-
1
-
-
78951484731
-
Managing suicide risk in patients with schizophrenia
-
21254789 10.2165/11586450-000000000-00000 1:CAS:528:DC%2BC3MXjsFOjt78%3D
-
Kasckow J, Felmet K, Zisook S (2011) Managing suicide risk in patients with schizophrenia. CNS Drugs 25:129-143
-
(2011)
CNS Drugs
, vol.25
, pp. 129-143
-
-
Kasckow, J.1
Felmet, K.2
Zisook, S.3
-
2
-
-
3042576182
-
Poor antipsychotic adherence among patients with schizophrenia: Medication and patient factors
-
15279044 10.1093/oxfordjournals.schbul.a007076
-
Valenstein M, Blow FC, Copeland LA et al (2004) Poor antipsychotic adherence among patients with schizophrenia: medication and patient factors. Schizophr Bull 30:255-264
-
(2004)
Schizophr Bull
, vol.30
, pp. 255-264
-
-
Valenstein, M.1
Blow, F.C.2
Copeland, L.A.3
-
3
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
19571811 1:CAS:528:DC%2BD1MXotVSgtLg%3D
-
Purcell SM, Wray NR, Stone JL et al (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460:748-752
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
-
4
-
-
38949090435
-
Iloperidone: A new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market?
-
18095919 10.1517/13543784.17.1.61 1:CAS:528:DC%2BD1cXhtFSmsw%3D%3D
-
Albers LJ, Musenga A, Raggi MA (2008) Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs 17:61-75
-
(2008)
Expert Opin Investig Drugs
, vol.17
, pp. 61-75
-
-
Albers, L.J.1
Musenga, A.2
Raggi, M.A.3
-
5
-
-
38749140981
-
Functional neuroimaging in schizophrenia: Diagnosis and drug discovery
-
18187211 10.1016/j.tips.2007.11.005 1:CAS:528:DC%2BD1cXhslOjsbw%3D
-
McGuire P, Howes OD, Stone J, Fusar-Poli P (2008) Functional neuroimaging in schizophrenia: diagnosis and drug discovery. Trends Pharmacol Sci 29:91-98
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 91-98
-
-
McGuire, P.1
Howes, O.D.2
Stone, J.3
Fusar-Poli, P.4
-
6
-
-
84880436430
-
-
Accessed on Feb 18, 2013
-
Potkin SG. PET Findings with Iloperidone. 2008. Available from: http://www.nccmedical.com/images/portfolio%20samples/USPMHC-Poster-2011.pdf Accessed on Feb 18, 2013
-
(2008)
PET Findings with Iloperidone
-
-
Potkin, S.G.1
-
7
-
-
79955980924
-
Iloperidone: A new drug for the treatment of schizophrenia
-
21289324 10.2146/ajhp100079 1:CAS:528:DC%2BC38XotFKiu7s%3D
-
Arif SA, Mitchell MM (2011) Iloperidone: a new drug for the treatment of schizophrenia. Am J Health Syst Pharm 68:301-308
-
(2011)
Am J Health Syst Pharm
, vol.68
, pp. 301-308
-
-
Arif, S.A.1
Mitchell, M.M.2
-
8
-
-
77954806555
-
Iloperidone for schizophrenia
-
20586713 10.1517/14656566.2010.502889 1:CAS:528:DC%2BC3cXptVantLg%3D
-
Rado J, Janicak PG (2010) Iloperidone for schizophrenia. Expert Opin Pharmacother 11:2087-2093
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 2087-2093
-
-
Rado, J.1
Janicak, P.G.2
-
9
-
-
0036199878
-
Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone
-
11999907 10.1016/S0278-5846(01)00307-4 1:CAS:528:DC%2BD38XjtFCgtr0%3D
-
Subramanian N, Kalkman HO (2002) Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone. Prog Neuropsychopharmacol Biol Psychiatry 26:553-560
-
(2002)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.26
, pp. 553-560
-
-
Subramanian, N.1
Kalkman, H.O.2
-
10
-
-
80053383810
-
AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: Update
-
10.1055/s-0031-1286287
-
Hiemke C, Baumann P, Bergemann N et al (2011) AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update. Pharmacopsychiatry 44:195-235
-
(2011)
Pharmacopsychiatry
, vol.44
, pp. 195-235
-
-
Hiemke, C.1
Baumann, P.2
Bergemann, N.3
-
11
-
-
40849089245
-
Efficacy of iloperidone in the treatment of schizophrenia: Initial phase 3 studies
-
18334911 10.1097/JCP.0b013e3181692787 1:CAS:528:DC%2BD1cXjtVKgtL0%3D
-
Potkin SG, Litman RE, Torres R, Wolfgang CD (2008) Efficacy of iloperidone in the treatment of schizophrenia: initial phase 3 studies. J Clin Psychopharmacol 28:S4-S11
-
(2008)
J Clin Psychopharmacol
, vol.28
-
-
Potkin, S.G.1
Litman, R.E.2
Torres, R.3
Wolfgang, C.D.4
-
12
-
-
40849111788
-
Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia
-
18334909 10.1097/JCP.0b013e318169d4ce 1:CAS:528:DC%2BD1cXjtVKgtLY%3D
-
Cutler AJ, Kalali AH, Weiden PJ, Hamilton J, Wolfgang CD (2008) Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia. J Clin Psychopharmacol 28:S20-S28
-
(2008)
J Clin Psychopharmacol
, vol.28
-
-
Cutler, A.J.1
Kalali, A.H.2
Weiden, P.J.3
Hamilton, J.4
Wolfgang, C.D.5
-
13
-
-
84856324879
-
Efficacy of iloperidone in the short-term treatment of schizophrenia: A post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials
-
22161738 10.1002/hup.1254 1:CAS:528:DC%2BC38XjtVKjtrs%3D
-
Citrome L, Meng X, Hochfeld M, Stahl SM (2012) Efficacy of iloperidone in the short-term treatment of schizophrenia: a post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials. Hum Psychopharmacol 27:24-32
-
(2012)
Hum Psychopharmacol
, vol.27
, pp. 24-32
-
-
Citrome, L.1
Meng, X.2
Hochfeld, M.3
Stahl, S.M.4
-
14
-
-
40849114977
-
Long-term efficacy and safety of iloperidone: Results from 3 clinical trials for the treatment of schizophrenia
-
18334910 10.1097/JCP.0b013e318169cca7 1:CAS:528:DC%2BD1cXjtVKgtb4%3D
-
Kane JM, Lauriello J, Laska E, Di Marino M, Wolfgang CD (2008) Long-term efficacy and safety of iloperidone: results from 3 clinical trials for the treatment of schizophrenia. J Clin Psychopharmacol 28:S29-S35
-
(2008)
J Clin Psychopharmacol
, vol.28
-
-
Kane, J.M.1
Lauriello, J.2
Laska, E.3
Di Marino, M.4
Wolfgang, C.D.5
-
15
-
-
40849102838
-
Safety profile of iloperidone: A pooled analysis of 6-week acute-phase pivotal trials
-
18334908 10.1097/JCP.0b013e3181694f5a 1:CAS:528:DC%2BD1cXjtVKgtLg%3D
-
Weiden PJ, Cutler AJ, Polymeropoulos MH, Wolfgang CD (2008) Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials. J Clin Psychopharmacol 28:S12-S19
-
(2008)
J Clin Psychopharmacol
, vol.28
-
-
Weiden, P.J.1
Cutler, A.J.2
Polymeropoulos, M.H.3
Wolfgang, C.D.4
-
16
-
-
84860460685
-
Iloperidone fanapt(R), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration
-
doi: 10.1016/j.phrs.2012.03.008
-
Vigneault P, Pilote S, Patoine D, Simard C, Drolet B (2012) Iloperidone fanapt(R), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration. Pharmacol Res. doi: 10.1016/j.phrs.2012.03.008
-
(2012)
Pharmacol Res.
