Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease

Heart and Vessels

Volumn 28, Issue 2, 2013, Pages 268-275

  Sciacca, Sergio ^a   Pilato, Michele ^a   Mazzoccoli, Gianluigi ^b   Pazienza, Valerio ^b   Vinciguerra, Manlio ^c  

^a MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^b CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

Author keywords

Bicuspid aortic disease; Notch; Sirtuin 1

Indexed keywords

JAGGED1; MESSENGER RNA; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6; SIRTUIN 7; TRANSCRIPTION FACTOR HES 1;

ADULT; AORTA VALVE DISEASE; ARTICLE; ASCENDING AORTA; BICUSPID AORTIC VALVE; BLOOD VESSEL BIOPSY; COHORT ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE INTERACTION; GENETIC ASSOCIATION; HES1 GENE; HEY1 GENE; HEY2 GENE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; NOTCH REGULATED ANKYRIN REPEAT PROTEIN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; SIRTUIN 1 GENE; SIRTUIN 2 GENE; SIRTUIN 3 GENE; SIRTUIN 4 GENE; SIRTUIN 5 GENE; SIRTUIN 6 GENE; SIRTUIN 7 GENE; WESTERN BLOTTING;

AGED; AORTA; AORTIC VALVE; BIOLOGICAL MARKERS; BIOPSY; BLOTTING, WESTERN; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION REGULATION; HEART VALVE DISEASES; HUMANS; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIRTUIN 1;

EID: 84880573093     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-012-0238-5     Document Type: Article

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