J. 2007. A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J. 26:5071-5082.
    • (2007) EMBO J. , vol.26 , pp. 5071-5082
    • Penkner, A.1    Portik-Dobos, Z.2    Tang, L.3    Schnabel, R.4    Novatchkova, M.5    Jantsch, V.6    Loidl, J.7
  • 41
    • 33645119826 scopus 로고    scopus 로고
    • Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity
    • Krogh BO, Llorente B, Lam A, Symington LS. 2005. Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity. Genetics 171:1561-1570.
    • (2005) Genetics , vol.171 , pp. 1561-1570
    • Krogh, B.O.1    Llorente, B.2    Lam, A.3    Symington, L.S.4
  • 42
    • 0041695475 scopus 로고    scopus 로고
    • Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination
    • Colaiacovo MP, MacQueen AJ, Martinez-Perez E, McDonald K, Adamo A, La Volpe A, Villeneuve AM. 2003. Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination. Dev. Cell 5:463-474.
    • (2003) Dev. Cell , vol.5 , pp. 463-474
    • Colaiacovo, M.P.1    MacQueen, A.J.2    Martinez-Perez, E.3    McDonald, K.4    Adamo, A.5    La Volpe, A.6    Villeneuve, A.M.7
  • 43
    • 0037106122 scopus 로고    scopus 로고
    • Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C
    • MacQueen AJ, Colaiacovo MP, McDonald K, Villeneuve AM. 2002. Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans. Genes Dev. 16:2428-2442.
    • (2002) elegans. Genes Dev. , vol.16 , pp. 2428-2442
    • MacQueen, A.J.1    Colaiacovo, M.P.2    McDonald, K.3    Villeneuve, A.M.4
  • 44
    • 38849207883 scopus 로고    scopus 로고
    • HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis
    • Goodyer W, Kaitna S, Couteau F, Ward JD, Boulton SJ, Zetka M. 2008. HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev. Cell 14:263-274.
    • (2008) Dev. Cell , vol.14 , pp. 263-274
    • Goodyer, W.1    Kaitna, S.2    Couteau, F.3    Ward, J.D.4    Boulton, S.J.5    Zetka, M.6
  • 45
    • 0029145505 scopus 로고
    • MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair
    • Hollingsworth NM, Ponte L, Halsey C. 1995. MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair. Genes Dev. 9:1728-1739.
    • (1995) Genes Dev. , vol.9 , pp. 1728-1739
    • Hollingsworth, N.M.1    Ponte, L.2    Halsey, C.3
  • 46
    • 0033782709 scopus 로고    scopus 로고
    • Caenorhabditis elegans msh-5 is required for both normal and radiationinduced meiotic crossing over but not for completion of meiosis
    • Kelly KO, Dernburg AF, Stanfield GM, Villeneuve AM. 2000. Caenorhabditis elegans msh-5 is required for both normal and radiationinduced meiotic crossing over but not for completion of meiosis. Genetics 156:617-630.
    • (2000) Genetics , vol.156 , pp. 617-630
    • Kelly, K.O.1    Dernburg, A.F.2    Stanfield, G.M.3    Villeneuve, A.M.4
  • 47
    • 0029098961 scopus 로고
    • Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans
    • Barnes TM, Kohara Y, Coulson A, Hekimi S. 1995. Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. Genetics 141:159-179.
    • (1995) Genetics , vol.141 , pp. 159-179
    • Barnes, T.M.1    Kohara, Y.2    Coulson, A.3    Hekimi, S.4
  • 48
    • 38349049460 scopus 로고    scopus 로고
    • Meiotic crossover number and distribution are regulated by a dosage compensation protein that resembles a condensin subunit
    • Tsai CJ, Mets DG, Albrecht MR, Nix P, Chan A, Meyer BJ. 2008. Meiotic crossover number and distribution are regulated by a dosage compensation protein that resembles a condensin subunit. Genes Dev.22:194-211.
    • (2008) Genes Dev. , vol.22 , pp. 194-211
    • Tsai, C.J.1    Mets, D.G.2    Albrecht, M.R.3    Nix, P.4    Chan, A.5    Meyer, B.J.6
  • 49
    • 84859194065 scopus 로고    scopus 로고
    • COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers
    • Cell
    • Yokoo R, Zawadzki KA, Nabeshima K, Drake M, Arur S, Villeneuve AM. 2012. COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers. Cell 149:75-87.