-
-
Vigneault, P.1
Pilote, S.2
Patoine, D.3
Simard, C.4
Drolet, B.5
-
17
-
-
67651174493
-
Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study
-
18521090 10.1038/mp.2008.56 1:CAS:528:DC%2BD1MXptVCjtb0%3D
-
Lavedan C, Licamele L, Volpi S et al (2009) Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study. Mol Psychiatry 14:804-819
-
(2009)
Mol Psychiatry
, vol.14
, pp. 804-819
-
-
Lavedan, C.1
Licamele, L.2
Volpi, S.3
-
18
-
-
67649216860
-
Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia
-
19573479 10.4088/JCP.08m04391 1:CAS:528:DC%2BD1MXhsFentbnL
-
Volpi S, Potkin SG, Malhotra AK, Licamele L, Lavedan C (2009) Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia. J Clin Psychiatry 70:801-809
-
(2009)
J Clin Psychiatry
, vol.70
, pp. 801-809
-
-
Volpi, S.1
Potkin, S.G.2
Malhotra, A.K.3
Licamele, L.4
Lavedan, C.5
-
19
-
-
70350574270
-
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
-
18521091 10.1038/mp.2008.52 1:CAS:528:DC%2BD1MXhtlSgs7vK
-
Volpi S, Heaton C, Mack K et al (2009) Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Mol Psychiatry 14:1024-1031
-
(2009)
Mol Psychiatry
, vol.14
, pp. 1024-1031
-
-
Volpi, S.1
Heaton, C.2
MacK, K.3
-
20
-
-
77954787424
-
Evaluation of the clinical efficacy of asenapine in schizophrenia
-
20642375 10.1517/14656566.2010.506188 1:CAS:528:DC%2BC3cXptVant7c%3D
-
Minassian A, Young JW (2010) Evaluation of the clinical efficacy of asenapine in schizophrenia. Expert Opin Pharmacother 11:2107-2115
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 2107-2115
-
-
Minassian, A.1
Young, J.W.2
-
21
-
-
58649100010
-
Asenapine: A novel psychopharmacologic agent with a unique human receptor signature
-
18308814 10.1177/0269881107082944 1:CAS:528:DC%2BD1MXisVClu7Y%3D
-
Shahid M, Walker GB, Zorn SH, Wong EH (2009) Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol 23:65-73
-
(2009)
J Psychopharmacol
, vol.23
, pp. 65-73
-
-
Shahid, M.1
Walker, G.B.2
Zorn, S.H.3
Wong, E.H.4
-
22
-
-
70449702359
-
Asenapine monotherapy in the acute treatment of both schizophrenia and bipolar i disorder
-
19851515 1:CAS:528:DC%2BD1MXht1aitb3N
-
Bishara D, Taylor D (2009) Asenapine monotherapy in the acute treatment of both schizophrenia and bipolar I disorder. Neuropsychiatr Dis Treat 5:483-490
-
(2009)
Neuropsychiatr Dis Treat
, vol.5
, pp. 483-490
-
-
Bishara, D.1
Taylor, D.2
-
23
-
-
84880407418
-
-
FDA Psychopharmacologic Drugs Advisory Committee Meeting Accessed on Feb 18, 2013
-
FDA Psychopharmacologic Drugs Advisory Committee Meeting (2009) Available from http://www.fda.gov/downloads/AdvisoryCommittees/ CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/ UCM173876.pdf Accessed on Feb 18, 2013
-
(2009)
-
-
-
24
-
-
80053629745
-
Role of sublingual asenapine in treatment of schizophrenia
-
21655346 10.2147/NDT.S16077 1:CAS:528:DC%2BC3MXntVKkt7Y%3D
-
Citrome L (2011) Role of sublingual asenapine in treatment of schizophrenia. Neuropsychiatr Dis Treat 7:325-339
-
(2011)
Neuropsychiatr Dis Treat
, vol.7
, pp. 325-339
-
-
Citrome, L.1
-
25
-
-
68949207145
-
Asenapine
-
19689168 10.2165/11200860-000000000-00000 1:CAS:528:DC%2BD1MXht1KiurjF
-
Weber J, McCormack PL (2009) Asenapine. CNS Drugs 23:781-792
-
(2009)
CNS Drugs
, vol.23
, pp. 781-792
-
-
Weber, J.1
McCormack, P.L.2
-
26
-
-
77952154800
-
Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia
-
20520283 10.1097/JCP.0b013e3181d35d6b 1:CAS:528:DC%2BC3cXkvVOqt70%3D
-
Kane JM, Cohen M, Zhao J, Alphs L, Panagides J (2010) Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia. J Clin Psychopharmacol 30:106-115
-
(2010)
J Clin Psychopharmacol
, vol.30
, pp. 106-115
-
-
Kane, J.M.1
Cohen, M.2
Zhao, J.3
Alphs, L.4
Panagides, J.5
-
27
-
-
80053635565
-
Eficacy of asenapine for schizophrenia: Comparison with placebo and comparative efficacy of all atypical antipsychotics using all available head-to-head randomized trials using meta-analytical techniques
-
10.1038/npp.2009.109
-
Szegedi A, Verweij P, Van Dujinhoven W (2010) Eficacy of asenapine for schizophrenia: comparison with placebo and comparative efficacy of all atypical antipsychotics using all available head-to-head randomized trials using meta-analytical techniques. Neuropsychopharmacology 35:S105
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 105
-
-
Szegedi, A.1
Verweij, P.2
Van Dujinhoven, W.3
-
28
-
-
77953753014
-
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity
-
20404009 10.1124/jpet.110.167346 1:CAS:528:DC%2BC3cXos1KltLo%3D
-
Ishibashi T, Horisawa T, Tokuda K et al (2010) Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther 334:171-181
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 171-181
-
-
Ishibashi, T.1
Horisawa, T.2
Tokuda, K.3
-
29
-
-
83255186320
-
Lurasidone: A new treatment option for schizophrenia
-
1:STN:280:DC%2BC38%2FlsVCmtw%3D%3D
-
Owen RT (2011) Lurasidone: a new treatment option for schizophrenia. Drugs Today (Barc) 47:807-816
-
(2011)
Drugs Today (Barc)
, vol.47
, pp. 807-816
-
-
Owen, R.T.1
-
30
-
-
84555200240
-
Clinical potential of lurasidone in the management of schizophrenia
-
21753886 10.2147/TCRM.S12701 1:CAS:528:DC%2BC3MXpvVGjtb4%3D
-
Samalin L, Garnier M, Llorca PM (2011) Clinical potential of lurasidone in the management of schizophrenia. Ther Clin Risk Manag 7:239-250
-
(2011)
Ther Clin Risk Manag
, vol.7
, pp. 239-250
-
-
Samalin, L.1
Garnier, M.2
Llorca, P.M.3
-
31
-
-
84872331092
-
Evaluation of dopamine D(2)/D(3) and serotonin 5-HT(2)a receptor occupancy for a novel antipsychotic, lurasidone, in conscious common marmosets using small-animal positron emission tomography
-
10.1007/s00213-012-2815-9 1:CAS:528:DC%2BC38XhtFCrt7nP
-
