메뉴 건너뛰기




Volumn 434, Issue 3, 2013, Pages 641-646

Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity

Author keywords

Matrix metalloproteinase; Shear stress; VEGF; VEGFR2

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ILOMASTAT; MATRIX METALLOPROTEINASE; NEUTRALIZING ANTIBODY; PROTEOHEPARAN SULFATE; TYROSINE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN A;

EID: 84880467286     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.134     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 77956597255 scopus 로고    scopus 로고
    • Shear-induced endothelial cell-cell junction inclination
    • B. Melchior, J.A. Frangos, Shear-induced endothelial cell-cell junction inclination, Am. J. Physiol. Cell Physiol. 299 (2010) C621-C629.
    • (2010) Am. J. Physiol. Cell Physiol. , vol.299 , pp. C621-C629
    • Melchior, B.1    Frangos, J.A.2
  • 2
    • 65749118783 scopus 로고    scopus 로고
    • Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex
    • L.A. Otte, K.S. Bell, L. Loufrani, J.C. Yeh, B. Melchior, D.N. Dao, H.Y. Stevens, C.R. White, J.A. Frangos, Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex, J. Physiol. 587 (2009) 2365-2373.
    • (2009) J. Physiol. , vol.587 , pp. 2365-2373
    • Otte, L.A.1    Bell, K.S.2    Loufrani, L.3    Yeh, J.C.4    Melchior, B.5    Dao, D.N.6    Stevens, H.Y.7    White, C.R.8    Frangos, J.A.9
  • 4
    • 0037135988 scopus 로고    scopus 로고
    • Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: Is it a mechanoresponsive molecule?
    • M. Osawa, M. Masuda, K. Kusano, K. Fujiwara, Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?, J Cell Biol. 158 (2002) 773-785.
    • (2002) J Cell Biol. , vol.158 , pp. 773-785
    • Osawa, M.1    Masuda, M.2    Kusano, K.3    Fujiwara, K.4
  • 5
    • 0029822797 scopus 로고    scopus 로고
    • Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction
    • S.R. Gudi, C.B. Clark, J.A. Frangos, Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction, Circ. Res. 79 (1996) 834-839.
    • (1996) Circ. Res. , vol.79 , pp. 834-839
    • Gudi, S.R.1    Clark, C.B.2    Frangos, J.A.3
  • 6
    • 84865153751 scopus 로고    scopus 로고
    • Galphaq/11-mediated intracellular calcium responses to retrograde flow in endothelial cells
    • B. Melchior, J.A. Frangos, Galphaq/11-mediated intracellular calcium responses to retrograde flow in endothelial cells, Am. J. Physiol. Cell Physiol. 303 (2012) C467-C473.
    • (2012) Am. J. Physiol. Cell Physiol. , vol.303 , pp. C467-C473
    • Melchior, B.1    Frangos, J.A.2
  • 7
    • 0033603352 scopus 로고    scopus 로고
    • Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc
    • K.D. Chen, Y.S. Li, M. Kim, S. Li, S. Yuan, S. Chien, J.Y. Shyy, Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc, J. Biol. Chem. 274 (1999) 18393-18400.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18393-18400
    • Chen, K.D.1    Li, Y.S.2    Kim, M.3    Li, S.4    Yuan, S.5    Chien, S.6    Shyy, J.Y.7
  • 8
    • 0035970008 scopus 로고    scopus 로고
    • Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands
    • S. Jalali, M.A. del Pozo, K. Chen, H. Miao, Y. Li, M.A. Schwartz, J.Y. Shyy, S. Chien, Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands, Proc. Natl. Acad. Sci. USA 98 (2001) 1042-1046.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1042-1046
    • Jalali, S.1    Del Pozo, M.A.2    Chen, K.3    Miao, H.4    Li, Y.5    Schwartz, M.A.6    Shyy, J.Y.7    Chien, S.8
  • 10
    • 0032696285 scopus 로고    scopus 로고
    • A flow-activated chloride-selective membrane current in vascular endothelial cells
    • A.I. Barakat, E.V. Leaver, P.A. Pappone, P.F. Davies, A flow-activated chloride-selective membrane current in vascular endothelial cells, Circ. Res. 85 (1999) 820-828.
    • (1999) Circ. Res. , vol.85 , pp. 820-828
    • Barakat, A.I.1    Leaver, E.V.2    Pappone, P.A.3    Davies, P.F.4
  • 11
    • 33644850341 scopus 로고    scopus 로고
    • Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress
    • E.A. Osborn, A. Rabodzey, C.F. Dewey Jr., J.H. Hartwig, Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress, Am. J. Physiol. Cell Physiol. 290 (2006) C444-C452.
    • (2006) Am. J. Physiol. Cell Physiol. , vol.290 , pp. C444-C452
    • Osborn, E.A.1    Rabodzey, A.2    Dewey, C.F.3    Hartwig, J.H.4
  • 12
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • B. Millauer, S. Wizigmann-Voos, H. Schnurch, R. Martinez, N.P. Moller, W. Risau, A. Ullrich, High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis, Cell 72 (1993) 835-846.
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6    Ullrich, A.7
  • 14
    • 0035355472 scopus 로고    scopus 로고
    • A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
    • T. Takahashi, S. Yamaguchi, K. Chida, M. Shibuya, A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells, EMBO J. 20 (2001) 2768-2778.
    • (2001) EMBO J. , vol.20 , pp. 2768-2778
