Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone

Journal of Molecular Biology

Volumn 286, Issue 2, 1999, Pages 389-401

  Hurd, Paul J ^a   Whitmarsh, Alan J ^a   Baldwin, Geoffrey S ^a   Kelly, Sharon M ^a   Waltho, Jonathan P ^a   Price, Nicholas C ^a   Connolly, Bernard A ^a   Hornby, David P ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

DNA methyltransferase; Inhibitor; Methylation; Nucleotide analogue; Pyrimidinone

Indexed keywords

CYSTEINE; DNA METHYLTRANSFERASE; DOUBLE STRANDED DNA; GUANINE; N ETHYLMALEIMIDE; PYRIMIDINONE DERIVATIVE; SERINE; THREONINE; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL;

EID: 0033582720     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2491     Document Type: Article

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