-
2
-
-
70350482699
-
Cellular and systemic effects of anthrax lethal toxin and edema toxin
-
Moayeri M, Leppla SH. 2009. Cellular and systemic effects of anthrax lethal toxin and edema toxin. Mol. Aspects Med. 30:439-455.
-
(2009)
Mol. Aspects Med.
, vol.30
, pp. 439-455
-
-
Moayeri, M.1
Leppla, S.H.2
-
4
-
-
84861214708
-
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
-
doi:10.1371/journal.ppat.1002638
-
Levinsohn JL, Newman ZL, Hellmich KA, Fattah R, Getz MA, Liu S, Sastalla I, Leppla SH, Moayeri M. 2012. Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. PLoS Pathog. 8:e1002638. doi:10.1371/journal.ppat.1002638.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Levinsohn, J.L.1
Newman, Z.L.2
Hellmich, K.A.3
Fattah, R.4
Getz, Ma.5
Liu, S.6
Sastalla, I.7
Leppla, S.H.8
Moayeri, M.9
-
6
-
-
77953497798
-
Advances in the development of nextgeneration anthrax vaccines
-
Friedlander AM, Little SF. 2009. Advances in the development of nextgeneration anthrax vaccines. Vaccine 27(Suppl. 4):D28-D32.
-
(2009)
Vaccine
, vol.27
, Issue.SUPPL. 4
-
-
Friedlander, A.M.1
Little, S.F.2
-
7
-
-
84856417753
-
Phase 1 study of a recombinant mutant protective antigen of Bacillus anthracis
-
Bellanti JA, Lin FY, Chu C, Shiloach J, Leppla SH, Benavides GA, Karpas A, Moayeri M, Guo C, Robbins JB, Schneerson R. 2012. Phase 1 study of a recombinant mutant protective antigen of Bacillus anthracis. Clin. Vaccine Immunol. 19:140-145.
-
(2012)
Clin. Vaccine Immunol.
, vol.19
, pp. 140-145
-
-
Bellanti, J.A.1
Lin, F.Y.2
Chu, C.3
Shiloach, J.4
Leppla, S.H.5
Benavides, G.A.6
Karpas, A.7
Moayeri, M.8
Guo, C.9
Robbins, J.B.10
Schneerson, R.11
-
8
-
-
77955084872
-
Use of anthrax vaccine in the United States; recommendation of the Advisory Committee on Immunization Practices, 2009
-
Centers for Disease Control and Prevention
-
Centers for Disease Control and Prevention. 2010. Use of anthrax vaccine in the United States; recommendation of the Advisory Committee on Immunization Practices, 2009.MMWRMorb. Mortal. Wkly. Rep. 59:1-30.
-
(2010)
MMWRMorb. Mortal. Wkly. Rep.
, vol.59
, pp. 1-30
-
-
-
9
-
-
77954907327
-
-
U. S. Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research, and Center for Biologics Evaluation and Research. Rockville, MD
-
U. S. Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research, and Center for Biologics Evaluation and Research. 2009. Guidance for industry; animal models- essential elements to address efficacy under the animal rule. FDA, Rockville, MD. http://www.fda.gov/cber/guidelines .htm.
-
(2009)
Guidance for Industry; Animal Models- Essential Elements to Address Efficacy under the Animal Rule
-
-
-
10
-
-
84866296461
-
Anthrax vaccine-induced antibodies provide cross-species prediction of survival to aerosol challenge
-
doi:10.1126/scitranslmed.3004073
-
Fay MP, Follmann DA, Lynn F, Schiffer JM, Stark GV, Kohberger R, Quinn CP, Nuzum EO. 2012. Anthrax vaccine-induced antibodies provide cross-species prediction of survival to aerosol challenge. Sci. Transl. Med. 4151ra126. doi:10.1126/scitranslmed.3004073.
-
(2012)
Sci. Transl. Med.
