-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
2
-
-
0032542216
-
A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability
-
Shen SX, Weaver Z, Xu X, et al. A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability. Oncogene 1998;17:3115-24.
-
(1998)
Oncogene
, vol.17
, pp. 3115-3124
-
-
Shen, S.X.1
Weaver, Z.2
Xu, X.3
-
3
-
-
33645003172
-
BRCA1: Cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
-
Deng CX. BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 2006;34:1416-26.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1416-1426
-
-
Deng, C.X.1
-
4
-
-
33646500809
-
BRCA1 regulation of transcription
-
Rosen EM, Fan S, Ma Y. BRCA1 regulation of transcription. Cancer Lett 2006;236:175-85.
-
(2006)
Cancer Lett
, vol.236
, pp. 175-185
-
-
Rosen, E.M.1
Fan, S.2
Ma, Y.3
-
5
-
-
33749000596
-
The role of BRCA1 in transcriptional regulation and cell cycle control
-
Mullan PB, Quinn JE, Harkin DP. The role of BRCA1 in transcriptional regulation and cell cycle control. Oncogene 2006;25:5854-63.
-
(2006)
Oncogene
, vol.25
, pp. 5854-5863
-
-
Mullan, P.B.1
Quinn, J.E.2
Harkin, D.P.3
-
6
-
-
0033618621
-
Association of BRCA1 with the hRad50-11-p95 complex and the DNA damage response
-
Zhong Q, Chen CF, Li S, et al. Association of BRCA1 with the hRad50-11-p95 complex and the DNA damage response. Science 1999;285:747-50.
-
(1999)
Science
, vol.285
, pp. 747-750
-
-
Zhong, Q.1
Chen, C.F.2
Li, S.3
-
7
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
Monteiro AN, August A, Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci U S A 1996;93:13595-9.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
8
-
-
0029830051
-
Transcriptional activation by BRCA1
-
Chapman MS, Verma IM. Transcriptional activation by BRCA1. Nature 1996;382:678-9.
-
(1996)
Nature
, vol.382
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
9
-
-
0012668180
-
Transactivation of repair genes by BRCA1
-
El-Deiry WS. Transactivation of repair genes by BRCA1. Cancer Biol Ther 2002;1:490-1.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 490-491
-
-
El-Deiry, W.S.1
-
10
-
-
10344230981
-
A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint
-
Wang RH, Yu H, Deng CX. A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint. Proc Natl Acad Sci U S A 2004;101:17108-13.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17108-17113
-
-
Wang, R.H.1
Yu, H.2
Deng, C.X.3
-
11
-
-
33745713176
-
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature
-
Furuta S, Wang JM, Wei S, et al. Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature. Cancer Cell 2006;10:13-24.
-
(2006)
Cancer Cell
, vol.10
, pp. 13-24
-
-
Furuta, S.1
Wang, J.M.2
Wei, S.3
-
12
-
-
0028950999
-
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
-
Thompson ME, Jensen RA, Obermiller PS, Page DL, Holt JT. Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat Genet 1995;9:444-50.
-
(1995)
Nat Genet
, vol.9
, pp. 444-450
-
-
Thompson, M.E.1
Jensen, R.A.2
Obermiller, P.S.3
Page, D.L.4
Holt, J.T.5
-
13
-
-
0032953384
-
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas
-
Wilson CA, Ramos L, Villasenor MR, et al. Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat Genet 1999;21:236-40.
-
(1999)
Nat Genet
, vol.21
, pp. 236-240
-
-
Wilson, C.A.1
Ramos, L.2
Villasenor, M.R.3
-
14
-
-
0035397553
-
Prognostic significance of BRCA1 expression in Japanese sporadic breast carcinomas
-
Yang Q, Sakurai T, Mori I, et al. Prognostic significance of BRCA1 expression in Japanese sporadic breast carcinomas. Cancer 2001;92:54-60.
-
(2001)
Cancer
, vol.92
, pp. 54-60
-
-
Yang, Q.1
Sakurai, T.2
Mori, I.3
-
15
-
-
2942536701
-
Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA1 and TP53, in breast cancer is related to tumour grade
-
Ding SL, Sheu LF, Yu JC, et al. Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA1 and TP53, in breast cancer is related to tumour grade. Br J Cancer 2004;90:1995-2001.
-
(2004)
Br J Cancer
, vol.90
, pp. 1995-2001
-
-
Ding, S.L.1
Sheu, L.F.2
Yu, J.C.3
-
17
-
-
0033615623
-
Transcription of BRCA1 is dependent on the formation of a specific protein-DNA complex on the minimal BRCA1 Bi-directional promoter
-
Suen TC, Goss PE. Transcription of BRCA1 is dependent on the formation of a specific protein-DNA complex on the minimal BRCA1 Bi-directional promoter. J Biol Chem 1999;274:31297-304.
