Analysis of tear cytokines and clinical correlations in Sjögren syndrome dry eye patients and non-Sjögren syndrome dry eye patients

American Journal of Ophthalmology

Volumn 156, Issue 2, 2013, Pages

  Lee, Sang Yeop ^a   Han, Soo Jung ^a   Nam, Sang Min ^b   Yoon, Sang Chul ^a   Ahn, Ji Min ^c   Kim, Tae Im ^a   Kim, Eung Kweon ^a   Seo, Kyoung Yul ^a  

^a Yonsei University College of Medicine   (South Korea)

^b CHA University   (South Korea)

^c Siloan Eye Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FLUORESCEIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; DRY EYE; FEMALE; HUMAN; LACRIMAL FLUID; MALE; OCULAR SURFACE DISEASE INDEX; PRIORITY JOURNAL; PROSPECTIVE STUDY; RATING SCALE; SCHIRMER STRIP; SCORING SYSTEM; SJOEGREN SYNDROME; TEAR FILM BREAKUP TIME; VISUAL SYSTEM PARAMETERS;

EID: 84880573496     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2013.04.003     Document Type: Article

References (40)

1. C.G. Begley, R.L. Chalmers, and L. Abetz The relationship between habitual patient-reported symptoms and clinical signs among patients with dry eye of varying severity Invest Ophthalmol Vis Sci 44 11 2003 4753 4761
2. The definition of classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye Workshop(2007) Ocul Surf 5 2 2007 75 92
3. E. Goto, Y. Yagi, Y. Matsumoto, and K. Tsubota Impaired functional visual acuity of dry eye patients Am J Ophthalmol 133 2 2002 181 186
4. S. Vitale, L.A. Goodman, G.F. Reed, and J.A. Smith Comparison of the NEI-VFQ and OSDI questionnaires in patients with Sjögren's syndrome-related dry eye Health Qual Life Outcomes 2 2004 44
5. S.K. Chauhan, and R. Dana Role of Th17 cells in the immunopathogenesis of dry eye disease Mucoral Immunol 2 4 2009 375 376
6. X. Zheng, C.S. de Paiva, D.Q. Li, W.J. Farley, and S.C. Pflugfelder Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathway Invest Ophthalmol Vis Sci 51 6 2010 3083 3091
7. H. Lam, L. Bleiden, C.S. de Paiva, W. Farley, M.E. Stern, and S.C. Pflugfelder Tear cytokine profiles in dysfunctional tear syndrome Am J Ophthalmol 147 2 2009 198 205
8. K.C. Yoon, I.Y. Jeong, Y.G. Park, and S.Y. Yang Interleukin-6 and tumor necrosis factor-alpha levels in tears of patients with dry eye syndrome Cornea 26 4 2007 431 437
9. A. Enriquez-de-Salamanca, E. Castellanos, and M.E. Stern Tear cytokine and chemokine analysis and clinical correlations in evaporative-type dry eye disease Mol Vis 16 2010 862 873
10. M.L. Massingale, X. Li, M. Vallabhajosyula, D. Chen, Y. Wei, and P.A. Asbell Analysis of inflammatory cytokines in the tears of dry eye patients Cornea 28 9 2009 1023 1027
11. C.S. Paiva, and S.C. Pflugfelder Rationale for anti-inflammatory therapy in dry eye syndrome Arg Bras Oftalmol 71 2008 89 95
12. G.D. Kymionis, D.I. Bouzoukis, V.F. Diakonis, and C. Siganos Treatment of chronic dry eye: focus on cyclosporine Clin Ophthalmol 2 4 2008 829 836
13. W. Yao, R.S. Davidson, V.D. Durairaj, and C.D. Gelston Dry eye syndrome: an update in office management Am J Med 124 11 2011 1016 1018
14. Y. Okada, K. Ikeda, and O. Yamanaka TNF alpha suppression of corneal epithelium migration Mol Vis 13 2007 1428 1435
15. K. Kimura, S. Teranishi, K. Fukuda, K. Kawamoto, and T. Nishida Delayed disruption of barrier function in cultured human corneal epithelial cells induced by tumor necrosis factor-alpha in a manner dependent on NF-kappaB Invest Ophthalmol Vis Sci 49 2 2008 565 571
16. S.K. Chauhan, J. El Annan, and T. Ecoiffier Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression J Immunol 182 3 2009 1247 1252
