Perioperative oxygen supplementation and surgical site infection after cesarean delivery: A randomized trial

Obstetrics and Gynecology

Volumn 122, Issue 1, 2013, Pages 79-84

  Duggal, Neena ^a   Poddatorri, Vineela ^b   Noroozkhani, Sara ^b   Siddik Ahmad, R Iram ^b   Caughey, Aaron B ^b  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFAZOLIN; CLINDAMYCIN; OXYGEN;

ADULT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CESAREAN SECTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETES MELLITUS; ENDOMETRITIS; FEMALE; HOSPITALIZATION; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; PARITY; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERIUM; RACE; RANDOMIZED CONTROLLED TRIAL; SUPPLEMENTATION; SURGICAL INFECTION; WOUND INFECTION;

ADULT; CESAREAN SECTION; DOUBLE-BLIND METHOD; ENDOMETRITIS; FEMALE; HUMANS; OXYGEN; PREGNANCY; PROSPECTIVE STUDIES; SURGICAL WOUND INFECTION; TREATMENT OUTCOME;

EID: 84880571389     PISSN: 00297844     EISSN: 1873233X     Source Type: Journal    
DOI: 10.1097/AOG.0b013e318297ec6c     Document Type: Article

References (17)

1. Dellinger EP. Increasing inspired oxygen to decrease surgical site infection. JAMA 2005;294:2091-2.
2. Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999;20:725-30.
3. Bratzler DW, Houck PM, Richards C, Steele L, Dellinger EP, Fry DE, et al. Use of antimicrobial prophylaxis for major surgery: baseline results from the National Surgical Infection Prevention Project. Arch Surg 2005;140:174-82.
4. Cardoso Del Monte MC, Pinto Neto AM. Postdischarge surveillance following cesarean section: the incidence of surgical site infection and associated factors. Am J Infect Control 2010;38:467-72.
5. Ghuman M, Rohlandt D, Joshy G, Lawrenson R. Post-caesarean section surgical site infection: rate and risk factors. N Z Med J 2011;124:32-6.
6. Gong SP, Guo HX, Zhou HZ, Chen L, Yu YH. Morbidity and risk factors for surgical site infection following cesarean section in Guangdong Province, China. J Obstet Gynaecol Res 2012; 38:509-15.
7. Olsen MA, Butler AM, Willers DM, Gross GA, Hamilton BH, Fraser VJ. Attributable costs of surgical site infection and endometritis after low transverse cesarean delivery. Infect Control Hosp Epidemiol 2010;31:276-82.
8. Belda FJ, Aguilera L, Garcia de la Asuncion J, Alberti J, Vicente R, Ferrandiz L, et al. Supplemental perioperative oxygen and the risk of surgical wound infection. JAMA 2005;294: 2035-42.
9. Hopf HW, Hunt TK, West JM, Blomquist P, Goodson WH, Jensen JA, et al. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg 1997;132: 997-1004; discussion 1005.
10. Allen DB, Maguire JJ, Mahdavian M, Wicke C, Marcocci L, Scheuenstuhl H, et al. Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms. Arch Surg 1997;132:991-6.
11. Greif R, Akca O, Horn E-P, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 2000;342:161-7.
12. Khaw KS, Wang CC, Ngan Kee WD, Pang CP, Rogers MS. Effects of high inspired oxygen fraction during elective caesarean section under spinal anaesthesia on maternal and fetal oxygenation and lipid peroxidation. Br J Anaesth 2002;88:18-23.
13. Backe SK, Lyons G. Oxygen and elective caesarean section. Br J Anaesth 2002;88:4-5.
14. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128-40.
15. Pryor KO, Fahey TJ III, Lien CA, Goldstein PA. Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population. JAMA 2004;291:79-87.
16. Gardella C, Goltra LB, Laschansky E, Drolette L, Magaret A, Chadwick HS, et al. High-concentration supplemental perioperative oxygen to reduce the incidence of postcesarean surgical site infection. Obstet Gynecol 2008;112: 545-52.
17. Scifres CM, Leighton BL, Fogertey PJ, Macones GA, Stamilio DM. Supplemental oxygen for the prevention of postcesarean infectious morbidity: a randomized controlled trial. Am J Obstet Gynecol 2011;205:267.e1-9.