-
-
Fay, M.P.1
Follmann, D.A.2
Lynn, F.3
Schiffer, J.M.4
Stark, G.V.5
Kohberger, R.6
Quinn, C.P.7
Nuzum, E.O.8
-
11
-
-
79955113963
-
Anthrax vaccination induced anti-lethal factor IgG: Fine specificity and neutralizing capacity
-
Crowe SR, Garman L, Engler RJ, Farris AD, Ballard JD, Harley JB, James JA. 2011. Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine 29:3670-3678.
-
(2011)
Vaccine
, vol.29
, pp. 3670-3678
-
-
Crowe, S.R.1
Garman, L.2
Engler, R.J.3
Farris, A.D.4
Ballard, J.D.5
Harley, J.B.6
James, J.A.7
-
12
-
-
34447525273
-
Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine
-
Hepburn MJ, Hugh DE, Simpson AJ, Brenneman KE, Bailey N, Wilkinson L, Hornby R, Mateczun AJ, Bell MG, Baillie LW. 2007. Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine. Vaccine 25:6089-6097.
-
(2007)
Vaccine
, vol.25
, pp. 6089-6097
-
-
Hepburn, M.J.1
De Hugh2
Simpson, A.J.3
Brenneman, K.E.4
Bailey, N.5
Wilkinson, L.6
Hornby, R.7
Mateczun, A.J.8
Bell, M.G.9
Baillie, L.W.10
-
13
-
-
84861655341
-
Human monoclonal antibodies generated following vaccination with AVAprovide neutralization by blocking furin cleavage but not by preventing oligomerization
-
Smith K, Crowe SR, Garman L, Guthridge CJ, Muther JJ, McKee E, Zheng NY, Farris AD, Guthridge JM, Wilson PC, James JA. 2012. Human monoclonal antibodies generated following vaccination with AVAprovide neutralization by blocking furin cleavage but not by preventing oligomerization. Vaccine 30:4276-4283.
-
(2012)
Vaccine
, vol.30
, pp. 4276-4283
-
-
Smith, K.1
Crowe, S.R.2
Garman, L.3
Guthridge, C.J.4
Muther, J.J.5
McKee, E.6
Zheng, N.Y.7
Farris, A.D.8
Guthridge, J.M.9
Wilson, P.C.10
James, J.A.11
-
14
-
-
43149106509
-
Neutralizing activity of vaccine-induced antibodies to two Bacillus anthracis toxin components, lethal factor and edema factor
-
Taft SC, Weiss AA. 2008. Neutralizing activity of vaccine-induced antibodies to two Bacillus anthracis toxin components, lethal factor and edema factor. Clin. Vaccine Immunol. 15:71-75.
-
(2008)
Clin. Vaccine Immunol.
, vol.15
, pp. 71-75
-
-
Taft, S.C.1
Weiss, A.A.2
-
15
-
-
47049128494
-
Interlaboratory comparison of results of an anthrax lethal toxin neutralization assay for assessment of functional antibodies in multiple species
-
Omland KS, Brys A, Lansky D, Clement K, Lynn F. 2008. Interlaboratory comparison of results of an anthrax lethal toxin neutralization assay for assessment of functional antibodies in multiple species. Clin. Vaccine Immunol. 15:946-953.
-
(2008)
Clin. Vaccine Immunol.
, vol.15
, pp. 946-953
-
-
Omland, K.S.1
Brys, A.2
Lansky, D.3
Clement, K.4
Lynn, F.5
-
16
-
-
0001676920
-
In vitro correlate of immunity in an animal model of inhalational anthrax
-
Pitt ML, Little S, Ivins BE, Fellows P, Boles J, Barth J, Hewetson J, Friedlander AM. 1999. In vitro correlate of immunity in an animal model of inhalational anthrax. J. Appl. Microbiol. 87:304.
-
(1999)
J. Appl. Microbiol.
, vol.87
, pp. 304
-
-
Pitt, M.L.1
Little, S.2
Ivins, B.E.3
Fellows, P.4
Boles, J.5
Barth, J.6
Hewetson, J.7
Friedlander, A.M.8
-
17
-
-
0345096575
-
Defining a serological correlate of protection in rabbits for a recombinant anthrax vaccine
-
Little SF, Ivins BE, Fellows PF, Pitt ML, Norris SL, Andrews GP. 2004. Defining a serological correlate of protection in rabbits for a recombinant anthrax vaccine. Vaccine 22:422-430.