Nakazawa S, Yokoyama C, Nishimura N et al (2013) Evaluation of dopamine D(2)/D(3) and serotonin 5-HT(2)a receptor occupancy for a novel antipsychotic, lurasidone, in conscious common marmosets using small-animal positron emission tomography. Psychopharmacology (Berl) 225:329-339
-
(2013)
Psychopharmacology (Berl)
, vol.225
, pp. 329-339
-
-
Nakazawa, S.1
Yokoyama, C.2
Nishimura, N.3
-
32
-
-
73849100354
-
Lurasidone: A new drug in development for schizophrenia
-
19780705 10.1517/13543780903286388 1:CAS:528:DC%2BD1MXhtlKrtrjL
-
Meyer JM, Loebel AD, Schweizer E (2009) Lurasidone: a new drug in development for schizophrenia. Expert Opin Investig Drugs 18:1715-1726
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1715-1726
-
-
Meyer, J.M.1
Loebel, A.D.2
Schweizer, E.3
-
33
-
-
78650664657
-
Lurasidone for schizophrenia: A brief review of a new second-generation antipsychotic
-
21177242 10.3371/CSRP.4.4.5
-
Citrome L (2011) Lurasidone for schizophrenia: a brief review of a new second-generation antipsychotic. Clin Schizophr Relat Psychoses 4:251-257
-
(2011)
Clin Schizophr Relat Psychoses
, vol.4
, pp. 251-257
-
-
Citrome, L.1
-
34
-
-
78650662417
-
Lurasidone for schizophrenia: A review of the efficacy and safety profile for this newly approved second-generation antipsychotic
-
21129135 10.1111/j.1742-1241.2010.02587.x 1:CAS:528:DC%2BC3MXjt1WqtLg%3D
-
Citrome L (2011) Lurasidone for schizophrenia: a review of the efficacy and safety profile for this newly approved second-generation antipsychotic. Int J Clin Pract 65:189-210
-
(2011)
Int J Clin Pract
, vol.65
, pp. 189-210
-
-
Citrome, L.1
-
35
-
-
79952316290
-
Performance and interview-based assessments of cognitive change in a randomized, double-blind comparison of lurasidone vs. Ziprasidone
-
21277745 10.1016/j.schres.2011.01.004
-
Harvey PD, Ogasa M, Cucchiaro J, Loebel A, Keefe RS (2011) Performance and interview-based assessments of cognitive change in a randomized, double-blind comparison of lurasidone vs. Ziprasidone. Schizophr Res 127:188-194
-
(2011)
Schizophr Res
, vol.127
, pp. 188-194
-
-
Harvey, P.D.1
Ogasa, M.2
Cucchiaro, J.3
Loebel, A.4
Keefe, R.S.5
-
36
-
-
78751548202
-
Effect of lurasidone on depressive symptoms in patients with schizophrenia
-
Ogasa MLACJ (2009) Effect of lurasidone on depressive symptoms in patients with schizophrenia. Schizophr Bull 35:344-345
-
(2009)
Schizophr Bull
, vol.35
, pp. 344-345
-
-
Ogasa, M.1
-
37
-
-
84859268864
-
Long-term safety and tolerability of lurasidone in schizophrenia: A 12-month, double-blind, active-controlled study
-
22395527 10.1097/YIC.0b013e32835281ef
-
Citrome L, Cucchiaro J, Sarma K et al (2012) Long-term safety and tolerability of lurasidone in schizophrenia: a 12-month, double-blind, active-controlled study. Int Clin Psychopharmacol 27:165-176
-
(2012)
Int Clin Psychopharmacol
, vol.27
, pp. 165-176
-
-
Citrome, L.1
Cucchiaro, J.2
Sarma, K.3
-
38
-
-
84880400034
-
-
Lurasidone (Latuda) for schizophrenia
-
Lurasidone (Latuda) for schizophrenia (2011) Med Lett Drugs Ther 53:13-14
-
(2011)
Med Lett Drugs Ther
, vol.53
, pp. 13-14
-
-
-
39
-
-
79955116386
-
Iloperidone, asenapine, and lurasidone: A brief overview of 3 new second-generation antipsychotics
-
21474903 10.3810/pgm.2011.03.2273
-
Citrome L (2011) Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics. Postgrad Med 123:153-162
-
(2011)
Postgrad Med
, vol.123
, pp. 153-162
-
-
Citrome, L.1
-
40
-
-
80052593267
-
Lurasidone HCl (latuda), an oral, once-daily atypical antipsychotic agent for the treatment of patients with schizophrenia
-
21935296
-
Cruz MP (2011) Lurasidone HCl (latuda), an oral, once-daily atypical antipsychotic agent for the treatment of patients with schizophrenia. P T 36:489-492
-
(2011)
P T
, vol.36
, pp. 489-492
-
-
Cruz, M.P.1
-
41
-
-
67649222011
-
Lurasidone in the treatment of acute schizophrenia: A double-blind, placebo-controlled trial
-
19497249 10.4088/JCP.08m04905 1:CAS:528:DC%2BD1MXhsFentbnF
-
Nakamura M, Ogasa M, Guarino J et al (2009) Lurasidone in the treatment of acute schizophrenia: a double-blind, placebo-controlled trial. J Clin Psychiatry 70:829-836
-
(2009)
J Clin Psychiatry
, vol.70
, pp. 829-836
-
-
Nakamura, M.1
Ogasa, M.2
Guarino, J.3
-
42
-
-
80054080823
-
Double-blind comparison of the safety and efficacy of lurasidone and ziprasidone in clinically stable outpatients with schizophrenia or schizoaffective disorder
-
21889878 10.1016/j.schres.2011.04.008
-
Potkin SG, Ogasa M, Cucchiaro J, Loebel A (2011) Double-blind comparison of the safety and efficacy of lurasidone and ziprasidone in clinically stable outpatients with schizophrenia or schizoaffective disorder. Schizophr Res 132:101-107
-
(2011)
Schizophr Res
, vol.132
, pp. 101-107
-
-
Potkin, S.G.1
Ogasa, M.2
Cucchiaro, J.3
Loebel, A.4
-
43
-
-
77649268156
-
Blonanserin: A review of its use in the management of schizophrenia
-
20030420 10.2165/11202620-000000000-00000 1:CAS:528:DC%2BC3cXivVamsLg%3D
-
Deeks ED, Keating GM (2010) Blonanserin: a review of its use in the management of schizophrenia. CNS Drugs 24:65-84
-
(2010)
CNS Drugs
, vol.24
, pp. 65-84
-
-
Deeks, E.D.1
Keating, G.M.2
-
44
-
-
77953716951
-
Atypical antipsychotic properties of blonanserin, a novel dopamine D2 and 5-HT2A antagonist
-
20460137 10.1016/j.pbb.2010.04.027 1:CAS:528:DC%2BC3cXntlWqsL0%3D
-
Ohno Y, Okano M, Imaki J, Tatara A, Okumura T, Shimizu S (2010) Atypical antipsychotic properties of blonanserin, a novel dopamine D2 and 5-HT2A antagonist. Pharmacol Biochem Behav 96:175-180
-
(2010)
Pharmacol Biochem Behav
, vol.96
, pp. 175-180
-
-
Ohno, Y.1
Okano, M.2
Imaki, J.3
Tatara, A.4
Okumura, T.5
Shimizu, S.6
-
