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Volumn 12, Issue 14, 2013, Pages 2194-2199

Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes

Author keywords

Cancer; HLX1; Homeobox; HOXA9; Polycomb; Senescence

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; HLX1 PROTEIN; HOMEODOMAIN PROTEIN; INTERSTITIAL COLLAGENASE; POLYCOMB REPRESSIVE COMPLEX 2; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG;

EID: 84880417938     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25331     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 78349257844 scopus 로고    scopus 로고
    • The essence of senescence
    • PMID:21078816
    • Kuilman T, Michaloglou C, Mooi WJ, Peeper DS. The essence of senescence. Genes Dev 2010; 24:2463-79; PMID:21078816; http://dx.doi.org/10.1101/gad.1971610
    • (2010) Genes Dev , vol.24 , pp. 2463-2479
    • Kuilman, T.1    Michaloglou, C.2    Mooi, W.J.3    Peeper, D.S.4
  • 2
    • 58849154235 scopus 로고    scopus 로고
    • Senescence-messaging secretome: SMS-ing cellular stress
    • PMID:19132009
    • Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer 2009; 9:81-94; PMID:19132009; http://dx.doi.org/10.1038/ nrc2560
    • (2009) Nat Rev Cancer , vol.9 , pp. 81-94
    • Kuilman, T.1    Peeper, D.S.2
  • 3
    • 70349093119 scopus 로고    scopus 로고
    • Senescence impairs successful reprogramming to pluripotent stem cells
    • PMID:19696146
    • Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I, et al. Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev 2009; 23:2134-9; PMID:19696146; http://dx.doi.org/10.1101/gad.1811609
    • (2009) Genes Dev , vol.23 , pp. 2134-2139
    • Banito, A.1    Rashid, S.T.2    Acosta, J.C.3    Li, S.4    Pereira, C.F.5    Geti, I.6
  • 4
    • 69349103956 scopus 로고    scopus 로고
    • The Ink4/Arf locus is a barrier for iPS cell reprogramming
    • PMID:19668188
    • Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 2009; 460:1136-9; PMID:19668188; http://dx.doi.org/10.1038/nature08290
    • (2009) Nature , vol.460 , pp. 1136-1139
    • Li, H.1    Collado, M.2    Villasante, A.3    Strati, K.4    Ortega, S.5    Cañamero, M.6
  • 5
    • 33747587608 scopus 로고    scopus 로고
    • Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
    • DOI 10.1038/nrm1987, PII NRM1987
    • Gil J, Peters G. Regulation of the INK4b-ARFINK4a tumour suppressor locus: all for one or one for all. Nat Rev Mol Cell Biol 2006; 7:667-77; PMID:16921403; http://dx.doi.org/10.1038/nrm1987 (Pubitemid 44268212)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.9 , pp. 667-677
    • Gil, J.1    Peters, G.2
  • 7
    • 78449243068 scopus 로고    scopus 로고
    • Epigenetic regulation of the INK4b- ARF-INK4a locus: In sickness and in health
    • PMID:20716961
    • Popov N, Gil J. Epigenetic regulation of the INK4b- ARF-INK4a locus: in sickness and in health. Epigenetics 2010; 5:685-90; PMID:20716961; http://dx.doi.org/10.4161/epi.5.8.12996
    • (2010) Epigenetics , vol.5 , pp. 685-690
    • Popov, N.1    Gil, J.2
  • 8
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • PMID:10581039
    • van der Vlag J, Otte AP. Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat Genet 1999; 23:474-8; PMID:10581039; http://dx.doi.org/10.1038/70602
    • (1999) Nat Genet , vol.23 , pp. 474-478
    • Van Der Vlag, J.1    Otte, A.P.2
  • 9
    • 70449787940 scopus 로고    scopus 로고
    • Polycomb group complexes-many combinations, many functions
    • PMID:19889541
    • Kerppola TK. Polycomb group complexes-many combinations, many functions. Trends Cell Biol 2009; 19:692-704; PMID:19889541; http://dx.doi.org/10.1016/j. tcb.2009.10.001
