Regenerative scaffold electrodes for peripheral nerve interfacing

IEEE Transactions on Neural Systems and Rehabilitation Engineering

Volumn 21, Issue 4, 2013, Pages 554-566

  Clements, Isaac P ^a,b   Mukhatyar, Vivek J ^a,c   Srinivasan, Akhil ^a   Bentley, John T ^a,d   Andreasen, Dinal S ^e   Bellamkonda, Ravi V ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b PLEXON INC   (United States)

^c Smith and Nephew Research Centre   (United Kingdom)

^d UNIVERSITY OF MICHIGAN   (United States)

^e GEORGIA TECH RESEARCH INSTITUTE   (United States)

Author keywords

Minimalist; nanofibers; nerve regeneration; neural interfacing; thin films

Indexed keywords

CELLULAR MIGRATION; DORSAL ROOT GANGLIA; EMBEDDED ELECTRODES; MINIMALIST; NERVE REGENERATION; NEURAL INTERFACING; REGENERATIVE ELECTRODES; THIN-FILM ELECTRODE;

ELECTRODES; NANOFIBERS; NEUROLOGY; NEURONS;

ARTIFICIAL LIMBS;

NANOFIBER;

ANIMAL; ARTICLE; BRAIN COMPUTER INTERFACE; CELL COUNT; CELL MOTION; ELECTRODE; ELECTRODE IMPLANT; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; EQUIPMENT; IMMUNOHISTOCHEMISTRY; LEWIS RAT; LIMB; MALE; NERVE FIBER; NERVE REGENERATION; ORGAN CULTURE TECHNIQUE; PERIPHERAL NERVE; PHYSIOLOGY; PROSTHESES AND ORTHOSES; PROSTHESIS; RAT; SPINAL GANGLION; DEVICES;

ANIMALS; AXONS; BRAIN-COMPUTER INTERFACES; CELL COUNT; CELL MOVEMENT; ELECTRIC STIMULATION; ELECTRODES; ELECTRODES, IMPLANTED; ELECTROPHYSIOLOGICAL PROCESSES; EXTREMITIES; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MALE; NANOFIBERS; NERVE REGENERATION; ORGAN CULTURE TECHNIQUES; PERIPHERAL NERVES; PROSTHESES AND IMPLANTS; PROSTHESIS DESIGN; RATS; RATS, INBRED LEW;

EID: 84880434931     PISSN: 15344320     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNSRE.2012.2217352     Document Type: Article

References (67)