45
-
-
84874935839
-
Striatal and Extrastriatal Dopamine D2 Receptor Occupancy by a Novel Antipsychotic, Blonanserin: A PET Study with [11C]Raclopride and [11C]FLB 457 in Schizophrenia
-
Tateno A, Arakawa R, Okumura, M et al (2013) Striatal and Extrastriatal Dopamine D2 Receptor Occupancy by a Novel Antipsychotic, Blonanserin: A PET Study With [11C]Raclopride and [11C]FLB 457 in Schizophrenia. J Clin Psychopharmacol
-
(2013)
J Clin Psychopharmacol
-
-
Tateno, A.1
Arakawa, R.2
Okumura, M.3
-
46
-
-
77956186378
-
Effect of dose timing in relation to food intake on systemic exposure to blonanserin
-
20490472 10.1007/s00228-010-0834-1 1:CAS:528:DC%2BC3cXhtVahsbjP
-
Saruwatari J, Yasui-Furukori N, Inoue Y, Kaneko S (2010) Effect of dose timing in relation to food intake on systemic exposure to blonanserin. Eur J Clin Pharmacol 66:899-902
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 899-902
-
-
Saruwatari, J.1
Yasui-Furukori, N.2
Inoue, Y.3
Kaneko, S.4
-
47
-
-
67649390905
-
The efficacy and safety of blonanserin compared with haloperidol in acute-phase schizophrenia: A randomized, double-blind, placebo-controlled, multicentre study
-
19552488 10.2165/00023210-200923070-00006 1:CAS:528:DC%2BD1MXpvFeitbw%3D
-
Garcia E, Robert M, Peris F, Nakamura H, Sato N, Terazawa Y (2009) The efficacy and safety of blonanserin compared with haloperidol in acute-phase schizophrenia: a randomized, double-blind, placebo-controlled, multicentre study. CNS Drugs 23:615-625
-
(2009)
CNS Drugs
, vol.23
, pp. 615-625
-
-
Garcia, E.1
Robert, M.2
Peris, F.3
Nakamura, H.4
Sato, N.5
Terazawa, Y.6
-
48
-
-
77955141217
-
Efficacy and tolerability of Blonanserin in the patients with schizophrenia: A randomized, double-blind, risperidone-compared trial
-
20661022 10.1097/WNF.0b013e3181dcda50 1:CAS:528:DC%2BC3cXpsVCgsb4%3D
-
Yang J, Bahk WM, Cho HS et al (2010) Efficacy and tolerability of Blonanserin in the patients with schizophrenia: a randomized, double-blind, risperidone-compared trial. Clin Neuropharmacol 33:169-175
-
(2010)
Clin Neuropharmacol
, vol.33
, pp. 169-175
-
-
Yang, J.1
Bahk, W.M.2
Cho, H.S.3
-
49
-
-
84856347531
-
Effect of blonanserin on cognitive function in antipsychotic-naive first-episode schizophrenia
-
22278973 10.1002/hup.1276 1:CAS:528:DC%2BC38XjtVKjtLo%3D
-
Tenjin T, Miyamoto S, Miyake N et al (2012) Effect of blonanserin on cognitive function in antipsychotic-naive first-episode schizophrenia. Hum Psychopharmacol 27:90-100
-
(2012)
Hum Psychopharmacol
, vol.27
, pp. 90-100
-
-
Tenjin, T.1
Miyamoto, S.2
Miyake, N.3
-
50
-
-
79959627746
-
Blonanserin in the treatment of delirium
-
21569175 10.1111/j.1440-1819.2011.02213.x 1:CAS:528:DC%2BC3MXhtVCqt7zN
-
Kato K, Yamada K, Maehara M et al (2011) Blonanserin in the treatment of delirium. Psychiatry Clin Neurosci 65:389-391
-
(2011)
Psychiatry Clin Neurosci
, vol.65
, pp. 389-391
-
-
Kato, K.1
Yamada, K.2
Maehara, M.3
-
51
-
-
84880433637
-
-
Efficiency Study to Investigate Blonanserin in Treatment of Schizophrenia When Compared With Risperidone. Clinical Trials.Gov [updated 19 January 2012, cited 2012 Apr 14]
-
Efficiency Study to Investigate Blonanserin in Treatment of Schizophrenia When Compared With Risperidone. Clinical Trials.Gov [updated 19 January 2012, cited 2012 Apr 14]. Available from [ http://clinicaltrials.gov/ct2/show/ NCT01516424?term=blonanserin&rank=1 ]
-
-
-
-
52
-
-
77949701274
-
Cariprazine (RGH-188), a dopamine D(3) receptor-preferring, D(3)/D(2) dopamine receptor antagonist-partial agonist antipsychotic candidate: In vitro and neurochemical profile
-
20093397 10.1124/jpet.109.160432 1:CAS:528:DC%2BC3cXkvFGktLs%3D
-
Kiss B, Horvath A, Nemethy Z et al (2010) Cariprazine (RGH-188), a dopamine D(3) receptor-preferring, D(3)/D(2) dopamine receptor antagonist-partial agonist antipsychotic candidate: in vitro and neurochemical profile. J Pharmacol Exp Ther 333:328-340
-
(2010)
J Pharmacol Exp Ther
, vol.333
, pp. 328-340
-
-
Kiss, B.1
Horvath, A.2
Nemethy, Z.3
-
53
-
-
82955233447
-
1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography
-
10.1007/s00213-011-2343-z 1:CAS:528:DC%2BC3MXmslSru7w%3D
-
1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl) 218:579-587
-
(2011)
Psychopharmacology (Berl)
, vol.218
, pp. 579-587
-
-
Seneca, N.1
Finnema, S.J.2
Laszlovszky, I.3
-
54
-
-
77954111992
-
Dopamine D2 and D3 receptor occupancy of cariprazine in schizophrenic patients
-
Keator DB, Mukherjee J, Preda A (2009) Dopamine D2 and D3 receptor occupancy of cariprazine in schizophrenic patients. Schizophr Bull 35:154
-
(2009)
Schizophr Bull
, vol.35
, pp. 154
-
-
Keator, D.B.1
Mukherjee, J.2
Preda, A.3
-
55
-
-
34548771303
-
The selective dopamine D3 receptor antagonists, SB 277011-A and S 33084 block haloperidol-induced catalepsy in rats
-
17628535 10.1016/j.ejphar.2007.06.035 1:CAS:528:DC%2BD2sXhtVOlsbvI
-
Gyertyan I, Saghy K (2007) The selective dopamine D3 receptor antagonists, SB 277011-A and S 33084 block haloperidol-induced catalepsy in rats. Eur J Pharmacol 572:171-174
-
(2007)
Eur J Pharmacol
, vol.572
, pp. 171-174
-
-
Gyertyan, I.1
Saghy, K.2
-
56
-
-
84891638911
-
Cariprazine in schizophrenia: Clinical efficacy, tolerability, and place in therapy
-
Jan 28
-
Citrome L. Cariprazine in Schizophrenia: Clinical Efficacy, Tolerability, and Place in Therapy. Adv Ther 2013 Jan 28
-
(2013)
Adv Ther
-
-
Citrome, L.1
-
57
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
17767166 10.1038/nm1632 1:CAS:528:DC%2BD2sXhtVSgtrvF
-
Patil ST, Zhang L, Martenyi F et al (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 13:1102-1107
-
(2007)
Nat Med
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
