Induction of apoptosis through caspase-independent or caspase-9-dependent pathway in mouse and human osteosarcoma cells by a new nitroxyl spin-labeled derivative of podophyllotoxin

Apoptosis

Volumn 18, Issue 6, 2013, Pages 727-738

  Yang, Tuan Min ^a   Qi, She Ning ^b   Zhao, Na ^b   Yang, Yu Jie ^c   Yuan, Hu Qin ^d   Zhang, Bing ^a   Jin, Shuai ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c First Hospital of PLA   (China)

^d Tumor Hospital of Gansu Province   (China)

Author keywords

Apoptosis; Cell cycle; Derivative; Osteosarcoma; Podophyllotoxin; Proliferation; RNAi technique

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; CYTOCHROME C; DOXORUBICIN; ENDONUCLEASE G; ETOPOSIDE; METHOTREXATE; PODOPHYLLOTOXIN DERIVATIVE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SPIN LABELING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 9; CASPASE INHIBITORS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA FRAGMENTATION; DRUG THERAPY, COMBINATION; ENDODEOXYRIBONUCLEASES; ETOPOSIDE; HUMANS; MICE; OSTEOSARCOMA; PODOPHYLLOTOXIN; SPIN LABELS;

EID: 84880572473     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0819-5     Document Type: Article

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