메뉴 건너뛰기




Volumn 11, Issue SUPPL.1, 2013, Pages 122-128

The role of the laboratory in treatment with new oral anticoagulants

Author keywords

Anticoagulants; Apixaban; Dabigatran; Laboratory; Rivaroxaban

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; DABIGATRAN ETEXILATE; LOW MOLECULAR WEIGHT HEPARIN; RIVAROXABAN; SERINE PROTEINASE;

EID: 84880603678     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12227     Document Type: Review
Times cited : (70)

References (48)
  • 1
    • 84860536853 scopus 로고    scopus 로고
    • The role of structural information in the discovery of direct thrombin and factor Xa inhibitors
    • Nar H. The role of structural information in the discovery of direct thrombin and factor Xa inhibitors. Trends Pharmacol Sci 2012; 33: 279-88.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 279-288
    • Nar, H.1
  • 8
    • 0029023726 scopus 로고
    • Can overall results of clinical trials be applied to all patients?
    • Rothwell PM. Can overall results of clinical trials be applied to all patients? Lancet 1995; 345: 1616-19.
    • (1995) Lancet , vol.345 , pp. 1616-1619
    • Rothwell, P.M.1
  • 9
    • 78650011217 scopus 로고    scopus 로고
    • Monitoring new oral antithrombotics: what we should know before we can decide
    • Al Dieri R, Hemker HC. Monitoring new oral antithrombotics: what we should know before we can decide. J Thromb Haemost 2010; 8: 2833-5.
    • (2010) J Thromb Haemost , vol.8 , pp. 2833-2835
    • Al Dieri, R.1    Hemker, H.C.2
  • 10
    • 84876192857 scopus 로고    scopus 로고
    • Measuring oral direct inhibitors of thrombin and factor Xa: a recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
    • Baglin T, Hillarp A, Tripodi A, Elalamy I, Buller H, Ageno W. Measuring oral direct inhibitors of thrombin and factor Xa: a recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. J Thromb Haemost 2013; 11: 756-60.
    • (2013) J Thromb Haemost , vol.11 , pp. 756-760
    • Baglin, T.1    Hillarp, A.2    Tripodi, A.3    Elalamy, I.4    Buller, H.5    Ageno, W.6
  • 11
    • 84880580791 scopus 로고    scopus 로고
    • Summary of product characteristics. Dabigatran.Accessed 1 January 2013.
    • Summary of product characteristics. Dabigatran. http://wwwmedicinesorguk/emc/medicine/24839. 2012. Accessed 1 January 2013.
    • (2012)
  • 12
    • 84860528205 scopus 로고    scopus 로고
    • Impact of dabigatran on a large panel of routine or specific coagulation assays. Laboratory recommendations for monitoring of dabigatran etexilate
    • Douxfils J, Mullier F, Robert S, Chatelain C, Chatelain B, Dogne JM. Impact of dabigatran on a large panel of routine or specific coagulation assays. Laboratory recommendations for monitoring of dabigatran etexilate. Thromb Haemost 2012; 107: 985-97.
    • (2012) Thromb Haemost , vol.107 , pp. 985-997
    • Douxfils, J.1    Mullier, F.2    Robert, S.3    Chatelain, C.4    Chatelain, B.5    Dogne, J.M.6
  • 13
    • 33750023407 scopus 로고    scopus 로고
    • Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis
    • Liesenfeld KH, Schafer HG, Troconiz IF, Tillmann C, Eriksson BI, Stangier J. Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis. Br J Clin Pharmacol 2006; 62: 527-37.
    • (2006) Br J Clin Pharmacol , vol.62 , pp. 527-537
    • Liesenfeld, K.H.1    Schafer, H.G.2    Troconiz, I.F.3    Tillmann, C.4    Eriksson, B.I.5    Stangier, J.6
  • 15
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haertter S, Liesenfeld KH, Wienen W, Feuring M, Clemens A. Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010; 103: 1116-27.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • van Ryn, J.1    Stangier, J.2    Haertter, S.3    Liesenfeld, K.H.4    Wienen, W.5    Feuring, M.6    Clemens, A.7
  • 16
    • 79960798870 scopus 로고    scopus 로고