-
58
-
-
79955594301
-
A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia
-
21508856 10.1097/JCP.0b013e318218dcd5 1:CAS:528:DC%2BC3MXltlyrtLg%3D
-
Kinon BJ, Zhang L, Millen BA et al (2011) A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia. J Clin Psychopharmacol 31:349-355
-
(2011)
J Clin Psychopharmacol
, vol.31
, pp. 349-355
-
-
Kinon, B.J.1
Zhang, L.2
Millen, B.A.3
-
59
-
-
57349174038
-
ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1, 2, 4]-oxadiazol-5-yl]-piperidin-1- yl}-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities
-
18753411 10.1124/jpet.108.136580 1:CAS:528:DC%2BD1cXhsVCjtLjN
-
Liu F, Grauer S, Kelley C et al (2008) ADX47273 [S-(4-fluoro-phenyl)-{3- [3-(4-fluoro-phenyl)-[1, 2, 4]-oxadiazol-5-yl]-piperidin-1- yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. J Pharmacol Exp Ther 327:827-839
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 827-839
-
-
Liu, F.1
Grauer, S.2
Kelley, C.3
-
60
-
-
79951656529
-
A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia
-
21145041 10.1016/j.biopsych.2010.09.052 1:CAS:528:DC%2BC3MXhvVyks7g%3D
-
Buchanan RW, Keefe RS, Lieberman JA et al (2011) A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia. Biol Psychiatry 69:442-449
-
(2011)
Biol Psychiatry
, vol.69
, pp. 442-449
-
-
Buchanan, R.W.1
Keefe, R.S.2
Lieberman, J.A.3
-
61
-
-
34447134086
-
Cognitive deficits in schizophrenia: Focus on neuronal nicotinic acetylcholine receptors and smoking
-
17554626 10.1007/s10571-007-9149-x 1:CAS:528:DC%2BD2sXnsVCjsLc%3D
-
Ochoa EL, Lasalde-Dominicci J (2007) Cognitive deficits in schizophrenia: focus on neuronal nicotinic acetylcholine receptors and smoking. Cell Mol Neurobiol 27:609-639
-
(2007)
Cell Mol Neurobiol
, vol.27
, pp. 609-639
-
-
Ochoa, E.L.1
Lasalde-Dominicci, J.2
-
62
-
-
68349141525
-
Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes
-
19615981 10.1016/j.bcp.2009.07.005 1:CAS:528:DC%2BD1MXhtVSmsb7I
-
Sydserff S, Sutton EJ, Song D et al (2009) Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochem Pharmacol 78:880-888
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 880-888
-
-
Sydserff, S.1
Sutton, E.J.2
Song, D.3
-
63
-
-
78649994788
-
Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors
-
20965497 10.1016/j.biopsych.2010.08.006 1:CAS:528:DC%2BC3cXhsFCrurjL
-
Castner SA, Smagin GN, Piser TM et al (2011) Immediate and sustained improvements in working memory after selective stimulation of alpha7 nicotinic acetylcholine receptors. Biol Psychiatry 69:12-18
-
(2011)
Biol Psychiatry
, vol.69
, pp. 12-18
-
-
Castner, S.A.1
Smagin, G.N.2
Piser, T.M.3
-
64
-
-
48949099564
-
Initial phase 2 trial of a nicotinic agonist in schizophrenia
-
18381905 10.1176/appi.ajp.2008.07071135
-
Freedman R, Olincy A, Buchanan RW et al (2008) Initial phase 2 trial of a nicotinic agonist in schizophrenia. Am J Psychiatry 165:1040-1047
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1040-1047
-
-
Freedman, R.1
Olincy, A.2
Buchanan, R.W.3
-
65
-
-
0035847383
-
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist
-
11212100 10.1016/S0960-894X(00)00670-3 1:CAS:528:DC%2BD3MXhtFyls74%3D
-
Macor JE, Gurley D, Lanthorn T et al (2001) The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. Bioorg Med Chem Lett 11:319-321
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 319-321
-
-
MacOr, J.E.1
Gurley, D.2
Lanthorn, T.3
-
66
-
-
0027325496
-
Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia
-
8398945 10.1016/0920-9964(93)90048-N 1:STN:280:DyaK2c%2FgtFOlsA%3D%3D
-
Cullum CM, Harris JG, Waldo MC et al (1993) Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophr Res 10:131-141
-
(1993)
Schizophr Res
, vol.10
, pp. 131-141
-
-
Cullum, C.M.1
Harris, J.G.2
Waldo, M.C.3
-
67
-
-
44949100606
-
Exacerbation of recurrent depression as a result of treatment with varenicline
-
18519539 10.1176/appi.ajp.2008.07111735
-
Popkin MK (2008) Exacerbation of recurrent depression as a result of treatment with varenicline. Am J Psychiatry 165:774
-
(2008)
Am J Psychiatry
, vol.165
, pp. 774
-
-
Popkin, M.K.1
-
68
-
-
77954611225
-
A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia
-
20573264 10.1186/1744-859X-9-27
-
Shiina A, Shirayama Y, Niitsu T et al (2010) A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia. Ann Gen Psychiatry 9:27
-
(2010)
Ann Gen Psychiatry
, vol.9
, pp. 27
-
-
Shiina, A.1
Shirayama, Y.2
Niitsu, T.3
-
69
-
-
84855866544
-
Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: A randomized double-blind placebo-controlled trial
-
22048460 10.1038/npp.2011.238 1:CAS:528:DC%2BC38XnslOkuw%3D%3D
-
Shim JC, Jung DU, Jung SS et al (2012) Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: a randomized double-blind placebo-controlled trial. Neuropsychopharmacology 37:660-668
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 660-668
-
-
Shim, J.C.1
Jung, D.U.2
Jung, S.S.3
-
70
-
-
34548071446
-
Exacerbation of schizophrenia by varenicline
-
17671295 10.1176/appi.ajp.2007.07020326
-
Freedman R (2007) Exacerbation of schizophrenia by varenicline. Am J Psychiatry 164:1269
-
(2007)
Am J Psychiatry
, vol.164
, pp. 1269
-
-
Freedman, R.1
-
71
-
-
77956182638
-
Schizophrenia, "just the facts" 5. Treatment and prevention. Past, present, and future
-
20655178 10.1016/j.schres.2010.05.025
-
Tandon R, Nasrallah HA, Keshavan MS (2010) Schizophrenia, "just the facts" 5. Treatment and prevention. Past, present, and future. Schizophr Res 122:1-23
-
(2010)
Schizophr Res
, vol.122
, pp. 1-23
-
-
Tandon, R.1
Nasrallah, H.A.2
Keshavan, M.S.3
-
72
-
-
84856080078
-
Psychopharmacological treatment of schizophrenia: What do we have, and what could we get?