    • Takahashi, T.1    Yamaguchi, S.2    Chida, K.3    Shibuya, M.4
  • 16
    • 22344437713 scopus 로고    scopus 로고
    • Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
    • S. Lee, S.M. Jilani, G.V. Nikolova, D. Carpizo, M.L. Iruela-Arispe, Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors, J. Cell Biol. 169 (2005) 681-691.
    • (2005) J. Cell Biol. , vol.169 , pp. 681-691
    • Lee, S.1    Jilani, S.M.2    Nikolova, G.V.3    Carpizo, D.4    Iruela-Arispe, M.L.5
  • 17
    • 0034635483 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7)
    • W.H. Yu, J.F. Woessner Jr., Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7), J. Biol. Chem. 275 (2000) 4183-4191.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4183-4191
    • Yu, W.H.1    Woessner, J.F.2
  • 21
    • 0042358676 scopus 로고    scopus 로고
    • Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase
    • Z.G. Jin, H. Ueba, T. Tanimoto, A.O. Lungu, M.D. Frame, B.C. Berk, Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase, Circ. Res. 93 (2003) 354-363.
    • (2003) Circ. Res. , vol.93 , pp. 354-363
    • Jin, Z.G.1    Ueba, H.2    Tanimoto, T.3    Lungu, A.O.4    Frame, M.D.5    Berk, B.C.6
  • 22
    • 0021972202 scopus 로고
    • Flow effects on prostacyclin production by cultured human endothelial cells
    • J.A. Frangos, S.G. Eskin, L.V. McIntire, C.L. Ives, Flow effects on prostacyclin production by cultured human endothelial cells, Science 227 (1985) 1477-1479.
    • (1985) Science , vol.227 , pp. 1477-1479
    • Frangos, J.A.1    Eskin, S.G.2    McIntire, L.V.3    Ives, C.L.4
  • 23
    • 84856285863 scopus 로고    scopus 로고
    • Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription
    • G. E, Y. Cao, S. Bhattacharya, S. Dutta, E. Wang, D. Mukhopadhyay, Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription, J. Biol. Chem. 287 (2012) 3029-3041.
    • (2012) J. Biol. Chem. , vol.287 , pp. 3029-3041
    • E, G.1    Cao, Y.2    Bhattacharya, S.3    Dutta, S.4    Wang, E.5    Mukhopadhyay, D.6
  • 24
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • N. Prenzel, E. Zwick, H. Daub, M. Leserer, R. Abraham, C. Wallasch, A. Ullrich, EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF, Nature 402 (1999) 884-888.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 25
    • 0041440927 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
    • G. Seghezzi, S. Patel, C.J. Ren, A. Gualandris, G. Pintucci, E.S. Robbins, R.L. Shapiro, A.C. Galloway, D.B. Rifkin, P. Mignatti, Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis, J. Cell Biol. 141 (1998) 1659-1673.
    • (1998) J. Cell Biol. , vol.141 , pp. 1659-1673
    • Seghezzi, G.1    Patel, S.2    Ren, C.J.3    Gualandris, A.4    Pintucci, G.5    Robbins, E.S.6    Shapiro, R.L.7    Galloway, A.C.8    Rifkin, D.B.9    Mignatti, P.10
  • 26
    • 0027236142 scopus 로고
    • Expression of vascular endothelial growth factor by cultured endothelial cells from brain microvessels
    • A. Ladoux, C. Frelin, Expression of vascular endothelial growth factor by cultured endothelial cells from brain microvessels, Biochem. Biophys. Res. Commun. 194 (1993) 799-803.
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , pp. 799-803
    • Ladoux, A.1    Frelin, C.2
  • 27
    • 0036479305 scopus 로고    scopus 로고
    • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: Role of protein kinase A
    • Y.C. Boo, G. Sorescu, N. Boyd, I. Shiojima, K. Walsh, J. Du, H. Jo, Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A, J. Biol. Chem. 277 (2002) 3388-3396.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3388-3396
    • Boo, Y.C.1    Sorescu, G.2    Boyd, N.3    Shiojima, I.4    Walsh, K.5    Du, J.6    Jo, H.7
  • 28
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • S. Dimmeler, I. Fleming, B. Fisslthaler, C. Hermann, R. Busse, A.M. Zeiher, Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation, Nature 399 (1999) 601-605.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 29
    • 0029876376 scopus 로고    scopus 로고
    • The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases
    • J.M. Whitelock, A.D. Murdoch, R.V. Iozzo, P.A. Underwood, The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases, J. Biol. Chem. 271 (1996) 10079-10086.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10079-10086
    • Whitelock, J.M.1    Murdoch, A.D.2    Iozzo, R.V.3    Underwood, P.A.4
  • 30
    • 0037183997 scopus 로고    scopus 로고
    • Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165
    • G. Hashimoto, I. Inoki, Y. Fujii, T. Aoki, E. Ikeda, Y. Okada, Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165, J. Biol. Chem. 277 (2002) 36288-36295.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36288-36295
    • Hashimoto, G.1    Inoki, I.2    Fujii, Y.3    Aoki, T.4    Ikeda, E.5    Okada, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.