    • (2009) Trends Cell Biol , vol.19 , pp. 692-704
    • Kerppola, T.K.1
  • 10
    • 78751590899 scopus 로고    scopus 로고
    • Silencing chromatin: Comparing modes and mechanisms
    • PMID:21221116
    • Beisel C, Paro R. Silencing chromatin: comparing modes and mechanisms. Nat Rev Genet 2011; 12:123-35; PMID:21221116; http://dx.doi.org/10.1038/nrg2932
    • (2011) Nat Rev Genet , vol.12 , pp. 123-135
    • Beisel, C.1    Paro, R.2
  • 11
    • 77954758157 scopus 로고    scopus 로고
    • Polycomb group protein-mediated repression of transcription
    • PMID:20346678
    • Morey L, Helin K. Polycomb group protein-mediated repression of transcription. Trends Biochem Sci 2010; 35:323-32; PMID:20346678; http://dx.doi.org/10.1016/j.tibs.2010.02.009
    • (2010) Trends Biochem Sci , vol.35 , pp. 323-332
    • Morey, L.1    Helin, K.2
  • 13
    • 70350500219 scopus 로고    scopus 로고
    • Polycomb group proteins: Navigators of lineage pathways led astray in cancer
    • PMID:19851313
    • Bracken AP, Helin K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 2009; 9:773-84; PMID:19851313; http://dx.doi.org/10.1038/nrc2736
    • (2009) Nat Rev Cancer , vol.9 , pp. 773-784
    • Bracken, A.P.1    Helin, K.2
  • 14
    • 77957859982 scopus 로고    scopus 로고
    • A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1
    • PMID:20808772
    • Negishi M, Saraya A, Mochizuki S, Helin K, Koseki H, Iwama A. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1. PLoS One 2010; 5:e12373; PMID:20808772; http://dx.doi.org/10.1371/journal.pone.0012373
    • (2010) PLoS One , vol.5
    • Negishi, M.1    Saraya, A.2    Mochizuki, S.3    Helin, K.4    Koseki, H.5    Iwama, A.6
  • 15
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • PMID:20818389
    • Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY, Yang WH, et al. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol 2010; 12:982-92; PMID:20818389; http://dx.doi.org/10.1038/ncb2099
    • (2010) Nat Cell Biol , vol.12 , pp. 982-992
    • Yang, M.H.1    Hsu, D.S.2    Wang, H.W.3    Wang, H.J.4    Lan, H.Y.5    Yang, W.H.6
  • 16
    • 67650921949 scopus 로고    scopus 로고
    • Many human large intergenic noncoding RNAs associate with chromatin- modifying complexes and affect gene expression
    • PMID:19571010
    • Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, et al. Many human large intergenic noncoding RNAs associate with chromatin- modifying complexes and affect gene expression. Proc Natl Acad Sci USA 2009; 106:11667-72; PMID:19571010; http://dx.doi.org/10.1073/pnas.0904715106
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11667-11672
    • Khalil, A.M.1    Guttman, M.2    Huarte, M.3    Garber, M.4    Raj, A.5    Rivea Morales, D.6
  • 17
    • 84875921843 scopus 로고    scopus 로고
    • Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation
    • PMID:23455154
    • Martin N, Popov N, Aguilo F, O'Loghlen A, Raguz S, Snijders AP, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation. EMBO J 2013; 32:982-95; PMID:23455154; http://dx.doi.org/ 10.1038/emboj.2013.37
    • (2013) EMBO J , vol.32 , pp. 982-995
    • Martin, N.1    Popov, N.2    Aguilo, F.3    O'loghlen, A.4    Raguz, S.5    Snijders, A.P.6
  • 18
    • 77951605788 scopus 로고    scopus 로고
    • The Hox genes and their roles in oncogenesis
    • PMID:20357775
    • Shah N, Sukumar S. The Hox genes and their roles in oncogenesis. Nat Rev Cancer 2010; 10:361-71; PMID:20357775; http://dx.doi.org/10.1038/nrc2826
    • (2010) Nat Rev Cancer , vol.10 , pp. 361-371
    • Shah, N.1    Sukumar, S.2
  • 19
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • PMID:21151178