1. K. Ziegler-Graham et al., "Estimating the prevalence of limb loss in the United States: 2005 to 2050," Arch. Phys. Med. Rehabil., vol. 89, pp. 422-429, Mar. 2008. (Pubitemid 351273168)
2. G. S. Dhillon et al., "Residual function in peripheral nerve stumps of amputees: Implications for neural control of artificial limbs," J. Hand Surg., vol. 29A, pp. 605-615, Jul. 2004. (Pubitemid 38916703)
3. F. Baldissera et al., "Integration in spinal neuronal systems," in Handbook of Physiology, V. B. Brooks, Ed. Washington, D.C.: Am. Physiol. Soc., 1981, pp. 509-595.
4. R. Poppele and G. Bosco, "Sophisticated spinal contributions to motor control," Trends Neurosci., vol. 26, pp. 269-276, May 2003. (Pubitemid 36556158)
5. P. Rudomin and R. F. Schmidt, "Presynaptic inhibition in the vertebrate spinal cord revisited," Exp. Brain Res., vol. 129, pp. 1-37, Nov. 1999. (Pubitemid 29494837)
6. A. Mannard et al., "Regeneration electrode units - Implants for recording from single peripheral-nerve fibers in freely moving animals," Science, vol. 183, pp. 547-549, 1974.
7. D. J. Edell, "A peripheral-nerve information transducer for amputees - Long-term multichannel recordings from rabbit peripheral- nerves," IEEE Trans. Biomed. Eng., vol. 33, no. 2, pp. 203-214, Feb. 1986. (Pubitemid 16154070)
8. G. T. A. Kovacs et al., "Regeneration microelectrode array for peripheral- nerve recording and stimulation," IEEE Trans. Biomed. Eng., vol. 39, no. 9, pp. 893-902, Sep. 1992. (Pubitemid 23121820)
9. T. Akin et al., "A micromachined silicon sieve electrode for nerve regeneration applications," IEEE Trans. Biomed. Engi., vol. 41, no. 4, pp. 305-313, Apr. 1994. (Pubitemid 24169641)
10. X. Navarro et al., "Stimulation and recording from regenerated peripheral nerves through polyimide sieve electrodes," J. Peripheral Nervous Syst., vol. 3, pp. 91-101, 1998. (Pubitemid 28185681)
11. T. Stieglitz et al., "Aflexible, light-weightmultichannel sieve electrode with integrated cables for interfacing regenerating peripheral nerves," Sensors Actuators a-Physical, vol. 60, pp. 240-243, May 1997. (Pubitemid 127389261)
12. X. Navarro et al., "A critical review of interfaces with the peripheral nervous system for the control of neuroprostheses and hybrid bionic systems," J. Peripheral Nervous Syst., vol. 10, pp. 229-258, Sep. 2005. (Pubitemid 41580030)
13. K. Garde et al., "Early interfaced neural activity from chronic amputated nerves," Front Neuroeng., vol. 2, pp. 5-5, May 2009.
14. S. H. Cho et al., "Regeneration microelectrode array for peripheral- nerve recording and stimulations," IEEE Sensors J., vol. 8, pp. 1830-1836, Nov.-Dec. 2008.
15. J. J. FitzGerald et al., "Recording with microchannel electrodes in a noisy environment," in Proc. IEEE Eng. Med. Biol. Soc. Conf., 2008, vol. 2008, pp. 34-37.
16. D. J. Edell and R. R. Riso, "Long term bi-directional axon-electronic communication system," U.S. Patent 11 629 257, Jun. 15, 2005.
17. D. Lewitus et al., "Designing tyrosine-derived polycarbonate polymers for biodegradable regenerative type neural interface capable of neural recording," IEEE Trans. Neural Syst. Rehabil. Eng., vol. 19, no. 2, pp. 204-212, Apr. 2011.
18. A. Srinivasan et al., "Regenerative microchannel electrode array for peripheral nerve interfacing," in Proc. 5th Int. IEEE Eng. Med. Biol. Soc. Conf. Neural Eng., Cancun, Mexico, 2011, pp. 253-256.
19. J. L. Seifert et al., "Normal molecular repair mechanisms in regenerative peripheral nerve interfaces allow recording of early spike activity despite immature myelination," IEEE Trans. Neural Syst. Rehabil. Eng., vol. 20, no. 2, pp. 220-227, Mar. 2012.
20. C. Miller et al., "Micropatterned Schwann cell-seeded biodegradable polymer substrates significantly enhance neurite alignment and outgrowth," Tissue Eng., vol. 717, pp. 705-715, Dec. 2001. (Pubitemid 34042303)
21. D. M. Thompson andH.M. Buettner, "Neurite outgrowth is directed by Schwann cell alignment in the absence of other guidance cues," Ann. Biomed. Eng., vol. 34, pp. 669-676, Apr. 2006.
22. M. E. Manwaring et al., "Contact guidance induced organization of extracellular matrix," Biomaterials, vol. 25, pp. 3631-3638, Aug. 2004. (Pubitemid 38327051)
