Influence of chlorine substitution on the hydrolytic stability of biaryl ether nucleoside adducts produced by phenolic toxins

Journal of Organic Chemistry

Volumn 78, Issue 14, 2013, Pages 7176-7185

  Kuska, Michael S ^a   Majdi Yazdi, Mohadeseh ^b   Witham, Aaron A ^a   Dahlmann, Heidi A ^c   Sturla, Shana J ^c   Wetmore, Stacey D ^b   Manderville, Richard A ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF LETHBRIDGE   (Canada)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-CATALYZED HYDROLYSIS; DEOXYGUANOSINE (DG); ELECTRONWITHDRAWING; ELECTROSPRAY MASS SPECTROMETRY; HYDROLYTIC STABILITY; PHENOXYL RADICAL; RATE OF HYDROLYSIS; SPECTROPHOTOMETRIC TITRATIONS;

BIOMOLECULES; CHLORINE; CHLORINE COMPOUNDS; ETHERS; HYDROLYSIS; METABOLITES; PROTONATION; SULFONATION;

ALKALINITY;

8 PHENOXY 2' DEOXYGUANOSINE; CHLORINE; DEOXYGUANOSINE; ETHER; NUCLEOSIDE DERIVATIVE; OXYGEN; PHENOLIC TOXIN; PYRIDINE DERIVATIVE; TOXIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHLORINATION; CRYSTAL STRUCTURE; DEGLYCOSYLATION; DENSITY FUNCTIONAL THEORY; ELECTROSPRAY MASS SPECTROMETRY; HYDROLYSIS; KINETICS; METABOLISM; PH; PKA; PROTON TRANSPORT; SPECTROPHOTOMETRY; SUBSTITUTION REACTION; SYNTHESIS;

ACIDS; CATALYSIS; CHLORINE; DEOXYGUANOSINE; ETHERS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; PHENOL; QUANTUM THEORY;

EID: 84880515382     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo401122j     Document Type: Article

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