α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling

Journal of Biological Chemistry

Volumn 288, Issue 29, 2013, Pages 20883-20895

  Ouberai, Myriam M ^a   Wang, Juan ^b   Swann, Marcus J ^b   Galvagnion, Celine ^a   Guilliams, Tim ^a   Dobson, Christopher M ^a   Welland, Mark E ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Farfield Group Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; HELICAL STRUCTURES; LATERAL EXPANSION; MEMBRANE INTERACTIONS; MEMBRANE REMODELING; PACKING DEFECT; PLANAR MEMBRANES; VESICLE TRAFFICKING;

DEFECTS;

LIPIDS;

ALPHA SYNUCLEIN; PHOSPHOLIPID;

ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; GENE INSERTION; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE STRUCTURE; OPTICAL BIOSENSOR; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ALPHA-SYNUCLEIN; ATOMIC FORCE MICROSCOPY; DUAL POLARIZATION INTERFEROMETRY; LIPID PACKING DEFECTS; MEMBRANE BILAYER; MEMBRANE BIOPHYSICS; MEMBRANE REMODELING; MEMBRANE STRUCTURE; PROTEIN-LIPID INTERACTIONS;

ALPHA-SYNUCLEIN; INTERFEROMETRY; LIPID BILAYERS; MELITTEN; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MODELS, MOLECULAR; PERMEABILITY; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; TISSUE EXTRACTS; UNILAMELLAR LIPOSOMES;

EID: 84880521916     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.478297     Document Type: Article

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