-
(2004)
Vaccine
, vol.22
, pp. 422-430
-
-
Little, S.F.1
Ivins, B.E.2
Fellows, P.F.3
Pitt, M.L.4
Norris, S.L.5
Andrews, G.P.6
-
18
-
-
1542722948
-
Validation of the anthrax lethal toxin neutralization assay
-
Hering D, Thompson W, Hewetson J, Little S, Norris S, Pace- Templeton J. 2004. Validation of the anthrax lethal toxin neutralization assay. Biologicals 32:17-27.
-
(2004)
Biologicals
, vol.32
, pp. 17-27
-
-
Hering, D.1
Thompson, W.2
Hewetson, J.3
Little, S.4
Norris, S.5
Pace- Templeton, J.6
-
19
-
-
41349113144
-
Standardized, mathematical model-based and validated in vitro analysis of anthrax lethal toxin neutralization
-
Li H, Soroka SD, Taylor TH, Jr, Stamey KL, Stinson KW, Freeman AE, Abramson DR, Desai R, Cronin LX, Oxford JW, Caba J, Pleatman C, Pathak S, Schmidt DS, Semenova VA, Martin SK, Wilkins PP, Quinn CP. 2008. Standardized, mathematical model-based and validated in vitro analysis of anthrax lethal toxin neutralization. J. Immunol. Methods 333: 89-106.
-
(2008)
J. Immunol. Methods
, vol.333
, pp. 89-106
-
-
Li, H.1
Soroka, S.D.2
Taylor, T.H.3
Stamey Jr., K.L.4
Stinson, K.W.5
Freeman, A.E.6
Abramson, D.R.7
Desai, R.8
Cronin, L.X.9
Oxford, J.W.10
Caba, J.11
Pleatman, C.12
Pathak, S.13
Schmidt, D.S.14
Semenova, V.A.15
Martin, S.K.16
Wilkins, P.P.17
Quinn, C.P.18
-
20
-
-
77956417668
-
Analysis of antibody responses to protective antigen-based anthrax vaccines through use of competitive assays
-
Brady RA, Verma A, Meade BD, Burns DL. 2010. Analysis of antibody responses to protective antigen-based anthrax vaccines through use of competitive assays. Clin. Vaccine Immunol. 17:1390-1397.
-
(2010)
Clin. Vaccine Immunol.
, vol.17
, pp. 1390-1397
-
-
Brady, R.A.1
Verma, A.2
Meade, B.D.3
Burns, D.L.4
-
21
-
-
79551471831
-
Reduction of immunogenicity of anthrax vaccines subjected to thermal stress, as measured by a toxin neutralization assay
-
Castelan-Vega J, Corvette L, Sirota L, Arciniega J. 2011. Reduction of immunogenicity of anthrax vaccines subjected to thermal stress, as measured by a toxin neutralization assay. Clin. Vaccine Immunol. 18:349-351.
-
(2011)
Clin. Vaccine Immunol.
, vol.18
, pp. 349-351
-
-
Castelan-Vega, J.1
Corvette, L.2
Sirota, L.3
Arciniega, J.4
-
22
-
-
70349423529
-
The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example
-
Hughes MA, Burns DL, Juris SJ, Tang WJ, Clement KH, Eaton LJ, Kelly-Cirino CD, McKee ML, Powell BS, Bishop BL, Rudge TL, Shine N, Verma A, Willis MS, Morse SA. 2009. The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example. Infect. Immun. 77:4182-4186.
-
(2009)
Infect. Immun.
