No association of functional variant in pri-miR-218 and risk of congenital heart disease in a Chinese population

Gene

Volumn 523, Issue 2, 2013, Pages 173-177

  Gao, Xiaobo ^a,b,e   Yang, Liping ^c   Ma, Yan ^a,b   Yang, Juhua ^c   Zhang, Guican ^c   Huang, Guoying ^d   Huang, Qiuyu ^c   Chen, Liangwan ^c   Fu, Fangmeng ^c   Chen, Yandan ^c   Su, Dongmei ^a   Dong, Yi ^c   Ma, Xu ^a,b   Lu, Cailing ^a,b   Peng, Xiaozhong ^e  

^a NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^b GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d CHILDREN S HOSPITAL OF FUDAN UNIVERSITY   (China)

^e CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

Author keywords

Congenital heart disease; MicroRNA; Pri mir 218; Rs11134527; Single nucleotide polymorphism

Indexed keywords

MICRORNA; MICRORNA 218; UNCLASSIFIED DRUG; MIRN218 MICRORNA, HUMAN;

ALLELE; ARTICLE; CHINESE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DNA SEQUENCE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN; CASE CONTROL STUDY; CHEMISTRY; CHINA; CONFORMATION; CONGENITAL HEART MALFORMATION; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; GENOTYPE; NUCLEOTIDE SEQUENCE; RISK;

DANIO RERIO;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CASE-CONTROL STUDIES; CHINA; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEART DEFECTS, CONGENITAL; HUMANS; MICRORNAS; NUCLEIC ACID CONFORMATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; TRANSFECTION;

MLCS; MLOWN;

EID: 84880416653     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.03.119     Document Type: Article

References (31)

1. Alajez N.M., et al. MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res. 2011, 71:2381-2391.
2. Benson D.W., et al. Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways. J. Clin. Invest. 1999, 104:1567-1573.
3. Bentham J., Bhattacharya S. Genetic mechanisms controlling cardiovascular development. Ann. N. Y. Acad. Sci. 2008, 1123:10-19.
4. Betel D., Wilson M., Gabow A., Marks D.S., Sander C. The microRNA.org resource: targets and expression. Nucleic Acids Res. 2008, 36:D149-D153.
5. Bruneau B.G., et al. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 2001, 106:709-721.
6. Chen J., Wang D.Z. microRNAs in cardiovascular development. J. Mol. Cell. Cardiol. 2012, 52:949-957.
7. Chiavacci E., et al. MicroRNA 218 mediates the effects of Tbx5a over-expression on zebrafish heart development. PLoS One 2012, 7:e50536.
8. Clark K.L., Yutzey K.E., Benson D.W. Transcription factors and congenital heart defects. Annu. Rev. Physiol. 2006, 68:97-121.
9. Duan R., Pak C., Jin P. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum. Mol. Genet. 2007, 16:1124-1131.
10. Ewart J.L., et al. Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene. Development 1997, 124:1281-1292.
11. Fish J.E., et al. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development 2011, 138:1409-1419.
12. Gong J., et al. Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis. Hum. Mutat. 2012, 33:254-263.
13. Harnprasopwat R., Ha D., Toyoshima T., Lodish H., Tojo A., Kotani A. Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126. Biochem. Biophys. Res. Commun. 2010, 399:117-122.
14. He X., et al. MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI 1 polycomb ring finger oncogene. Mol. Med. 2013, 18:1491-1498.
15. Nemer M. Genetic insights into normal and abnormal heart development. Cardiovasc. Pathol. 2008, 17:48-54.
16. Olson E.N. A decade of discoveries in cardiac biology. Nat. Med. 2004, 10:467-474.
17. Olson E.N. Gene regulatory networks in the evolution and development of the heart. Science 2006, 313:1922-1927.
18. Plasterk R.H. Micro RNAs in animal development. Cell 2006, 124:877-881.
19. Rao P.K., et al. Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ. Res. 2009, 105:585-594.
20. Reaume A.G., et al. Cardiac malformation in neonatal mice lacking connexin43. Science 1995, 267:1831-1834.
21. Ryan B.M., Robles A.I., Harris C.C. Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer 2010, 10:389-402.
22. Schott J.J., et al. Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science 1998, 281:108-111.
23. Shi T.Y., et al. A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. BMC Cancer 2013, 13:19.
24. Slaby O., Bienertova-Vasku J., Svoboda M., Vyzula R. Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer. J. Cell. Mol. Med. 2012, 16:8-21.
25. Tatarano S., et al. miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. Int. J. Oncol. 2011, 39:13-21.
26. Uesugi A., et al. The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. Cancer Res. 2011, 71:5765-5778.
27. Wessels M.W., Willems P.J. Genetic factors in non-syndromic congenital heart malformations. Clin. Genet. 2010, 78:103-123.
28. Xu J., et al. Functional variant in microRNA-196a2 contributes to the susceptibility of congenital heart disease in a Chinese population. Hum. Mutat. 2009, 30:1231-1236.
29. Zhang L.S., et al. Association between pri-miR-218 polymorphism and risk of hepatocellular carcinoma in a Han Chinese population. DNA Cell Biol. 2012, 31:761-765.
30. Zhao Y., et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 2007, 129:303-317.
31. Zhou X., et al. Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women. Gynecol. Oncol. 2010, 117:287-290.