-
21420988 10.1016/j.neuropharm.2011.03.013 1:CAS:528:DC%2BC38XhtFWksL4%3D
-
Ellenbroek BA (2012) Psychopharmacological treatment of schizophrenia: what do we have, and what could we get? Neuropharmacology 62:1371-1380
-
(2012)
Neuropharmacology
, vol.62
, pp. 1371-1380
-
-
Ellenbroek, B.A.1
-
73
-
-
83055178597
-
Novartis to shut brain research facility
-
22158218 10.1038/480161a 1:CAS:528:DC%2BC3MXhsF2jtL3O
-
Abbott A (2011) Novartis to shut brain research facility. Nature 480:161-162
-
(2011)
Nature
, vol.480
, pp. 161-162
-
-
Abbott, A.1
-
74
-
-
40849110964
-
Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial
-
18303965 10.2217/14622416.9.3.289 1:CAS:528:DC%2BD1cXis1Wiu7Y%3D
-
Lavedan C, Volpi S, Polymeropoulos MH, Wolfgang CD (2008) Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial. Pharmacogenomics 9:289-301
-
(2008)
Pharmacogenomics
, vol.9
, pp. 289-301
-
-
Lavedan, C.1
Volpi, S.2
Polymeropoulos, M.H.3
Wolfgang, C.D.4
-
75
-
-
84944618044
-
-
Food and Drug Administration Accessed on Feb 18, 2013.
-
Food and Drug Administration. Drug approval package Fanapt (iloperidone) tablets: http://www.accessdata.fda.gov/drugsatfda-docs/label/2013/022192s007lbl. pdf; Accessed on Feb 18, 2013.
-
Drug Approval Package Fanapt (Iloperidone) Tablets
-
-
-
76
-
-
84880443557
-
-
Food and Drug Administration Accessed on Feb 18, 2013.
-
Food and Drug Administration. Drug approval package Saphris (asenapine) tablets: http://www.accessdata.fda.gov/drugsatfda-docs/label/2012/022117s013lbl. pdf; Accessed on Feb 18, 2013.
-
Drug Approval Package Saphris (Asenapine) Tablets
-
-
-
77
-
-
84944618044
-
-
Food and Drug Administration Accessed on Feb 18, 2013
-
Food and Drug Administration. Drug approval package Latuda (lurasidone hydrochloride) tablets: http://www.accessdata.fda.gov/drugsatfda-docs/label/ 2013/200603s009s013lbl.pdf; Accessed on Feb 18, 2013.
-
Drug Approval Package Latuda (Lurasidone Hydrochloride) Tablets
-
-
-
78
-
-
84875685915
-
Population pharmacokinetics of blonanserin in Chinese healthy volunteers and the effect of the food intake
-
doi: 10.1002/hup.2290
-
Wen YG, Shang DW, Xie HZ et al (2013) Population pharmacokinetics of blonanserin in Chinese healthy volunteers and the effect of the food intake. Hum Psychopharmacol. doi: 10.1002/hup.2290
-
(2013)
Hum Psychopharmacol.
-
-
Wen, Y.G.1
Shang, D.W.2
Xie, H.Z.3
-
79
-
-
84880443055
-
-
A Study of LY2140023 in Patients with Schizophrenia. Clinical Trials.gov [updated 30 March 2012, cited 2012 Apr 14]
-
A Study of LY2140023 in Patients with Schizophrenia. Clinical Trials.gov [updated 30 March 2012, cited 2012 Apr 14] Available from [ http:// clinicaltrials.gov/ct2/show/NCT01307800?term=NCT01307800&rank=1 ]
-
-
-
-
80
-
-
84880426352
-
-
A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients. Clinical Trials.gov [updated 17 February 2012, cited 2012 Apr 14]
-
A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients. Clinical Trials.gov [updated 17 February 2012, cited 2012 Apr 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT01328093?term= NCT01328093&rank=1 ]
-
-
-
-
81
-
-
77249083031
-
Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia
-
19995568 10.1016/j.pbb.2009.12.002 1:CAS:528:DC%2BC3cXitVOgtrc%3D
-
Schlumberger C, Pietraszek M, Gravius A, Danysz W (2010) Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia. Pharmacol Biochem Behav 95:23-30
-
(2010)
Pharmacol Biochem Behav
, vol.95
, pp. 23-30
-
-
Schlumberger, C.1
Pietraszek, M.2
Gravius, A.3
Danysz, W.4
-
82
-
-
72849132183
-
Improvement of negative and positive symptoms in treatment-refractory schizophrenia: A double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine
-
19906345 10.4088/JCP.08m04935gry
-
de Lucena D, Fernandes BS, Berk M et al (2009) Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. J Clin Psychiatry 70:1416-1423
-
(2009)
J Clin Psychiatry
, vol.70
, pp. 1416-1423
-
-
De Lucena, D.1
Fernandes, B.S.2
Berk, M.3
-
83
-
-
62349116484
-
A randomized, placebo-controlled study of memantine as adjunctive treatment in patients with schizophrenia
-
19005465 10.1038/npp.2008.200 1:CAS:528:DC%2BD1MXjtFentL4%3D
-
Lieberman JA, Papadakis K, Csernansky J et al (2009) A randomized, placebo-controlled study of memantine as adjunctive treatment in patients with schizophrenia. Neuropsychopharmacology 34:1322-1329
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1322-1329
-
-
Lieberman, J.A.1
Papadakis, K.2
Csernansky, J.3
-
84
-
-
79953316447
-
Glycine transporter-1: A new potential therapeutic target for schizophrenia
-
21355838 10.2174/138161211795049598 1:CAS:528:DC%2BC3MXltVSmsbg%3D
-
Hashimoto K (2011) Glycine transporter-1: a new potential therapeutic target for schizophrenia. Curr Pharm Des 17:112-120
-
(2011)
Curr Pharm des
, vol.17
, pp. 112-120
-
-
Hashimoto, K.1
-
85
-
-
34249079802
-
Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers
-
17119538 10.1038/sj.npp.1301257 1:CAS:528:DC%2BD2sXltlaqtbc%3D
-
Wezenberg E, Verkes RJ, Ruigt GS, Hulstijn W, Sabbe BG (2007) Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology 32:1272-1283
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1272-1283
-
-
Wezenberg, E.1
Verkes, R.J.2
Ruigt, G.S.3
Hulstijn, W.4
Sabbe, B.G.5
-
86
-
-
84880440571
-
-
Evaluation of Single and Repeat Doses of GSK729327 in Healthy Volunteers. Clinical Trials.gov [updated 14 October 2010, cited 2012 Apr 14]
-