, vol.77
, pp. 4182-4186
-
-
Hughes, M.A.1
Burns, D.L.2
Juris, S.J.3
Tang, W.J.4
Clement, K.H.5
Eaton, L.J.6
Kelly-Cirino, C.D.7
McKee, M.L.8
Powell, B.S.9
Bishop, B.L.10
Rudge, T.L.11
Shine, N.12
Verma, A.13
Willis, M.S.14
Morse, S.A.15
-
23
-
-
77953154332
-
Comparison of three anthrax toxin neutralization assays
-
Ngundi MM, Meade BD, Lin TL, Tang WJ, Burns DL. 2010. Comparison of three anthrax toxin neutralization assays. Clin. Vaccine Immunol. 17:895-903.
-
(2010)
Clin. Vaccine Immunol.
, vol.17
, pp. 895-903
-
-
Ngundi, M.M.1
Meade, B.D.2
Lin, T.L.3
Tang, W.J.4
Burns, D.L.5
-
24
-
-
67649464197
-
Comparability of ELISA and toxin neutralization to measure immunogenicity of protective antigen in mice, as part of a potency test for anthrax vaccines
-
Parreiras PM, Sirota LA, Wagner LD, Menzies SL, Arciniega JL. 2009. Comparability of ELISA and toxin neutralization to measure immunogenicity of protective antigen in mice, as part of a potency test for anthrax vaccines. Vaccine 27:4537-4542.
-
(2009)
Vaccine
, vol.27
, pp. 4537-4542
-
-
Parreiras, P.M.1
Sirota, L.A.2
Wagner, L.D.3
Menzies, S.L.4
Arciniega, J.L.5
-
25
-
-
55849095820
-
Role of the N-terminal amino acid of Bacillus anthracis lethal factor in lethal toxin cytotoxicity and its effect on the lethal toxin neutralization assay
-
Verma A, Wagner L, Stibitz S, Nguyen N, Guerengomba F, Burns DL. 2008. Role of the N-terminal amino acid of Bacillus anthracis lethal factor in lethal toxin cytotoxicity and its effect on the lethal toxin neutralization assay. Clin. Vaccine Immunol. 15:1737-1741.
-
(2008)
Clin. Vaccine Immunol.
, vol.15
, pp. 1737-1741
-
-
Verma, A.1
Wagner, L.2
Stibitz, S.3
Nguyen, N.4
Guerengomba, F.5
Burns, D.L.6
-
26
-
-
0034049623
-
Optimized production and purification of Bacillus anthracis lethal factor
-
Park S, Leppla SH. 2000. Optimized production and purification of Bacillus anthracis lethal factor. Protein Expr. Purif. 18:293-302.
-
(2000)
Protein Expr. Purif.
, vol.18
, pp. 293-302
-
-
Park, S.1
Leppla, S.H.2
-
27
-
-
51549119044
-
Role of N-terminal amino acids in the potency of anthrax lethal factor
-
doi:10.1371/journal.pone.0003130
-
Gupta PK, Moayeri M, Crown D, Fattah RJ, Leppla SH. 2008. Role of N-terminal amino acids in the potency of anthrax lethal factor. PLoS One 3:e3130. doi:10.1371/journal.pone.0003130.
-
(2008)
PLoS One
, vol.3
-
-
Gupta, P.K.1
Moayeri, M.2
Crown, D.3
Fattah, R.J.4
Leppla, S.H.5
-
28
-
-
80051574871
-
Marked enhancement of the immune response to BioThrax (anthrax vaccine adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers
-
Rynkiewicz D, Rathkopf M, Sim I, Waytes AT, Hopkins RJ, Giri L, DeMuria D, Ransom J, Quinn J, Nabors GS, Nielsen CJ. 2011. Marked enhancement of the immune response to BioThrax (anthrax vaccine adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers. Vaccine 29:6313-6320.
-
(2011)
Vaccine
, vol.29
, pp. 6313-6320
-
-
Rynkiewicz, D.1
Rathkopf, M.2
Sim, I.3
Waytes, A.T.4
Hopkins, R.J.5
Giri, L.6
DeMuria, D.7
Ransom, J.8
Quinn, J.9
Nabors, G.S.10
Nielsen, C.J.11
|