    • Kotake Y, Nakagawa T, Kitagawa K, Suzuki S, Liu N, Kitagawa M, et al. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene 2011; 30:1956-62; PMID:21151178; http://dx.doi.org/10.1038/onc.2010.568
    • (2011) Oncogene , vol.30 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3    Suzuki, S.4    Liu, N.5    Kitagawa, M.6
  • 20
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • PMID:20541999
    • Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 2010; 38:662-74; PMID:20541999; http://dx.doi.org/10.1016/j.molcel.2010.03.021
    • (2010) Mol Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Muñoz-Cabello, A.M.3    Raguz, S.4    Zeng, L.5    Mujtaba, S.6
  • 21
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • PMID:16618801
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006; 20:1123-36; PMID:16618801; http://dx.doi.org/10.1101/gad.381706
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 23
    • 33746616991 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
    • PMID:16862142
    • Kortlever RM, Higgins PJ, Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 2006; 8:877-84; PMID:16862142; http://dx.doi.org/10. 1038/ncb1448
    • (2006) Nat Cell Biol , vol.8 , pp. 877-884
    • Kortlever, R.M.1    Higgins, P.J.2    Bernards, R.3
  • 24
    • 77954243065 scopus 로고    scopus 로고
    • The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
    • PMID:20526329
    • Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol 2010; 12:676-85; PMID:20526329; http://dx.doi.org/10.1038/ncb2070
    • (2010) Nat Cell Biol , vol.12 , pp. 676-685
    • Jun, J.I.1    Lau, L.F.2
  • 26
    • 64549140317 scopus 로고    scopus 로고
    • A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a
    • PMID:19340300
    • Irelan JT, Gutierrez Del Arroyo A, Gutierrez A, Peters G, Quon KC, Miraglia L, et al. A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a. PLoS One 2009; 4:e5067; PMID:19340300; http://dx.doi.org/10.1371/journal.pone.0005067
    • (2009) PLoS One , vol.4
    • Irelan, J.T.1    Gutierrez Del Arroyo, A.2    Gutierrez, A.3    Peters, G.4    Quon, K.C.5    Miraglia, L.6
  • 27
    • 84862966022 scopus 로고    scopus 로고
    • Identification and characterization of Hoxa9 binding sites in hematopoietic cells
    • PMID:22072553
    • Huang Y, Sitwala K, Bronstein J, Sanders D, Dandekar M, Collins C, et al. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood 2012; 119:388-98; PMID:22072553; http://dx.doi.org/10.1182/blood- 2011-03-341081
    • (2012) Blood , vol.119 , pp. 388-398
    • Huang, Y.1    Sitwala, K.2    Bronstein, J.3    Sanders, D.4    Dandekar, M.5    Collins, C.6
  • 28
    • 84865132216 scopus 로고    scopus 로고
    • H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia
    • PMID:22897850
    • Kawahara M, Pandolfi A, Bartholdy B, Barreyro L, Will B, Roth M, et al. H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia. Cancer Cell 2012; 22:194-208; PMID:22897850; http://dx.doi.org/10. 1016/j.ccr.2012.06.027
    • (2012) Cancer Cell , vol.22 , pp. 194-208
    • Kawahara, M.1    Pandolfi, A.2    Bartholdy, B.3    Barreyro, L.4    Will, B.5    Roth, M.6
  • 29
    • 79957839752 scopus 로고    scopus 로고
    • Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells
    • PMID:21624810
    • Smith LL, Yeung J, Zeisig BB, Popov N, Huijbers I, Barnes J, et al. Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells. Cell Stem Cell 2011; 8:649-62; PMID:21624810; http://dx.doi.org/10.1016/j.stem.2011.05.004
    • (2011) Cell Stem Cell , vol.8 , pp. 649-662
    • Smith, L.L.1    Yeung, J.2    Zeisig, B.B.3    Popov, N.4    Huijbers, I.5    Barnes, J.6