Evaluation of Single and Repeat Doses of GSK729327 in Healthy Volunteers. Clinical Trials.gov [updated 14 October 2010, cited 2012 Apr 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT00448890?term=NCT00448890&rank=1 ]
-
-
-
-
87
-
-
84859648778
-
Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission
-
10.1007/s00213-011-2554-3 1:CAS:528:DC%2BC3MXhsVektrrJ
-
Jardemark K, Marcus MM, Malmerfelt A, Shahid M, Svensson TH (2012) Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission. Psychopharmacology (Berl) 221:115-131
-
(2012)
Psychopharmacology (Berl)
, vol.221
, pp. 115-131
-
-
Jardemark, K.1
Marcus, M.M.2
Malmerfelt, A.3
Shahid, M.4
Svensson, T.H.5
-
88
-
-
84880439246
-
-
Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study. Clinical Trials.gov [updated 14 October 2011, cited 2012 Apr 14]
-
Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study. Clinical Trials.gov [updated 14 October 2011, cited 2012 Apr 14]Available from [ http://clinicaltrials.gov/ct2/show/NCT00129441?term=NCT+00129441&rank=1 ]
-
-
-
-
89
-
-
84880399673
-
-
Treating Schizophrenia by Correcting Abnormal Brain Development. Clinical Trials.gov [updated 28 July 2011, cited 2012 Apr 14]
-
Treating Schizophrenia by Correcting Abnormal Brain Development. Clinical Trials.gov [updated 28 July 2011, cited 2012 Apr 14]Available from [ http://clinicaltrials.gov/ct2/show/NCT00179465?term=NCT00179465&rank=1 ]
-
-
-
-
90
-
-
84880427509
-
-
A Study to Examine the Pharmacodynamic Effects of GSK1034702 on Neurophysiological Biomarkers of Cognition in Nicotine Abstained Otherwise Healthy Smokers (MAA113746). Clinical Trials.gov [updated 9 June 2011, cited 2012 Apr 14]
-
A Study to Examine the Pharmacodynamic Effects of GSK1034702 on Neurophysiological Biomarkers of Cognition in Nicotine Abstained Otherwise Healthy Smokers (MAA113746). Clinical Trials.gov [updated 9 June 2011, cited 2012 Apr 14]Available from [ http://clinicaltrials.gov/ct2/show/NCT01371799? term=NCT01371799&rank=1
-
-
-
-
91
-
-
72049088792
-
AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model
-
19835892 10.1016/j.neuropharm.2009.10.003 1:CAS:528:DC%2BD1MXhsFymsLfO
-
Bradley SR, Lameh J, Ohrmund L et al (2010) AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model. Neuropharmacology 58:365-373
-
(2010)
Neuropharmacology
, vol.58
, pp. 365-373
-
-
Bradley, S.R.1
Lameh, J.2
Ohrmund, L.3
-
92
-
-
84880434080
-
-
Pharmacologic and Clinical Testing of a D1 Agonist for Cognitive Enhancement in Neuropsychiatric Disorders. Clinical Trials.gov [updated 24 January 2012, cited 2012 Apr 14]
-
Pharmacologic and Clinical Testing of a D1 Agonist for Cognitive Enhancement in Neuropsychiatric Disorders. Clinical Trials.gov [updated 24 January 2012, cited 2012 Apr 14]Available from [ http://clinicaltrials.gov/ct2/ show/NCT01519557?term=NCT01519557&rank=1
-
-
-
-
93
-
-
84858405528
-
A placebo-controlled study of the modafinil added to risperidone in chronic schizophrenia
-
10.1007/s00213-011-2513-z 1:CAS:528:DC%2BC3MXht1Wrs7vL
-
Arbabi M, Bagheri M, Rezaei F et al (2012) A placebo-controlled study of the modafinil added to risperidone in chronic schizophrenia. Psychopharmacology (Berl) 220:591-598
-
(2012)
Psychopharmacology (Berl)
, vol.220
, pp. 591-598
-
-
Arbabi, M.1
Bagheri, M.2
Rezaei, F.3
-
94
-
-
84880405027
-
-
Efficacy, Safety, and Tolerability of SPD489 in Adults with Schizophrenia and Predominant Negative Symptoms. Clinical Trials.gov [updated 2 February 2012, cited 2012 Apr 14]
-
Efficacy, Safety, and Tolerability of SPD489 in Adults with Schizophrenia and Predominant Negative Symptoms. Clinical Trials.gov [updated 2 February 2012, cited 2012 Apr 14] Available from [ http://clinicaltrials.gov/ct2/show/ NCT00922272?term=NCT00922272&rank=1
-
-
-
-
95
-
-
84880445098
-
-
Clinical Trial of Tolcapone for Cognition in Schizophrenia. Clinical Trials.gov [updated 20 March 2012, cited 2012 Apr 14]
-
Clinical Trial of Tolcapone for Cognition in Schizophrenia. Clinical Trials.gov [updated 20 March 2012, cited 2012 Apr 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT00044083?term=NCT00044083&rank=1
-
-
-
-
96
-
-
84862609103
-
Serotonin Receptors as Targets for Drugs Useful to Treat Psychosis and Cognitive Impairment in Schizophrenia
-
Jan 26.[Abstract]
-
Meltzer HY, Massey BW, Horiguchi M (2012) Serotonin Receptors as Targets for Drugs Useful to Treat Psychosis and Cognitive Impairment in Schizophrenia. Curr Pharm Biotechnol. Jan 26.[Abstract]
-
(2012)
Curr Pharm Biotechnol.
-
-
Meltzer, H.Y.1
Massey, B.W.2
Horiguchi, M.3
-
97
-
-
84880447722
-
-
Safety and Cognitive Function Study of EVP-6124 in Patients with Schizophrenia. Clinical Trials.gov [updated 5 March 2012, cited 2012 April 14]
-
Safety and Cognitive Function Study of EVP-6124 in Patients with Schizophrenia. Clinical Trials.gov [updated 5 March 2012, cited 2012 April 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT00968851?term= NCT00968851&rank=1
-
-
-
-
98
-
-
84865025138
-
PNU-120596, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors, reverses a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats
-
doi: 10.1177/0269881111431747
-
McLean SL, Idris N, Grayson B et al (2011) PNU-120596, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors, reverses a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats. J Psychopharmacol. doi: 10.1177/ 0269881111431747
-
(2011)
J Psychopharmacol.
