Increasing inspired oxygen to decrease surgical site infection: Time to shift the quality improvement research paradigm

JAMA

Volumn 294, Issue 16, 2005, Pages 2091-2092

  Dellinger, E Patchen ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL RESEARCH; EDITORIAL; HEALTH CARE SYSTEM; HUMAN; INFECTION RISK; MEDICAL SOCIETY; OXYGEN CONSUMPTION; OXYGEN TENSION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK REDUCTION; SURGICAL INFECTION; SURGICAL TECHNIQUE; INHALATIONAL DRUG ADMINISTRATION; NOTE; PERIOPERATIVE PERIOD;

OXYGEN;

ADMINISTRATION, INHALATION; HUMANS; OXYGEN; PERIOPERATIVE CARE; SURGICAL WOUND INFECTION;

EID: 27244439040     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.294.16.2091     Document Type: Editorial

References (23)

1. Kirkland KB, Briggs JP, Trivette SL, et al. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol. 1999;20:725-730.
2. Bratzler DW, Houck PM, Richards C, et al. Use of antimicrobial prophylaxis for major surgery: baseline results from the National Surgical Infection Prevention Project. Arch Surg. 2005;140:174-182.
3. Anaya DA, Dellinger EP. Surgical infections and choice of antibiotics. In: Townsend CM Jr, ed. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. Philadelphia, Pa: Elsevier Saunders; 2004:257-282.
4. Belda FJ, Aguilera L, García de la Asunción J, et al. Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial. JAMA. 2005;294:2035-2042.
5. Burke J. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery. 1961;50:161-168.
6. Babior BM. Oxygen-dependent microbial killing by phagocytes (first of two parts). N Engl J Med. 1978;298:659-668.
7. Hohn DC, MacKay RD, Halliday B, Hunt TK. Effect of O2 tension on microbicidal function of leukocytes in wounds and in vitro. Surg Forum. 1976;27:18-20.
8. Allen DB, Maguire JJ, Mahdavian M, et al. Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms. Arch Surg. 1997;132:991-996.
9. Hunt TK, Linsey M, Grislis H, et al. The effect of differing ambient oxygen tensions on wound infection. Ann Surg. 1975;181:35-39.
10. Jonsson K, Hunt TK, Mathes SJ. Oxygen as an isolated variable influences resistance to infection. Ann Surg. 1988;208:783-787.
11. Knighton DR, Fiegel VD, Halverson T, et al. Oxygen as an antibiotic: the effect of inspired oxygen on bacterial clearance. Arch Surg. 1990;125:97-100.
12. Knighton DR, Halliday B, Hunt TK. Oxygen as an antibiotic: the effect of inspired oxygen on infection. Arch Surg. 1984;119:199-204.
13. Knighton DR, Halliday B, Hunt TK. Oxygen as an antibiotic: a comparison of the effects of inspired oxygen concentration and antibiotic administration on in vivo bacterial clearance. Arch Surg. 1986;121:191-195.
14. Hopf HW, Hunt TK, West JM, et al. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg. 1997;132:997-1004.
15. Ikeda T, Tayefeh F, Sessler DI, et al. Local radiant heating increases subcutaneous oxygen tension. Am J Surg. 1998;175:33-37.
16. Plattner O, Akca O, Herbst F, et al. The influence of 2 surgical bandage systems on wound tissue oxygen tension. Arch Surg. 2000;135:818-822.
17. Rabkin JM, Hunt TK. Local heat increases blood flow and oxygen tension in wounds. Arch Surg. 1987;122:221-225.
18. Tayefeh F, Kurz A, Sessler DI, et al. Thermoregulatory vasodilation increases the venous partial pressure of oxygen. Anesth Analg. 1997;85:657-662.
19. Kurz A, Sessler DI, Lenhardt R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization: Study of Wound Infection and Temperature Group. N Engl J Med. 1996;334:1209-1215.
20. Melling AC, Ali B, Scott EM, Leaper DJ. Effects of preoperative warming on the incidence of wound infection after clean surgery: a randomised controlled trial. Lancet. 2001;358:876-880.
21. Greif R, Akca O, Horn EP, et al. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med. 2000;342:161-167.
22. Pryor KO, Fahey TJ III, Lien CA, Goldstein PA. Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. JAMA. 2004;291:79-87.
23. Dellinger EP, Hausmann SM, Bratzler DW, et al. Hospitals collaborate to decrease surgical site infections. Am J Surg. 2005;190:9-15.