DNA methylation inhibitors, 5-azacytidine and zebularine potentiate the transdifferentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes

Cardiovascular Therapeutics

Volumn 31, Issue 4, 2013, Pages 201-209

  Naeem, Nadia ^a   Haneef, Kanwal ^a   Kabir, Nurul ^a   Iqbal, Hana'a ^a   Jamall, Siddiqua ^a   Salim, Asmat ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

5 azacytidine; Cardiomyocytes; Demethylating agent; Mesenchymal stem cells; Transdifferentiation; Zebularine

Indexed keywords

AZACITIDINE; MESSENGER RNA; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TROPONIN T; ZEBULARINE;

ANIMAL CELL; ARTICLE; CELL FUSION; CELL TRANSDIFFERENTIATION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; FLOW CYTOMETRY; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

5-AZACYTIDINE; CARDIOMYOCYTES; DEMETHYLATING AGENT; MESENCHYMAL STEM CELLS; TRANSDIFFERENTIATION; ZEBULARINE;

ANIMALS; AZACITIDINE; BONE MARROW CELLS; CELL FUSION; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTIDINE; DNA METHYLATION; DNA MODIFICATION METHYLASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MALE; MESENCHYMAL STROMAL CELLS; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSCRIPTION FACTORS; TROPONIN T;

EID: 84880646802     PISSN: 17555914     EISSN: 17555922     Source Type: Journal    
DOI: 10.1111/j.1755-5922.2012.00320.x     Document Type: Article

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