-
-
McLean, S.L.1
Idris, N.2
Grayson, B.3
-
99
-
-
84880413316
-
-
Efficacy, Safety, and Tolerability of TC-5619 as Augmentation Therapy to Improve Negative Symptoms and Cognition in Outpatients with Schizophrenia. Clinical Trials.gov [updated 6 March 2012, cited 2012 April 14]
-
Efficacy, Safety, and Tolerability of TC-5619 as Augmentation Therapy to Improve Negative Symptoms and Cognition in Outpatients with Schizophrenia. Clinical Trials.gov [updated 6 March 2012, cited 2012 April 14]. Available from [ http://clinicaltrials.gov/ct2/show/NCT01488929?term=NCT01488929&rank=1
-
-
-
-
100
-
-
65649092520
-
Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders
-
19223665 10.1124/jpet.108.150094 1:CAS:528:DC%2BD1MXlt1Omu74%3D
-
Roncarati R, Scali C, Comery TA et al (2009) Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. J Pharmacol Exp Ther 329:459-468
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 459-468
-
-
Roncarati, R.1
Scali, C.2
Comery, T.A.3
-
101
-
-
77957241598
-
Adjunctive alpha2-adrenoceptor blockade enhances the antipsychotic-like effect of risperidone and facilitates cortical dopaminergic and glutamatergic, NMDA receptor-mediated transmission
-
19835668 10.1017/S1461145709990794 1:CAS:528:DC%2BC3cXpt1Gjsbk%3D
-
Marcus MM, Wiker C, Franberg O et al (2010) Adjunctive alpha2-adrenoceptor blockade enhances the antipsychotic-like effect of risperidone and facilitates cortical dopaminergic and glutamatergic, NMDA receptor-mediated transmission. Int J Neuropsychopharmacol 13:891-903
-
(2010)
Int J Neuropsychopharmacol
, vol.13
, pp. 891-903
-
-
Marcus, M.M.1
Wiker, C.2
Franberg, O.3
-
102
-
-
45749156388
-
Antipsychotic-like properties of phosphodiesterase 4 inhibitors: Evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle
-
18420599 10.1124/jpet.108.138586 1:CAS:528:DC%2BD1cXotlyltro%3D
-
Halene TB, Siegel SJ (2008) Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2- imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle. J Pharmacol Exp Ther 326:230-239
-
(2008)
J Pharmacol Exp Ther
, vol.326
, pp. 230-239
-
-
Halene, T.B.1
Siegel, S.J.2
-
103
-
-
84655170136
-
Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia
-
22142545 10.1016/j.bmcl.2011.11.023
-
Yang SW, Smotryski J, McElroy WT et al (2012) Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg Med Chem Lett 22:235-239
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 235-239
-
-
Yang, S.W.1
Smotryski, J.2
McElroy, W.T.3
-
104
-
-
57049110877
-
Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040
-
10.1007/s00213-008-1310-9 1:CAS:528:DC%2BD1cXhsVenu77M
-
Southam E, Cilia J, Gartlon JE et al (2009) Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040. Psychopharmacology (Berl) 201:483-494
-
(2009)
Psychopharmacology (Berl)
, vol.201
, pp. 483-494
-
-
Southam, E.1
Cilia, J.2
Gartlon, J.E.3
-
105
-
-
60949099290
-
Effects of TRK-820, a selective kappa opioid receptor agonist, on rat schizophrenia models
-
19374836 10.1016/j.ejphar.2009.01.043 1:CAS:528:DC%2BD1MXivVehsbk%3D
-
Yoshikawa S, Hareyama N, Ikeda K et al (2009) Effects of TRK-820, a selective kappa opioid receptor agonist, on rat schizophrenia models. Eur J Pharmacol 606:102-108
-
(2009)
Eur J Pharmacol
, vol.606
, pp. 102-108
-
-
Yoshikawa, S.1
Hareyama, N.2
Ikeda, K.3
-
106
-
-
77649112679
-
A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia
-
19895780 10.4088/JCP.08m04666yel 1:CAS:528:DC%2BC3cXktVSgt7w%3D
-
Levkovitz Y, Mendlovich S, Riwkes S et al (2010) A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia. J Clin Psychiatry 71:138-149
-
(2010)
J Clin Psychiatry
, vol.71
, pp. 138-149
-
-
Levkovitz, Y.1
Mendlovich, S.2
Riwkes, S.3
-
107
-
-
77955050321
-
Celecoxib treatment in an early stage of schizophrenia: Results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment
-
20570110 10.1016/j.schres.2010.04.015
-
Muller N, Krause D, Dehning S et al (2010) Celecoxib treatment in an early stage of schizophrenia: results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment. Schizophr Res 121:118-124
-
(2010)
Schizophr Res
, vol.121
, pp. 118-124
-
-
Muller, N.1
Krause, D.2
Dehning, S.3
-
108
-
-
80052638461
-
Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophrenia
-
21840177 10.1016/j.schres.2011.07.027
-
Pedersen CA, Gibson CM, Rau SW et al (2011) Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophrenia. Schizophr Res 132:50-53
-
(2011)
Schizophr Res
, vol.132
, pp. 50-53
-
-
Pedersen, C.A.1
Gibson, C.M.2
Rau, S.W.3
-
109
-
-
84857997678
-
Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia
-
22169248 10.1016/j.schres.2011.11.001
-
Javitt DC, Buchanan RW, Keefe RS et al (2012) Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia. Schizophr Res 136:25-31
-
(2012)
Schizophr Res
, vol.136
, pp. 25-31
-
-
Javitt, D.C.1
Buchanan, R.W.2
Keefe, R.S.3
-
110
-
-
84880398202
-
-
Study of Talnetant versus Placebo and Risperidone In Schizophrenia. Clinical Trials.gov [updated 1 March 2012, cited 2012 April 14]
-
Study of Talnetant versus Placebo and Risperidone In Schizophrenia. Clinical Trials.gov [updated 1 March 2012, cited 2012 April 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT00103727?term=NCT00103727&rank=1
-
-
-
-
111
-
-
84861531595
-
A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder
-
10.1016/j.schres.2011.11.001
-
Weiser M, Gershon AA, Rubinstein K et al (2012) A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder. Schizophr Res 136:25-31
-
(2012)
Schizophr Res
, vol.136
, pp. 25-31
-
-
Weiser, M.1
Gershon, A.A.2
Rubinstein, K.3
-
112
-
-
84880447080
-
-
Rasagiline in the Treatment of Persistent Negative Symptoms of Schizophrenia. Clinical Trials.gov [updated 23 April 2011, cited 2012 April 14]
-
Rasagiline in the Treatment of Persistent Negative Symptoms of Schizophrenia. Clinical Trials.gov [updated 23 April 2011, cited 2012 April 14] Available from [ http://clinicaltrials.gov/ct2/show/NCT00492336?term= NCT00492336&rank=1
-
-
-
-
113
-
-
84880415118
-
-
Bexarotene Augmentation of Antipsychotic Treatment for Chronic Schizophrenia. Clinical Trials.gov [updated 28 June 2010, cited 2012 April 14]
-
Bexarotene Augmentation of Antipsychotic Treatment for Chronic Schizophrenia. Clinical Trials.gov [updated 28 June 2010, cited 2012 April 14]. Available from [ http://clinicaltrials.gov/ct2/show?term=NCT00141947&rank=2
-
-
-
|