Shear stress-induced Ang II AT1 receptor activation: G-protein dependent and independent mechanisms

Biochemical and Biophysical Research Communications

Volumn 434, Issue 3, 2013, Pages 647-652

  Barauna, Valerio G ^a   Magalhaes, Flávio C ^b   Campos, Luciene C G ^a   Reis, Rosana I ^a   Kunapuli, Satya P ^c   Costa Neto, Claudio M ^a   Miyakawa, Ayumi A ^a   Krieger, Jose E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI   (Brazil)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ang II AT1 receptor; Cell signaling; Mechanotransduction; Shear stress

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; JANUS KINASE 2; PROTEIN KINASE P60; AGTR1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL LINEAGE; CHO CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; INTRACELLULAR SIGNALING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SECOND MESSENGER; SHEAR STRESS; ANIMAL; CHO CELL; CRICETULUS; HAMSTER; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CRICETULUS GRISEUS;

ANIMALS; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; POLYMERASE CHAIN REACTION; RECEPTOR, ANGIOTENSIN, TYPE 1; STRESS, PHYSIOLOGICAL;

MLCS; MLOWN;

EID: 84880456784     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.04.005     Document Type: Article

References (26)

1. P.K. Mehta, K.K. Griendling, Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system, American Journal of Physiology. Cell Physiology 292 (2007) 82-97.
2. B. Zimmerman, A. Beautrait, B. Aguila, R. Charles, E. Escher, A. Claing, et al., Differential-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs, Science Signaling 5 (2012). ra33.
3. R.M. Touyz, C. Berry, Recent advances in angiotensin II signaling, Brazilian J. Med. Biol. Res. Revista Brasileira De Pesquisas Médicas e Biológicas/Sociedade Brasileira De Biofísica 35 (2002) 1001-1015.
4. C. Hahn, M.A. Schwartz, Mechanotransduction in vascular physiology and atherogenesis, Nature Reviews Molecular Cell Biology 10 (2009) 53-62.
5. N. Yasuda, S. Miura, H. Akazawa, T. Tanaka, Y. Qin, Y. Kiya, et al., Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation, EMBO Reports 9 (2008) 179-186.
6. M. Mederos y Schnitzler, U. Storch, T. Gudermann, AT1 receptors as mechanosensors, Current Opinion in Pharmacology 11 (2011) 112-116.
7. Y. Zou, H. Akazawa, Y. Qin, M. Sano, H. Takano, T. Minamino, et al., Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II, Nature Cell Biology 6 (2004) 499-506.
8. K. Rakesh, B. Yoo, I.-M. Kim, N. Salazar, K. Kim, H.A. Rockman, Beta-arrestin-biased agonism of the angiotensin receptor induced by mechanical stress, Science Signaling 3 (2010). ra46.
9. D.G. Tilley, G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function, Circulation Research 109 (2011) 217-230.
10. S.M. Dewire, J.D. Violin, Biased ligands for better cardiovascular drugs: dissecting g-protein-coupled receptor pharmacology, Circulation Research 109 (2011) 205-216.
11. G. Boerrigter, M.W. Lark, E.J. Whalen, D.G. Soergel, J.D. Violin, J.C. Burnett, Cardiorenal actions of TRV120027, a Novel, b-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure, Circulation: Heart Failure (2011) 120027.
12. J.D. Violin, S.M. Dewire, D. Yamashita, D.H. Rominger, L. Nguyen, K. Schiller, et al., Selectively engaging b-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance, The Journal of Pharmacology and Experimental Therapeutics 335 (2010) 572-579.
13. K. Rajagopal, E.J. Whalen, J.D. Violin, J.A. Stiber, P.B. Rosenberg, R.T. Premont, et al., Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes, Proceedings of the National Academy of Sciences of the United States of America 103 (2006) 16284-16289.
14. Z. Gaborik, The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling, Endocrinology 144 (2003) 2220-2228.
15. V.G. Barauna, L.C.G. Campos, A.A. Miyakawa, J.E. Krieger, ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270), PLoS ONE 6 (2011) e22803.
16. V. Bassaneze, V.G. Barauna, C. Lavini-Ramos, J. Kalil, I.T. Schettert, A.A. Miyakawa, et al., Shear stress induces nitric oxide-mediated vascular endothelial growth factor production in human adipose tissue mesenchymal stem cells, Stem Cells and Development 19 (2010) 371-378.
17. S. Hammond, M. Kaplarevic, N. Borth, M.J. Betenbaugh, K.H. Lee, Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org., Biotechnology and Bioengineering 109 (2012) 1353-1356.
18. S. Ahn, S.K. Shenoy, H. Wei, R.J. Lefkowitz, Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor, The Journal of Biological Chemistry 279 (2004) 35518-35525.
19. Z.-G. Jin, H. Ueba, T. Tanimoto, A.O. Lungu, M.D. Frame, B.C. Berk, Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase, Circulation Research 93 (2003) 354-363.
20. A. Makino, E.R. Prossnitz, M. Bünemann, J.M. Wang, W. Yao, G.W. Schmid-Schönbein, G protein-coupled receptors serve as mechanosensors for fluid shear stress in neutrophils, American Journal of Physiology. Cell Physiology 290 (2006) 1633-1639.
21. A.A. Miyakawa, M. de Lourdes Junqueira, J.E. Krieger, Identification of two novel shear stress responsive elements in rat angiotensin I converting enzyme promoter, Physiological Genomics 17 (2004) 107-113.
22. M. Vaughan, G protein-coupled receptors minireview series, The Journal of Biological Chemistry 273 (1998) 17297.
23. W.G. Thomas, Regulation of angiotensin II type 1 (AT1) receptor function, Regulatory Peptides 79 (1999) 9-23.
24. D.F. Guo, Y.L. Sun, P. Hamet, T. Inagami, The angiotensin II type 1 receptor and receptor-associated proteins, Cell Research 11 (2001) 165-180.
25. S.K. Shenoy, R.J. Lefkowitz, Angiotensin II-stimulated signaling through G proteins and beta-arrestin, Science's STKE: Signal Transduction Knowledge Environment (2005). cm14.
26. N. Toda, K. Ayajiki, T. Okamura, Interaction of endothelial nitric oxide and angiotensin in the circulation, Pharmacological Reviews 59 (2007) 54-87.