-
(1999)
J Biol Chem
, vol.274
, pp. 31297-31304
-
-
Suen, T.C.1
Goss, P.E.2
-
18
-
-
33845505452
-
Selective leukemic cell killing by a novel functional class of thalidomide analogs
-
Ge Y, Montano I, Freebern WJ, et al. Selective leukemic cell killing by a novel functional class of thalidomide analogs. Blood 2006;108:4126-35.
-
(2006)
Blood
, vol.108
, pp. 4126-4135
-
-
Ge, Y.1
Montano, I.2
Freebern, W.J.3
-
19
-
-
0038719698
-
Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter
-
BakerKM, Wei G, Schaffner AE, Ostrowski MC. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. J Biol Chem 2003;278:17876-84.
-
(2003)
J Biol Chem
, vol.278
, pp. 17876-17884
-
-
Baker, K.M.1
Wei, G.2
Schaffner, A.E.3
Ostrowski, M.C.4
-
21
-
-
33751084058
-
Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites
-
Bindra RS, Glazer PM. Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. Cancer Biol Ther 2006;5:1400-7.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1400-1407
-
-
Bindra, R.S.1
Glazer, P.M.2
-
22
-
-
29244439933
-
Hypoxia-induced downregulation of BRCA1 expression by E2Fs
-
Bindra RS, Gibson SL, Meng A, et al. Hypoxia-induced downregulation of BRCA1 expression by E2Fs. Cancer Res 2005;65:11597-604.
-
(2005)
Cancer Res
, vol.65
, pp. 11597-11604
-
-
Bindra, R.S.1
Gibson, S.L.2
Meng, A.3
-
23
-
-
73349142390
-
Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes
-
Byun JS, Wong MM, Cui W, et al. Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. Proc Natl Acad Sci U S A 2009;106:19286-91.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19286-19291
-
-
Byun, J.S.1
Wong, M.M.2
Cui, W.3
-
24
-
-
4143124557
-
Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment
-
Smith JL, Freebern WJ, Collins I, et al. Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment. Proc Natl Acad Sci U S A 2004;101:11554-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 11554-11559
-
-
Smith, J.L.1
Freebern, W.J.2
Collins, I.3
-
25
-
-
23744467035
-
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
-
Yang Z, Yik JH, Chen R, et al. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol Cell 2005;19:535-45.
-
(2005)
Mol Cell
, vol.19
, pp. 535-545
-
-
Yang, Z.1
Yik, J.H.2
Chen, R.3
-
26
-
-
31344436263
-
ChIPOTle: A user-friendly tool for the analysis of ChIP-chip data
-
Buck MJ, Nobel AB, Lieb JD. ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data. Genome Biol 2005;6:R97.
-
(2005)
Genome Biol
, vol.6
-
-
Buck, M.J.1
Nobel, A.B.2
Lieb, J.D.3
-
27
-
-
0037114148
-
Cross-regulation of T cell growth factor expression by p53 and the Tax oncogene
-
Chaudhry S, Freebern WJ, Smith JL, Butscher WG, Haggerty CM, Gardner K. Cross-regulation of T cell growth factor expression by p53 and the Tax oncogene. J Immunol 2002;169:6767-78.
-
(2002)
J Immunol
, vol.169
, pp. 6767-6778
-
-
Chaudhry, S.1
Freebern, W.J.2
Smith, J.L.3
Butscher, W.G.4
Haggerty, C.M.5
Gardner, K.6
-
28
-
-
0031961944
-
Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2
-
Butscher WG, Powers C, Olive M, Vinson C, Gardner K. Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2. J Biol Chem 1998;273:552-60.
-
(1998)
J Biol Chem
, vol.273
, pp. 552-560
-
-
Butscher, W.G.1
Powers, C.2
Olive, M.3
Vinson, C.4
Gardner, K.5
-
30
-
-
27744489743
-
BRCA1 regulates gene expression for orderly mitotic progression
-
Bae I, Rih JK, Kim HJ, et al. BRCA1 regulates gene expression for orderly mitotic progression. Cell Cycle 2005;4:1641-66.
-
(2005)
Cell Cycle
, vol.4
, pp. 1641-1666
-
-
Bae, I.1
Rih, J.K.2
Kim, H.J.3
-
31
-
-
0033609057
-
BRCA1 interacts with components of the histone deacetylase complex
-
Yarden RI, Brody LC. BRCA1 interacts with components of the histone deacetylase complex. Proc Natl Acad Sci U S A 1999;96:4983-8.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 4983-4988
-
-
Yarden, R.I.1
Brody, L.C.2
-
32
-
-
0142180081
-
E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
-
Oberley MJ, Inman DR, Farnham PJ. E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9. J Biol Chem 2003;278:42466-76.
-
(2003)
J Biol Chem
, vol.278
, pp. 42466-42476
-
-
Oberley, M.J.1
Inman, D.R.2
Farnham, P.J.3
-
33
-
-
0030838793
-
BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases
-
Wang H, Shao N, Ding QM, Cui J, Reddy ES, Rao VN. BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases. Oncogene 1997;15:143-57.