    • Potential inaccuracy of point-of-care INR in dabigatran-treated patients
    • Baruch L, Sherman O. Potential inaccuracy of point-of-care INR in dabigatran-treated patients. Ann Pharmacother 2011; 45: e40.
    • (2011) Ann Pharmacother , vol.45
    • Baruch, L.1    Sherman, O.2
  • 17
    • 84863811351 scopus 로고    scopus 로고
    • Dabigatran falsely elevates point of care international normalized ratio results
    • De Remer CE, Gujral JS, Thornton JW, Sorrentino RA. Dabigatran falsely elevates point of care international normalized ratio results. Am J Med 2011; 124: e5-6.
    • (2011) Am J Med , vol.124
    • De Remer, C.E.1    Gujral, J.S.2    Thornton, J.W.3    Sorrentino, R.A.4
  • 18
    • 84860548394 scopus 로고    scopus 로고
    • Plasma-diluted thrombin time to measure dabigatran concentrations during dabigatran etexilate therapy
    • Avecilla ST, Ferrell C, Chandler WL, Reyes M. Plasma-diluted thrombin time to measure dabigatran concentrations during dabigatran etexilate therapy. Am J Clin Pathol 2012; 137: 572-4.
    • (2012) Am J Clin Pathol , vol.137 , pp. 572-574
    • Avecilla, S.T.1    Ferrell, C.2    Chandler, W.L.3    Reyes, M.4
  • 19
    • 84856593171 scopus 로고    scopus 로고
    • Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
    • Stangier J, Feuring M. Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran. Blood Coagul Fibrinolysis 2012; 23: 138-43.
    • (2012) Blood Coagul Fibrinolysis , vol.23 , pp. 138-143
    • Stangier, J.1    Feuring, M.2
  • 20
    • 84871744380 scopus 로고    scopus 로고
    • The effect of dabigatran on select specialty coagulation assays
    • Adcock DM, Gosselin R, Kitchen S, Dwyre DM. The effect of dabigatran on select specialty coagulation assays. Am J Clin Pathol 2013; 139: 102-9.
    • (2013) Am J Clin Pathol , vol.139 , pp. 102-109
    • Adcock, D.M.1    Gosselin, R.2    Kitchen, S.3    Dwyre, D.M.4
  • 21
    • 84867826077 scopus 로고    scopus 로고
    • Measuring rivaroxaban in a clinical laboratory setting, using common coagulation assays, Xa inhibition and thrombin generation
    • Molenaar PJ, Dinkelaar J, Leyte A. Measuring rivaroxaban in a clinical laboratory setting, using common coagulation assays, Xa inhibition and thrombin generation. Clin Chem Lab Med 2012; 50: 1799-807.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1799-1807
    • Molenaar, P.J.1    Dinkelaar, J.2    Leyte, A.3
  • 22
    • 77954497588 scopus 로고    scopus 로고
    • The paradoxical stimulation by a reversible thrombin inhibitor of thrombin generation in plasma measured with thrombinography is caused by alpha-macroglobulin-thrombin
    • Wagenvoord RJ, Deinum J, Elg M, Hemker HC. The paradoxical stimulation by a reversible thrombin inhibitor of thrombin generation in plasma measured with thrombinography is caused by alpha-macroglobulin-thrombin. J Thromb Haemost 2010; 8: 1281-9.
    • (2010) J Thromb Haemost , vol.8 , pp. 1281-1289
    • Wagenvoord, R.J.1    Deinum, J.2    Elg, M.3    Hemker, H.C.4
  • 23
    • 84860733455 scopus 로고    scopus 로고
    • The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters
    • Green L, Lawrie AS, Patel R, Stephens RC, Mackie IJ, Chitolie A, Haddad FS, Machin SJ. The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters. Thromb Res 2012; 130: 775-9.
    • (2012) Thromb Res , vol.130 , pp. 775-779
    • Green, L.1    Lawrie, A.S.2    Patel, R.3    Stephens, R.C.4    Mackie, I.J.5    Chitolie, A.6    Haddad, F.S.7    Machin, S.J.8
  • 24
    • 80052485992 scopus 로고    scopus 로고
    • Rivaroxaban: population pharmacokinetic analyses in patients treated for acute deep vein thrombosis and exposure simulations in patients with atrial fibrillation treated for stroke prevention