23. A. Curtis and C. Wilkinson, "Topographical control of cells," Biomaterials, vol. 18, pp. 1573-1583, Dec. 1997. (Pubitemid 28185057)
24. K. Matsumoto et al., "Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid (PGA)-collagen tube filled with laminin-coated collagen fibers: A histological and electrophysiological evaluation of regenerated nerves," Brain Res., vol. 868, pp. 315-328, Jun. 2000. (Pubitemid 30347528)
25. G. Lundborg and M. Kanje, "Bioartificial nerve grafts - A prototype," Scand. J. Plastic Reconstructive Surg. Hand Surg., vol. 30, pp. 105-110, Jun. 1996.
26. T. T. Ngo et al., "Poly(L-lactide) microfilaments enhance peripheral nerve regeneration across extended nerve lesions," J. Neurosci. Res., vol. 72, pp. 227-238, Apr. 2003.
27. D. Ceballos et al., "Magnetically aligned collagen gel filling a collagen nerve guide improves peripheral nerve regeneration," Exp. Neurol., vol. 158, pp. 290-300, Aug. 1999. (Pubitemid 29382821)
28. Y. T. Kim et al., "The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps," Biomaterials, vol. 29, pp. 3117-3127, Jul. 2008.
29. I. P. Clements et al., "Thin-film enhanced nerve guidance channels for peripheral nerve repair," Biomaterials, vol. 30, pp. 3834-3846, Aug. 2009.
30. V. J. Mukhatyar et al., "Role of fibronectin in topographical guidance of neurite extension on electrospun fibers," Biomaterials, vol. 32, pp. 3958-3968, Jun. 2011.
31. C. B. Jenq and R. E. Coggeshall, "Regeneration of transected rat sciatic- nerves after using isolated nerve fragments as distal inserts in silicone tubes," Exp. Neurol., vol. 91, pp. 154-162, Jan. 1986. (Pubitemid 16146195)
32. L. R. Williams et al., "Competence of nerve-tissue as distal insert promoting nerve regeneration in a silicone chamber," Brain Res., vol. 293, pp. 201-211, Feb. 1984. (Pubitemid 14180990)
33. S. Y. Fu and T. Gordon, "The cellular and molecular basis of peripheral nerve regeneration," Molecular Neurobiol., vol. 14, pp. 67-116, Feb. -Apr. 1997. (Pubitemid 127720197)
34. S. P. Frostick et al., "Schwann cells, neurotrophic factors, and peripheral nerve regeneration," Microsurgery, vol. 18, pp. 397-405, 1998. (Pubitemid 29014397)
35. C. E. Schmidt et al., "Stimulation of neurite outgrowth using an electrically conducting polymer," Proc. Nat. Acad. Sci. USA, vol. 94, pp. 8948-8953, Aug. 1997. (Pubitemid 27357762)
36. A. A. Al-Majed et al., "Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration," J. Neurosci., vol. 20, pp. 2602-2608, Apr. 2000. (Pubitemid 30220347)
37. A. W. English et al., "Electrical stimulation promotes peripheral axon regeneration by enhanced neuronal neurotrophin signaling," Develop. Neurobiol., vol. 67, pp. 158-172, Feb. 2007.
38. I. P. Clements et al., "A regenerative electrode scaffold for peripheral nerve interfacing," in Proc. 3rd Int. Conf. IEEE Eng. Med. Biol. Soc. Conf. Neural Eng., Kohala Coast, HI, 2007, pp. 390-393. (Pubitemid 47432241)
39. L. Wallman et al., "The geometric design of micromachined silicon sieve electrodes influences functional nerve regeneration," Biomaterials, vol. 22, pp. 1187-1193, May 2001. (Pubitemid 32229943)
40. N. Lago et al., "Long term assessment of axonal regeneration through polyimide regenerative electrodes to interface the peripheral nerve," Biomaterials, vol. 26, pp. 2021-2031, May 2005. (Pubitemid 39575344)
41. P. Negredo et al., "Differential growth of axons from sensory and motor neurons through a regenerative electrode: A stereological, retrograde tracer, and functional study in the rat," Neuroscience, vol. 128, pp. 605-615, 2004. (Pubitemid 39277430)
42. D. J. Tyler and D. M. Durand, "Functionally selective peripheral nerve stimulation with a flat interface nerve electrode," IEEE Trans. Neural Syst. Rehabil. Eng., vol. 10, no. 4, pp. 294-303, Dec. 2002. (Pubitemid 36210939)
43. K. V. Slavin, "Peripheral nerve stimulation for neuropathic pain," Neurotherapeutics, vol. 5, pp. 100-106, Jan. 2008. (Pubitemid 350299309)
44. W. Jensen et al., "Development of an implantable transverse intrafascicular multichannel electrode (TIME) system for relieving phantom limb pain," in Annu. Int. Conf. IEEE EMBS, 2010, pp. 6214-6217.
