Formation of 8-nitroguanine in tobacco cigarette smokers and in tobacco smoke-exposed Wistar rats

Chemico-Biological Interactions

Volumn 140, Issue 1, 2002, Pages 67-80

  Hsieh, Yih Shou ^a   Chen, Bi Chiou ^a   Shiow, Song Jui ^a   Wang, Hsue Chun ^a   Hsu, Jeng Dong ^b   Wang, Chau Jong ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

8 nitroguanine; DNA of lymphocytes and lung tissues; Gaseous nitrogen oxide; Smoke exopsed human and rats

Indexed keywords

8 NITROGUANINE; CIGARETTE SMOKE; DNA; GUANINE DERIVATIVE; NITRIC OXIDE; NITRITE; TOBACCO SMOKE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL LEVEL; CIGARETTE SMOKING; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; EXPOSURE; LUNG CANCER; LYMPHOCYTE; MALE; NONHUMAN; RAT; TOBACCO;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; DNA ADDUCTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUANINE; HUMANS; LUNG; LYMPHOCYTES; MALE; MIDDLE AGED; NITROGEN OXIDES; RATS; RATS, WISTAR; SMOKE;

ANIMALIA; NICOTIANA TABACUM; RATTUS NORVEGICUS;

EID: 0037140385     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00018-2     Document Type: Article

References (40)

1. Tobacco use and nasopharyngeal carcinoma in a cohort of US veterans
2. Smoking and cancer mortality among US veterans: A 26-year follow-up
3. Tobacco and cancer: Epidemiology and the laboratory
4. Free-radical chemistry of cigarette smoke and its toxicological implications
5. Generation of hydrogen peroxide and superoxide anion radical from cigarette smoke
6. Electron-spin resonance study of mainstream and sidestream cigarette smoke: Nature of the free radicals in gas-phase smoke and in cigarette tar
7. Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury
8. Free radical biology: Xenobiotics, cancer, and aging
9. Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound
10. Free radical chemistry of cigarette smoke and its implication in human cancer
11. Heme oxygenase expression in Swiss 3T3 cells following exposure to aqueous cigarette smoke fractions
12. Expression of c-fos in quiescent Swiss 3T3 cells exposed to aqueous cigarette smoke fractions
13. Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/MEK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke
14. Studies on the ability of smoke from different types of cigarettes to induce DNA single-strand breaks in cultured human cells
15. Cigarette tar causes single-strand breaks in DNA
16. Cigarette smoke-induced DNA damage in cultured human lung cells: Role of hydroxyl radicals and endonuclease activation
17. Cigarette smoke induces DNA single-strand breaks in human cells
18. Aqueous extracts of cigarette tar containing the tar free radical cause DNA nicks in mammalian cells
19. The ESR properties, DNA nicking, and DNA association of aged solutions of catechol versus aqueous extracts of tar from cigarette smoke
20. Increase of a type of oxidative DNA damage, 8-hydroxy-guanine and its repair activity in human leukocytes by cigarette smoking
21. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung
22. Evidence for peroxynitrite as an oxidative stress-inducing compound of aqueous cigarette smoke fractions
23. Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro
24. Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
25. Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA
26. 15N-nitrite in biological fluids
27. N-Nitrosodimethylamine, N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′ deoxyguanosine in liver DNA of male F344 rats
28. Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA
29. Formation of 8-hydroxy residues in DNA by X-irradiation
30. Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco-smoke
31. Chemical constituents and bioactivity of tobacco smoke
32. Chromosomal aberrations and sister-chromatid exchanges induced by gaseous nitrogen oxide in cultured Chinese hamster cells
33. Nitrogen dioxide induces DNA single-strand breaks in cultured Chinese hamster cells
34. Induction of mutations and chromosome aberrations in lung cells following in vivo exposure of rats to nitrogen oxides
35. Comparison between aqueous-phase and gas-phase exposure protocols for determining the mutagenic potential of nitrogen dioxide and the gas fraction of welding fumes
36. DNA damage by nitrite and peroxynitrite: Protection by dietary phenols
37. 8-nitrixanthine, an adduct derived from 2′-deoxyguanosine or DNA reaction with nitryl choride
38. Antioxidant and pro-oxidant actions of flavonoids: Effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxy anion
39. DNA damage in human respiratory tract epithelial cells: Damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals
40. Prolytic origins of major gas phase constituents of cigarette smoke