    • Mueck W, Lensing AW, Agnelli G, Decousus H, Prandoni P, Misselwitz F. Rivaroxaban: population pharmacokinetic analyses in patients treated for acute deep vein thrombosis and exposure simulations in patients with atrial fibrillation treated for stroke prevention. Clin Pharmacokinet 2011; 50: 675-86.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 675-686
    • Mueck, W.1    Lensing, A.W.2    Agnelli, G.3    Decousus, H.4    Prandoni, P.5    Misselwitz, F.6
  • 25
    • 51349095537 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement
    • Mueck W, Borris LC, Dahl OE, Haas S, Huisman MV, Kakkar AK, Kalebo P, Muelhofer E, Misselwitz F, Eriksson BI. Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement. Thromb Haemost 2008; 100: 453-61.
    • (2008) Thromb Haemost , vol.100 , pp. 453-461
    • Mueck, W.1    Borris, L.C.2    Dahl, O.E.3    Haas, S.4    Huisman, M.V.5    Kakkar, A.K.6    Kalebo, P.7    Muelhofer, E.8    Misselwitz, F.9    Eriksson, B.I.10
  • 26
    • 84880620724 scopus 로고    scopus 로고
    • Summary of product characteristics. Rivaroxaban. Accessed 1 January 2013.
    • Summary of product characteristics. Rivaroxaban. http://wwwxareltocom/html/downloads/Xarelto-Prescribing_Information-Nov-2012pdf. 2012. Accessed 1 January 2013.
    • (2012)
  • 27
    • 84870240173 scopus 로고    scopus 로고
    • Assessment of the impact of rivaroxaban on coagulation assays: laboratory recommendations for the monitoring of rivaroxaban and review of the literature
    • Douxfils J, Mullier F, Loosen C, Chatelain C, Chatelain B, Dogne JM. Assessment of the impact of rivaroxaban on coagulation assays: laboratory recommendations for the monitoring of rivaroxaban and review of the literature. Thromb Res 2012; 130: 956-66.
    • (2012) Thromb Res , vol.130 , pp. 956-966
    • Douxfils, J.1    Mullier, F.2    Loosen, C.3    Chatelain, C.4    Chatelain, B.5    Dogne, J.M.6
  • 29
    • 78649736882 scopus 로고    scopus 로고
    • Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay
    • Barrett YC, Wang Z, Frost C, Shenker A. Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay. Thromb Haemost 2010; 104: 1263-71.
    • (2010) Thromb Haemost , vol.104 , pp. 1263-1271
    • Barrett, Y.C.1    Wang, Z.2    Frost, C.3    Shenker, A.4
  • 31
    • 84877040380 scopus 로고    scopus 로고
    • Measurement of dabigatran and rivaroxaban in primary prevention of venous thromboembolism in 106 patients, who have undergone major orthopedic surgery: an observational study
    • Samama MM, Guinet C, Le Flem L, Ninin E, Debue JM. Measurement of dabigatran and rivaroxaban in primary prevention of venous thromboembolism in 106 patients, who have undergone major orthopedic surgery: an observational study. J Thromb Thrombolysis 2013; 35: 140-6.
    • (2013) J Thromb Thrombolysis , vol.35 , pp. 140-146
    • Samama, M.M.1    Guinet, C.2    Le Flem, L.3    Ninin, E.4    Debue, J.M.5
  • 33
    • 84862146631 scopus 로고    scopus 로고
    • Report of the Subcommittee of Control of Anticoagulation on the determination of the anticoagulant effects of rivaroxaban
    • Harenberg J, Marx S, Weiss C, Kramer R, Samama M, Schulman S. Report of the Subcommittee of Control of Anticoagulation on the determination of the anticoagulant effects of rivaroxaban. J Thromb Haemost 2012; 10: 1433-6.
    • (2012) J Thromb Haemost , vol.10 , pp. 1433-1436
    • Harenberg, J.1    Marx, S.2    Weiss, C.3    Kramer, R.4    Samama, M.5    Schulman, S.6
  • 34
  • 35
    • 84856293397 scopus 로고    scopus 로고
    • Evaluation of the prothrombin time for measuring rivaroxaban plasma concentrations using calibrators and controls: results of a multicenter field trial
    • Samama MM, Contant G, Spiro TE, Perzborn E, Le Flem L, Guinet C, Gourmelin Y, Martinoli JL. Evaluation of the prothrombin time for measuring rivaroxaban plasma concentrations using calibrators and controls: results of a multicenter field trial. Clin Appl Thromb Hemost 2012; 18: 150-8.