    • (2012) , vol.149 , pp. 75-87
    • Yokoo, R.1    Zawadzki, K.A.2    Nabeshima, K.3    Drake, M.4    Arur, S.5    Villeneuve, A.M.6
  • 50
    • 0033679966 scopus 로고    scopus 로고
    • A conserved check point pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans
    • Gartner A, Milstein S, Ahmed S, Hodgkin J, Hengartner MO. 2000. A conserved checkpoint pathway mediatesDNAdamage-induced apoptosis and cell cycle arrest in C. elegans. Mol. Cell 5:435-443.
    • (2000) Mol. Cell , vol.5 , pp. 435-443
    • Gartner, A.1    Milstein, S.2    Ahmed, S.3    Hodgkin, J.4    Hengartner, M.O.5
  • 51
    • 2442683003 scopus 로고    scopus 로고
    • Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line
    • Wicky C, Alpi A, Passannante M, Rose A, Gartner A, Muller F. 2004. Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line. Mol. Cell. Biol. 24:5016-5027.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5016-5027
    • Wicky, C.1    Alpi, A.2    Passannante, M.3    Rose, A.4    Gartner, A.5    Muller, F.6
  • 52
    • 80053447704 scopus 로고    scopus 로고
    • Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks
    • doi:10.1371/journal.pgen.1002271.
    • Langerak P, Mejia-Ramirez E, Limbo O, Russell P. 2011. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet. 7:e1002271. doi:10.1371/journal.pgen.1002271.
    • (2011) PLoS Genet. , vol.7
    • Langerak, P.1    Mejia-Ramirez, E.2    Limbo, O.3    Russell, P.4
  • 53
    • 77957805302 scopus 로고    scopus 로고
    • Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
    • Mimitou EP, Symington LS. 2010. Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2. EMBO J. 29:3358-3369.
    • (2010) EMBO J. , vol.29 , pp. 3358-3369
    • Mimitou, E.P.1    Symington, L.S.2
  • 54
    • 45149104841 scopus 로고    scopus 로고
    • Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae
    • Wu D, Topper LM, Wilson TE. 2008. Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae. Genetics 178:1237-1249.
    • (2008) Genetics , vol.178 , pp. 1237-1249
    • Wu, D.1    Topper, L.M.2    Wilson, T.E.3
  • 55
    • 84874784074 scopus 로고    scopus 로고
    • COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining
    • doi:10.1371/journal.pgen.1003276.
    • Lemmens BB, Johnson NM, Tijsterman M. 2013. COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining. PLoS Genet. 9:e1003276. doi:10.1371/journal.pgen.1003276.
    • (2013) PLoS Genet. , vol.9
    • Lemmens, B.B.1    Johnson, N.M.2    Tijsterman, M.3
  • 57
    • 0030811331 scopus 로고    scopus 로고
    • Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae
    • Prinz S, Amon A, Klein F. 1997. Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146:781-795.
    • (1997) Genetics , vol.146 , pp. 781-795
    • Prinz, S.1    Amon, A.2    Klein, F.3
  • 58
    • 20744454423 scopus 로고    scopus 로고
    • Srs2 and Sgs1 DNA helicases associate with Mre11 in different sub-complexes following check point activation and CDK1-mediated Srs2 phosphorylation
    • Chiolo I, Carotenuto W, Maffioletti G, Petrini JH, Foiani M, Liberi G. 2005. Srs2 and Sgs1 DNA helicases associate with Mre11 in different sub-complexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Mol. Cell. Biol. 25:5738-5751.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5738-5751
    • Chiolo, I.1    Carotenuto, W.2    Maffioletti, G.3    Petrini, J.H.4    Foiani, M.5    Liberi, G.6
  • 60
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 61
    • 79954417810 scopus 로고    scopus 로고
    • NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans
    • Stergiou L, Eberhard R, Doukoumetzidis K, Hengartner MO. 2011. NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans. Cell Death Differ. 18:897-906.
    • (2011) Cell Death Differ. , vol.18 , pp. 897-906
    • Stergiou, L.1    Eberhard, R.2    Doukoumetzidis, K.3    Hengartner, M.O.4


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