45. B. S. Nashold et al., "Long-termpain control by direct peripheral-nerve stimulation," J. Bone Joint Surg., vol. 64, pp. 1-10, 1982.
46. P. D. Wall and W. H. Sweet, "Temporary abolition of pain in man," Science, vol. 155, pp. 108-109, 1967.
47. J. W. Boggs et al., "Spinal micturition reflex mediated by afferents in the deep perineal nerve," J. Neurophysiol., vol. 93, pp. 2688-2697, May 2005. (Pubitemid 40570849)
48. C. Veraart et al., "Selective control of muscle activation with a multipolar nerve cuff electrode," IEEE Trans. Biomed. Eng., vol. 40, no. 7, pp. 640-653, Jul. 1993. (Pubitemid 24065539)
49. L. R. Williams et al., "Spatial-temporal progress of peripheral-nerve regeneration within a silicone chamber - Parameters for a bioassay," J. Comparative Neurol., vol. 218, pp. 460-470, 1983. (Pubitemid 13039242)
50. L. R. Williams and S. Varon, "Modification of fibrin matrix formation insitu enhances nerve regeneration in silicone chambers," J. Comparative Neurol., vol. 231, pp. 209-220, 1985. (Pubitemid 15159972)
51. Q. Zhao et al., "Repair of the transected rat sciatic-nerve - Matrix formation within implanted silicone tubes," Restorative Neurol. Neurosci., vol. 5, pp. 197-204, May 1993. (Pubitemid 23162975)
52. H. M. Liu, "The role of extracellular-matrix in peripheral-nerve regeneration - A wound chamber study," Acta Neuropathol., vol. 83, pp. 469-474, Apr. 1992.
53. K. W. Horch and S. J. W. Lisney, "On the number and nature of regenerating myelinated axons after lesions of cutaneous nerves in the cat," J. Physiol. London, 313, pp. 275-286, Apr. 1981. (Pubitemid 11125575)
54. J. A. Hoffer et al., "Differential atrophy of sensory and motor fibers following section of cat peripheral-nerves," Brain Res., vol. 178, pp. 347-361, Dec. 1979. (Pubitemid 10194659)
55. T. E. Milner and R. B. Stein, "The effects of axotomy on the conduction of action-potentials in peripheral sensory and motor-nerve fibers," J. Neurol. Neurosurg. Psychiat., vol. 44, pp. 485-496, 1981. (Pubitemid 11046552)
56. N. Lago and X. Navarro, "Evaluation of the long-term regenerative potential in an experimental nerve amputee model," J. Peripheral Nervous Syst., vol. 12, pp. 108-120, Jun. 2007. (Pubitemid 46906333)
57. J. Carlson et al., "Axonal atrophy from permanent peripheral axotomy in adult cat," J. Neuropathol. Exp. Neurol., vol. 38, pp. 579-585, 1979. (Pubitemid 10163499)
58. G. E. Loeb and R. A. Peck, "Cuff electrodes for chronic stimulation and recording of peripheral nerve activity," J. Neurosci. Methods, vol. 64, pp. 95-103, Jan. 1996. (Pubitemid 26069896)
59. L. A. Geddes and R. Roeder, "Criteria for the selection of materials for implanted electrodes," Ann. Biomed. Eng., vol. 31, pp. 879-890, Jul.-Aug. 2003.
60. E. W. Keefer et al., "Carbon nanotube coating improves neuronal recordings," Nat. Nanotechnol., vol. 3, pp. 434-439, Jul. 2008. (Pubitemid 351948248)
61. A. F. Huxley and R. Stampfli, "Evidence for saltatory conduction in peripheral myelinated nerve fibres," J. Physiol., vol. 108, pp. 315-339, May 1949.
62. L. Guo et al., "A conformable microelectrode array (cMEA) with integrated electronics for peripheral nerve interfacing," in IEEE Biomed. Circuits Syst. Conf., Paphos, Cyprus, 2010, pp. 194 -197.
63. S. Micera et al., "Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfaces," J. Neuroeng. Rehabil., vol. 8, pp. 53-53, 2011.
64. E. S. Boyden et al., "Millisecond-timescale, genetically targeted optical control of neural activity," Nature Neurosci., vol. 8, pp. 1263-1268, Sep. 2005. (Pubitemid 43348147)
65. M. E. Llewellyn et al., "Orderly recruitment of motor units under optical control in vivo," Nature Med., vol. 16, pp. 1161-1165, Oct. 2010.
66. C.Miller et al., "Synergistic effects of physical and chemical guidance cues on neurite alignment and outgrowth on biodegradable polymer substrates," Tissue Eng., vol. 8, pp. 367-378, Jun. 2002. (Pubitemid 34747795)
67. X. J. Yu et al., "A laminin and nerve growth factor-laden three-dimensional scaffold for enhanced neurite extension," Tissue Eng., vol. 5, pp. 291-304, Aug. 1999.