17. X. Zheng, F. Bian, and P. Ma Induction of Th17 differentiation by corneal epithelial-derived cytokines J Cell Physiol 222 1 2010 95 102
18. C. Vitali, S. Bombardieri, and R. Jonsson Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group Ann Rheum Dis 61 6 2002 554 558
19. N. Delaleu, M.V. Jonsson, S. Appel, and R. Jonsson New concepts in the pathogenesis of Sjögren's syndrome Rheum Dis Clin North Am 34 4 2008 833 845
20. A.J. Bron, V.E. Evans, and J.A. Smith Grading of corneal and conjunctival staining in the context of other dry eye tests Cornea 22 7 2003 640 650
21. R.M. Schiffman, M.D. Christianson, G. Jacobsen, J.D. Hirsch, and B.L. Reis Reliability and validity of the Ocular Surface Disease Index Arch Ophthalmol 118 5 2000 615 621
22. F. Ozcura, S. Aydin, and M.R. Helvaci Ocular surface disease index for the diagnosis of dry eye syndrome Ocul Immunol Inflamm 15 5 2007 389 393
23. G.E. Katsifis, S. Rekka, N.M. Moutsopoulos, S. Pillemer, and S.M. Wahl Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis Am J Pathol 175 3 2009 1167 1177
24. A. Sakai, Y. Sugawara, T. Kuroishi, T. Sasano, and S. Sugawara Identification of IL-18 and Th17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17 mediated secretion of inflammatory cytokines from salivary gland cells by IL-18 J Immunol 181 4 2008 2898 2906
25. N. Roescher, P.P. Tak, and G.G. Illei Cytokines in Sjögren's syndrome: potential therapeutic targets Ann Rheum Dis 69 6 2010 945 948
26. R.L. Coffman Origins of the T(H)1-T(H)2 model: a personal perspective Nat Immunol 7 6 2006 539 541
27. K.D. Moudgil, and D. Choubey Cytokines in autoimmunity: role in induction, regulation, and treatment J Interferon Cytokine Res 31 10 2011 695 703
28. S.C. Pflugfelder, D. Jones, Z. Ji, A. Afonso, and D. Monroy Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca Curr Eye Res 19 3 1999 201 211
29. M. Tishler, I. Yaron, O. Geyer, I. Shirazi, E. Naftaliev, and M. Yaron Elevated tear interleukin-6 levels in patients with Sjögren syndrome Ophthalmology 105 12 1998 2327 2329
30. M. Pertovaara, J. Antonen, and M. Hurme Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome Ann Rheum Dis 65 5 2006 666 670
31. M.H. Kang, M.K. Kim, H.J. Lee, H.I. Lee, W.R. Wee, and J.H. Lee Interleukin-17 in various ocular surface inflammatory diseases J Korean Med Sci 26 7 2011 938 944
32. M. Ziolkowska, A. Koc, and G. Luszczykiewicz High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism J Immunol 164 5 2000 2832 2838
33. B.D. Sullivan, D. Whitmer, and K.K. Nichols An objective approach to dry eye disease severity Invest Ophthalmol Vis Sci 51 12 2010 6125 6130
34. K.K. Nichols, J.J. Nichols, and G.L. Mitchell The lack of association between signs and symptoms in patients with dry eye disease Cornea 23 8 2004 762 770
35. L. Luo, D.Q. Li, and S.C. Pflugfelder Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways Cornea 26 4 2007 452 460
36. L.E. Harrington, R.D. Hatton, and P.R. Mangan Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Nat Immunol 6 11 2005 1123 1132
37. R.M. Onishi, and S.L. Gaffen Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease Immunology 129 3 2010 311 321
38. C.S. De Paiva, S. Chotikavanich, and S.B. Pangelinan IL-17 disrupts corneal barrier following desiccating stress Mucosal Immunol 2 3 2009 243 253
39. M. Fujita, T. Igarashi, T. Kurai, M. Sakane, S. Yoshino, and H. Takahashi Correlation between dry eye and rheumatoid arthritis activity Am J Ophthalmol 140 5 2005 808 813
40. M.A. Lemp Dry eye (keratoconjunctivitis sicca), rheumatoid arthritis, and Sjogren's syndrome Am J Ophthalmol 140 5 2005 898 899 Health and Welfare