  • 31
    • 39849096853 scopus 로고    scopus 로고
    • The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing
    • DOI 10.1038/sj.onc.1210774, PII 1210774
    • Nuytten M, Beke L, Van Eynde A, Ceulemans H, Beullens M, Van Hummelen P, et al. The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. Oncogene 2008; 27:1449-60; PMID:17724462; http://dx.doi.org/10.1038/sj.onc.1210774 (Pubitemid 351317463)
    • (2008) Oncogene , vol.27 , Issue.10 , pp. 1449-1460
    • Nuytten, M.1    Beke, L.2    Van Eynde, A.3    Ceulemans, H.4    Beullens, M.5    Van Hummelen, P.6    Fuks, F.7    Bollen, M.8
  • 32
    • 53649109801 scopus 로고    scopus 로고
    • Critical pathways in cellular senescence and immortalization revealed by gene expression profiling
    • PMID:18711403
    • Fridman AL, Tainsky MA. Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. Oncogene 2008; 27:5975-87; PMID:18711403; http://dx.doi.org/10.1038/onc.2008.213
    • (2008) Oncogene , vol.27 , pp. 5975-5987
    • Fridman, A.L.1    Tainsky, M.A.2
  • 33
    • 64049095814 scopus 로고    scopus 로고
    • HOXA9 is required for survival in human MLL-rearranged acute leukemias
    • PMID:19056693
    • Faber J, Krivtsov AV, Stubbs MC, Wright R, Davis TN, van den Heuvel-Eibrink M, et al. HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 2009; 113:2375-85; PMID:19056693; http://dx.doi.org/10. 1182/blood-2007-09-113597
    • (2009) Blood , vol.113 , pp. 2375-2385
    • Faber, J.1    Krivtsov, A.V.2    Stubbs, M.C.3    Wright, R.4    Davis, T.N.5    Van Den Heuvel-Eibrink, M.6
  • 34
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40:499-507; PMID:18443585; http://dx.doi.org/10.1038/ng.127 (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 35
    • 77952716929 scopus 로고    scopus 로고
    • HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling
    • PMID:20504375
    • Kim YR, Oh KJ, Park RY, Xuan NT, Kang TW, Kwon DD, et al. HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling. Mol Cancer 2010; 9:124; PMID:20504375; http://dx.doi.org/10. 1186/1476-4598-9-124
    • (2010) Mol Cancer , vol.9 , pp. 124
    • Kim, Y.R.1    Oh, K.J.2    Park, R.Y.3    Xuan, N.T.4    Kang, T.W.5    Kwon, D.D.6
  • 36
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann A, van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 2006; 6:846-56; PMID:17060944; http://dx.doi.org/10.1038/nrc1991 (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 37
    • 55449105221 scopus 로고    scopus 로고
    • Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
    • PMID:18974828
    • Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet 2008; 4:e1000242; PMID:18974828; http://dx.doi.org/10.1371/journal. pgen.1000242
    • (2008) PLoS Genet , vol.4
    • Ku, M.1    Koche, R.P.2    Rheinbay, E.3    Mendenhall, E.M.4    Endoh, M.5    Mikkelsen, T.S.6
  • 38
    • 77951878056 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and senescence: Learning the biology to improve the technology
    • PMID:20379220
    • Banito A, Gil J. Induced pluripotent stem cells and senescence: learning the biology to improve the technology. EMBO Rep 2010; 11:353-9; PMID:20379220; http://dx.doi.org/10.1038/embor.2010.47
    • (2010) EMBO Rep , vol.11 , pp. 353-359
    • Banito, A.1    Gil, J.2
  • 39
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • DOI 10.1038/nature01572
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423:255-60; PMID:12714970; http://dx.doi.org/10.1038/nature01572 (Pubitemid 40852690)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2


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