    • (2012) Clin Appl Thromb Hemost , vol.18 , pp. 150-158
    • Samama, M.M.1    Contant, G.2    Spiro, T.E.3    Perzborn, E.4    Le Flem, L.5    Guinet, C.6    Gourmelin, Y.7    Martinoli, J.L.8
  • 36
    • 79955480110 scopus 로고    scopus 로고
    • Coagulation parameters in patients receiving dabigatran etexilate or rivaroxaban: two observational studies in patients undergoing total hip or total knee replacement
    • Freyburger G, Macouillard G, Labrouche S, Sztark F. Coagulation parameters in patients receiving dabigatran etexilate or rivaroxaban: two observational studies in patients undergoing total hip or total knee replacement. Thromb Res 2011; 127: 457-65.
    • (2011) Thromb Res , vol.127 , pp. 457-465
    • Freyburger, G.1    Macouillard, G.2    Labrouche, S.3    Sztark, F.4
  • 37
    • 34147147085 scopus 로고    scopus 로고
    • In vitro inhibition of thrombin generation, after tissue factor pathway activation, by the oral, direct factor Xa inhibitor rivaroxaban
    • Gerotziafas GT, Elalamy I, Depasse F, Perzborn E, Samama MM. In vitro inhibition of thrombin generation, after tissue factor pathway activation, by the oral, direct factor Xa inhibitor rivaroxaban. J Thromb Haemost 2007; 5: 886-8.
    • (2007) J Thromb Haemost , vol.5 , pp. 886-888
    • Gerotziafas, G.T.1    Elalamy, I.2    Depasse, F.3    Perzborn, E.4    Samama, M.M.5
  • 38
    • 84864370719 scopus 로고    scopus 로고
    • Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers
    • Marlu R, Hodaj E, Paris A, Albaladejo P, Crackowski JL, Pernod G. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers. Thromb Haemost 2012; 108: 217-24.
    • (2012) Thromb Haemost , vol.108 , pp. 217-224
    • Marlu, R.1    Hodaj, E.2    Paris, A.3    Albaladejo, P.4    Crackowski, J.L.5    Pernod, G.6
  • 40
    • 84867577449 scopus 로고    scopus 로고
    • The in vitro anticoagulant effect of rivaroxaban in children
    • Attard C, Monagle P, Kubitza D, Ignjatovic V. The in vitro anticoagulant effect of rivaroxaban in children. Thromb Res 2012; 130: 804-7.
    • (2012) Thromb Res , vol.130 , pp. 804-807
    • Attard, C.1    Monagle, P.2    Kubitza, D.3    Ignjatovic, V.4
  • 41
    • 84880624855 scopus 로고    scopus 로고
    • Summary of product characteristics. Apixaban. Accessed 1 January 2013.
    • Summary of product characteristics. Apixaban. http://ec.europa.eu/health/documents/community-register/2011/20110518102349/anx_102349_en.pdf. 2011. Accessed 1 January 2013.
    • (2011)
  • 42
    • 84859937545 scopus 로고    scopus 로고
    • Reversal of antithrombotic agents
    • Bauer KA. Reversal of antithrombotic agents. Am J Hematol 2012; 87(Suppl. 1): S119-26.
    • (2012) Am J Hematol , vol.87 , Issue.SUPPL. 1
    • Bauer, K.A.1
  • 44
    • 84859178003 scopus 로고    scopus 로고
    • How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch
    • Schulman S, Crowther MA. How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch. Blood 2012; 119: 3016-23.
    • (2012) Blood , vol.119 , pp. 3016-3023
    • Schulman, S.1    Crowther, M.A.2
  • 45
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 2011; 124: 1573-9.
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3    Meijers, J.C.4    Buller, H.R.5    Levi, M.6
  • 46
    • 84865793090 scopus 로고    scopus 로고
    • Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate
    • Lambourne MD, Eltringham-Smith LJ, Gataiance S, Arnold DM, Crowther MA, Sheffield WP. Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate. J Thromb Haemost 2012; 10: 1830-40.
    • (2012) J Thromb Haemost , vol.10 , pp. 1830-1840
    • Lambourne, M.D.1    Eltringham-Smith, L.J.2    Gataiance, S.3    Arnold, D.M.4    Crowther, M.A.5    Sheffield, W.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.