-
(1997)
Oncogene
, vol.15
, pp. 143-157
-
-
Wang, H.1
Shao, N.2
Ding, Q.M.3
Cui, J.4
Reddy, E.S.5
Rao, V.N.6
-
34
-
-
0034635478
-
Regulation of BRCA1 expression by the Rb-E2F pathway
-
Wang A, Schneider-Broussard R, Kumar AP, MacLeod MC, Johnson DG. Regulation of BRCA1 expression by the Rb-E2F pathway. J Biol Chem 2000;275:4532-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 4532-4536
-
-
Wang, A.1
Schneider-Broussard, R.2
Kumar, A.P.3
MacLeod, M.C.4
Johnson, D.G.5
-
35
-
-
0029820095
-
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
-
Hofmann F, Martelli F, Livingston DM, Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev 1996;10:2949-59.
-
(1996)
Genes Dev
, vol.10
, pp. 2949-2959
-
-
Hofmann, F.1
Martelli, F.2
Livingston, D.M.3
Wang, Z.4
-
36
-
-
0032516238
-
Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1
-
Halaban R, Cheng E, Zhang Y, Mandigo CE, Miglarese MR. Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1. Oncogene 1998;16:2489-501.
-
(1998)
Oncogene
, vol.16
, pp. 2489-2501
-
-
Halaban, R.1
Cheng, E.2
Zhang, Y.3
Mandigo, C.E.4
Miglarese, M.R.5
-
37
-
-
0032580310
-
Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents
-
Andres JL, Fan S, Turkel GJ, et al. Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents. Oncogene 1998;16:2229-41.
-
(1998)
Oncogene
, vol.16
, pp. 2229-2241
-
-
Andres, J.L.1
Fan, S.2
Turkel, G.J.3
-
38
-
-
0031872850
-
Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to Adriamycin and ultraviolet radiation
-
Fan S, Twu NF, Wang JA, et al. Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to Adriamycin and ultraviolet radiation. Int J Cancer 1998;77:600-9.
-
(1998)
Int J Cancer
, vol.77
, pp. 600-609
-
-
Fan, S.1
Twu, N.F.2
Wang, J.A.3
-
40
-
-
0033931881
-
Kinetics of BRCA1 regulation in response to UVC radiation
-
Clarkin CE, Zhang H, Weber BL. Kinetics of BRCA1 regulation in response to UVC radiation. Cell Mol Life Sci 2000;57:1126-34.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 1126-1134
-
-
Clarkin, C.E.1
Zhang, H.2
Weber, B.L.3
-
41
-
-
33947359114
-
E2F6 negatively regulates ultraviolet-induced apoptosis via modulation of BRCA1
-
Yang WW, Wang ZH, Zhu Y, Yang HT. E2F6 negatively regulates ultraviolet-induced apoptosis via modulation of BRCA1. Cell Death Differ 2007;14:807-17.
-
(2007)
Cell Death Differ
, vol.14
, pp. 807-817
-
-
Yang, W.W.1
Wang, Z.H.2
Zhu, Y.3
Yang, H.T.4
-
42
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
MacLachlan TK, Takimoto R, El-Deiry WS. BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol Cell Biol 2002;22:4280-92.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
43
-
-
8644281106
-
A common set of gene regulatory networks links metabolism and growth inhibition
-
Cam H, Balciunaite E, Blais A, et al. A common set of gene regulatory networks links metabolism and growth inhibition. Mol Cell 2004;16:399-411.
-
(2004)
Mol Cell
, vol.16
, pp. 399-411
-
-
Cam, H.1
Balciunaite, E.2
Blais, A.3
-
44
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu X, Wu LC, Bowcock AM, Aronheim A, Baer R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J Biol Chem 1998;273:25388-92.
-
(1998)
J Biol Chem
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
45
-
-
34249854866
-
A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase
-
Horwitz AA, Affar EB, Heine GF, Shi Y, Parvin JD. A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase. Proc Natl Acad Sci U S A 2007;104:6614-9.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6614-6619
-
-
Horwitz, A.A.1
Affar, E.B.2
Heine, G.F.3
Shi, Y.4
Parvin, J.D.5
-
46
-
-
1842364973
-
Localization of BRCA1 and a splice variant identifies the nuclear localization signal
-
Thakur S, Zhang HB, Peng Y, et al. Localization of BRCA1 and a splice variant identifies the nuclear localization signal. Mol Cell Biol 1997;17:444-52.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 444-452
-
-
Thakur, S.1
Zhang, H.B.2
Peng, Y.3
-
47
-
-
0034946638
-
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumori-genesis
-
Xu X, Qiao W, Linke SP, et al. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumori-genesis. Nat Genet 2001;28:266-71.
-
(2001)
Nat Genet
, vol.28
, pp. 266-271
-
-
Xu, X.1
Qiao, W.2
Linke, S.P.3
|